FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4784, 271 aa 1>>>pF1KB4784 271 - 271 aa - 271 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5984+/-0.000841; mu= 12.4594+/- 0.050 mean_var=58.5906+/-12.017, 0's: 0 Z-trim(105.1): 19 B-trim: 216 in 1/52 Lambda= 0.167556 statistics sampled from 8233 (8245) to 8233 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.253), width: 16 Scan time: 2.350 The best scores are: opt bits E(32554) CCDS41801.1 CTDSP2 gene_id:10106|Hs108|chr12 ( 271) 1806 445.0 2.7e-125 CCDS33734.1 CTDSPL gene_id:10217|Hs108|chr3 ( 276) 1083 270.2 1.1e-72 CCDS33735.1 CTDSPL gene_id:10217|Hs108|chr3 ( 265) 990 247.7 6.4e-66 CCDS2416.1 CTDSP1 gene_id:58190|Hs108|chr2 ( 261) 981 245.5 2.8e-65 CCDS56166.1 CTDSP1 gene_id:58190|Hs108|chr2 ( 260) 976 244.3 6.5e-65 CCDS10110.1 CTDSPL2 gene_id:51496|Hs108|chr15 ( 466) 509 131.5 1.1e-30 CCDS11093.1 CTDNEP1 gene_id:23399|Hs108|chr17 ( 244) 415 108.7 4.1e-24 CCDS33023.1 TIMM50 gene_id:92609|Hs108|chr19 ( 456) 240 66.4 4e-11 >>CCDS41801.1 CTDSP2 gene_id:10106|Hs108|chr12 (271 aa) initn: 1806 init1: 1806 opt: 1806 Z-score: 2362.9 bits: 445.0 E(32554): 2.7e-125 Smith-Waterman score: 1806; 100.0% identity (100.0% similar) in 271 aa overlap (1-271:1-271) 10 20 30 40 50 60 pF1KB4 MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 AYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 NNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDM 190 200 210 220 230 240 250 260 270 pF1KB4 ADTELLNLIPIFEELSGAEDVYTSLGQLRAP ::::::::::::::::::::::::::::::: CCDS41 ADTELLNLIPIFEELSGAEDVYTSLGQLRAP 250 260 270 >>CCDS33734.1 CTDSPL gene_id:10217|Hs108|chr3 (276 aa) initn: 1093 init1: 1033 opt: 1083 Z-score: 1418.2 bits: 270.2 E(32554): 1.1e-72 Smith-Waterman score: 1083; 64.4% identity (78.9% similar) in 275 aa overlap (1-268:1-273) 10 20 30 40 50 pF1KB4 MEHGSIITQAR--REDALVLTKQGLVSKS---SPKKPRGRNIFKALFCCFRAQHV--GQS :. .::::. .:: : : ... : :: :.:.:....::::: .: CCDS33 MDGPAIITQVTNPKEDEGRLPGAGEKASQCNVSLKKQRSRSILSSFFCCFRDYNVEAPPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 SSSTELAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLV :: . : :: . . :.: : . . :. :::::: : :. ::::::::::: CCDS33 SSPSVLPPLVEENGGLQKGDQRQVIPIP--SPPAKYLLPEVTVLDYGKKCVVIDLDETLV 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 HSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPV :::::::.:::::::.::.:: :::::::::.:::::.:::.:::::::::::::::::: CCDS33 HSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 TDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPV .::::: :::::::::::::::.: ::::::::::.: :..:.::::::::::::::::: CCDS33 ADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPV 180 190 200 210 220 230 240 250 260 270 pF1KB4 QSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP :::::::.:::::.:::.:: :: .:::. : .: CCDS33 QSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCNR 240 250 260 270 >>CCDS33735.1 CTDSPL gene_id:10217|Hs108|chr3 (265 aa) initn: 1116 init1: 984 opt: 990 Z-score: 1297.0 bits: 247.7 E(32554): 6.4e-66 Smith-Waterman score: 1055; 63.6% identity (77.1% similar) in 275 aa overlap (1-268:1-262) 10 20 30 40 50 pF1KB4 MEHGSIITQAR--REDALVLTKQGLVSKS---SPKKPRGRNIFKALFCCFRAQHV--GQS :. .::::. .:: : : ... : :: :.:.:....::::: .: CCDS33 MDGPAIITQVTNPKEDEGRLPGAGEKASQCNVSLKKQRSRSILSSFFCCFRDYNVEAPPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 SSSTELAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLV :: . : :: . . : :. :::::: : :. ::::::::::: CCDS33 