FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4828, 291 aa 1>>>pF1KB4828 291 - 291 aa - 291 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8568+/-0.000699; mu= 14.1590+/- 0.043 mean_var=90.6230+/-17.742, 0's: 0 Z-trim(111.9): 37 B-trim: 0 in 0/52 Lambda= 0.134727 statistics sampled from 12746 (12782) to 12746 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.393), width: 16 Scan time: 1.550 The best scores are: opt bits E(32554) CCDS7213.1 MARCH8 gene_id:220972|Hs108|chr10 ( 291) 2010 400.0 1e-111 CCDS60519.1 MARCH8 gene_id:220972|Hs108|chr10 ( 573) 1536 308.1 9.7e-84 CCDS54814.1 MARCH1 gene_id:55016|Hs108|chr4 ( 289) 1246 251.5 5.3e-67 CCDS3806.1 MARCH1 gene_id:55016|Hs108|chr4 ( 272) 1190 240.6 9.5e-64 CCDS12202.1 MARCH2 gene_id:51257|Hs108|chr19 ( 246) 322 71.9 5.4e-13 CCDS4141.1 MARCH3 gene_id:115123|Hs108|chr5 ( 253) 293 66.2 2.7e-11 >>CCDS7213.1 MARCH8 gene_id:220972|Hs108|chr10 (291 aa) initn: 2010 init1: 2010 opt: 2010 Z-score: 2118.9 bits: 400.0 E(32554): 1e-111 Smith-Waterman score: 2010; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291) 10 20 30 40 50 60 pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV 250 260 270 280 290 >>CCDS60519.1 MARCH8 gene_id:220972|Hs108|chr10 (573 aa) initn: 1526 init1: 1526 opt: 1536 Z-score: 1616.9 bits: 308.1 E(32554): 9.7e-84 Smith-Waterman score: 1536; 92.9% identity (94.5% similar) in 238 aa overlap (54-291:343-573) 30 40 50 60 70 80 pF1KB4 SKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRIC :: : . : :.: : .: :.:::: CCDS60 FEDSTSAKLKSRVLRAPLCSTEKDSDLDCPSPFSEKLP-PISPVS------TSGDVCRIC 320 330 340 350 360 90 100 110 120 130 140 pF1KB4 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE 370 380 390 400 410 420 150 160 170 180 190 200 pF1KB4 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV 430 440 450 460 470 480 210 220 230 240 250 260 pF1KB4 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK 490 500 510 520 530 540 270 280 290 pF1KB4 HGYGICHSDTNSSCCTEPEDTGAEIIHV :::::::::::::::::::::::::::: CCDS60 HGYGICHSDTNSSCCTEPEDTGAEIIHV 550 560 570 >-- initn: 547 init1: 515 opt: 527 Z-score: 556.9 bits: 112.0 E(32554): 1.1e-24 Smith-Waterman score: 527; 78.4% identity (86.5% similar) in 111 aa overlap (1-103:1-110) 10 20 30 40 50 60 pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 PAPVSSFSRTSITPSSQDIC-------RICHCEGDDESPLITPC-HCTGSLHFVHQACLQ :::::::::::::::::::: . :: ... .: ... :: .:: CCDS60 PAPVSSFSRTSITPSSQDICSSSAVFSECCH-HSSVQSAVVSKAPHCQSSLTQGLTVTVI 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 QWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWS CCDS60 CKDTLQASKRNSFGSEWAQALKPAKNTKARRTLKFSRSLNDVGEKAQDTSESFAYVERTC 120 130 140 150 160 170 >>CCDS54814.1 MARCH1 gene_id:55016|Hs108|chr4 (289 aa) initn: 1159 init1: 1159 opt: 1246 Z-score: 1316.4 bits: 251.5 E(32554): 5.3e-67 Smith-Waterman score: 1246; 71.2% identity (86.0% similar) in 257 aa overlap (35-291:38-289) 10 20 30 40 50 60 pF1KB4 LHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPV :::. :. :.:::::::.:: ...:: CCDS54 IARNPHRIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAP--- 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCE : :: :. ::.::::::::::::.::::::::.:::.:.::::.::.:::::::::::: CCDS54 RSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEI ::::.:::::::::::::::::::.::::::.:::::::::::::::::::::::::::: CCDS54 LCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPET :::. