Result of FASTA (omim) for pF1KB4828
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4828, 291 aa
  1>>>pF1KB4828 291 - 291 aa - 291 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1806+/-0.000305; mu= 12.0354+/- 0.019
 mean_var=92.9501+/-19.010, 0's: 0 Z-trim(119.2): 75  B-trim: 2716 in 2/56
 Lambda= 0.133030
 statistics sampled from 32924 (33017) to 32924 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.387), width:  16
 Scan time:  4.900

The best scores are:                                      opt bits E(85289)
NP_659458 (OMIM: 613335) E3 ubiquitin-protein liga ( 291) 2010 395.3 7.3e-110
XP_016871383 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 2010 395.3 7.3e-110
XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 291) 2010 395.3 7.3e-110
NP_001002266 (OMIM: 613335) E3 ubiquitin-protein l ( 291) 2010 395.3 7.3e-110
XP_011537794 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1536 304.5 3.1e-82
XP_011537795 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1536 304.5 3.1e-82
XP_011537796 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1536 304.5 3.1e-82
NP_001269795 (OMIM: 613335) E3 ubiquitin-protein l ( 573) 1536 304.5 3.1e-82
XP_005271861 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1536 304.5 3.1e-82
XP_006717767 (OMIM: 613335) PREDICTED: E3 ubiquiti ( 573) 1536 304.5 3.1e-82
XP_016863825 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 285) 1335 265.7 7.1e-71
XP_016863824 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 285) 1335 265.7 7.1e-71
XP_016863823 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 289) 1246 248.7   1e-65
NP_001159845 (OMIM: 613331) E3 ubiquitin-protein l ( 289) 1246 248.7   1e-65
NP_060393 (OMIM: 613331) E3 ubiquitin-protein liga ( 272) 1190 237.9 1.6e-62
XP_011530357 (OMIM: 613331) PREDICTED: E3 ubiquiti ( 545) 1125 225.6 1.6e-58
XP_016882342 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 246)  322 71.3 2.1e-12
NP_057580 (OMIM: 613332) E3 ubiquitin-protein liga ( 246)  322 71.3 2.1e-12
NP_001005415 (OMIM: 613332) E3 ubiquitin-protein l ( 246)  322 71.3 2.1e-12
XP_011526348 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 256)  305 68.0 2.1e-11
XP_011526349 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 256)  305 68.0 2.1e-11
NP_848545 (OMIM: 613333) E3 ubiquitin-protein liga ( 253)  293 65.7   1e-10
XP_016864504 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 154)  268 60.8 1.9e-09
XP_011541431 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280)  267 60.8 3.5e-09
XP_011541432 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280)  267 60.8 3.5e-09
XP_011541433 (OMIM: 613333) PREDICTED: E3 ubiquiti ( 280)  267 60.8 3.5e-09
XP_006722826 (OMIM: 613332) PREDICTED: E3 ubiquiti ( 176)  262 59.7 4.7e-09
NP_001005416 (OMIM: 613332) E3 ubiquitin-protein l ( 176)  262 59.7 4.7e-09
NP_612405 (OMIM: 613336) E3 ubiquitin-protein liga ( 346)  264 60.2 6.3e-09
XP_016864433 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 460)  260 59.5 1.4e-08
NP_065865 (OMIM: 608208) E3 ubiquitin-protein liga ( 410)  259 59.3 1.4e-08
XP_011512238 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 637)  260 59.6 1.8e-08
XP_011512236 (OMIM: 613297) PREDICTED: E3 ubiquiti ( 791)  260 59.7 2.1e-08
NP_005876 (OMIM: 613297) E3 ubiquitin-protein liga ( 910)  260 59.7 2.4e-08
NP_001257589 (OMIM: 613297) E3 ubiquitin-protein l ( 862)  257 59.1 3.4e-08
NP_001096032 (OMIM: 613338) E3 ubiquitin-protein l ( 402)  252 58.0 3.5e-08
XP_005257163 (OMIM: 613337) PREDICTED: probable E3 ( 752)  217 51.4 6.2e-06
NP_001275709 (OMIM: 613337) probable E3 ubiquitin- ( 799)  217 51.4 6.5e-06
XP_005257160 (OMIM: 613337) PREDICTED: probable E3 ( 799)  217 51.4 6.5e-06
XP_011522739 (OMIM: 613337) PREDICTED: probable E3 ( 807)  217 51.4 6.6e-06
NP_689811 (OMIM: 613337) probable E3 ubiquitin-pro ( 808)  217 51.4 6.6e-06
NP_001094345 (OMIM: 613337) probable E3 ubiquitin- ( 808)  217 51.4 6.6e-06
XP_005257159 (OMIM: 613337) PREDICTED: probable E3 ( 824)  217 51.4 6.7e-06
XP_011522738 (OMIM: 613337) PREDICTED: probable E3 ( 825)  217 51.4 6.7e-06
XP_005257157 (OMIM: 613337) PREDICTED: probable E3 ( 825)  217 51.4 6.7e-06
NP_001275708 (OMIM: 613337) probable E3 ubiquitin- ( 846)  217 51.5 6.8e-06
XP_011522737 (OMIM: 613337) PREDICTED: probable E3 ( 862)  217 51.5 6.9e-06
XP_005257155 (OMIM: 613337) PREDICTED: probable E3 ( 862)  217 51.5 6.9e-06
XP_005257152 (OMIM: 613337) PREDICTED: probable E3 ( 863)  217 51.5 6.9e-06
XP_005257153 (OMIM: 613337) PREDICTED: probable E3 ( 863)  217 51.5 6.9e-06