SSPSVLPPLVEENGGLQKP-------------PAKYLLPEVTVLDYGKKCVVIDLDETLV 70 80 90 100 120 130 140 150 160 170 pF1KB4 HSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPV :::::::.:::::::.::.:: :::::::::.:::::.:::.:::::::::::::::::: CCDS33 HSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPV 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 TDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPV .::::: :::::::::::::::.: ::::::::::.: :..:.::::::::::::::::: CCDS33 ADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPV 170 180 190 200 210 220 240 250 260 270 pF1KB4 QSWFDDMADTELLNLIPIFEELSGAEDVYTSLGQLRAP :::::::.:::::.:::.:: :: .:::. : .: CCDS33 QSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCNR 230 240 250 260 >>CCDS2416.1 CTDSP1 gene_id:58190|Hs108|chr2 (261 aa) initn: 1038 init1: 973 opt: 981 Z-score: 1285.3 bits: 245.5 E(32554): 2.8e-65 Smith-Waterman score: 1049; 60.9% identity (80.1% similar) in 271 aa overlap (1-269:1-258) 10 20 30 40 50 pF1KB4 MEHGSIITQARREDAL-VLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTEL :. ...::: .:.: : .: .... .:::.:.:...:::: . :.. . CCDS24 MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCV-CRDDGEALPAHSG 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 AAYK-EEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFK : :: ..: : : : ::::. .:. .::::::::::::::::: CCDS24 APLLVEENGAIPK------------QTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFK 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 PINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLD :.::::::.:.::.:..:::::::::.:::::.::::::::::::::::::::::.:::: CCDS24 PVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLD 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 RCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFD . :.:::::::::::::.: :::::::::::::..::::::::::.:::.::::: :::: CCDS24 KWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFD 170 180 190 200 210 220 240 250 260 270 pF1KB4 DMADTELLNLIPIFEELSGAEDVYTSLGQLRAP .:.:::: .:.:.::.:: ..:::. : : : CCDS24 NMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS 230 240 250 260 >>CCDS56166.1 CTDSP1 gene_id:58190|Hs108|chr2 (260 aa) initn: 1041 init1: 976 opt: 976 Z-score: 1278.8 bits: 244.3 E(32554): 6.5e-65 Smith-Waterman score: 1017; 63.2% identity (82.4% similar) in 250 aa overlap (21-269:22-257) 10 20 30 40 50 pF1KB4 MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTEL .: .... .:::.:.:...:::: . :.. . CCDS56 MVAAPWATQEQEEGRGIQPGDRGDQKSAASQKPRSRGILHSLFCCV-CRDDGEALPAHSG 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 AAYK-EEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFK : :: ..: :. .:: ::::. .:. .::::::::::::::::: CCDS56 APLLVEENGAIPKTP----VQY---------LLPEAKAQDSDKICVVIDLDETLVHSSFK 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 PINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLD :.::::::.:.::.:..:::::::::.:::::.::::::::::::::::::::::.:::: CCDS56 PVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLD 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 RCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFD . :.:::::::::::::.: :::::::::::::..::::::::::.:::.::::: :::: CCDS56 KWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFD 170 180 190 200 210 220 240 250 260 270 pF1KB4 DMADTELLNLIPIFEELSGAEDVYTSLGQLRAP .:.:::: .:.:.::.:: ..:::. : : : CCDS56 NMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS 230 240 250 260 >>CCDS10110.1 CTDSPL2 gene_id:51496|Hs108|chr15 (466 aa) initn: 497 init1: 283 opt: 509 Z-score: 664.5 bits: 131.5 E(32554): 