FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4753, 108 aa 1>>>pF1KB4753 108 - 108 aa - 108 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1073+/-0.00027; mu= 11.3817+/- 0.017 mean_var=70.3216+/-14.428, 0's: 0 Z-trim(120.2): 29 B-trim: 0 in 0/56 Lambda= 0.152943 statistics sampled from 35153 (35184) to 35153 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.413), width: 16 Scan time: 4.400 The best scores are: opt bits E(85289) NP_057394 (OMIM: 606007) DNA-directed RNA polymera ( 108) 805 185.5 1.5e-47 NP_006224 (OMIM: 180662) DNA-directed RNA polymera ( 125) 190 49.8 1.2e-06 XP_016857692 (OMIM: 604128) PREDICTED: transcripti ( 450) 166 44.9 0.00013 XP_016857690 (OMIM: 604128) PREDICTED: transcripti ( 466) 166 44.9 0.00013 XP_016857691 (OMIM: 604128) PREDICTED: transcripti ( 466) 166 44.9 0.00013 XP_016857689 (OMIM: 604128) PREDICTED: transcripti ( 487) 166 44.9 0.00013 XP_006716530 (OMIM: 601425) PREDICTED: transcripti ( 254) 160 43.4 0.0002 XP_011515880 (OMIM: 601425) PREDICTED: transcripti ( 266) 160 43.4 0.00021 NP_958845 (OMIM: 601425) transcription elongation ( 280) 160 43.4 0.00022 NP_006747 (OMIM: 601425) transcription elongation ( 301) 160 43.5 0.00023 XP_016857693 (OMIM: 604128) PREDICTED: transcripti ( 327) 158 43.0 0.00033 NP_003187 (OMIM: 604128) transcription elongation ( 348) 158 43.1 0.00035 XP_006710927 (OMIM: 604128) PREDICTED: transcripti ( 351) 158 43.1 0.00035 XP_011540355 (OMIM: 604128) PREDICTED: transcripti ( 364) 158 43.1 0.00036 NP_942016 (OMIM: 604784) transcription elongation ( 272) 155 42.3 0.00045 XP_016883525 (OMIM: 604784) PREDICTED: transcripti ( 272) 155 42.3 0.00045 XP_016883526 (OMIM: 604784) PREDICTED: transcripti ( 272) 155 42.3 0.00045 XP_011527325 (OMIM: 604784) PREDICTED: transcripti ( 297) 155 42.4 0.00049 XP_011527329 (OMIM: 604784) PREDICTED: transcripti ( 297) 155 42.4 0.00049 XP_011527324 (OMIM: 604784) PREDICTED: transcripti ( 297) 155 42.4 0.00049 NP_003186 (OMIM: 604784) transcription elongation ( 299) 155 42.4 0.00049 XP_005260286 (OMIM: 604784) PREDICTED: transcripti ( 324) 155 42.4 0.00052 NP_001265714 (OMIM: 607525) DNA-directed RNA polym ( 126) 137 38.1 0.0039 NP_055411 (OMIM: 607525) DNA-directed RNA polymera ( 126) 137 38.1 0.0039 NP_001265715 (OMIM: 607525) DNA-directed RNA polym ( 126) 137 38.1 0.0039 NP_740753 (OMIM: 607525) DNA-directed RNA polymera ( 126) 137 38.1 0.0039 >>NP_057394 (OMIM: 606007) DNA-directed RNA polymerase I (108 aa) initn: 805 init1: 805 opt: 805 Z-score: 974.8 bits: 185.5 E(85289): 1.5e-47 Smith-Waterman score: 805; 100.0% identity (100.0% similar) in 108 aa overlap (1-108:1-108) 10 20 30 40 50 60 pF1KB4 MLLFCPGCGNGLIVEEGQRCHRFACNTCPYVHNITRKVTNRKYPKLKEVDDVLGGAAAWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MLLFCPGCGNGLIVEEGQRCHRFACNTCPYVHNITRKVTNRKYPKLKEVDDVLGGAAAWE 10 20 30 40 50 60 70 80 90 100 pF1KB4 NVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKCCNAQCGHRWRD :::::::::::::::::::::::::::::::::::::::::::::::: NP_057 NVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKCCNAQCGHRWRD 70 80 90 100 >>NP_006224 (OMIM: 180662) DNA-directed RNA polymerase I (125 aa) initn: 193 init1: 128 opt: 190 Z-score: 240.5 bits: 49.8 E(85289): 1.2e-06 Smith-Waterman score: 190; 27.3% identity (55.5% similar) in 110 aa overlap (4-108:16-125) 10 20 30 40 pF1KB4 MLLFCPGCGNGLIVEEGQ--RCHRFACNTCPYVHNITRKV--TNRKYP :: :.: : .: . : .:: .: : .. . .:. NP_006 MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 KLKEVDDVLGGAAAWENVDSTAES-CPKCEHPRAYFMQLQTRSADEPMTTFYKCCNAQCG .. :. .... .. .. : . : :: : .: :.: .. :.. : .: : .:: NP_006 EVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCG 70 80 90 100 110 120 pF1KB4 HRWRD ::: . NP_006 HRWTE >>XP_016857692 (OMIM: 604128) PREDICTED: transcription e (450 aa) initn: 169 init1: 112 opt: 166 Z-score: 204.1 bits: 44.9 E(85289): 0.00013 Smith-Waterman score: 166; 55.0% identity (72.5% similar) in 40 aa overlap (69-108:273-310) 40 50 60 70 80 90 pF1KB4 TNRKYPKLKEVDDVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKCC : ::.. . :.:::::::::::: : XP_016 LRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLC- 250 260 270 280 290 300 100 pF1KB4 NAQCGHRWRD .::.::.: XP_016 -NECGNRWKDEQVCHLSTDGIGFLRSTEERKNILHLDHASLESASTDGISFEPGHSQGWE 310 320 330 340 350 360 >>XP_016857690 (OMIM: 604128) PREDICTED: transcription e (466 aa) initn: 169 init1: 112 opt: 166 Z-score: 203.9 bits: 44.9 E(85289): 0.00013 Smith-Waterman score: 166; 55.0% identity (72.5% similar) in 40 aa overlap (69-108:289-326) 40 50 60 70 80 90 pF1KB4 TNRKYPKLKEVDDVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKCC : ::.. . :.:::::::::::: : XP_016 LRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLC- 260 270 280 290 300 310 100 pF1KB4 NAQCGHRWRD .::.::.: XP_016 -NECGNRWKDEQVCHLSTDGIGFLRSTEERKNILHLDHASLESASTDGISFEPGHSQGWE 320 330 340 350 360 370 >>XP_016857691 (OMIM: 604128) PREDICTED: transcription e (466 aa) initn: 169 init1: 112 opt: 166 Z-score: 203.9 bits: 44.9 E(85289): 0.00013 Smith-Waterman score: 166; 55.0% identity (72.5% similar) in 40 aa overlap (69-108:289-326) 40 50 60 70 80 90 pF1KB4 TNRKYPKLKEVDDVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKCC : ::.. . :.:::::::::::: : XP_016 LRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLC- 260 270 280 290 300 310 100 pF1KB4 NAQCGHRWRD .::.::.: XP_016 -NECGNRWKDEQVCHLSTDGIGFLRSTEERKNILHLDHASLESASTDGISFEPGHSQGWE 320 330 340 350 360 370 >>XP_016857689 (OMIM: 604128) PREDICTED: transcription e (487 aa) initn: 169 init1: 112 opt: 166 Z-score: 203.6 bits: 44.9 E(85289): 0.00013 Smith-Waterman score: 166; 55.0% identity (72.5% similar) in 40 aa overlap (69-108:310-347) 40 50 60 70 80 90 pF1KB4 TNRKYPKLKEVDDVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKCC : ::.. . :.:::::::::::: : XP_016 LRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLC- 280 290 300 310 320 330 100 pF1KB4 NAQCGHRWRD .::.::.: XP_016 -NECGNRWKDEQVCHLSTDGIGFLRSTEERKNILHLDHASLESASTDGISFEPGHSQGWE 340 350 360 370 380 390 >>XP_006716530 (OMIM: 601425) PREDICTED: transcription e (254 aa) initn: 160 init1: 113 opt: 160 Z-score: 200.4 bits: 43.4 E(85289): 0.0002 Smith-Waterman score: 160; 52.5% identity (72.5% similar) in 40 aa overlap (68-107:215-252) 40 50 60 70 80 90 pF1KB4 VTNRKYPKLKEVDDVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKC .: ::.. . :.:::::::::::: : XP_006 ELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVC 190 200 210 220 230 240 100 pF1KB4 CNAQCGHRWRD .::.::. XP_006 --NECGNRWKFC 250 >>XP_011515880 (OMIM: 601425) PREDICTED: transcription e (266 aa) initn: 160 init1: 113 opt: 160 Z-score: 200.1 bits: 43.4 E(85289): 0.00021 Smith-Waterman score: 160; 52.5% identity (72.5% similar) in 40 aa overlap (68-107:227-264) 40 50 60 70 80 90 pF1KB4 VTNRKYPKLKEVDDVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKC .: ::.. . :.:::::::::::: : XP_011 ELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVC 200 210 220 230 240 250 100 pF1KB4 CNAQCGHRWRD .::.::. XP_011 --NECGNRWKFC 260 >>NP_958845 (OMIM: 601425) transcription elongation fact (280 aa) initn: 160 init1: 113 opt: 160 Z-score: 199.8 bits: 43.4 E(85289): 0.00022 Smith-Waterman score: 160; 52.5% identity (72.5% similar) in 40 aa overlap (68-107:241-278) 40 50 60 70 80 90 pF1KB4 VTNRKYPKLKEVDDVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKC .: ::.. . :.:::::::::::: : NP_958 ELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVC 220 230 240 250 260 270 100 pF1KB4 CNAQCGHRWRD .::.::. NP_958 --NECGNRWKFC 280 >>NP_006747 (OMIM: 601425) transcription elongation fact (301 aa) initn: 160 init1: 113 opt: 160 Z-score: 199.4 bits: 43.5 E(85289): 0.00023 Smith-Waterman score: 160; 52.5% identity (72.5% similar) in 40 aa overlap (68-107:262-299) 40 50 60 70 80 90 pF1KB4 VTNRKYPKLKEVDDVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKC .: ::.. . :.:::::::::::: : NP_006 ELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVC 240 250 260 270 280 290 100 pF1KB4 CNAQCGHRWRD .::.::. NP_006 --NECGNRWKFC 300 108 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:49:29 2016 done: Sat Nov 5 21:49:29 2016 Total Scan time: 4.400 Total Display time: -0.050 Function used was FASTA [36.3.4 Apr, 2011]