FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4832, 422 aa 1>>>pF1KB4832 422 - 422 aa - 422 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6394+/-0.000832; mu= 15.6026+/- 0.050 mean_var=70.0637+/-13.739, 0's: 0 Z-trim(107.7): 21 B-trim: 475 in 1/50 Lambda= 0.153224 statistics sampled from 9693 (9713) to 9693 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.298), width: 16 Scan time: 2.690 The best scores are: opt bits E(32554) CCDS11034.1 P2RX5 gene_id:5026|Hs108|chr17 ( 422) 2863 641.9 3.4e-184 CCDS56015.1 P2RX5 gene_id:5026|Hs108|chr17 ( 421) 2841 637.1 9.8e-183 CCDS56014.1 P2RX5 gene_id:5026|Hs108|chr17 ( 398) 2092 471.5 6.5e-133 CCDS11035.1 P2RX5 gene_id:5026|Hs108|chr17 ( 397) 2070 466.6 1.9e-131 CCDS9214.1 P2RX4 gene_id:5025|Hs108|chr12 ( 388) 1196 273.4 2.7e-73 CCDS13788.2 P2RX6 gene_id:9127|Hs108|chr22 ( 441) 1106 253.5 2.9e-67 CCDS58282.1 P2RX4 gene_id:5025|Hs108|chr12 ( 404) 1086 249.1 5.8e-66 CCDS11040.1 P2RX1 gene_id:5023|Hs108|chr17 ( 399) 1016 233.6 2.6e-61 CCDS31932.1 P2RX2 gene_id:22953|Hs108|chr12 ( 404) 998 229.6 4.1e-60 CCDS31931.1 P2RX2 gene_id:22953|Hs108|chr12 ( 471) 998 229.7 4.7e-60 CCDS31930.1 P2RX2 gene_id:22953|Hs108|chr12 ( 497) 998 229.7 4.9e-60 CCDS73548.1 P2RX2 gene_id:22953|Hs108|chr12 ( 349) 994 228.7 6.7e-60 CCDS54504.1 P2RX6 gene_id:9127|Hs108|chr22 ( 415) 981 225.9 5.7e-59 CCDS7953.1 P2RX3 gene_id:5024|Hs108|chr11 ( 397) 843 195.4 8.4e-50 CCDS9213.1 P2RX7 gene_id:5027|Hs108|chr12 ( 595) 788 183.3 5.4e-46 CCDS31935.1 P2RX2 gene_id:22953|Hs108|chr12 ( 379) 696 162.9 4.9e-40 CCDS31933.1 P2RX2 gene_id:22953|Hs108|chr12 ( 447) 696 162.9 5.6e-40 CCDS31934.1 P2RX2 gene_id:22953|Hs108|chr12 ( 399) 634 149.2 6.8e-36 >>CCDS11034.1 P2RX5 gene_id:5026|Hs108|chr17 (422 aa) initn: 2863 init1: 2863 opt: 2863 Z-score: 3420.4 bits: 641.9 E(32554): 3.4e-184 Smith-Waterman score: 2863; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422) 10 20 30 40 50 60 pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 370 380 390 400 410 420 pF1KB4 ST :: CCDS11 ST >>CCDS56015.1 P2RX5 gene_id:5026|Hs108|chr17 (421 aa) initn: 1480 init1: 1480 opt: 2841 Z-score: 3394.2 bits: 637.1 E(32554): 9.8e-183 Smith-Waterman score: 2841; 99.5% identity (99.8% similar) in 422 aa overlap (1-422:1-421) 10 20 30 40 50 60 pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW :::::::::::::::::::::::: .:::::::::::::::::::::::::::::::::: CCDS56 FLKEAEDFTIFIKNHIRFPKFNFS-NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB4 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 360 370 380 390 400 410 pF1KB4 ST :: CCDS56 ST 420 >>CCDS56014.1 P2RX5 gene_id:5026|Hs108|chr17 (398 aa) initn: 2092 init1: 2092 opt: 2092 Z-score: 2499.7 bits: 471.5 E(32554): 6.5e-133 Smith-Waterman score: 2647; 94.3% identity (94.3% similar) in 422 aa overlap (1-422:1-398) 10 20 30 40 50 60 pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE :::::::::::::::::::::::::::::::::::: CCDS56 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ------------------------ 70 80 90 130 140 150 160 170 180 pF1KB4 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 340 350 360 370 380 390 pF1KB4 ST :: CCDS56 ST >>CCDS11035.1 P2RX5 gene_id:5026|Hs108|chr17 (397 aa) initn: 2096 init1: 1480 opt: 2070 Z-score: 2473.5 bits: 466.6 E(32554): 1.9e-131 Smith-Waterman score: 2625; 93.8% identity (94.1% similar) in 422 aa overlap (1-422:1-397) 10 20 30 40 50 60 pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE :::::::::::::::::::::::::::::::::::: CCDS11 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ------------------------ 70 80 90 130 140 150 160 170 180 pF1KB4 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW :::::::::::::::::::::::: .:::::::::::::::::::::::::::::::::: CCDS11 FLKEAEDFTIFIKNHIRFPKFNFS-NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 340 350 360 370 