>>NP_659458 (OMIM: 613335) E3 ubiquitin-protein ligase M  (291 aa)
 initn: 2010 init1: 2010 opt: 2010  Z-score: 2093.4  bits: 395.3 E(85289): 7.3e-110
Smith-Waterman score: 2010; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN
              190       200       210       220       230       240

              250       260       270       280       290 
pF1KB4 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
              250       260       270       280       290 

>>XP_016871383 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (291 aa)
 initn: 2010 init1: 2010 opt: 2010  Z-score: 2093.4  bits: 395.3 E(85289): 7.3e-110
Smith-Waterman score: 2010; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN
              190       200       210       220       230       240

              250       260       270       280       290 
pF1KB4 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
              250       260       270       280       290 

>>XP_011537797 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (291 aa)
 initn: 2010 init1: 2010 opt: 2010  Z-score: 2093.4  bits: 395.3 E(85289): 7.3e-110
Smith-Waterman score: 2010; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN
              190       200       210       220       230       240

              250       260       270       280       290 
pF1KB4 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
              250       260       270       280       290 

>>NP_001002266 (OMIM: 613335) E3 ubiquitin-protein ligas  (291 aa)
 initn: 2010 init1: 2010 opt: 2010  Z-score: 2093.4  bits: 395.3 E(85289): 7.3e-110
Smith-Waterman score: 2010; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQN
              190       200       210       220       230       240

              250       260       270       280       290 
pF1KB4 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGAEIIHV
              250       260       270       280       290 

>>XP_011537794 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (573 aa)
 initn: 1526 init1: 1526 opt: 1536  Z-score: 1597.4  bits: 304.5 E(85289): 3.1e-82
Smith-Waterman score: 1536; 92.9% identity (94.5% similar) in 238 aa overlap (54-291:343-573)

            30        40        50        60        70        80   
pF1KB4 SKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRIC
                                     :: : . : :.:  :      .: :.::::
XP_011 FEDSTSAKLKSRVLRAPLCSTEKDSDLDCPSPFSEKLP-PISPVS------TSGDVCRIC
            320       330       340       350              360     

            90       100       110       120       130       140   
pF1KB4 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
         370       380       390       400       410       420     

           150       160       170       180       190       200   
pF1KB4 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
         430       440       450       460       470       480     

           210       220       230       240       250       260   
pF1KB4 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
         490       500       510       520       530       540     

