FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4708, 444 aa
1>>>pF1KB4708 444 - 444 aa - 444 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0400+/-0.000433; mu= 18.4644+/- 0.027
mean_var=57.4569+/-12.231, 0's: 0 Z-trim(109.8): 37 B-trim: 509 in 1/49
Lambda= 0.169201
statistics sampled from 18058 (18086) to 18058 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.212), width: 16
Scan time: 8.100
The best scores are: opt bits E(85289)
NP_004256 (OMIM: 606149) fatty acid desaturase 2 i ( 444) 3118 769.8 0
NP_001268430 (OMIM: 606149) fatty acid desaturase ( 422) 2641 653.3 3.4e-187
NP_001268431 (OMIM: 606149) fatty acid desaturase ( 413) 2637 652.3 6.6e-187
NP_068373 (OMIM: 606150) fatty acid desaturase 3 [ ( 445) 2051 509.3 8.1e-144
XP_011543325 (OMIM: 606150) PREDICTED: fatty acid ( 454) 2014 500.3 4.3e-141
NP_037534 (OMIM: 606148) fatty acid desaturase 1 [ ( 501) 1984 493.0 7.5e-139
XP_016873213 (OMIM: 606150) PREDICTED: fatty acid ( 491) 1793 446.4 8e-125
XP_016873212 (OMIM: 606150) PREDICTED: fatty acid ( 500) 1756 437.3 4.3e-122
XP_011543324 (OMIM: 606148) PREDICTED: fatty acid ( 430) 1753 436.6 6.2e-122
NP_683725 (OMIM: 250790,613218) cytochrome b5 isof ( 134) 210 59.7 5.6e-09
NP_001177736 (OMIM: 250790,613218) cytochrome b5 i ( 124) 208 59.2 7.3e-09
XP_011524137 (OMIM: 250790,613218) PREDICTED: cyto ( 98) 206 58.6 8.4e-09
NP_001905 (OMIM: 250790,613218) cytochrome b5 isof ( 98) 206 58.6 8.4e-09
NP_085056 (OMIM: 611964) cytochrome b5 type B [Hom ( 150) 203 58.0 2e-08
NP_057314 (OMIM: 608343) cytochrome b5 reductase 4 ( 521) 165 49.0 3.6e-05
>>NP_004256 (OMIM: 606149) fatty acid desaturase 2 isofo (444 aa)
initn: 3118 init1: 3118 opt: 3118 Z-score: 4110.6 bits: 769.8 E(85289): 0
Smith-Waterman score: 3118; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KB4 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL
370 380 390 400 410 420
430 440
pF1KB4 RALLDIIRSLKKSGKLWLDAYLHK
::::::::::::::::::::::::
NP_004 RALLDIIRSLKKSGKLWLDAYLHK
430 440
>>NP_001268430 (OMIM: 606149) fatty acid desaturase 2 is (422 aa)
initn: 2637 init1: 2637 opt: 2641 Z-score: 3481.7 bits: 653.3 E(85289): 3.4e-187
Smith-Waterman score: 2641; 96.7% identity (98.0% similar) in 393 aa overlap (53-444:35-422)
30 40 50 60 70 80
pF1KB4 WEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGH-YAGEDATDAFRAFHPDLEF
::.. :: .:.. ::::::::::::
NP_001 EAGPFVCVCVLLASIPTPQTPLLQASLPPFHPASA---GHPITGQQ--DAFRAFHPDLEF
10 20 30 40 50
90 100 110 120 130 140
pF1KB4 VGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHII
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB4 ALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFV
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB4 IGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNH
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB4 QHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALL
240 250 260 270 280 290
330 340 350 360 370 380
pF1KB4 FLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNF
300 310 320 330 340 350
390 400 410 420 430 440
pF1KB4 QIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAY
360 370 380 390 400 410
pF1KB4 LHK
:::
NP_001 LHK
420
>>NP_001268431 (OMIM: 606149) fatty acid desaturase 2 is (413 aa)
initn: 2637 init1: 2637 opt: 2637 Z-score: 3476.6 bits: 652.3 E(85289): 6.6e-187
Smith-Waterman score: 2637; 100.0% identity (100.0% similar) in 375 aa overlap (70-444:39-413)
40 50 60 70 80 90
pF1KB4 DRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEP
::::::::::::::::::::::::::::::
NP_001 RRVNSLMLYTLRSITSHRSSHPERWATSSQDAFRAFHPDLEFVGKFLKPLLIGELAPEEP
10 20 30 40 50 60
100 110 120 130 140 150
pF1KB4 SQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWI
70 80 90 100 110 120
160 170 180 190 200 210
pF1KB4 PTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB4 HHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYF
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB4 QYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQ
250 260 270 280 290 300
340 350 360 370 380 390
pF1KB4 MNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKI
310 320 330 340 350 360
400 410 420 430 440
pF1KB4 APLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 APLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
370 380 390 400 410
>>NP_068373 (OMIM: 606150) fatty acid desaturase 3 [Homo (445 aa)
initn: 2076 init1: 1064 opt: 2051 Z-score: 2703.0 bits: 509.3 E(85289): 8.1e-144
Smith-Waterman score: 2051; 62.6% identity (84.1% similar) in 446 aa overlap (1-444:1-445)
10 20 30 40 50
pF1KB4 MGKGGNQG--EGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQR
:: :. : :: :. . .::: ::.:. :. :.::::.:.::.:..:. .::::.:
NP_068 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 VIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRK
.:::...::::::::::: ::.:: :::.::::::::::::::: :....::::::..
NP_068 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 TAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWL
.::::.:: .. .:: .::.::.:.: .::. .. .: ::.:. ..::.:: ::::. :
NP_068 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 QHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHV
::: :: :...: :::...:::.:.::: ::.::: ::::::::::::::::::.. :
NP_068 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 FVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAW
:.::: . .:::::: .:::::.:: :::::::::: . :. . . :.: .:.:: :
NP_068 FLLGE-SSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLW
250 260 270 280 290
300 310 320 330 340 350
pF1KB4 AVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSS
:.:.: :::..:.::::. :.:::. .: ::::::::.:::::: :: .: .::: ::
NP_068 AASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 QLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKP
::.:::::: :.:..:::::::::::::::: ::::: ..::::::::::::. :. ::
NP_068 QLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKP
360 370 380 390 400 410
420 430 440
pF1KB4 LLRALLDIIRSLKKSGKLWLDAYLHK
.: ::.::.::::::: .:::::::.
NP_068 FLTALVDIVRSLKKSGDIWLDAYLHQ
420 430 440
>>XP_011543325 (OMIM: 606150) PREDICTED: fatty acid desa (454 aa)
initn: 2053 init1: 1064 opt: 2014 Z-score: 2654.0 bits: 500.3 E(85289): 4.3e-141
Smith-Waterman score: 2014; 61.1% identity (82.4% similar) in 455 aa overlap (1-444:1-454)
10 20 30 40 50
pF1KB4 MGKGGNQG--EGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQR
:: :. : :: :. . .::: ::.:. :. :.::::.:.::.:..:. .::::.:
XP_011 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 VIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRK
.:::...::::::::::: ::.:: :::.::::::::::::::: :....::::::..
XP_011 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 TAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWL
.::::.:: .. .:: .::.::.:.: .::. .. .: ::.:. ..::.:: ::::. :
XP_011 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 QHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHV
::: :: :...: :::...:::.:.::: ::.::: ::::::::::::::::::.. :
XP_011 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 FVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAW
:.::: . .:::::: .:::::.:: :::::::::: . :. . . :.: .:.:: :
XP_011 FLLGE-SSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLW
250 260 270 280 290
300 310 320 330 340 350
pF1KB4 AVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSS
:.:.: :::..:.::::. :.:::. .: ::::::::.:::::: :: .: .::: ::
XP_011 AASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSS
300 310 320 330 340 350
360 370 380 390 400
pF1KB4 QLTATCNVEQSFFNDWFSGHLNFQIEHH---------LFPTMPRHNLHKIAPLVKSLCAK
::.:::::: :.:..::::::::::::. ::: ::::: ..::::::::::
XP_011 QLAATCNVEPSLFTNWFSGHLNFQIEHQCQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAK
360 370 380 390 400 410
410 420 430 440
pF1KB4 HGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
::. :. ::.: ::.::.::::::: .:::::::.