380 390 pF1KB4 ST :: CCDS11 ST >>CCDS9214.1 P2RX4 gene_id:5025|Hs108|chr12 (388 aa) initn: 1105 init1: 407 opt: 1196 Z-score: 1429.5 bits: 273.4 E(32554): 2.7e-73 Smith-Waterman score: 1246; 50.3% identity (74.0% similar) in 392 aa overlap (4-367:2-388) 10 20 30 40 50 pF1KB4 MGQAGC-KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVD ::: .: ::.: : . :. ...::::. : .: ::::.. :::. .::::..: CCDS92 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETD 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 TSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCA :. :.: ::::::: :::: :: ::::::::::::: :: .::.::.:.: :: :..: CCDS92 -SVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 ENEGIPDGA--CSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR- : :::.. :..:..: :: : : .:::.::::. .. .. :::. ::::.: ... CCDS92 E---IPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK-TCEVAAWCPVEDDTHV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 PEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCPIFRLG :. ::: ::.::...::.: .::::::: :.. ..:::: . : . .::::::: CCDS92 PQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 SVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNK-LSKSVSSGYN .... :: .:::.:.:::..::...:.:.::.::: : :.::: :::.. . ..:: ::: CCDS92 KIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYN 240 250 260 270 280 290 300 310 320 330 pF1KB4 FRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-GAF---------------------FC ::::.:::: :: : :::.::::::::..: :: : : .: CCDS92 FRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLC 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB4 DLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQEL :....: .::: .::.:::. :. :.. :. CCDS92 DIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ 360 370 380 400 410 420 pF1KB4 QEPPEAKRGSSSQKGNGSVCPQLLEPHRST >>CCDS13788.2 P2RX6 gene_id:9127|Hs108|chr22 (441 aa) initn: 858 init1: 647 opt: 1106 Z-score: 1321.1 bits: 253.5 E(32554): 2.9e-67 Smith-Waterman score: 1156; 44.1% identity (69.6% similar) in 424 aa overlap (2-395:9-423) 10 20 30 40 50 pF1KB4 MGQAGCKGLCLS--LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLI :. : : . :.::::::::...: .:: : :::: .:..:.: :..: CCDS13 MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 KKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTP :::::. : : ..:::.:::. :. ..::.:.:::::.: : :::::::.:::..::: CCDS13 KKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 NQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPL : :. : :. ..: . : : :: ::. : ..:::::.:. .. : ::::..:::. CCDS13 AQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHR-TCEIWSWCPV 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 ETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCP :.. : .:.: .:..::.:::: . : ::::::::.... : ...: :.. :. . ::: CCDS13 ESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 IFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVS .::.:... ::. :.:.:: :: .:: ..:.:::: . : : ::::: .:..: CCDS13 VFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEK------ 240 250 260 270 280 290 300 310 320 pF1KB4 SGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK---------------GA------ .:::: : .. . ::: :::.: ::::::..:.:. :: CCDS13 -SYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVV 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB4 -FFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDE---ASGLGLSEQL--TSGPGL :::::.:.:. .. .:: ::::... . ... . : :: :.: : .:.:. CCDS13 TFFCDLLLLYVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRSSAPAP 360 370 380 390 400 410 390 400 410 420 pF1KB4 LGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST . .. : : CCDS13 TATAAGSQTQTPGWPCPSSDTHLPTHSGSL 420 430 440 >>CCDS58282.1 P2RX4 gene_id:5025|Hs108|chr12 (404 aa) initn: 1095 init1: 407 opt: 1086 Z-score: 1297.8 bits: 249.1 