FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4712, 247 aa 1>>>pF1KB4712 247 - 247 aa - 247 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7743+/-0.00102; mu= 12.2309+/- 0.061 mean_var=75.0864+/-14.858, 0's: 0 Z-trim(103.4): 33 B-trim: 53 in 1/49 Lambda= 0.148011 statistics sampled from 7381 (7396) to 7381 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.227), width: 16 Scan time: 2.160 The best scores are: opt bits E(32554) CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 ( 247) 1582 347.3 5.7e-96 CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 ( 246) 1387 305.6 2e-83 CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 ( 246) 1164 258.0 4.2e-69 CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 ( 245) 1153 255.7 2.1e-68 CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 ( 245) 1091 242.4 2.1e-64 CCDS288.1 SFN gene_id:2810|Hs108|chr1 ( 248) 1031 229.6 1.5e-60 CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 ( 255) 1003 223.6 9.7e-59 >>CCDS5584.1 YWHAG gene_id:7532|Hs108|chr7 (247 aa) initn: 1582 init1: 1582 opt: 1582 Z-score: 1836.4 bits: 347.3 E(32554): 5.7e-96 Smith-Waterman score: 1582; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247) 10 20 30 40 50 60 pF1KB4 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD 190 200 210 220 230 240 pF1KB4 DGGEGNN ::::::: CCDS55 DGGEGNN >>CCDS13901.1 YWHAH gene_id:7533|Hs108|chr22 (246 aa) initn: 1387 init1: 1387 opt: 1387 Z-score: 1611.4 bits: 305.6 E(32554): 2e-83 Smith-Waterman score: 1387; 87.0% identity (95.9% similar) in 246 aa overlap (1-246:1-246) 10 20 30 40 50 60 pF1KB4 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW : :::::.:.::::::::::::::.::: :::::::::::.::::::::::::::::::: CCDS13 MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK :::::::::: :::::::.: :.:::::::::::.::.:::::::..:::::.. ::::: CCDS13 RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS ::::::::::::::::::.:::. .:::.:: ::.:: :::::.::::::::::::::.: CCDS13 VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD :::::::::::::: ::: ::::::::::::::::::::::::::::::::::::::::. CCDS13 VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE 190 200 210 220 230 240 pF1KB4 DGGEGNN ..:::: CCDS13 EAGEGN >>CCDS13339.1 YWHAB gene_id:7529|Hs108|chr20 (246 aa) initn: 1021 init1: 669 opt: 1164 Z-score: 1354.1 bits: 258.0 E(32554): 4.2e-69 Smith-Waterman score: 1164; 75.4% identity (89.5% similar) in 248 aa overlap (2-247:3-246) 10 20 30 40 50 pF1KB4 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSS .:. .:::::.:::::::::::::::: ::: .. ::::::::::::::::::::::: CCDS13 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 WRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYES ::::::::::: . :::: .: . :::::: ::. .:.::: :::.::: : :: :: CCDS13 WRVISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNA--TQPES 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 KVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNY :::::::::::.:::.:::.:... :.: .:..::.:: ::::..::::::::::::::. CCDS13 KVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 SVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQD ::::::: :.::.:: :::::::.::::::::::.:::::::::::::::::::::..: CCDS13 SVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQG 180 190 200 210 220 230 240 pF1KB4 DDG--GEGNN :.: :::.: CCDS13 DEGDAGEGEN 240 >>CCDS6290.1 YWHAZ gene_id:7534|Hs108|chr8 (245 aa) initn: 998 init1: 653 opt: 1153 Z-score: 1341.4 bits: 255.7 E(32554): 2.1e-68 Smith-Waterman score: 1153; 74.8% identity (89.4% similar) in 246 aa overlap (2-245:1-242) 10 20 30 40 50 60 pF1KB4 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW .:...:::::.::::::::::::: ::.::: . :::::::::::::::::::::::: CCDS62 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSW 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK ::.::::::: .: ::: .:.: :::::: ::. .:.::::::...:: : : : ::: CCDS62 RVVSSIEQKT--EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAS--QAESK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS ::::::::::::::::::.:. . .:..:..::.:: ::::..::::::::::::::.: CCDS62 VFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD :::::: :.::.:: :::::::.::::::::.:.:::::::::::::::::::::: : : CCDS62 VFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGD 180 190 200 210 220 230 pF1KB4 DG--GEGNN .. ::: CCDS62 EAEAGEGGEN 240 >>CCDS1666.1 YWHAQ gene_id:10971|Hs108|chr2 (245 aa) initn: 951 init1: 629 opt: 1091 Z-score: 1269.8 bits: 242.4 E(32554): 2.1e-64 Smith-Waterman score: 1091; 70.3% identity (87.0% similar) in 246 aa overlap (2-245:1-242) 10 20 30 40 50 60 pF1KB4 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW ... .:.:::.::::::::::::. :: ::: . ::::::::::::::::::.:::.: CCDS16 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAW 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK :::::::::: : ..::..... ::::.:.::...: :: :::.::: : :. ::: CCDS16 RVISSIEQKT--DTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIAN--ATNPESK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS ::::::::::.::::::: :. : ....:. ::.:: .:::..::::::::::::::.: CCDS16 VFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD :::::: : :: :: :::::::.:::::::::::::::::::::::::::::::::. . CCDS16 VFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGE 180 190 200 210 220 230 pF1KB4 --DGGEGNN :..:: CCDS16 ECDAAEGAEN 240 >>CCDS288.1 SFN gene_id:2810|Hs108|chr1 (248 aa) initn: 597 init1: 597 opt: 1031 Z-score: 1200.5 bits: 229.6 E(32554): 1.5e-60 Smith-Waterman score: 1031; 65.4% identity (89.3% similar) in 243 aa overlap (2-244:1-241) 10 20 30 40 50 60 pF1KB4 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW ..: .:.:::.::::::::.:::: ::...: .: :: :::::::::::::::..:..: CCDS28 MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAW 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK ::.::::::.. .:.:.: :: ::::.: ::..::. ::.:::..:::. ... ::. CCDS28 RVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDA--ESR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS ::::::::::::::::::::. . ...:...::.:: .:::..: ::.:::::::::.: CCDS28 VFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD ::.::: :.::.: ::::.::.:.:.: ::.::::::::::::::::::::::.:. . CCDS28 VFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGE 180 190 200 210 220 230 pF1KB4 DGGEGNN .::: CCDS28 EGGEAPQEPQS 240 >>CCDS11001.1 YWHAE gene_id:7531|Hs108|chr17 (255 aa) initn: 1024 init1: 584 opt: 1003 Z-score: 1168.0 bits: 223.6 E(32554): 9.7e-59 Smith-Waterman score: 1003; 64.2% identity (83.3% similar) in 246 aa overlap (1-246:1-243) 10 20 30 40 50 60 pF1KB4 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW : :::.:: .:.:::::::::.:. .::.:. .. :. :::::::::::::.::::.:: CCDS11 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK :.::::::: :.: :..:.: ::. .: ::. .: :.:..::..:: . ::: CCDS11 RIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTG--ESK 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS ::: ::::::.::::: :::. : ..:.: ::. : .:. .. ::::::::::::.: CCDS11 VFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD :::::: :.:..::.:::.::::::::::::.:.::::::::::::::::::::::.: : CCDS11 VFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD 180 190 200 210 220 230 pF1KB4 DGGEGNN : : : CCDS11 -GEEQNKEALQDVEDENQ 240 250 247 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:26:48 2016 done: Thu Nov 3 15:26:49 2016 Total Scan time: 2.160 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]