FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4718, 211 aa 1>>>pF1KB4718 211 - 211 aa - 211 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3177+/-0.000792; mu= 13.1161+/- 0.048 mean_var=62.4779+/-12.546, 0's: 0 Z-trim(108.1): 19 B-trim: 288 in 1/49 Lambda= 0.162260 statistics sampled from 10017 (10023) to 10017 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.308), width: 16 Scan time: 1.870 The best scores are: opt bits E(32554) CCDS13911.1 TIMP3 gene_id:7078|Hs108|chr22 ( 211) 1527 365.7 1.2e-101 CCDS2608.1 TIMP4 gene_id:7079|Hs108|chr3 ( 224) 706 173.5 8.9e-44 CCDS11758.1 TIMP2 gene_id:7077|Hs108|chr17 ( 220) 686 168.8 2.3e-42 CCDS14281.1 TIMP1 gene_id:7076|Hs108|chrX ( 207) 528 131.8 2.9e-31 >>CCDS13911.1 TIMP3 gene_id:7078|Hs108|chr22 (211 aa) initn: 1527 init1: 1527 opt: 1527 Z-score: 1938.4 bits: 365.7 E(32554): 1.2e-101 Smith-Waterman score: 1527; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211) 10 20 30 40 50 60 pF1KB4 MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSK 130 140 150 160 170 180 190 200 210 pF1KB4 HYACIRQKGGYCSWYRGWAPPDKSIINATDP ::::::::::::::::::::::::::::::: CCDS13 HYACIRQKGGYCSWYRGWAPPDKSIINATDP 190 200 210 >>CCDS2608.1 TIMP4 gene_id:7079|Hs108|chr3 (224 aa) initn: 688 init1: 392 opt: 706 Z-score: 899.4 bits: 173.5 E(32554): 8.9e-44 Smith-Waterman score: 706; 47.4% identity (73.5% similar) in 215 aa overlap (4-211:11-224) 10 20 30 40 50 pF1KB4 MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVK :. :. ::. : :::.:.:.:::. .:.: .:::::. ..:.: CCDS26 MPGSPRPAPSWVLLLRLLALLRPPGLG-EACSCAPAHPQQHICHSALVIRAKISSEKVVP 10 20 30 40 50 60 70 80 90 100 pF1KB4 EG--PFGT---LVYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVN-KYQYLLTGR . : : : : :::.::..:: :. ::::.: . ::::.:::.: . ::::::. CCDS26 ASADPADTEKMLRYEIKQIKMFKGFEKVKDVQYIYTPFDSSLCGVKLEANSQKQYLLTGQ 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 VY-DGKMYTGLCNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWT : :::.. :::..: :..:.: ::..::..:::.:.:.: .:: .:: ... :::::: CCDS26 VLSDGKVFIHLCNYIEPWEDLSLVQRESLNHHYHLNCGCQITTCYTVPCTISAPNECLWT 120 130 140 150 160 170 170 180 190 200 210 pF1KB4 DMLSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP : : . :::..::.:... : :::::: : : ... ..: CCDS26 DWLLERKLYGYQAQHYVCMKHVDGTCSWYRGHLPLRKEFVDIVQP 180 190 200 210 220 >>CCDS11758.1 TIMP2 gene_id:7077|Hs108|chr17 (220 aa) initn: 616 init1: 456 opt: 686 Z-score: 874.2 bits: 168.8 E(32554): 2.3e-42 Smith-Waterman score: 686; 45.2% identity (75.4% similar) in 199 aa overlap (21-211:24-220) 10 20 30 40 50 pF1KB4 MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEG-- :.::.::: :::.::::.:.:::::.:..: : : CCDS11 MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGND 10 20 30 40 50 60 60 70 80 90 100 pF1KB4 ----PFGTLVYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVN-KYQYLLTGRVY- :. . : :::.::..: : ...:.: : ..::..:.:. : .::..:.. CCDS11 IYGNPIKRIQYEIKQIKMFKGPEK--DIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEG 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 DGKMYTGLCNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDML ::::. ::.:. :: :. .:.:.::.::..::.::: : ..::...: .:::: : . CCDS11 DGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWV 120 130 140 150 160 170 170 180 190 200 210 pF1KB4 SNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP .. . :.:.: .:::... : :.:::: ::: . ... :: CCDS11 TEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP 180 190 200 210 220 >>CCDS14281.1 TIMP1 gene_id:7076|Hs108|chrX (207 aa) initn: 512 init1: 160 opt: 528 Z-score: 674.7 bits: 131.8 E(32554): 2.9e-31 Smith-Waterman score: 528; 38.6% identity (65.8% similar) in 202 aa overlap (1-194:1-199) 10 20 30 40 50 pF1KB4 MTPWLGLI--VLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFG :.:. : .:: : .. ..:::: : ::: ::::::.::::: :: :.. . CCDS14 MAPFEPLASGILLLLWLIAP--SRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLY 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 TLVYTIKQMKMYRGFTKM---PHVQYIHTEASESLCGL--KLEVNKYQYLLTGRVYDGKM : ::. :::.:: . .....: : ::.:: . . . ..:..:.. :: . CCDS14 QR-YEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 YTGLCNFVERWDQLTLSQRKGLNYRYHLGCN-CKIKSCYYLPCFVTSKNECLWTDMLSNF . :.:: :..:.:.::.:.. : .::. : . : .:: . : ..:::::.: . CCDS14 HITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQG 120 130 140 150 160 170 180 190 200 210 pF1KB4 GYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP . :.::.: ::. .. : :.: CCDS14 SEKGFQSRHLACLPREPGLCTWQSLRSQIA 180 190 200 211 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:11:35 2016 done: Fri Nov 4 03:11:35 2016 Total Scan time: 1.870 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]