FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4823, 741 aa 1>>>pF1KB4823 741 - 741 aa - 741 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4538+/-0.000341; mu= 13.2357+/- 0.022 mean_var=181.5775+/-36.546, 0's: 0 Z-trim(120.2): 90 B-trim: 43 in 1/59 Lambda= 0.095179 statistics sampled from 35054 (35145) to 35054 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.412), width: 16 Scan time: 12.540 The best scores are: opt bits E(85289) NP_056648 (OMIM: 601218) double-stranded RNA-speci ( 741) 4938 690.7 5.8e-198 XP_016883737 (OMIM: 601218) PREDICTED: double-stra ( 741) 4938 690.7 5.8e-198 XP_016883736 (OMIM: 601218) PREDICTED: double-stra ( 741) 4938 690.7 5.8e-198 XP_016883739 (OMIM: 601218) PREDICTED: double-stra ( 741) 4938 690.7 5.8e-198 XP_016883740 (OMIM: 601218) PREDICTED: double-stra ( 741) 4938 690.7 5.8e-198 XP_016883738 (OMIM: 601218) PREDICTED: double-stra ( 741) 4938 690.7 5.8e-198 XP_006724017 (OMIM: 601218) PREDICTED: double-stra ( 769) 4938 690.7 5.9e-198 XP_016883732 (OMIM: 601218) PREDICTED: double-stra ( 769) 4938 690.7 5.9e-198 XP_011527727 (OMIM: 601218) PREDICTED: double-stra ( 772) 4938 690.7 5.9e-198 XP_016883731 (OMIM: 601218) PREDICTED: double-stra ( 790) 4938 690.7 6e-198 NP_056649 (OMIM: 601218) double-stranded RNA-speci ( 714) 4745 664.1 5.3e-190 XP_016883743 (OMIM: 601218) PREDICTED: double-stra ( 714) 4745 664.1 5.3e-190 XP_016883735 (OMIM: 601218) PREDICTED: double-stra ( 742) 4745 664.2 5.5e-190 XP_016883733 (OMIM: 601218) PREDICTED: double-stra ( 763) 4745 664.2 5.6e-190 XP_016883741 (OMIM: 601218) PREDICTED: double-stra ( 733) 4445 623.0 1.4e-177 NP_001153702 (OMIM: 601218) double-stranded RNA-sp ( 674) 3082 435.8 2.8e-121 XP_016883745 (OMIM: 601218) PREDICTED: double-stra ( 674) 3082 435.8 2.8e-121 NP_001103 (OMIM: 601218) double-stranded RNA-speci ( 701) 3082 435.8 2.9e-121 XP_016883744 (OMIM: 601218) PREDICTED: double-stra ( 701) 3082 435.8 2.9e-121 XP_016883742 (OMIM: 601218) PREDICTED: double-stra ( 723) 3082 435.8 3e-121 XP_016883734 (OMIM: 601218) PREDICTED: double-stra ( 750) 3082 435.8 3.1e-121 XP_011527734 (OMIM: 601218) PREDICTED: double-stra ( 385) 2576 366.0 1.6e-100 NP_061172 (OMIM: 602065) double-stranded RNA-speci ( 739) 940 141.7 1.1e-32 XP_011507363 (OMIM: 127400,146920,615010) PREDICTE ( 905) 550 88.2 1.6e-16 XP_016855526 (OMIM: 127400,146920,615010) PREDICTE ( 905) 550 88.2 1.6e-16 XP_006711175 (OMIM: 127400,146920,615010) PREDICTE ( 931) 550 88.2 1.6e-16 NP_001020278 (OMIM: 127400,146920,615010) double-s ( 931) 550 88.2 1.6e-16 NP_001180424 (OMIM: 127400,146920,615010) double-s ( 931) 550 88.2 1.6e-16 XP_006711174 (OMIM: 127400,146920,615010) PREDICTE ( 931) 550 88.2 1.6e-16 XP_006711176 (OMIM: 127400,146920,615010) PREDICTE ( 931) 550 88.2 1.6e-16 NP_056656 (OMIM: 127400,146920,615010) double-stra (1181) 550 88.3 1.9e-16 NP_056655 (OMIM: 127400,146920,615010) double-stra (1200) 550 88.3 2e-16 NP_001102 (OMIM: 127400,146920,615010) double-stra (1226) 550 88.3 2e-16 XP_011507364 (OMIM: 127400,146920,615010) PREDICTE (1232) 550 88.3 2e-16 XP_006711172 (OMIM: 127400,146920,615010) PREDICTE (1236) 550 88.3 2e-16 XP_011507362 (OMIM: 127400,146920,615010) PREDICTE (1269) 550 88.3 2e-16 XP_005262802 (OMIM: 614130) PREDICTED: adenosine d ( 553) 345 59.8 3.4e-08 NP_001152767 (OMIM: 614130) adenosine deaminase do ( 558) 345 59.9 3.4e-08 XP_005262801 (OMIM: 614130) PREDICTED: adenosine d ( 565) 345 59.9 3.4e-08 NP_001152757 (OMIM: 614130) adenosine deaminase do ( 565) 345 59.9 3.4e-08 NP_640336 (OMIM: 614130) adenosine deaminase domai ( 576) 345 59.9 3.5e-08 XP_005262798 (OMIM: 614130) PREDICTED: adenosine d ( 576) 345 59.9 3.5e-08 XP_011529905 (OMIM: 614130) PREDICTED: adenosine d ( 576) 345 59.9 3.5e-08 XP_005262800 (OMIM: 614130) PREDICTED: adenosine d ( 576) 345 59.9 3.5e-08 XP_011526289 (OMIM: 603182) PREDICTED: interleukin ( 563) 343 59.6 4.1e-08 XP_016882254 (OMIM: 603182) PREDICTED: interleukin ( 563) 343 59.6 4.1e-08 XP_016882253 (OMIM: 603182) PREDICTED: interleukin ( 633) 343 59.6 4.5e-08 NP_703194 (OMIM: 603182) interleukin enhancer-bind ( 690) 343 59.7 4.8e-08 NP_004507 (OMIM: 603182) interleukin enhancer-bind ( 702) 343 59.7 4.8e-08 NP_001131145 (OMIM: 603182) interleukin enhancer-b ( 706) 343 59.7 4.8e-08 >>NP_056648 (OMIM: 601218) double-stranded RNA-specific (741 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3675.1 bits: 690.7 