XP_011 HGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
420 430 440 450
>>NP_037534 (OMIM: 606148) fatty acid desaturase 1 [Homo (501 aa)
initn: 2028 init1: 1030 opt: 1984 Z-score: 2613.8 bits: 493.0 E(85289): 7.5e-139
Smith-Waterman score: 1984; 63.4% identity (84.1% similar) in 440 aa overlap (11-444:64-501)
10 20 30
pF1KB4 MGKGGNQGEGAAEREVSVPT---FSWEEIQKHNLRTDRWL
::: .. :: :.:.:. ... .:::
NP_037 WSPRTPSTRLTAPAGPARGVARPAMAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB4 VIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPE
:::::::::.... .::::.:::.::::.:::: : ::: . .: :... ::::::.::
NP_037 VIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPE
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB4 EPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNG
.:: . ::...:..:: :: :.: :.:.:.::::::: : ::. :.. ::.:.. ::..
NP_037 QPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTS
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB4 WIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRH
..: :. : .:.. ::::::::::.:::::. :::::.:.::::::::: :.:::: :
NP_037 FLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMH
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB4 FQHHAKPNIFHKDPDVNMLH--VFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLI
:::::::: :.::::.:: : :.::. .: ::.: ::.::::::.:::::::: :.
NP_037 FQHHAKPNCFRKDPDINM-HPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALL
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB4 PMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFI-RFLESHWF
:.:::. :.. .: .:.:::::: ...:.:::.::.:. : : :.: : :: :::::.::
NP_037 PLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLG-LKAFLGLFFIVRFLESNWF
340 350 360 370 380 390
340 350 360 370 380 390
pF1KB4 VWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRH
::::::::: :.::.. :: :.:: :::::..: ::::::::::::::::::::::::
NP_037 VWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRH
400 410 420 430 440 450
400 410 420 430 440
pF1KB4 NLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
: ::.::::.::::::::::: :::: :. :::.:::.::.::::::::.
NP_037 NYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
460 470 480 490 500
>>XP_016873213 (OMIM: 606150) PREDICTED: fatty acid desa (491 aa)
initn: 1822 init1: 986 opt: 1793 Z-score: 2362.0 bits: 446.4 E(85289): 8e-125
Smith-Waterman score: 1793; 63.2% identity (83.5% similar) in 389 aa overlap (56-444:104-491)
30 40 50 60 70 80
pF1KB4 IQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKF
:.: :. . ::::::: ::.:: ::
XP_016 PPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGEALRDAQQDAFRAFHQDLNFVRKF
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB4 LKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALES
:.::::::::::::::: :....::::::...::::.:: .. .:: .::.::.:.:
XP_016 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB4 IAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHL
.::. .. .: ::.:. ..::.:: ::::. :::: :: :...: :::...:::.:.:
XP_016 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB4 KGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEY
:: ::.::: ::::::::::::::::::.. ::.::: . .:::::: .:::::.:: :
XP_016 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGE-SSVEYGKKKRRYLPYNQQHLY
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB4 FFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNF
::::::::: . :. . . :.: .:.:: ::.:.: :::..:.::::. :.:::.
XP_016 FFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVA
320 330 340 350 360 370
330 340 350 360 370 380
pF1KB4 IRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEH
.: ::::::::.:::::: :: .: .::: ::::.:::::: :.:..::::::::::::
XP_016 VRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEH
380 390 400 410 420 430
390 400 410 420 430 440
pF1KB4 HLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
:::: ::::: ..::::::::::::. :. ::.: ::.::.::::::: .:::::::.
