Result of FASTA (omim) for
pF1KB4806
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4806, 1137 aa
1>>>pF1KB4806 1137 - 1137 aa - 1137 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.3065+/-0.000435; mu= -14.6392+/- 0.027
mean_var=449.1345+/-93.810, 0's: 0 Z-trim(123.0): 94 B-trim: 808 in 1/55
Lambda= 0.060518
statistics sampled from 42026 (42174) to 42026 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.494), width: 16
Scan time: 18.120
The best scores are: opt bits E(85289)
NP_005409 (OMIM: 140750) suppression of tumorigeni (1137) 7608 679.5 3.1e-194
XP_011518620 (OMIM: 140750) PREDICTED: suppression (1137) 7608 679.5 3.1e-194
NP_998783 (OMIM: 140750) suppression of tumorigeni (1137) 7608 679.5 3.1e-194
XP_005253134 (OMIM: 140750) PREDICTED: suppression (1167) 7608 679.5 3.2e-194
XP_016873675 (OMIM: 140750) PREDICTED: suppression ( 957) 6372 571.5 8.3e-162
XP_011518624 (OMIM: 140750) PREDICTED: suppression ( 947) 5780 519.9 3e-146
XP_011518623 (OMIM: 140750) PREDICTED: suppression ( 967) 5283 476.5 3.5e-133
XP_011518622 (OMIM: 140750) PREDICTED: suppression ( 977) 5283 476.5 3.5e-133
XP_016873671 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_011518617 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_011518618 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_011518614 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_011518615 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_011518619 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_011518616 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_016873672 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_011518613 (OMIM: 140750) PREDICTED: suppression (1157) 5283 476.5 4e-133
XP_011518612 (OMIM: 140750) PREDICTED: suppression (1177) 5283 476.5 4.1e-133
XP_011518611 (OMIM: 140750) PREDICTED: suppression (1187) 5283 476.5 4.1e-133
XP_005253140 (OMIM: 140750) PREDICTED: suppression ( 717) 4559 413.2 2.9e-114
NP_631896 (OMIM: 140750) suppression of tumorigeni ( 717) 4559 413.2 2.9e-114
XP_011518631 (OMIM: 140750) PREDICTED: suppression ( 717) 4559 413.2 2.9e-114
XP_011518626 (OMIM: 140750) PREDICTED: suppression ( 747) 4559 413.2 3e-114
XP_016873674 (OMIM: 140750) PREDICTED: suppression ( 977) 4047 368.6 1.1e-100
XP_011518621 (OMIM: 140750) PREDICTED: suppression ( 977) 4047 368.6 1.1e-100
XP_016873673 (OMIM: 140750) PREDICTED: suppression ( 977) 4047 368.6 1.1e-100
XP_011518630 (OMIM: 140750) PREDICTED: suppression ( 737) 2330 218.6 1.1e-55
XP_011518629 (OMIM: 140750) PREDICTED: suppression ( 737) 2330 218.6 1.1e-55
XP_016873676 (OMIM: 140750) PREDICTED: suppression ( 737) 2330 218.6 1.1e-55
XP_011518627 (OMIM: 140750) PREDICTED: suppression ( 737) 2330 218.6 1.1e-55
XP_011518628 (OMIM: 140750) PREDICTED: suppression ( 737) 2330 218.6 1.1e-55
XP_011518625 (OMIM: 140750) PREDICTED: suppression ( 767) 2330 218.6 1.2e-55
XP_011540489 (OMIM: 615111) PREDICTED: DENN domain ( 459) 1237 123.0 4.2e-27
XP_011540492 (OMIM: 615111) PREDICTED: DENN domain ( 459) 1237 123.0 4.2e-27
NP_001258762 (OMIM: 615111) DENN domain-containing ( 468) 1237 123.0 4.2e-27
NP_079177 (OMIM: 615111) DENN domain-containing pr ( 471) 1237 123.0 4.3e-27
XP_006710984 (OMIM: 615111) PREDICTED: DENN domain ( 485) 1237 123.0 4.4e-27
XP_011540491 (OMIM: 615111) PREDICTED: DENN domain ( 415) 883 92.1 7.8e-18
XP_006710986 (OMIM: 615111) PREDICTED: DENN domain ( 415) 883 92.1 7.8e-18
XP_006710985 (OMIM: 615111) PREDICTED: DENN domain ( 415) 883 92.1 7.8e-18
XP_006710987 (OMIM: 615111) PREDICTED: DENN domain ( 415) 883 92.1 7.8e-18
XP_016857878 (OMIM: 615111) PREDICTED: DENN domain ( 235) 724 78.0 7.4e-14
XP_016857876 (OMIM: 615111) PREDICTED: DENN domain ( 291) 669 73.3 2.5e-12
XP_016857877 (OMIM: 615111) PREDICTED: DENN domain ( 291) 669 73.3 2.5e-12
XP_016857875 (OMIM: 615111) PREDICTED: DENN domain ( 291) 669 73.3 2.5e-12
NP_079096 (OMIM: 613633) DENN domain-containing pr ( 559) 379 48.1 0.00017
XP_005252170 (OMIM: 613633) PREDICTED: DENN domain ( 574) 379 48.2 0.00018
NP_001287787 (OMIM: 613292) DENN domain-containing ( 396) 374 47.6 0.00018
XP_011517189 (OMIM: 613633) PREDICTED: DENN domain ( 592) 379 48.2 0.00018
NP_065997 (OMIM: 613633) DENN domain-containing pr (1009) 379 48.3 0.00028
>>NP_005409 (OMIM: 140750) suppression of tumorigenicity (1137 aa)
initn: 7608 init1: 7608 opt: 7608 Z-score: 3608.1 bits: 679.5 E(85289): 3.1e-194