           270       280       290 
pF1KB4 HGYGICHSDTNSSCCTEPEDTGAEIIHV
       ::::::::::::::::::::::::::::
XP_011 HGYGICHSDTNSSCCTEPEDTGAEIIHV
         550       560       570   

>--
 initn: 547 init1: 515 opt: 527  Z-score: 550.8  bits: 110.8 E(85289): 6.1e-24
Smith-Waterman score: 527; 78.4% identity (86.5% similar) in 111 aa overlap (1-103:1-110)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80               90        100       110  
pF1KB4 PAPVSSFSRTSITPSSQDIC-------RICHCEGDDESPLITPC-HCTGSLHFVHQACLQ
       ::::::::::::::::::::       . :: ... .: ...   :: .::         
XP_011 PAPVSSFSRTSITPSSQDICSSSAVFSECCH-HSSVQSAVVSKAPHCQSSLTQGLTVTVI
               70        80        90        100       110         

            120       130       140       150       160       170  
pF1KB4 QWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWS
                                                                   
XP_011 CKDTLQASKRNSFGSEWAQALKPAKNTKARRTLKFSRSLNDVGEKAQDTSESFAYVERTC
     120       130       140       150       160       170         

>>XP_011537795 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (573 aa)
 initn: 1526 init1: 1526 opt: 1536  Z-score: 1597.4  bits: 304.5 E(85289): 3.1e-82
Smith-Waterman score: 1536; 92.9% identity (94.5% similar) in 238 aa overlap (54-291:343-573)

            30        40        50        60        70        80   
pF1KB4 SKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRIC
                                     :: : . : :.:  :      .: :.::::
XP_011 FEDSTSAKLKSRVLRAPLCSTEKDSDLDCPSPFSEKLP-PISPVS------TSGDVCRIC
            320       330       340       350              360     

            90       100       110       120       130       140   
pF1KB4 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
         370       380       390       400       410       420     

           150       160       170       180       190       200   
pF1KB4 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
         430       440       450       460       470       480     

           210       220       230       240       250       260   
pF1KB4 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
         490       500       510       520       530       540     

           270       280       290 
pF1KB4 HGYGICHSDTNSSCCTEPEDTGAEIIHV
       ::::::::::::::::::::::::::::
XP_011 HGYGICHSDTNSSCCTEPEDTGAEIIHV
         550       560       570   

>--
 initn: 547 init1: 515 opt: 527  Z-score: 550.8  bits: 110.8 E(85289): 6.1e-24
Smith-Waterman score: 527; 78.4% identity (86.5% similar) in 111 aa overlap (1-103:1-110)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80               90        100       110  
pF1KB4 PAPVSSFSRTSITPSSQDIC-------RICHCEGDDESPLITPC-HCTGSLHFVHQACLQ
       ::::::::::::::::::::       . :: ... .: ...   :: .::         
XP_011 PAPVSSFSRTSITPSSQDICSSSAVFSECCH-HSSVQSAVVSKAPHCQSSLTQGLTVTVI
               70        80        90        100       110         

            120       130       140       150       160       170  
pF1KB4 QWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWS
                                                                   
XP_011 CKDTLQASKRNSFGSEWAQALKPAKNTKARRTLKFSRSLNDVGEKAQDTSESFAYVERTC
     120       130       140       150       160       170         

>>XP_011537796 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (573 aa)
 initn: 1526 init1: 1526 opt: 1536  Z-score: 1597.4  bits: 304.5 E(85289): 3.1e-82
Smith-Waterman score: 1536; 92.9% identity (94.5% similar) in 238 aa overlap (54-291:343-573)

            30        40        50        60        70        80   
pF1KB4 SKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRIC
                                     :: : . : :.:  :      .: :.::::
XP_011 FEDSTSAKLKSRVLRAPLCSTEKDSDLDCPSPFSEKLP-PISPVS------TSGDVCRIC
            320       330       340       350              360     

            90       100       110       120       130       140   
pF1KB4 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
         370       380       390       400       410       420     

           150       160       170       180       190       200   
pF1KB4 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
         430       440       450       460       470       480     

           210       220       230       240       250       260   
pF1KB4 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
         490       500       510       520       530       540     

