Result of FASTA (omim) for pF1KB4846
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4846, 480 aa
  1>>>pF1KB4846 480 - 480 aa - 480 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.8285+/-0.000362; mu= -2.2299+/- 0.022
 mean_var=251.6268+/-52.944, 0's: 0 Z-trim(121.3): 41  B-trim: 288 in 1/53
 Lambda= 0.080853
 statistics sampled from 37794 (37835) to 37794 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.444), width:  16
 Scan time:  8.450

The best scores are:                                      opt bits E(85289)
NP_001745 (OMIM: 151385,601399) runt-related trans ( 480) 3253 392.5 1.4e-108
XP_011528068 (OMIM: 151385,601399) PREDICTED: runt ( 480) 3253 392.5 1.4e-108
XP_011528069 (OMIM: 151385,601399) PREDICTED: runt ( 467) 3022 365.5 1.8e-100
NP_001001890 (OMIM: 151385,601399) runt-related tr ( 453) 3020 365.3 2.1e-100
XP_005261125 (OMIM: 151385,601399) PREDICTED: runt ( 468) 3020 365.3 2.1e-100
XP_016883976 (OMIM: 151385,601399) PREDICTED: runt ( 429) 2896 350.8 4.5e-96
NP_001265407 (OMIM: 119600,156510,600211) runt-rel ( 485) 1913 236.1 1.6e-61
NP_001015051 (OMIM: 119600,156510,600211) runt-rel ( 499) 1913 236.2 1.7e-61
XP_011513264 (OMIM: 119600,156510,600211) PREDICTE ( 567) 1913 236.2 1.8e-61
XP_011528072 (OMIM: 151385,601399) PREDICTED: runt ( 277) 1810 224.0 4.3e-58
NP_001116079 (OMIM: 151385,601399) runt-related tr ( 250) 1577 196.8   6e-50
XP_011528070 (OMIM: 151385,601399) PREDICTED: runt ( 403) 1451 182.2 2.3e-45
XP_005261126 (OMIM: 151385,601399) PREDICTED: runt ( 416) 1451 182.2 2.4e-45
XP_016866881 (OMIM: 119600,156510,600211) PREDICTE ( 528) 1242 157.9 6.3e-38
XP_016866880 (OMIM: 119600,156510,600211) PREDICTE ( 592) 1242 157.9 6.9e-38
XP_011513262 (OMIM: 119600,156510,600211) PREDICTE ( 610) 1242 157.9 7.1e-38
NP_001019801 (OMIM: 119600,156510,600211) runt-rel ( 521) 1232 156.7 1.4e-37
XP_011513263 (OMIM: 119600,156510,600211) PREDICTE ( 589) 1232 156.8 1.5e-37
XP_011513266 (OMIM: 119600,156510,600211) PREDICTE ( 508) 1223 155.7 2.8e-37
XP_016866882 (OMIM: 119600,156510,600211) PREDICTE ( 438) 1208 153.9 8.5e-37
XP_011513267 (OMIM: 119600,156510,600211) PREDICTE ( 416) 1199 152.8 1.7e-36
NP_001026850 (OMIM: 600210) runt-related transcrip ( 429) 1087 139.8 1.5e-32
XP_005246081 (OMIM: 600210) PREDICTED: runt-relate ( 429) 1087 139.8 1.5e-32
NP_001307601 (OMIM: 600210) runt-related transcrip ( 429) 1087 139.8 1.5e-32
NP_004341 (OMIM: 600210) runt-related transcriptio ( 415) 1083 139.3   2e-32
XP_011540653 (OMIM: 600210) PREDICTED: runt-relate ( 376)  938 122.3 2.3e-27
XP_011513265 (OMIM: 119600,156510,600211) PREDICTE ( 552)  873 114.9 5.9e-25
XP_006715295 (OMIM: 119600,156510,600211) PREDICTE ( 449)  870 114.5 6.4e-25
XP_011513268 (OMIM: 119600,156510,600211) PREDICTE ( 386)  865 113.8 8.5e-25
XP_016866885 (OMIM: 119600,156510,600211) PREDICTE ( 276)  856 112.7 1.4e-24
XP_016866883 (OMIM: 119600,156510,600211) PREDICTE ( 358)  856 112.8 1.7e-24
XP_016866884 (OMIM: 119600,156510,600211) PREDICTE ( 338)  840 110.9 5.8e-24
XP_016858159 (OMIM: 600210) PREDICTED: runt-relate ( 162)  693 93.5 4.7e-19