Smith-Waterman score: 7608; 100.0% identity (100.0% similar) in 1137 aa overlap (1-1137:1-1137)
10 20 30 40 50 60
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 RRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 PGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 FVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 ELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 TLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KB4 MFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN
1090 1100 1110 1120 1130
>>XP_011518620 (OMIM: 140750) PREDICTED: suppression of (1137 aa)
initn: 7608 init1: 7608 opt: 7608 Z-score: 3608.1 bits: 679.5 E(85289): 3.1e-194
Smith-Waterman score: 7608; 100.0% identity (100.0% similar) in 1137 aa overlap (1-1137:1-1137)
10 20 30 40 50 60
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 RRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 PGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 FVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 ELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 TLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KB4 MFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN
1090 1100 1110 1120 1130
>>NP_998783 (OMIM: 140750) suppression of tumorigenicity (1137 aa)
initn: 7608 init1: 7608 opt: 7608 Z-score: 3608.1 bits: 679.5 E(85289): 3.1e-194
Smith-Waterman score: 7608; 100.0% identity (100.0% similar) in 1137 aa overlap (1-1137:1-1137)
10 20 30 40 50 60
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 RRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 RRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 PGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 PGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 FVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 FVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 ELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 ELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 TLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KB4 MFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN
1090 1100 1110 1120 1130
>>XP_005253134 (OMIM: 140750) PREDICTED: suppression of (1167 aa)
initn: 7608 init1: 7608 opt: 7608 Z-score: 3608.0 bits: 679.5 E(85289): 3.2e-194
Smith-Waterman score: 7608; 100.0% identity (100.0% similar) in 1137 aa overlap (1-1137:31-1167)
10 20 30
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQS
::::::::::::::::::::::::::::::
XP_005 MTSRKNGGGAHSWQETPWEQRRALGLQRAEMTMTANKNSSITHGAGGTKAPRGTLSRSQS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 VSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 TCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB4 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB4 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB4 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB4 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB4 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB4 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
730 740 750 760 770 780
760 770 780 790 800 810
pF1KB4 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSK
790 800 810 820 830 840
820 830 840 850 860 870
pF1KB4 VLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLE
850 860 870 880 890 900
880 890 900 910 920 930
pF1KB4 HVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFI
910 920 930 940 950 960
940 950 960 970 980 990
pF1KB4 PVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPR
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KB4 KLQAALEQALERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLQAALEQALERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEK
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KB4 GERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEE
1090 1100 1110 1120 1130 1140
1120 1130
pF1KB4 LPDTEQSGMNKFLRGLGNKMKFLHKKN
:::::::::::::::::::::::::::
XP_005 LPDTEQSGMNKFLRGLGNKMKFLHKKN
1150 1160
>>XP_016873675 (OMIM: 140750) PREDICTED: suppression of (957 aa)
initn: 6372 init1: 6372 opt: 6372 Z-score: 3026.0 bits: 571.5 E(85289): 8.3e-162
Smith-Waterman score: 6372; 100.0% identity (100.0% similar) in 957 aa overlap (181-1137:1-957)
160 170 180 190 200 210
pF1KB4 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
::::::::::::::::::::::::::::::
XP_016 MSMCGEKREGSGSEWAASEGCPSLGCPSVV
10 20 30
220 230 240 250 260 270