           270       280       290 
pF1KB4 HGYGICHSDTNSSCCTEPEDTGAEIIHV
       ::::::::::::::::::::::::::::
XP_011 HGYGICHSDTNSSCCTEPEDTGAEIIHV
         550       560       570   

>--
 initn: 547 init1: 515 opt: 527  Z-score: 550.8  bits: 110.8 E(85289): 6.1e-24
Smith-Waterman score: 527; 78.4% identity (86.5% similar) in 111 aa overlap (1-103:1-110)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80               90        100       110  
pF1KB4 PAPVSSFSRTSITPSSQDIC-------RICHCEGDDESPLITPC-HCTGSLHFVHQACLQ
       ::::::::::::::::::::       . :: ... .: ...   :: .::         
XP_011 PAPVSSFSRTSITPSSQDICSSSAVFSECCH-HSSVQSAVVSKAPHCQSSLTQGLTVTVI
               70        80        90        100       110         

            120       130       140       150       160       170  
pF1KB4 QWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWS
                                                                   
XP_011 CKDTLQASKRNSFGSEWAQALKPAKNTKARRTLKFSRSLNDVGEKAQDTSESFAYVERTC
     120       130       140       150       160       170         

>>NP_001269795 (OMIM: 613335) E3 ubiquitin-protein ligas  (573 aa)
 initn: 1526 init1: 1526 opt: 1536  Z-score: 1597.4  bits: 304.5 E(85289): 3.1e-82
Smith-Waterman score: 1536; 92.9% identity (94.5% similar) in 238 aa overlap (54-291:343-573)

            30        40        50        60        70        80   
pF1KB4 SKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRIC
                                     :: : . : :.:  :      .: :.::::
NP_001 FEDSTSAKLKSRVLRAPLCSTEKDSDLDCPSPFSEKLP-PISPVS------TSGDVCRIC
            320       330       340       350              360     

            90       100       110       120       130       140   
pF1KB4 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
         370       380       390       400       410       420     

           150       160       170       180       190       200   
pF1KB4 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
         430       440       450       460       470       480     

           210       220       230       240       250       260   
pF1KB4 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
         490       500       510       520       530       540     

           270       280       290 
pF1KB4 HGYGICHSDTNSSCCTEPEDTGAEIIHV
       ::::::::::::::::::::::::::::
NP_001 HGYGICHSDTNSSCCTEPEDTGAEIIHV
         550       560       570   

>--
 initn: 547 init1: 515 opt: 527  Z-score: 550.8  bits: 110.8 E(85289): 6.1e-24
Smith-Waterman score: 527; 78.4% identity (86.5% similar) in 111 aa overlap (1-103:1-110)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80               90        100       110  
pF1KB4 PAPVSSFSRTSITPSSQDIC-------RICHCEGDDESPLITPC-HCTGSLHFVHQACLQ
       ::::::::::::::::::::       . :: ... .: ...   :: .::         
NP_001 PAPVSSFSRTSITPSSQDICSSSAVFSECCH-HSSVQSAVVSKAPHCQSSLTQGLTVTVI
               70        80        90        100       110         

            120       130       140       150       160       170  
pF1KB4 QWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWS
                                                                   
NP_001 CKDTLQASKRNSFGSEWAQALKPAKNTKARRTLKFSRSLNDVGEKAQDTSESFAYVERTC
     120       130       140       150       160       170         

>>XP_005271861 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (573 aa)
 initn: 1526 init1: 1526 opt: 1536  Z-score: 1597.4  bits: 304.5 E(85289): 3.1e-82
Smith-Waterman score: 1536; 92.9% identity (94.5% similar) in 238 aa overlap (54-291:343-573)

            30        40        50        60        70        80   
pF1KB4 SKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRIC
                                     :: : . : :.:  :      .: :.::::
XP_005 FEDSTSAKLKSRVLRAPLCSTEKDSDLDCPSPFSEKLP-PISPVS------TSGDVCRIC
            320       330       340       350              360     