1.1e-30 Smith-Waterman score: 509; 41.5% identity (69.1% similar) in 217 aa overlap (51-261:238-449) 30 40 50 60 70 pF1KB4 QGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCL-- : ::. .: :.:.:. ... ... . CCDS10 RPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYSSAHAE-ATYEEDWEVFDPYYFIKHVPP 210 220 230 240 250 260 80 90 100 110 120 130 pF1KB4 --QYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTH . :. . :. : . : : . .:.:::::::: :.. ...: . :. .. . . CCDS10 LTEEQLNRKPALPLKTRSTPE----FSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIY 270 280 290 300 310 320 140 150 160 170 180 190 pF1KB4 QVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLD-RCGVFRARLFRESCVFH :::: ::. :::.::....: .::::: ::: . ..:: . . : ::::: :: CCDS10 QVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCV 330 340 350 360 370 380 200 210 220 230 240 250 pF1KB4 QGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEEL :: :.:::. ::::: ::.:.:::: .. .. :..:..::: : :.:::.:::..:.: CCDS10 QGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKL 390 400 410 420 430 440 260 270 pF1KB4 SG-AEDVYTSLGQLRAP ::: CCDS10 VELNEDVRPHIRDRFRLHDLLPPD 450 460 >>CCDS11093.1 CTDNEP1 gene_id:23399|Hs108|chr17 (244 aa) initn: 402 init1: 228 opt: 415 Z-score: 546.4 bits: 108.7 E(32554): 4.1e-24 Smith-Waterman score: 454; 40.9% identity (69.9% similar) in 176 aa overlap (101-267:61-236) 80 90 100 110 120 pF1KB4 KSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHS--------SFKPINN : .:.::::::.:: . .: . CCDS11 QIRTVIQYQTVRYDILPLSPVSRNRLAQVKRKILVLDLDETLIHSHHDGVLRPTVRPGTP 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 ADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRC-G :::. . :. . .: :::.:: ::. ... .: :.::::. :.. :.: :: . CCDS11 PDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNSRS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 VFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMA ... : .:. :... : :.:::: . :: . .::::::..: ::.::.:..:::.: . CCDS11 ILKRRYYRQHCTLELGSYIKDLSVVHSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPS 160 170 180 190 200 210 250 260 270 pF1KB4 DTELLNLIPIFEELSGAEDVYTSLGQLRAP :: ::::.:... : . :: . :.. CCDS11 DTALLNLLPMLDALRFTADVRSVLSRNLHQHRLW 220 230 240 >>CCDS33023.1 TIMM50 gene_id:92609|Hs108|chr19 (456 aa) initn: 242 init1: 217 opt: 240 Z-score: 313.2 bits: 66.4 E(32554): 4e-11 Smith-Waterman score: 245; 28.7% identity (58.0% similar) in 181 aa overlap (89-265:236-401) 60 70 80 90 100 110 pF1KB4 LAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEED--QGRICVVIDLDETLVHSS ::::. .: : .:..: .:.: CCDS33 DNDPILVQQLRRTYKYFKDYRQMIIEPTSPCLLPDPLQEPYYQPPYTLVLELTGVLLHPE 210 220 230 240 250 260 120 130 140 150 160 170 pF1KB4 FKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDL .. .. : ::: .. ...... :.: :.::. . : :. : CCDS33 WSLATGWRFK---------------KRPGIETLFQQLAPLYEIVIFTSETGMTAFPLIDS 270 280 290 300 310 180 190 200 210 220 230 pF1KB4 LDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSW .: : . ::::.. . .: .:::.: :.:: .....: . .. ..: :.: .. : CCDS33 VDPHGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPW 320 330 340 350 360 370 240 250 260 270 pF1KB4 FDDMADTELLNLIPIFEE--LSGAEDVYTSLGQLRAP . : ::.: ... :.:.::: : : CCDS33 DGNSDDRVLLDLSAFLKTIALNGVEDVRTVLEHYALEDDPLAAFKQRQSRLEQEEQQRLA 380 390 400 410 420 430 CCDS33 ELSKSNKQNLFLGSLTSRLWPRSKQP 440 450 271 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:42:15 2016 done: Thu Nov 3 21:42:15 2016 Total Scan time: 2.350 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]