>>NP_001745 (OMIM: 151385,601399) runt-related transcrip  (480 aa)
 initn: 3253 init1: 3253 opt: 3253  Z-score: 2070.2  bits: 392.5 E(85289): 1.4e-108
Smith-Waterman score: 3253; 99.8% identity (99.8% similar) in 480 aa overlap (1-480:1-480)

               10        20        30        40        50        60
pF1KB4 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 HHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPAT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 PISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 TSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 GERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
              430       440       450       460       470       480

>>XP_011528068 (OMIM: 151385,601399) PREDICTED: runt-rel  (480 aa)
 initn: 3253 init1: 3253 opt: 3253  Z-score: 2070.2  bits: 392.5 E(85289): 1.4e-108
Smith-Waterman score: 3253; 99.8% identity (99.8% similar) in 480 aa overlap (1-480:1-480)

               10        20        30        40        50        60
pF1KB4 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 HHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPAT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 PISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 TSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 GERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
              430       440       450       460       470       480

>>XP_011528069 (OMIM: 151385,601399) PREDICTED: runt-rel  (467 aa)
 initn: 3021 init1: 3021 opt: 3022  Z-score: 1924.8  bits: 365.5 E(85289): 1.8e-100
Smith-Waterman score: 3121; 97.1% identity (97.1% similar) in 480 aa overlap (1-480:1-467)

               10        20        30        40        50        60
pF1KB4 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPLGA
       :::::::::::::::::::             ::::::::::::::::::::::: ::::
XP_011 MASDSIFESFPSYPQCFMR-------------DASTSRRFTPPSTALSPGKMSEALPLGA
               10                     20        30        40       

               70        80        90       100       110       120
pF1KB4 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA
        50        60        70        80        90       100       

              130       140       150       160       170       180
pF1KB4 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
       110       120       130       140       150       160       

              190       200       210       220       230       240
pF1KB4 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP
       170       180       190       200       210       220       

              250       260       270       280       290       300
pF1KB4 HHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPAT
       230       240       250       260       270       280       

              310       320       330       340       350       360
pF1KB4 PISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPV
       290       300       310       320       330       340       

              370       380       390       400       410       420
pF1KB4 TSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVG
       350       360       370       380       390       400       

              430       440       450       460       470       480
pF1KB4 GERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       410       420       430       440       450       460       

>>NP_001001890 (OMIM: 151385,601399) runt-related transc  (453 aa)
 initn: 3020 init1: 3020 opt: 3020  Z-score: 1923.7  bits: 365.3 E(85289): 2.1e-100
Smith-Waterman score: 3020; 99.8% identity (99.8% similar) in 448 aa overlap (33-480:6-453)

             10        20        30        40        50        60  
pF1KB4 SDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPLGAPD
                                     ::::::::::::::::::::::: ::::::
NP_001                          MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPD
                                        10        20        30     

             70        80        90       100       110       120  
pF1KB4 AGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALG
          40        50        60        70        80        90     

            130       140       150       160       170       180  
pF1KB4 DVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTN
         100       110       120       130       140       150     

            190       200       210       220       230       240  
pF1KB4 PPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHH
         160       170       180       190       200       210     

            250       260       270       280       290       300  
pF1KB4 PAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPI
         220       230       240       250       260       270     

            310       320       330       340       350       360  
pF1KB4 SPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTS
         280       290       300       310       320       330     

            370       380       390       400       410       420  
pF1KB4 GIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGE
         340       350       360       370       380       390     

            430       440       450       460       470       480
pF1KB4 RSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
         400       410       420       430       440       450   

