Result of FASTA (omim) for
pF1KB4722
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4722, 330 aa
1>>>pF1KB4722 330 - 330 aa - 330 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5202+/-0.000595; mu= 10.0636+/- 0.036
mean_var=211.6081+/-43.162, 0's: 0 Z-trim(111.3): 551 B-trim: 78 in 1/48
Lambda= 0.088167
statistics sampled from 19166 (19873) to 19166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.588), E-opt: 0.2 (0.233), width: 16
Scan time: 6.520
The best scores are: opt bits E(85289)
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 1919 257.7 2.5e-68
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 1919 257.7 2.5e-68
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 1919 257.7 2.5e-68
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 537 81.9 2.1e-15
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 537 81.9 2.2e-15
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 537 82.0 2.2e-15
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 537 82.0 2.3e-15
NP_001093207 (OMIM: 616850) WD repeat domain-conta ( 315) 532 81.2 3.2e-15
NP_115708 (OMIM: 616850) WD repeat domain-containi ( 315) 532 81.2 3.2e-15
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 522 80.0 7.8e-15
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 519 79.5 9.6e-15
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 515 79.2 1.6e-14
NP_001188493 (OMIM: 605961) pleiotropic regulator ( 505) 486 75.7 2.4e-13
NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 486 75.7 2.4e-13
XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 476 74.1 4.5e-13
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 476 74.1 4.5e-13
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 476 74.1 4.5e-13
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 476 74.1 4.5e-13
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 476 74.2 5e-13
XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 476 74.4 5.8e-13
XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 476 74.4 5.8e-13
XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 476 74.4 5.9e-13
XP_011510125 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 476 74.4 5.9e-13
XP_011510123 (OMIM: 612173) PREDICTED: sperm-assoc ( 537) 476 74.4 6e-13
XP_011510121 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 476 74.5 6.2e-13
XP_011510116 (OMIM: 612173) PREDICTED: sperm-assoc ( 600) 476 74.5 6.4e-13
NP_078808 (OMIM: 612173) sperm-associated antigen ( 631) 476 74.5 6.6e-13
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 444 70.1 7.8e-12
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 444 70.2 8.6e-12
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 444 70.2 8.6e-12
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 444 70.2 8.6e-12
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 444 70.2 8.6e-12
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 444 70.2 8.8e-12
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 444 70.2 8.8e-12
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 444 70.2 8.8e-12
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 441 70.0 1.3e-11
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 441 70.0 1.4e-11
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 441 70.1 1.4e-11
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 441 70.1 1.5e-11
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 441 70.1 1.5e-11
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 441 70.1 1.5e-11
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 441 70.1 1.5e-11
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 441 70.1 1.5e-11
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 441 70.1 1.5e-11
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 441 70.1 1.5e-11
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 427 67.8 3.1e-11
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 427 67.8 3.1e-11
XP_011510120 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 429 68.5 3.9e-11
XP_011510119 (OMIM: 612173) PREDICTED: sperm-assoc ( 582) 429 68.5 3.9e-11
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 425 67.6 4e-11
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 2379 init1: 1903 opt: 1919 Z-score: 1347.6 bits: 257.7 E(85289): 2.5e-68
Smith-Waterman score: 1919; 85.3% identity (94.3% similar) in 333 aa overlap (1-329:1-333)
10 20 30 40 50
pF1KB4 MATKESRD----AKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWL
:::.:.. :.:: . ::::.::: .: .:::::: ::.:::.::::::::::::::
NP_060 MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 ASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGK
::::::.:: ::::::::.:::. ::.: ::::::::::. :::::::::::.::: :::
NP_060 ASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 CLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN
::::::::::::::::::: ::::.::::::.:.::.:::::::::: ::::::::::::
NP_060 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 CSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKL
.::::::.::::::::::.:::::::::.::::::::::::::::::::.:::::::::
NP_060 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 WDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH
::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH
250 260 270 280 290 300
300 310 320 330
pF1KB4 TDVVISAACHPTENLIASAALENDKTIKLWMSNH
::::::.:::::::.::::::::::::::: :.