            90       100       110       120       130       140   
pF1KB4 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
         370       380       390       400       410       420     

           150       160       170       180       190       200   
pF1KB4 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
         430       440       450       460       470       480     

           210       220       230       240       250       260   
pF1KB4 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
         490       500       510       520       530       540     

           270       280       290 
pF1KB4 HGYGICHSDTNSSCCTEPEDTGAEIIHV
       ::::::::::::::::::::::::::::
XP_005 HGYGICHSDTNSSCCTEPEDTGAEIIHV
         550       560       570   

>--
 initn: 547 init1: 515 opt: 527  Z-score: 550.8  bits: 110.8 E(85289): 6.1e-24
Smith-Waterman score: 527; 78.4% identity (86.5% similar) in 111 aa overlap (1-103:1-110)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80               90        100       110  
pF1KB4 PAPVSSFSRTSITPSSQDIC-------RICHCEGDDESPLITPC-HCTGSLHFVHQACLQ
       ::::::::::::::::::::       . :: ... .: ...   :: .::         
XP_005 PAPVSSFSRTSITPSSQDICSSSAVFSECCH-HSSVQSAVVSKAPHCQSSLTQGLTVTVI
               70        80        90        100       110         

            120       130       140       150       160       170  
pF1KB4 QWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWS
                                                                   
XP_005 CKDTLQASKRNSFGSEWAQALKPAKNTKARRTLKFSRSLNDVGEKAQDTSESFAYVERTC
     120       130       140       150       160       170         

>>XP_006717767 (OMIM: 613335) PREDICTED: E3 ubiquitin-pr  (573 aa)
 initn: 1526 init1: 1526 opt: 1536  Z-score: 1597.4  bits: 304.5 E(85289): 3.1e-82
Smith-Waterman score: 1536; 92.9% identity (94.5% similar) in 238 aa overlap (54-291:343-573)

            30        40        50        60        70        80   
pF1KB4 SKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRIC
                                     :: : . : :.:  :      .: :.::::
XP_006 FEDSTSAKLKSRVLRAPLCSTEKDSDLDCPSPFSEKLP-PISPVS------TSGDVCRIC
            320       330       340       350              360     

            90       100       110       120       130       140   
pF1KB4 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWE
         370       380       390       400       410       420     

           150       160       170       180       190       200   
pF1KB4 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGQATGILEWPFWTKLVV
         430       440       450       460       470       480     

           210       220       230       240       250       260   
pF1KB4 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAIGFTGGLLFMYVQCKVYVQLWKRLKAYNRVIYVQNCPETSKKNIFEKSPLTEPNFENK
         490       500       510       520       530       540     

           270       280       290 
pF1KB4 HGYGICHSDTNSSCCTEPEDTGAEIIHV
       ::::::::::::::::::::::::::::
XP_006 HGYGICHSDTNSSCCTEPEDTGAEIIHV
         550       560       570   

>--
 initn: 547 init1: 515 opt: 527  Z-score: 550.8  bits: 110.8 E(85289): 6.1e-24
Smith-Waterman score: 527; 78.4% identity (86.5% similar) in 111 aa overlap (1-103:1-110)

               10        20        30        40        50        60
pF1KB4 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNISKAGSPPSASA
               10        20        30        40        50        60

               70        80               90        100       110  
pF1KB4 PAPVSSFSRTSITPSSQDIC-------RICHCEGDDESPLITPC-HCTGSLHFVHQACLQ
       ::::::::::::::::::::       . :: ... .: ...   :: .::         
XP_006 PAPVSSFSRTSITPSSQDICSSSAVFSECCH-HSSVQSAVVSKAPHCQSSLTQGLTVTVI
               70        80        90        100       110         

            120       130       140       150       160       170  
pF1KB4 QWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWS
                                                                   
XP_006 CKDTLQASKRNSFGSEWAQALKPAKNTKARRTLKFSRSLNDVGEKAQDTSESFAYVERTC
     120       130       140       150       160       170         




291 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 06:02:54 2016 done: Sat Nov  5 06:02:55 2016
 Total Scan time:  4.900 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com