>>XP_005261125 (OMIM: 151385,601399) PREDICTED: runt-rel  (468 aa)
 initn: 3020 init1: 3020 opt: 3020  Z-score: 1923.5  bits: 365.3 E(85289): 2.1e-100
Smith-Waterman score: 3020; 99.8% identity (99.8% similar) in 448 aa overlap (33-480:21-468)

             10        20        30        40        50        60  
pF1KB4 SDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPLGAPD
                                     ::::::::::::::::::::::: ::::::
XP_005           MPAAPRGPAQGEAAARTRSRDASTSRRFTPPSTALSPGKMSEALPLGAPD
                         10        20        30        40        50

             70        80        90       100       110       120  
pF1KB4 AGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALG
               60        70        80        90       100       110

            130       140       150       160       170       180  
pF1KB4 DVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTN
              120       130       140       150       160       170

            190       200       210       220       230       240  
pF1KB4 PPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHH
              180       190       200       210       220       230

            250       260       270       280       290       300  
pF1KB4 PAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPI
              240       250       260       270       280       290

            310       320       330       340       350       360  
pF1KB4 SPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTS
              300       310       320       330       340       350

            370       380       390       400       410       420  
pF1KB4 GIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGE
              360       370       380       390       400       410

            430       440       450       460       470       480
pF1KB4 RSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
              420       430       440       450       460        

>>XP_016883976 (OMIM: 151385,601399) PREDICTED: runt-rel  (429 aa)
 initn: 2896 init1: 2896 opt: 2896  Z-score: 1845.8  bits: 350.8 E(85289): 4.5e-96
Smith-Waterman score: 2896; 99.8% identity (99.8% similar) in 429 aa overlap (52-480:1-429)

              30        40        50        60        70        80 
pF1KB4 ILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPLGAPDAGAALAGKLRSGDRSMVEV
                                     :::: :::::::::::::::::::::::::
XP_016                               MSEALPLGAPDAGAALAGKLRSGDRSMVEV
                                             10        20        30

              90       100       110       120       130       140 
pF1KB4 LADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYS
               40        50        60        70        80        90

             150       160       170       180       190       200 
pF1KB4 AELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPR
              100       110       120       130       140       150

             210       220       230       240       250       260 
pF1KB4 EPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNP
              160       170       180       190       200       210

             270       280       290       300       310       320 
pF1KB4 QPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRL
              220       230       240       250       260       270

             330       340       350       360       370       380 
pF1KB4 STAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYL
              280       290       300       310       320       330

             390       400       410       420       430       440 
pF1KB4 PPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSAL
              340       350       360       370       380       390

             450       460       470       480
pF1KB4 LNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       :::::::::::::::::::::::::::::::::::::::
XP_016 LNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
              400       410       420         

>>NP_001265407 (OMIM: 119600,156510,600211) runt-related  (485 aa)
 initn: 1554 init1: 880 opt: 1913  Z-score: 1225.4  bits: 236.1 E(85289): 1.6e-61
Smith-Waterman score: 1963; 62.9% identity (80.3% similar) in 493 aa overlap (33-480:6-485)

             10        20        30        40        50            
pF1KB4 SDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPL----
                                     : ::::::.:::..:.:::::..::.    
NP_001                          MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
                                        10        20        30     

                                      60        70          80     
pF1KB4 -------------------------------GAPDAGAALAGKLRS--GDRSMVEVLADH
                                      .:  :.:: . .::    .:.:::..:::
NP_001 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
          40        50        60        70        80        90     

          90       100       110       120       130       140     
pF1KB4 PGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELR
       :.::::::::::::::::.:::::::::.::::::::.:::::.::::::::::::::::
NP_001 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
         100       110       120       130       140       150     

         150       160       170       180       190       200     
pF1KB4 NATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRR
       ::.:.::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
         160       170       180       190       200       210     

         210       220       230       240       250        260    
pF1KB4 HRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHS-TAFNPQPQ
       ::::::: .:: :: ::.:::.: .. . .:::.    .:  ::: ::: . . :::: :
NP_001 HRQKLDD-SKP-SL-FSDRLSDLGRIPHPSMRVG----VPPQNPRPSLNSAPSPFNPQGQ
         220          230       240           250       260        