NP_060 TDVVISTACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 2379 init1: 1903 opt: 1919 Z-score: 1347.6 bits: 257.7 E(85289): 2.5e-68
Smith-Waterman score: 1919; 85.3% identity (94.3% similar) in 333 aa overlap (1-329:1-333)
10 20 30 40 50
pF1KB4 MATKESRD----AKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWL
:::.:.. :.:: . ::::.::: .: .:::::: ::.:::.::::::::::::::
NP_438 MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 ASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGK
::::::.:: ::::::::.:::. ::.: ::::::::::. :::::::::::.::: :::
NP_438 ASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 CLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN
::::::::::::::::::: ::::.::::::.:.::.:::::::::: ::::::::::::
NP_438 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 CSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKL
.::::::.::::::::::.:::::::::.::::::::::::::::::::.:::::::::
NP_438 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 WDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH
::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_438 WDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH
250 260 270 280 290 300
300 310 320 330
pF1KB4 TDVVISAACHPTENLIASAALENDKTIKLWMSNH
::::::.:::::::.::::::::::::::: :.
NP_438 TDVVISTACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 2379 init1: 1903 opt: 1919 Z-score: 1347.6 bits: 257.7 E(85289): 2.5e-68
Smith-Waterman score: 1919; 85.3% identity (94.3% similar) in 333 aa overlap (1-329:1-333)
10 20 30 40 50
pF1KB4 MATKESRD----AKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWL
:::.:.. :.:: . ::::.::: .: .:::::: ::.:::.::::::::::::::
XP_005 MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 ASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGK
::::::.:: ::::::::.:::. ::.: ::::::::::. :::::::::::.::: :::
XP_005 ASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 CLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN
::::::::::::::::::: ::::.::::::.:.::.:::::::::: ::::::::::::
XP_005 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 CSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKL
.::::::.::::::::::.:::::::::.::::::::::::::::::::.:::::::::
XP_005 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 WDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH
::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH
250 260 270 280 290 300
300 310 320 330
pF1KB4 TDVVISAACHPTENLIASAALENDKTIKLWMSNH
::::::.:::::::.::::::::::::::: :.
XP_005 TDVVISTACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 cen (321 aa)
initn: 752 init1: 390 opt: 537 Z-score: 397.7 bits: 81.9 E(85289): 2.1e-15
Smith-Waterman score: 537; 36.0% identity (70.4% similar) in 247 aa overlap (37-282:19-260)
10 20 30 40 50 60
pF1KB4 RDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLII
..:: .::. :.:::.:. :::.: :. .
XP_016 MDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR
10 20 30 40
70 80 90 100 110 120
pF1KB4 IWGAYDGKYEKTLY-GHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHS
:: . . : :.:.. .:. . .: . ::.. .:.::::::.:.: .. : : .:. :
XP_016 IW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSG
:.: : .:.: . ::.:.: :.:::.:. .. .:... :. :. : :. ::. :...
XP_016 NWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB4 SYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL
..:. ..::. . . :. . . :. ..: :.:.:..::. :.:::. : .:: :
XP_016 GMDNTVKVWDVRTHRLLQHY-QLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB4 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC
: ::.. . :: :: ....::. :. :..:
XP_016 YTLHGHQGPATTV--AFSRTG-EYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLA
230 240 250 260 270 280
310 320 330
pF1KB4 HPTENLIASAALENDKTIKLWMSNH
XP_016 SSMGNLTVSILEQRLTLTEDKLKQCLENQQLIMQRATP
290 300 310 320
>>NP_001155052 (OMIM: 614783,614813) POC1 centriolar pro (359 aa)
initn: 918 init1: 390 opt: 537 Z-score: 397.2 bits: 81.9 E(85289): 2.2e-15
Smith-Waterman score: 537; 36.0% identity (70.4% similar) in 247 aa overlap (37-282:57-298)
10 20 30 40 50 60
pF1KB4 RDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLII
..:: .::. :.:::.:. :::.: :. .
NP_001 FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB4 IWGAYDGKYEKTLY-GHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHS
:: . . : :.:.. .:. . .: . ::.. .:.::::::.:.: .. : : .:. :
NP_001 IW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHI
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB4 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSG
:.: : .:.: . ::.:.: :.:::.:. .. .:... :. :. : :. ::. :...