E(32554): 5.8e-66 Smith-Waterman score: 1205; 48.3% identity (71.1% similar) in 408 aa overlap (4-367:2-404) 10 20 30 40 pF1KB4 MGQAGC-KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLV-------------- ::: .: ::.: : . :. ...::::. : .: ::::.. CCDS58 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGCYHPHLAEVEMES 10 20 30 40 50 50 60 70 80 90 100 pF1KB4 --VWVFLIKKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFV :::. .::::..: :. :.: ::::::: :::: :: ::::::::::::: :: .:: CCDS58 PRRWVFVWEKGYQETD-SVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 VTNLIVTPNQRQNVCAENEGIPDGA--CSKDSDCHAGEAVTAGNGVKTGRCLRRENLARG .::.:.: :: :..: : :::.. :..:..: :: : : .:::.::::. .. .. CCDS58 MTNVILTMNQTQGLCPE---IPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK- 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB4 TCEIFAWCPLETSSR-PEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSC :::. ::::.: ... :. ::: ::.::...::.: .::::::: :.. ..:::: CCDS58 TCEVAAWCPVEDDTHVPQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSC 180 190 200 210 220 230 230 240 250 260 270 pF1KB4 HFGPK-NHYCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFS . : . .:::::::.... :: .:::.:.:::..::...:.:.::.::: : :.::: CCDS58 IYDAKTDPFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFR 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB4 RLDNK-LSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-GAF------- :::.. . ..:: :::::::.:::: :: : :::.::::::::..: :: : : CCDS58 RLDTRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMI 300 310 320 330 340 350 340 350 360 370 pF1KB4 --------------FCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQ .::....: .::: .::.:::. :. :.. :. CCDS58 NIGSGLALLGMATVLCDIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ 360 370 380 390 400 380 390 400 410 420 pF1KB4 LTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST >>CCDS11040.1 P2RX1 gene_id:5023|Hs108|chr17 (399 aa) initn: 801 init1: 236 opt: 1016 Z-score: 1214.2 bits: 233.6 E(32554): 2.6e-61 Smith-Waterman score: 1065; 41.6% identity (72.8% similar) in 394 aa overlap (13-379:13-398) 10 20 30 40 50 60 pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT ::.: : ..:...:::::...::.: .:.:.. :::: .:::: ... CCDS11 MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQ-TSS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE .: :.: .:.::.: :. :: ..:::::::.::::.: : :.::.::::.: :. ::: CCDS11 GLISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAE 60 70 80 90 100 110 130 140 150 160 170 pF1KB4 N-EGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-PE . :: : :..:: : :.: ..:..::.:. .. .. :::::.:::.:... :. CCDS11 HPEG---GICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVK-TCEIFGWCPVEVDDDIPR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 EPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSV .:.:::.::.:::: : ::.:. .. :... . . .:.: : : ::.:.:: : CCDS11 PALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 IRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRF .. .:..:. .: .:::.::.:.:.:::: . .:.: : : : .. :..: :.:::: CCDS11 VQESGQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEE--KNLSPGFNFRF 240 250 260 270 280 290 300 310 320 330 pF1KB4 ARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-GAF---------------------FCDLV ::.. . :...: :.:..:::::..:.:: : : .:::. CCDS11 ARHFVEN-GTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLL 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB4 LIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEA--SGLGLSEQLTSGPGLLGMPEQQELQ :.... ::..:..::.. .. . .. : . : : :::.:.. . CCDS11 LLHILPKRHYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS 360 370 380 390 400 410 420 pF1KB4 EPPEAKRGSSSQKGNGSVCPQLLEPHRST >>CCDS31932.1 P2RX2 gene_id:22953|Hs108|chr12 (404 aa) initn: 964 init1: 632 opt: 998 Z-score: 1192.7 bits: 229.6 