E(85289): 5.8e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:1-741) 10 20 30 40 50 60 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 670 680 690 700 710 720 730 740 pF1KB4 KAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::: NP_056 KAGLGAWVEKPTEQDQFSLTP 730 740 >>XP_016883737 (OMIM: 601218) PREDICTED: double-stranded (741 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3675.1 bits: 690.7 E(85289): 5.8e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:1-741) 10 20 30 40 50 60 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 670 680 690 700 710 720 730 740 pF1KB4 KAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::: XP_016 KAGLGAWVEKPTEQDQFSLTP 730 740 >>XP_016883736 (OMIM: 601218) PREDICTED: double-stranded (741 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3675.1 bits: 690.7 E(85289): 5.8e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:1-741) 10 20 30 40 50 60 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 670 680 690 700 710 720 730 740 pF1KB4 KAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::: XP_016 KAGLGAWVEKPTEQDQFSLTP 730 740 >>XP_016883739 (OMIM: 601218) PREDICTED: double-stranded (741 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3675.1 bits: 690.7 E(85289): 5.8e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:1-741) 10 20 30 40 50 60 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 670 680 690 700 710 720 730 740 pF1KB4 KAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::: XP_016 KAGLGAWVEKPTEQDQFSLTP 730 740 >>XP_016883740 (OMIM: 601218) PREDICTED: double-stranded (741 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3675.1 bits: 690.7 E(85289): 5.8e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:1-741) 10 20 30 40 50 60 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 670 680 690 700 710 720 730 740 pF1KB4 KAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::: XP_016 KAGLGAWVEKPTEQDQFSLTP 730 740 >>XP_016883738 (OMIM: 601218) PREDICTED: double-stranded (741 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3675.1 bits: 690.7 E(85289): 5.8e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:1-741) 10 20 30 40 50 60 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 670 680 690 700 710 720 730 740 pF1KB4 KAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::: XP_016 KAGLGAWVEKPTEQDQFSLTP 730 740 >>XP_006724017 (OMIM: 601218) PREDICTED: double-stranded (769 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3674.9 bits: 690.7 E(85289): 5.9e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:29-769) 10 20 30 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDGST :::::::::::::::::::::::::::::::: XP_006 MKIPRMKTPCQPDRNSLRQSRNPQKYFAMDIEDEENMSSSSTDVKENRNLDNVSPKDGST 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 PGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 VPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 FFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 GKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALND 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 CHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCG 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB4 DARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHP 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB4 NRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSL 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB4 LSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQP 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB4 GKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKI 670 680 690 700 710 720 700 710 720 730 740 pF1KB4 TKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP 730 740 750 760 >>XP_016883732 (OMIM: 601218) PREDICTED: double-stranded (769 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3674.9 bits: 690.7 E(85289): 5.9e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:29-769) 10 20 30 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDGST :::::::::::::::::::::::::::::::: XP_016 MKIPRMKTPCQPDRNSLRQSRNPQKYFAMDIEDEENMSSSSTDVKENRNLDNVSPKDGST 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 PGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 VPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 FFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 GKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALND 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 CHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSPCG 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB4 DARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHP 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB4 NRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSL 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB4 LSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQP 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB4 GKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKI 670 680 690 700 710 720 700 710 720 730 740 pF1KB4 TKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP 730 740 750 760 >>XP_011527727 (OMIM: 601218) PREDICTED: double-stranded (772 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3674.9 bits: 690.7 E(85289): 5.9e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:32-772) 10 20 30 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDG :::::::::::::::::::::::::::::: XP_011 EGKHMVFIQWTQGADRNSLRQSRNPQKYFAMDIEDEENMSSSSTDVKENRNLDNVSPKDG 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 STPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIK 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 PGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASE 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 AHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 SPVPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVD 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 GQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 VLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLAL 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 NDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSP 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB4 CGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADR 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB4 HPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQG 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB4 SLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEAR 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB4 QPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRS 670 680 690 700 710 720 700 710 720 730 740 pF1KB4 KITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP 730 740 750 760 770 >>XP_016883731 (OMIM: 601218) PREDICTED: double-stranded (790 aa) initn: 4938 init1: 4938 opt: 4938 Z-score: 3674.7 bits: 690.7 E(85289): 6e-198 Smith-Waterman score: 4938; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:50-790) 10 20 30 pF1KB4 MDIEDEENMSSSSTDVKENRNLDNVSPKDG :::::::::::::::::::::::::::::: XP_016 RRYKRRRKKRSERKDRNSLRQSRNPQKYFAMDIEDEENMSSSSTDVKENRNLDNVSPKDG 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB4 STPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIK 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB4 PGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASE 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB4 AHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSA 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB4 SPVPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPVPASLAQPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVD 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB4 GQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRL 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB4 VLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLAL 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB4 NDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSP 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB4 CGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADR 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB4 HPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQG 560 570 580 590 600 610 580 590 600 610 620 630 pF1KB4 SLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEAR 620 630 640 650 660 670 640 650 660 670 680 690 pF1KB4 QPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPGKAPNFSVNWTVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRS 680 690 700 710 720 730 700 710 720 730 740 pF1KB4 KITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP 740 750 760 770 780 790 741 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 21:03:52 2016 done: Mon Nov 7 21:03:53 2016 Total Scan time: 12.540 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]