          270       280        290       300       310       320   
pF1KB4 SQMQDTRQIQPSPPWSYDQSY-QYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLST
       ::. : :: : :::::::::: .::....:::.: .::.:  :..:. ... ..  :.: 
NP_001 SQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAIT-DVPRRISG
      270       280       290       300       310        320       

           330       340            350       360       370        
pF1KB4 APDLTAFSDPRQFPALPSI-----SDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYH
       : .:  ::::::::.. :.     :.::::::..:::.: :::::...::::   .:.::
NP_001 ASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTP-PVTSGMSLGMSA---TTHYH
       330       340       350       360        370          380   

      380       390       400       410        420       430       
pF1KB4 TYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMV-GGERSPPRILPPCTNAST
       ::::::::::::.:.::::.::  : ::::.:.::::: :: ::.::: :.:::::..:.
NP_001 TYLPPPYPGSSQSQSGPFQTSSTPY-LYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSN
           390       400        410       420       430       440  

       440       450       460       470       480
pF1KB4 GSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       ::.::::.::::.: :.:.::::.::: .  :.:..:.:::::
NP_001 GSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
            450       460       470       480     

>>NP_001015051 (OMIM: 119600,156510,600211) runt-related  (499 aa)
 initn: 1554 init1: 880 opt: 1913  Z-score: 1225.2  bits: 236.2 E(85289): 1.7e-61
Smith-Waterman score: 1965; 60.4% identity (77.5% similar) in 525 aa overlap (1-480:1-499)

               10        20        30        40        50          
pF1KB4 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPL--
       :::.:.: .     : :.              : ::::::.:::..:.:::::..::.  
NP_001 MASNSLFSTVTPCQQNFFW-------------DPSTSRRFSPPSSSLQPGKMSDVSPVVA
               10                     20        30        40       

                                        60        70          80   
pF1KB4 ---------------------------------GAPDAGAALAGKLRS--GDRSMVEVLA
                                        .:  :.:: . .::    .:.:::..:
NP_001 AQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIA
        50        60        70        80        90       100       

            90       100       110       120       130       140   
pF1KB4 DHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAE
       :::.::::::::::::::::.:::::::::.::::::::.:::::.::::::::::::::
NP_001 DHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAE
       110       120       130       140       150       160       

           150       160       170       180       190       200   
pF1KB4 LRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREP
       ::::.:.::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_001 LRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREP
       170       180       190       200       210       220       

           210       220       230       240       250        260  
pF1KB4 RRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHS-TAFNPQ
       ::::::::: .:: :: ::.:::.: .. . .:::.    .:  ::: ::: . . ::::
NP_001 RRHRQKLDD-SKP-SL-FSDRLSDLGRIPHPSMRVG----VPPQNPRPSLNSAPSPFNPQ
       230         240        250       260           270       280

            270       280        290       300       310       320 
pF1KB4 PQSQMQDTRQIQPSPPWSYDQSY-QYLGSIASPSVHPATPISPGRASGMTTLSAELSSRL
        :::. : :: : :::::::::: .::....:::.: .::.:  :..:. ... ..  :.
NP_001 GQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAIT-DVPRRI
              290       300       310       320       330          

             330       340            350       360       370      
pF1KB4 STAPDLTAFSDPRQFPALPSI-----SDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATR
       : : .:  ::::::::.. :.     :.::::::..:::.: :::::...::::   .:.
NP_001 SGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTP-PVTSGMSLGMSA---TTH
     340       350       360       370       380        390        

        380       390       400       410        420       430     
pF1KB4 YHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMV-GGERSPPRILPPCTNA
       ::::::::::::::.:.::::.::  : ::::.:.::::: :: ::.::: :.:::::..
NP_001 YHTYLPPPYPGSSQSQSGPFQTSSTPY-LYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTT
         400       410       420        430       440       450    

         440       450       460       470       480
pF1KB4 STGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
       :.::.::::.::::.: :.:.::::.::: .  :.:..:.:::::
NP_001 SNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
          460       470       480       490         