pF1KB4 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB4 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB4 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB4 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB4 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB4 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB4 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB4 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
460 470 480 490 500 510
700 710 720 730 740 750
pF1KB4 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
520 530 540 550 560 570
760 770 780 790 800 810
pF1KB4 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSK
580 590 600 610 620 630
820 830 840 850 860 870
pF1KB4 VLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLE
640 650 660 670 680 690
880 890 900 910 920 930
pF1KB4 HVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFI
700 710 720 730 740 750
940 950 960 970 980 990
pF1KB4 PVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPR
760 770 780 790 800 810
1000 1010 1020 1030 1040 1050
pF1KB4 KLQAALEQALERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLQAALEQALERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEK
820 830 840 850 860 870
1060 1070 1080 1090 1100 1110
pF1KB4 GERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEE
880 890 900 910 920 930
1120 1130
pF1KB4 LPDTEQSGMNKFLRGLGNKMKFLHKKN
:::::::::::::::::::::::::::
XP_016 LPDTEQSGMNKFLRGLGNKMKFLHKKN
940 950
>>XP_011518624 (OMIM: 140750) PREDICTED: suppression of (947 aa)
initn: 5780 init1: 5780 opt: 5780 Z-score: 2746.7 bits: 519.9 E(85289): 3e-146
Smith-Waterman score: 5780; 100.0% identity (100.0% similar) in 857 aa overlap (1-857:31-887)
10 20 30
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQS
::::::::::::::::::::::::::::::
XP_011 MTSRKNGGGAHSWQETPWEQRRALGLQRAEMTMTANKNSSITHGAGGTKAPRGTLSRSQS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 VSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 TCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB4 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB4 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB4 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB4 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB4 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB4 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
730 740 750 760 770 780
760 770 780 790 800 810
pF1KB4 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSK
790 800 810 820 830 840
820 830 840 850 860 870
pF1KB4 VLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLE
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEFSGGLHIYAAHTC
850 860 870 880 890 900
880 890 900 910 920 930
pF1KB4 HVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFI
XP_011 CGTKEEARQTPGTAALARPERQQFLLPSPLESLTTFHPCDSPREVAL
910 920 930 940
>>XP_011518623 (OMIM: 140750) PREDICTED: suppression of (967 aa)
initn: 5283 init1: 5283 opt: 5283 Z-score: 2512.1 bits: 476.5 E(85289): 3.5e-133
Smith-Waterman score: 5730; 97.7% identity (97.7% similar) in 877 aa overlap (1-857:31-907)
10 20 30
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQS
::::::::::::::::::::::::::::::
XP_011 MTSRKNGGGAHSWQETPWEQRRALGLQRAEMTMTANKNSSITHGAGGTKAPRGTLSRSQS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 VSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 TCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB4 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB4 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB4 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB4 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB4 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB4 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
730 740 750 760 770 780
760 770 780 790
pF1KB4 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLL--------------------PSGKGP
:::::::::::::::::::::::::::::::::: ::::::
XP_011 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLFALLEWRWIKKGRKEAKKGMPSGKGP
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB4 RLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTF
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB4 LPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLS
:::::::
XP_011 LPGAGNEFSGGLHIYAAHTCCGTKEEARQTPGTAALARPERQQFLLPSPLESLTTFHPCD
910 920 930 940 950 960
>>XP_011518622 (OMIM: 140750) PREDICTED: suppression of (977 aa)
initn: 5283 init1: 5283 opt: 5283 Z-score: 2512.0 bits: 476.5 E(85289): 3.5e-133