E(32554): 4.1e-60 Smith-Waterman score: 1020; 42.8% identity (70.2% similar) in 369 aa overlap (10-354:21-381) 10 20 30 40 pF1KB4 MGQAGCKGLCLS-LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWV : : :.::.: : ....:...:.::: .: :: :.: .: CCDS31 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 FLIKKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLI :...:.::. .:. .:..::::::.. ::. ...::: .:: : .: .:: ..: . CCDS31 FIVQKSYQESETGPESSIITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVE 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 VTPNQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAW .: .: :..: :. . ...: .:.:: ::: :::..::::. . :::.:.: CCDS31 ATHSQTQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGW 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB4 CPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH- ::.: .. . . : .:::.::: :..:::.:::.:. : : ..:: : : . CCDS31 CPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB4 YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSK :::::.:: ... :: .: ..: .:::::. :.:.:::: ::::.:.::: ::: : CCDS31 YCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVP 240 250 260 270 280 290 290 300 310 320 pF1KB4 SVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-------------------- . :::::::::.::. :. :::.::::::.::.:.:. CCDS31 A-SSGYNFRFAKYYK-INGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSV 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB4 --GAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLG :.:.:: .:. ...: . : ::.... CCDS31 GVGSFLCDWILLTFMNKNKVYSHKKFDKMVDTPASEPAQASTPTDPKGLAQL 360 370 380 390 400 >>CCDS31931.1 P2RX2 gene_id:22953|Hs108|chr12 (471 aa) initn: 964 init1: 632 opt: 998 Z-score: 1191.6 bits: 229.7 E(32554): 4.7e-60 Smith-Waterman score: 1037; 39.1% identity (66.2% similar) in 435 aa overlap (10-420:21-437) 10 20 30 40 pF1KB4 MGQAGCKGLCLS-LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWV : : :.::.: : ....:...:.::: .: :: :.: .: CCDS31 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 FLIKKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLI :...:.::. .:. .:..::::::.. ::. ...::: .:: : .: .:: ..: . CCDS31 FIVQKSYQESETGPESSIITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVE 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 VTPNQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAW .: .: :..: :. . ...: .:.:: ::: :::..::::. . :::.:.: CCDS31 ATHSQTQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGW 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB4 CPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH- ::.: .. . . : .:::.::: :..:::.:::.:. : : ..:: : : . CCDS31 CPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDL 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB4 YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSK :::::.:: ... :: .: ..: .:::::. :.:.:::: ::::.:.::: ::: : CCDS31 YCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HV 240 250 260 270 280 290 290 300 310 320 pF1KB4 SVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-------------------- .:::::::::.::. :. :::.::::::.::.:.:. CCDS31 PASSGYNFRFAKYYK-INGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSV 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB4 --GAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLG :.:.:: .:. ...: . : ::...: . . . . :.. : ..: : CCDS31 GVGSFLCDWILLTFMNKNKVYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPG 360 370 380 390 400 390 400 410 420 pF1KB4 MPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST ... :: ...:. .:. : . : : CCDS31 HRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 410 420 430 440 450 460 CCDS31 TDPKGLAQL 470 422 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:33:30 2016 done: Fri Nov 4 20:33:30 2016 Total Scan time: 2.690 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]