>>XP_011513264 (OMIM: 119600,156510,600211) PREDICTED: r  (567 aa)
 initn: 1554 init1: 880 opt: 1913  Z-score: 1224.4  bits: 236.2 E(85289): 1.8e-61
Smith-Waterman score: 1965; 60.4% identity (77.5% similar) in 525 aa overlap (1-480:69-567)

                                             10        20        30
pF1KB4                               MASDSIFESFPSYPQCFMRECILGMNPSRD
                                     :::.:.: .     : :.            
XP_011 QPPRPTESFKAASSIYNRGYKFYLKKKGGTMASNSLFSTVTPCQQNFFW-----------
       40        50        60        70        80                  

               40        50                                        
pF1KB4 VHDASTSRRFTPPSTALSPGKMSEASPL--------------------------------
         : ::::::.:::..:.:::::..::.                                
XP_011 --DPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAA
          90       100       110       120       130       140     

          60        70          80        90       100       110   
pF1KB4 ---GAPDAGAALAGKLRS--GDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLP
          .:  :.:: . .::    .:.:::..::::.::::::::::::::::.:::::::::
XP_011 AAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLP
         150       160       170       180       190       200     

           120       130       140       150       160       170   
pF1KB4 IAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSF
       .::::::::.:::::.::::::::::::::::::.:.:::::::::::::::::::::::
XP_011 VAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSF
         210       220       230       240       250       260     

           180       190       200       210       220       230   
pF1KB4 TLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRR
       :::::::::::::::::::::.::::::::::::::::: .:: :: ::.:::.: .. .
XP_011 TLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDD-SKP-SL-FSDRLSDLGRIPH
         270       280       290       300          310       320  

           240       250        260       270       280        290 
pF1KB4 TAMRVSPHHPAPTPNPRASLNHS-TAFNPQPQSQMQDTRQIQPSPPWSYDQSY-QYLGSI
        .:::.    .:  ::: ::: . . :::: :::. : :: : :::::::::: .::...
XP_011 PSMRVG----VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQM
                330       340       350       360       370        

             300       310       320       330       340           
pF1KB4 ASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSI-----SDPR
       .:::.: .::.:  :..:. ... ..  :.: : .:  ::::::::.. :.     :.::
XP_011 TSPSIHSTTPLSSTRGTGLPAIT-DVPRRISGASELGPFSDPRQFPSISSLTESRFSNPR
      380       390       400        410       420       430       

        350       360       370       380       390       400      
pF1KB4 MHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLY
       ::::..:::.: :::::...::::   .:.::::::::::::::.:.::::.::  : ::
XP_011 MHYPATFTYTP-PVTSGMSLGMSA---TTHYHTYLPPPYPGSSQSQSGPFQTSSTPY-LY
       440        450       460          470       480       490   

        410        420       430       440       450       460     
pF1KB4 YGASAGSYQFSMV-GGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTN
       ::.:.::::: :: ::.::: :.:::::..:.::.::::.::::.: :.:.::::.::: 
XP_011 YGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTV
            500       510       520       530       540       550  

         470       480
pF1KB4 MAPSARLEEAVWRPY
       .  :.:..:.:::::
XP_011 LNSSGRMDESVWRPY
            560       

>>XP_011528072 (OMIM: 151385,601399) PREDICTED: runt-rel  (277 aa)
 initn: 1801 init1: 1801 opt: 1810  Z-score: 1163.9  bits: 224.0 E(85289): 4.3e-58
Smith-Waterman score: 1810; 96.4% identity (97.5% similar) in 279 aa overlap (1-279:1-275)

               10        20        30        40        50        60
pF1KB4 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEASPLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 MASDSIFESFPSYPQCFMRECILGMNPSRDVHDASTSRRFTPPSTALSPGKMSEALPLGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 HHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPAT
       ::::::::::::::::::::::::::::.    . . ::                     
XP_011 HHPAPTPNPRASLNHSTAFNPQPQSQMQE----EDTAPWRC                   
              250       260           270                          

              310       320       330       340       350       360
pF1KB4 PISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPV




480 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 21:46:48 2016 done: Thu Nov  3 21:46:49 2016
 Total Scan time:  8.450 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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