Smith-Waterman score: 6050; 97.8% identity (97.8% similar) in 927 aa overlap (1-907:31-957)
10 20 30
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQS
::::::::::::::::::::::::::::::
XP_011 MTSRKNGGGAHSWQETPWEQRRALGLQRAEMTMTANKNSSITHGAGGTKAPRGTLSRSQS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 VSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 TCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLR
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB4 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSF
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB4 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRR
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB4 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB4 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB4 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLE
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB4 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDA
730 740 750 760 770 780
760 770 780 790
pF1KB4 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLL--------------------PSGKGP
:::::::::::::::::::::::::::::::::: ::::::
XP_011 KDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLFALLEWRWIKKGRKEAKKGMPSGKGP
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB4 RLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTF
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB4 LPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSHGP
910 920 930 940 950 960
920 930 940 950 960 970
pF1KB4 SCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMV
XP_011 TDVPPKPETALFQIFVR
970
>>XP_016873671 (OMIM: 140750) PREDICTED: suppression of (1157 aa)
initn: 5283 init1: 5283 opt: 5283 Z-score: 2510.9 bits: 476.5 E(85289): 4e-133
Smith-Waterman score: 7558; 98.3% identity (98.3% similar) in 1157 aa overlap (1-1137:1-1157)
10 20 30 40 50 60
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
730 740 750 760 770 780
790 800 810 820
pF1KB4 RRLL--------------------PSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRG
:::: ::::::::::::::::::::::::::::::::::::
XP_016 RRLLFALLEWRWIKKGRKEAKKGMPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRG
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB4 ISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTC
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB4 LSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDI
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB4 VCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQAL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB4 ERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAF
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KB4 RKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMN
1090 1100 1110 1120 1130 1140
1130
pF1KB4 KFLRGLGNKMKFLHKKN
:::::::::::::::::
XP_016 KFLRGLGNKMKFLHKKN
1150
>>XP_011518617 (OMIM: 140750) PREDICTED: suppression of (1157 aa)
initn: 5283 init1: 5283 opt: 5283 Z-score: 2510.9 bits: 476.5 E(85289): 4e-133
Smith-Waterman score: 7558; 98.3% identity (98.3% similar) in 1157 aa overlap (1-1137:1-1157)
10 20 30 40 50 60
pF1KB4 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGST
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYC
730 740 750 760 770 780
790 800 810 820
pF1KB4 RRLL--------------------PSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRG
:::: ::::::::::::::::::::::::::::::::::::
XP_011 RRLLFALLEWRWIKKGRKEAKKGMPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRG
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB4 ISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTC
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB4 LSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDI
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB4 VCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQAL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB4 ERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAF
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KB4 RKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMN
1090 1100 1110 1120 1130 1140
1130
pF1KB4 KFLRGLGNKMKFLHKKN
:::::::::::::::::
XP_011 KFLRGLGNKMKFLHKKN
1150
1137 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:31:18 2016 done: Thu Nov 3 15:31:20 2016
Total Scan time: 18.120 Total Display time: 0.400
Function used was FASTA [36.3.4 Apr, 2011]