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.: CCDS54 KQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDT 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 SKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV .:: .::. . : . : . . .:... : :.. : CCDS54 AKK--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV 250 260 270 280 >>CCDS3806.1 MARCH1 gene_id:55016|Hs108|chr4 (272 aa) initn: 1159 init1: 1159 opt: 1190 Z-score: 1258.0 bits: 240.6 E(32554): 9.5e-64 Smith-Waterman score: 1190; 67.8% identity (85.5% similar) in 255 aa overlap (41-291:23-272) 20 30 40 50 60 pF1KB4 IPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS----KAGSPPSASAPAPVSS .........: .:.:: ...:: : CCDS38 MTSSHVCCNFLNMWKKSKISTMYYLNQDAKLSNLFLQASSPTTGTAP---RS 10 20 30 40 70 80 90 100 110 120 pF1KB4 FSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELC :: :. ::.::::::::::::.::::::::.:::.:.::::.::.:::::::::::::: CCDS38 QSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELC 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 KYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ ::.:::::::::::::::::::.::::::.:::::::::::::::::::::::::::::: CCDS38 KYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRTAEEIKQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 GQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSK :. .:.::::::::::::::::::::.:::::::::::::.:::::::::.:::::.:.: CCDS38 GNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAK 170 180 190 200 210 220 250 260 270 280 290 pF1KB4 KNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV : .::. . : . : . . .:... : :.. : CCDS38 K--LEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV 230 240 250 260 270 >>CCDS12202.1 MARCH2 gene_id:51257|Hs108|chr19 (246 aa) initn: 274 init1: 223 opt: 322 Z-score: 346.8 bits: 71.9 E(32554): 5.4e-13 Smith-Waterman score: 322; 29.9% identity (62.0% similar) in 184 aa overlap (64-243:48-225) 40 50 60 70 80 90 pF1KB4 QNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRICHCEGDDESPL .:. :. :::. .::::: :: . : CCDS12 GSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRALDTPSDGPFCRICH-EGANGECL 20 30 40 50 60 70 100 110 120 130 140 150 pF1KB4 ITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERR ..:: :::.: ::..::..:..::.: ::::. :: .: . .:: .: : .:.: CCDS12 LSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKR 80 90 100 110 120 130 160 170 180 190 200 210 pF1KB4 KIMCSVTFHVIAITCVVWSLYVLIDRTAEEIK---QGQATGILEWPFWTKLVVVAIGFTG . :... .. .. : .. . . .... : .:.:.. . : .. . .: CCDS12 TLCCDMVCFLFITPLAAISGWLCLRGAQDHLRLHSQLEAVGLI--ALTIALFTIYVLWT- 140 150 160 170 180 190 220 230 240 250 260 pF1KB4 GLLFMYVQCKVYVQLWKRLKAYNRV-IYVQNCPETSKKNIFEKSPLTEPNFENKHGYGIC :. . .:..: . :.. . :. : . :: CCDS12 -LVSFRYHCQLYSE-WRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKVAEETPV 200 210 220 230 240 270 280 290 pF1KB4 HSDTNSSCCTEPEDTGAEIIHV >>CCDS4141.1 MARCH3 gene_id:115123|Hs108|chr5 (253 aa) initn: 266 init1: 229 opt: 293 Z-score: 316.2 bits: 66.2 E(32554): 2.7e-11 Smith-Waterman score: 293; 31.0% identity (62.0% similar) in 187 aa overlap (57-236:45-222) 30 40 50 60 70 80 pF1KB4 KEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPS---SQDICRIC ::. .:. :: : : .. .:::: CCDS41 DCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRIC 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE : ::... :..::.:::.: .:..::..:..::.: ::::...: .: : .:: .: CCDS41 H-EGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWL 80 90 100 110 120 130 150 160 170 180 190 pF1KB4 KLQMTSSERRKIMCS-VTFHVIAITCVV--W-SLYVLIDRTAEEIKQGQATGILEWPFWT . . :.: .. . : : :. .. : : .:. . .:.:.. . . CCDS41 RNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRL-EAVGLIA--LTV 140 150 160 170 180 190 200 210 220 230 240 250 pF1KB4 KLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPN : .. . .: :. . .:..: . :.: . .::: CCDS41 ALFTIYLFWT--LVSFRYHCRLYNE-WRRTN--QRVILLIPKSVNVPSNQPSLLGLHSVK 200 210 220 230 240 260 270 280 290 pF1KB4 FENKHGYGICHSDTNSSCCTEPEDTGAEIIHV CCDS41 RNSKETVV 250 291 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:02:53 2016 done: Sat Nov 5 06:02:54 2016 Total Scan time: 1.550 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]