NP_001 NWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAA
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB4 SYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL
..:. ..::. . . :. . . :. ..: :.:.:..::. :.:::. : .:: :
NP_001 GMDNTVKVWDVRTHRLLQHY-QLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLL
210 220 230 240 250 260
250 260 270 280 290 300
pF1KB4 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC
: ::.. . :: :: ....::. :. :..:
NP_001 YTLHGHQGPATTV--AFSRTG-EYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLA
270 280 290 300 310 320
310 320 330
pF1KB4 HPTENLIASAALENDKTIKLWMSNH
NP_001 SSMGNLTVSILEQRLTLTEDKLKQCLENQQLIMQRATP
330 340 350
>>NP_001155053 (OMIM: 614783,614813) POC1 centriolar pro (369 aa)
initn: 752 init1: 390 opt: 537 Z-score: 397.1 bits: 82.0 E(85289): 2.2e-15
Smith-Waterman score: 537; 36.0% identity (70.4% similar) in 247 aa overlap (37-282:19-260)
10 20 30 40 50 60
pF1KB4 RDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLII
..:: .::. :.:::.:. :::.: :. .
NP_001 MDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR
10 20 30 40
70 80 90 100 110 120
pF1KB4 IWGAYDGKYEKTLY-GHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHS
:: . . : :.:.. .:. . .: . ::.. .:.::::::.:.: .. : : .:. :
NP_001 IW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSG
:.: : .:.: . ::.:.: :.:::.:. .. .:... :. :. : :. ::. :...
NP_001 NWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB4 SYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL
..:. ..::. . . :. . . :. ..: :.:.:..::. :.:::. : .:: :
NP_001 GMDNTVKVWDVRTHRLLQHY-QLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB4 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC
: ::.. . :: :: ....::. :. :..:
NP_001 YTLHGHQGPATTV--AFSRTG-EYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLA
230 240 250 260 270 280
310 320 330
pF1KB4 HPTENLIASAALENDKTIKLWMSNH
NP_001 SSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLTSTLEHIVGQLDVLTQTVSILE
290 300 310 320 330 340
>>NP_056241 (OMIM: 614783,614813) POC1 centriolar protei (407 aa)
initn: 918 init1: 390 opt: 537 Z-score: 396.7 bits: 82.0 E(85289): 2.3e-15
Smith-Waterman score: 537; 36.0% identity (70.4% similar) in 247 aa overlap (37-282:57-298)
10 20 30 40 50 60
pF1KB4 RDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLII
..:: .::. :.:::.:. :::.: :. .
NP_056 FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB4 IWGAYDGKYEKTLY-GHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHS
:: . . : :.:.. .:. . .: . ::.. .:.::::::.:.: .. : : .:. :
NP_056 IW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHI
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB4 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSG
:.: : .:.: . ::.:.: :.:::.:. .. .:... :. :. : :. ::. :...
NP_056 NWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAA
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB4 SYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL
..:. ..::. . . :. . . :. ..: :.:.:..::. :.:::. : .:: :
NP_056 GMDNTVKVWDVRTHRLLQHY-QLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLL
210 220 230 240 250 260
250 260 270 280 290 300
pF1KB4 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC
: ::.. . :: :: ....::. :. :..:
NP_056 YTLHGHQGPATTV--AFSRTG-EYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLA
270 280 290 300 310 320
310 320 330
pF1KB4 HPTENLIASAALENDKTIKLWMSNH
NP_056 SSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSVPQTLTSTLEHIVGQLDVLTQTVSILE
330 340 350 360 370 380
>>NP_001093207 (OMIM: 616850) WD repeat domain-containin (315 aa)
initn: 638 init1: 241 opt: 532 Z-score: 394.4 bits: 81.2 E(85289): 3.2e-15
Smith-Waterman score: 532; 33.0% identity (61.1% similar) in 303 aa overlap (26-326:11-303)
10 20 30 40 50 60
pF1KB4 MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSS
:: :. :: :. :: .:.:. .:.. . .
NP_001 MAFPEPKPRPPELPQKRLKTLDCGQG-AVRAVRFNVDGNYCLTCG
10 20 30 40
70 80 90 100 110 120
pF1KB4 ADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKT
.:. . .:. : .: ::. :. :.: : :.: : :.. ::.. :::: ::. ..
