FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4796, 223 aa 1>>>pF1KB4796 223 - 223 aa - 223 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0348+/-0.000904; mu= 15.0618+/- 0.055 mean_var=64.2406+/-12.727, 0's: 0 Z-trim(105.4): 66 B-trim: 0 in 0/50 Lambda= 0.160018 statistics sampled from 8354 (8422) to 8354 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.259), width: 16 Scan time: 2.030 The best scores are: opt bits E(32554) CCDS9711.1 STYX gene_id:6815|Hs108|chr14 ( 223) 1485 351.4 2.6e-97 CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 ( 184) 307 79.4 1.6e-15 CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 ( 205) 307 79.5 1.8e-15 CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 ( 314) 306 79.4 2.9e-15 CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 ( 217) 297 77.2 9.2e-15 CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 ( 625) 302 78.6 9.7e-15 CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX ( 384) 298 77.6 1.2e-14 CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 ( 367) 295 76.9 1.9e-14 CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 287 74.9 4.9e-14 CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 280 73.3 1.5e-13 CCDS11253.1 SSH2 gene_id:85464|Hs108|chr17 (1423) 288 75.6 1.8e-13 CCDS74024.1 SSH2 gene_id:85464|Hs108|chr17 (1450) 288 75.6 1.8e-13 CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 ( 482) 281 73.7 2.3e-13 CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 ( 295) 276 72.4 3.4e-13 CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 271 71.3 9.3e-13 CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 266 70.0 1.2e-12 CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 271 71.5 1.5e-12 CCDS55882.1 SSH1 gene_id:54434|Hs108|chr12 ( 692) 270 71.3 1.8e-12 CCDS53825.1 SSH1 gene_id:54434|Hs108|chr12 ( 703) 270 71.3 1.8e-12 CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 265 69.9 2e-12 CCDS33766.2 DUSP7 gene_id:1849|Hs108|chr3 ( 419) 266 70.2 2.2e-12 CCDS9121.1 SSH1 gene_id:54434|Hs108|chr12 (1049) 270 71.4 2.5e-12 CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 ( 394) 265 70.0 2.5e-12 CCDS9033.1 DUSP6 gene_id:1848|Hs108|chr12 ( 381) 262 69.3 3.9e-12 CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 ( 659) 259 68.7 9.8e-12 CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 241 64.2 6.4e-11 CCDS11469.1 DUSP3 gene_id:1845|Hs108|chr17 ( 185) 240 64.0 7.4e-11 >>CCDS9711.1 STYX gene_id:6815|Hs108|chr14 (223 aa) initn: 1485 init1: 1485 opt: 1485 Z-score: 1860.6 bits: 351.4 E(32554): 2.6e-97 Smith-Waterman score: 1485; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223) 10 20 30 40 50 60 pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 130 140 150 160 170 180 190 200 210 220 pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG ::::::::::::::::::::::::::::::::::::::::::: CCDS97 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 190 200 210 220 >>CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 (184 aa) initn: 279 init1: 239 opt: 307 Z-score: 392.0 bits: 79.4 E(32554): 1.6e-15 Smith-Waterman score: 307; 37.8% identity (67.1% similar) in 143 aa overlap (29-171:5-139) 10 20 30 40 50 60 pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI :..:::::..: ...: .. :.:. .::: CCDS44 MGNGMNKILPGLYIGNFKDARDAEQ--LSKNKVTHI 10 20 30 70 80 90 100 110 120 pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG . .... .: .. . .:: . ::.: .:. : : . .:: : . ::: CCDS44 LSVHDSA-----RPMLEGV-KYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHC 40 50 60 70 80 130 140 150 160 170 180 pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI ::.:::...:::::: . . ..::. :. : : :::.:: .::::.: CCDS44 LAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQ 90 100 110 120 130 140 190 200 210 220 pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG CCDS44 WLKEEYGESPLQDAEEAKNILAAPGILKFWAFLRRL 150 160 170 180 >>CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 (205 aa) initn: 279 init1: 239 opt: 307 Z-score: 391.3 bits: 79.5 E(32554): 1.8e-15 Smith-Waterman score: 307; 37.8% identity (67.1% similar) in 143 aa overlap (29-171:5-139) 10 20 30 40 50 60 pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI :..:::::..: ...: .. :.:. .::: CCDS69 MGNGMNKILPGLYIGNFKDARDAEQ--LSKNKVTHI 10 20 30 70 80 90 100 110 120 pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG . .... .: .. . .:: . ::.: .:. : : . .:: : . ::: CCDS69 LSVHDSA-----RPMLEGV-KYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHC 40 50 60 70 80 130 140 150 160 170 180 pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI ::.:::...:::::: . . ..::. :. : : :::.:: .::::.: CCDS69 LAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQ 90 100 110 120 130 140 190 200 210 220 pF1KB4 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG CCDS69 WLKEEYGESPLQDAEEAKNILGKYKEQGRTEPQPGARRWSSFPALAPLTYDNYTTET 150 160 170 180 190 200 >>CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 (314 aa) initn: 292 init1: 238 opt: 306 Z-score: 387.4 bits: 79.4 E(32554): 2.9e-15 Smith-Waterman score: 306; 41.8% identity (65.1% similar) in 146 aa overlap (31-175:175-312) 10 20 30 40 50 60 pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI :::: :::: : . .: : :: ::: . CCDS20 EAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLG--SCSHSSDLQGLQACGITAV 150 160 170 180 190 200 70 80 90 100 110 pF1KB4 ICIRQNIEANFIKPN-FQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVH . :. :. :: :. :::: . . :: . .: .: . ::: . ::.:::: CCDS20 L----NVSASC--PNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVH 210 220 230 240 250 120 130 140 150 160 170 pF1KB4 GNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLT .:::::::.. .::.:.. .. .:: .:..:: :.:: .:. :: ..:. : CCDS20 CQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH 260 270 280 290 300 310 180 190 200 210 220 pF1KB4 IQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG >>CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 (217 aa) initn: 243 init1: 218 opt: 297 Z-score: 378.5 bits: 77.2 E(32554): 9.2e-15 Smith-Waterman score: 297; 37.9% identity (65.7% similar) in 140 aa overlap (32-171:69-201) 10 20 30 40 50 60 pF1KB4 EDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHII : : :.:: ..: : .:.:. .:::. CCDS22 RIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHD--LDTLKKNKVTHIL 40 50 60 70 80 90 70 80 90 100 110 120 pF1KB4 CIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGN . ..: :.. : : ..: : : ::. .:: :::. . . : :::: : CCDS22 NVAYGVENAFLSD-----FTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCN 100 110 120 130 140 150 130 140 150 160 170 180 pF1KB4 AGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQ ::.::.::.::...:.. .. .::. :.. : : ::.::..::. :. CCDS22 AGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDR 160 170 180 190 200 210 190 200 210 220 pF1KB4 MMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG CCDS22 IQENSS >>CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 (625 aa) initn: 290 init1: 259 opt: 302 Z-score: 378.1 bits: 78.6 E(32554): 9.7e-15 Smith-Waterman score: 302; 37.8% identity (68.5% similar) in 143 aa overlap (29-171:161-297) 10 20 30 40 50 pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGIT . .::: :.:: ...... : . ..::. CCDS77 SCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDL--MTQNGIS 140 150 160 170 180 60 70 80 90 100 110 pF1KB4 HIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLV ... : . ::.: :.. . : :: :... .. . :::: . . .:.: CCDS77 YVL----NASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIV 190 200 210 220 230 240 120 130 140 150 160 170 pF1KB4 HGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKL : :::::::...:::::.:.::. ::. .:..:: :.:: .:. :: ::: CCDS77 HCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLA 250 260 270 280 290 300 180 190 200 210 220 pF1KB4 TIQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG CCDS77 ALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPAPPTP 310 320 330 340 350 360 >>CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX (384 aa) initn: 253 init1: 202 opt: 298 Z-score: 376.2 bits: 77.6 E(32554): 1.2e-14 Smith-Waterman score: 298; 36.4% identity (66.0% similar) in 162 aa overlap (14-171:185-341) 10 20 30 pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYP---MRREMQ-EILPGLFLG : :.: : : .: . .:::.:.:: CCDS14 GPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLG 160 170 180 190 200 210 40 50 60 70 80 90 pF1KB4 PYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFF :. ...: : : :: .:. . :. ::.. : . :.: . :.:. .:. ::: CCDS14 --SARDSANLESLAKLGIRYILNVTPNLP-NFFEKNGD--FHYKQIPISDHWSQNLSRFF 220 230 240 250 260 100 110 120 130 140 150 pF1KB4 PMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINP : . :::: .:... :::: ::.:::.. ..::.:. . .. ::. :.... :.: CCDS14 PEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISP 270 280 290 300 310 320 160 170 180 190 200 210 pF1KB4 NAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVAT : .:. :: ..: CCDS14 NFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT 330 340 350 360 370 380 >>CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 (367 aa) initn: 260 init1: 228 opt: 295 Z-score: 372.7 bits: 76.9 E(32554): 1.9e-14 Smith-Waterman score: 295; 40.1% identity (65.3% similar) in 147 aa overlap (31-176:176-314) 10 20 30 40 50 60 pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI :::: :.:: :. :. .:. ::: . CCDS43 SLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLG--SAYHASRKDMLDALGITAL 150 160 170 180 190 200 70 80 90 100 110 pF1KB4 ICIRQNIEANFIKPN-FQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVH : :. :: :: :. ..: . . :: .: .: . .:::. . ::.:.:: CCDS43 I----NVSANC--PNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVH 210 220 230 240 250 120 130 140 150 160 170 pF1KB4 GNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLT .:::::::.. .::.:.: .: .:: .:..:: :.:: .:. :: ..:. :: CCDS43 CQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHC 260 270 280 290 300 310 180 190 200 210 220 pF1KB4 IQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG CCDS43 SAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC 320 330 340 350 360 >>CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 (235 aa) initn: 271 init1: 213 opt: 287 Z-score: 365.5 bits: 74.9 E(32554): 4.9e-14 Smith-Waterman score: 287; 36.1% identity (59.2% similar) in 169 aa overlap (29-192:5-165) 10 20 30 40 50 60 pF1KB4 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI : ..::::.:: . .: . : : .. :::: CCDS13 MGNGMTKVLPGLYLGNFIDA--KDLDQLGRNKITHI 10 20 30 70 80 90 100 110 120 pF1KB4 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG : :... . : .:.. :: . .::.: : . : .:: ::. ::: CCDS13 ISIHESPQ-----PLLQDI-TYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHC 40 50 60 70 80 130 140 150 160 170 180 pF1KB4 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI ::::::...: ::.: . :. .::.. .. : ::: :: .::.:. :: CCDS13 FAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKLRR 90 100 110 120 130 140 190 200 210 220 pF1KB4 QMM-----SPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG :. ::.. :. : CCDS13 QLEERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAASEGTVQRLVPRTPREA 150 160 170 180 190 200 >>CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 (232 aa) initn: 271 init1: 213 opt: 280 Z-score: 356.9 bits: 73.3 E(32554): 1.5e-13 Smith-Waterman score: 280; 36.1% identity (59.0% similar) in 166 aa overlap (32-192:5-162) 10 20 30 40 50 60 pF1KB4 EDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHII .::::.:: . .: . : : .. ::::: CCDS82 MTEGVLPGLYLGNFIDA--KDLDQLGRNKITHII 10 20 30 70 80 90 100 110 120 pF1KB4 CIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGN :... .: .:.. :: . .::.: : . : .:: ::. ::: CCDS82 SIHES-----PQPLLQDI-TYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCF 40 50 60 70 80 130 140 150 160 170 180 pF1KB4 AGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQ ::::::...: ::.: . :. .::.. .. : ::: :: .::.:. :: : CCDS82 AGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKLRRQ 90 100 110 120 130 140 190 200 210 220 pF1KB4 MM-----SPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG . ::.. :. : CCDS82 LEERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAASEGTVQRLVPRTPREAH 150 160 170 180 190 200 223 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:43:42 2016 done: Thu Nov 3 21:43:43 2016 Total Scan time: 2.030 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]