XP_016 HLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ
440 450 460 470 480 490
>>XP_016873212 (OMIM: 606150) PREDICTED: fatty acid desa (500 aa)
initn: 1799 init1: 810 opt: 1756 Z-score: 2313.0 bits: 437.3 E(85289): 4.3e-122
Smith-Waterman score: 1756; 61.6% identity (81.7% similar) in 398 aa overlap (56-444:104-500)
30 40 50 60 70 80
pF1KB4 IQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKF
:.: :. . ::::::: ::.:: ::
XP_016 PPLGALDLTLQDARLEAPQAPLLTDRDSASGSRGRGEALRDAQQDAFRAFHQDLNFVRKF
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB4 LKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALES
:.::::::::::::::: :....::::::...::::.:: .. .:: .::.::.:.:
XP_016 LQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEV
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB4 IAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHL
.::. .. .: ::.:. ..::.:: ::::. :::: :: :...: :::...:::.:.:
XP_016 LAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQL
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB4 KGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEY
:: ::.::: ::::::::::::::::::.. ::.::: . .:::::: .:::::.:: :
XP_016 KGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGE-SSVEYGKKKRRYLPYNQQHLY
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB4 FFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNF
::::::::: . :. . . :.: .:.:: ::.:.: :::..:.::::. :.:::.
XP_016 FFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVA
320 330 340 350 360 370
330 340 350 360 370 380
pF1KB4 IRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEH
.: ::::::::.:::::: :: .: .::: ::::.:::::: :.:..::::::::::::
XP_016 VRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEH
380 390 400 410 420 430
390 400 410 420 430
pF1KB4 H---------LFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKL
. ::: ::::: ..::::::::::::. :. ::.: ::.::.::::::: .
XP_016 QCQHTLPTPSLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDI
440 450 460 470 480 490
440
pF1KB4 WLDAYLHK
:::::::.
XP_016 WLDAYLHQ
500
>>XP_011543324 (OMIM: 606148) PREDICTED: fatty acid desa (430 aa)
initn: 1836 init1: 1030 opt: 1753 Z-score: 2310.1 bits: 436.6 E(85289): 6.2e-122
Smith-Waterman score: 1753; 64.8% identity (84.4% similar) in 378 aa overlap (70-444:55-430)
40 50 60 70 80 90
pF1KB4 DRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEP
: : ::: . .: :... ::::::.::.:
XP_011 PTRRITYRARGCRTCQRESYRHGPYLAQPKDPFVAFHINKGLVKKYMNSLLIGELSPEQP
30 40 50 60 70 80
100 110 120 130 140 150
pF1KB4 SQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWI
: . ::...:..:: :: :.: :.:.:.::::::: : ::. :.. ::.:.. ::....
XP_011 SFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFL
90 100 110 120 130 140
160 170 180 190 200 210
pF1KB4 PTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ
: :. : .:.. ::::::::::.:::::. :::::.:.::::::::: :.:::: :::
XP_011 PFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQ
150 160 170 180 190 200
220 230 240 250 260 270
pF1KB4 HHAKPNIFHKDPDVNMLH--VFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPM
:::::: :.::::.:: : :.::. .: ::.: ::.::::::.:::::::: :.:.
XP_011 HHAKPNCFRKDPDINM-HPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALLPL
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB4 YFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFI-RFLESHWFVW
:::. :.. .: .:.:::::: ...:.:::.::.:. : : :.: : :: :::::.::::
XP_011 YFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLG-LKAFLGLFFIVRFLESNWFVW
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB4 VTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNL
::::::: :.::.. :: :.:: :::::..: :::::::::::::::::::::::::
XP_011 VTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNY
330 340 350 360 370 380
400 410 420 430 440
pF1KB4 HKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
::.::::.::::::::::: :::: :. :::.:::.::.::::::::.
XP_011 HKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ
390 400 410 420 430
>>NP_683725 (OMIM: 250790,613218) cytochrome b5 isoform (134 aa)
initn: 224 init1: 185 opt: 210 Z-score: 282.2 bits: 59.7 E(85289): 5.6e-09
Smith-Waterman score: 210; 35.6% identity (68.3% similar) in 101 aa overlap (11-110:2-101)
10 20 30 40 50 60
pF1KB4 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
: . . .: .. ::::::: . ::.. .:::..::. .::::..:.
NP_683 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVL
10 20 30 40 50
70 80 90 100 110
pF1KB4 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEE-PSQDHGKNSKITEDFRALRKT
. :: :::. :. . . . .. : ..:::: :.. :. .. .. ::
NP_683 REQAGGDATENFEDVGHSTD-AREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 AEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQ
NP_683 TNWVIPAISAVAVALMYRLYMAED
120 130
444 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:01:41 2016 done: Sat Nov 5 06:01:42 2016
Total Scan time: 8.100 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]