NP_001 SDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRK
50 60 70 80 90 100
130 140 150 160 170
pF1KB4 LKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKC--LKTLSAHSDPVSAVHFNCS
..::.. : .:: ...:.:::.: ... :. .. . ..::. : ::.:. :
NP_001 FRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKV--S
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 GSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWD
:..:: :: : .: :: .. : . :.. . :: .:. :...::.::.: :
NP_001 DHEILAGSVDGRVRRYDLRMGQLFSDYVGS---PITCTCFSRDGQCTLVSSLDSTLRLLD
170 180 190 200 210
240 250 260 270 280 290
pF1KB4 YSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD
. :. : : ::::..: . .: . .:: :::. :..:.: .. : .
NP_001 KDTGELLGEYKGHKNQEYKLDCCLSERDTH-VVSCSEDGKVFFWDLVEGALALALPVGSG
220 230 240 250 260 270
300 310 320 330
pF1KB4 VVISAACHPTENLIASAALENDKTIKLWMSNH
:: : : :::: . .: ... :
NP_001 VVQSLAYHPTEPCLLTAM---GGSVQCWREEAYEAEDGAG
280 290 300 310
>>NP_115708 (OMIM: 616850) WD repeat domain-containing p (315 aa)
initn: 638 init1: 241 opt: 532 Z-score: 394.4 bits: 81.2 E(85289): 3.2e-15
Smith-Waterman score: 532; 33.0% identity (61.1% similar) in 303 aa overlap (26-326:11-303)
10 20 30 40 50 60
pF1KB4 MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSS
:: :. :: :. :: .:.:. .:.. . .
NP_115 MAFPEPKPRPPELPQKRLKTLDCGQG-AVRAVRFNVDGNYCLTCG
10 20 30 40
70 80 90 100 110 120
pF1KB4 ADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKT
.:. . .:. : .: ::. :. :.: : :.: : :.. ::.. :::: ::. ..
NP_115 SDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRK
50 60 70 80 90 100
130 140 150 160 170
pF1KB4 LKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKC--LKTLSAHSDPVSAVHFNCS
..::.. : .:: ...:.:::.: ... :. .. . ..::. : ::.:. :
NP_115 FRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKV--S
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 GSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWD
:..:: :: : .: :: .. : . :.. . :: .:. :...::.::.: :
NP_115 DHEILAGSVDGRVRRYDLRMGQLFSDYVGS---PITCTCFSRDGQCTLVSSLDSTLRLLD
170 180 190 200 210
240 250 260 270 280 290
pF1KB4 YSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTD
. :. : : ::::..: . .: . .:: :::. :..:.: .. : .
NP_115 KDTGELLGEYKGHKNQEYKLDCCLSERDTH-VVSCSEDGKVFFWDLVEGALALALPVGSG
220 230 240 250 260 270
300 310 320 330
pF1KB4 VVISAACHPTENLIASAALENDKTIKLWMSNH
:: : : :::: . .: ... :
NP_115 VVQSLAYHPTEPCLLTAM---GGSVQCWREEAYEAEDGAG
280 290 300 310
>>XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 cen (326 aa)
initn: 918 init1: 390 opt: 522 Z-score: 387.3 bits: 80.0 E(85289): 7.8e-15
Smith-Waterman score: 522; 34.7% identity (68.0% similar) in 259 aa overlap (37-294:57-311)
10 20 30 40 50 60
pF1KB4 RDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLII
..:: .::. :.:::.:. :::.: :. .
XP_011 FSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVR
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB4 IWGAYDGKYEKTLY-GHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHS
:: . . : :.:.. .:. . .: . ::.. .:.::::::.:.: .. : : .:. :
XP_011 IW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHI
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB4 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSG
:.: : .:.: . ::.:.: :.:::.:. .. .:... :. :. : :. ::. :...
XP_011 NWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAA
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB4 SYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCL
..:. ..::. . . :. . . :. ..: :.:.:..::. :.:::. : .:: :
XP_011 GMDNTVKVWDVRTHRLLQHY-QLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLL
210 220 230 240 250 260
250 260 270 280 290 300
pF1KB4 KTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC
: ::.. . :: :: . .::... : : . . .::.
XP_011 YTLHGHQGPATTV--AFSRTGEYFASGGSDEQTVSILEQRLTLTEDKLKQCLENQQLIMQ
270 280 290 300 310 320
310 320 330
pF1KB4 HPTENLIASAALENDKTIKLWMSNH
XP_011 RATP
330 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:02:14 2016 done: Sat Nov 5 06:02:16 2016
Total Scan time: 6.520 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]