FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4862, 485 aa 1>>>pF1KB4862 485 - 485 aa - 485 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6835+/-0.000363; mu= 16.4327+/- 0.023 mean_var=81.7577+/-16.744, 0's: 0 Z-trim(115.0): 156 B-trim: 484 in 2/53 Lambda= 0.141844 statistics sampled from 25058 (25220) to 25058 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.296), width: 16 Scan time: 8.610 The best scores are: opt bits E(85289) XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 3384 702.4 7.4e-202 NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 3384 702.4 7.4e-202 XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 3142 652.8 5.6e-187 XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 2870 597.1 3e-170 XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 2870 597.2 3.3e-170 XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 2870 597.2 3.6e-170 NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 2861 595.3 1.1e-169 XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 2022 423.6 5e-118 XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 1513 319.5 1.3e-86 NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 1513 319.5 1.3e-86 XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 1513 319.5 1.3e-86 NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 1513 319.6 1.6e-86 XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 1508 318.4 2.5e-86 NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 1499 316.5 7.5e-86 NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 1373 290.6 3e-78 NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 465 104.9 2.9e-22 NP_002031 (OMIM: 600609) GA-binding protein alpha ( 454) 468 105.6 3e-22 XP_011527823 (OMIM: 600609) PREDICTED: GA-binding ( 454) 468 105.6 3e-22 XP_005260995 (OMIM: 600609) PREDICTED: GA-binding ( 454) 468 105.6 3e-22 NP_001184226 (OMIM: 600609) GA-binding protein alp ( 454) 468 105.6 3e-22 XP_011527822 (OMIM: 600609) PREDICTED: GA-binding ( 454) 468 105.6 3e-22 XP_016883802 (OMIM: 600609) PREDICTED: GA-binding ( 454) 468 105.6 3e-22 NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 465 105.0 4e-22 XP_011541003 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 465 105.0 4.3e-22 XP_016872895 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 465 105.0 4.3e-22 NP_001161153 (OMIM: 193067) Friend leukemia integr ( 419) 465 105.0 4.3e-22 XP_016872894 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 465 105.0 4.3e-22 NP_002008 (OMIM: 193067) Friend leukemia integrati ( 452) 465 105.0 4.6e-22 XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 448 101.5 4.9e-21 XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 448 101.5 4.9e-21 NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 445 100.9 6.5e-21 NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 445 100.9 6.9e-21 NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 445 100.9 7.8e-21 XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 445 100.9 7.9e-21 NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 445 100.9 7.9e-21 NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 445 100.9 8.2e-21 NP_001129626 (OMIM: 165080) transcriptional regula ( 486) 445 100.9 8.2e-21 NP_001230357 (OMIM: 165080) transcriptional regula ( 486) 445 100.9 8.2e-21 NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 438 99.3 1.3e-20 NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 430 97.8 5.6e-20 NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 430 97.8 6.1e-20 NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 430 97.8 6.4e-20 NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 430 97.9 6.6e-20 NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 430 97.9 6.6e-20 NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 430 97.9 6.6e-20 XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 430 97.9 6.8e-20 XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 430 97.9 6.8e-20 XP_011513470 (OMIM: 600541) PREDICTED: ETS translo ( 477) 430 97.9 6.8e-20 XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 430 97.9 6.8e-20 NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 430 97.9 6.8e-20 >>XP_016872803 (OMIM: 164720) PREDICTED: protein C-ets-1 (485 aa) initn: 3384 init1: 3384 opt: 3384 Z-score: 3745.0 bits: 702.4 E(85289): 7.4e-202 Smith-Waterman score: 3384; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485) 10 20 30 40 50 60 pF1KB4 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 VKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 KRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK 430 440 450 460 470 480 pF1KB4 PDADE ::::: XP_016 PDADE >>NP_001137292 (OMIM: 164720) protein C-ets-1 isoform 1 (485 aa) initn: 3384 init1: 3384 opt: 3384 Z-score: 3745.0 bits: 702.4 E(85289): 7.4e-202 Smith-Waterman score: 3384; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485) 10 20 30 40 50 60 pF1KB4 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 VKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 KRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK 430 440 450 460 470 480 pF1KB4 PDADE ::::: NP_001 PDADE >>XP_016872804 (OMIM: 164720) PREDICTED: protein C-ets-1 (450 aa) initn: 3142 init1: 3142 opt: 3142 Z-score: 3477.8 bits: 652.8 E(85289): 5.6e-187 Smith-Waterman score: 3142; 100.0% identity (100.0% similar) in 450 aa overlap (36-485:1-450) 10 20 30 40 50 60 pF1KB4 DSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQEVPTG :::::::::::::::::::::::::::::: XP_016 MNCGFQSNYHQQRPCYPFWDEMATQEVPTG 10 20 30 70 80 90 100 110 120 pF1KB4 LEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWV 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 MWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKPYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKPYQ 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 VNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKY 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 ENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIESYDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIESYDSC 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 DRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNKDKPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNKDKPVI 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 PAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNK 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB4 PKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE 400 410 420 430 440 450 >>XP_016872805 (OMIM: 164720) PREDICTED: protein C-ets-1 (418 aa) initn: 2870 init1: 2870 opt: 2870 Z-score: 3177.5 bits: 597.1 E(85289): 3e-170 Smith-Waterman score: 2870; 99.5% identity (99.5% similar) in 417 aa overlap (69-485:2-418) 40 50 60 70 80 90 pF1KB4 GFQSNYHQQRPCYPFWDEMATQEVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFS : ::::::::::::::::::::::::::: XP_016 MCEPDMECADVPLLTPSSKEMMSQALKATFS 10 20 30 100 110 120 130 140 150 pF1KB4 GFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFL 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 ELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSE 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 FSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPD 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 NMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAA 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB4 LPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFI 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB4 SWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF 340 350 360 370 380 390 460 470 480 pF1KB4 VCDLQSLLGYTPEELHAMLDVKPDADE ::::::::::::::::::::::::::: XP_016 VCDLQSLLGYTPEELHAMLDVKPDADE 400 410 >>XP_011540952 (OMIM: 164720) PREDICTED: protein C-ets-1 (475 aa) initn: 2870 init1: 2870 opt: 2870 Z-score: 3176.7 bits: 597.2 E(85289): 3.3e-170 Smith-Waterman score: 2870; 99.5% identity (99.5% similar) in 417 aa overlap (69-485:59-475) 40 50 60 70 80 90 pF1KB4 GFQSNYHQQRPCYPFWDEMATQEVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFS : ::::::::::::::::::::::::::: XP_011 LNSGAAELQLLSFVFPASLPCNGQGLIGTMCEPDMECADVPLLTPSSKEMMSQALKATFS 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB4 GFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFL 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB4 ELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSE 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB4 FSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPD 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB4 NMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAA 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB4 LPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFI 330 340 350 360 370 380 400 410 420 430 440 450 pF1KB4 SWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF 390 400 410 420 430 440 460 470 480 pF1KB4 VCDLQSLLGYTPEELHAMLDVKPDADE ::::::::::::::::::::::::::: XP_011 VCDLQSLLGYTPEELHAMLDVKPDADE 450 460 470 >>XP_011540951 (OMIM: 164720) PREDICTED: protein C-ets-1 (519 aa) initn: 2870 init1: 2870 opt: 2870 Z-score: 3176.1 bits: 597.2 E(85289): 3.6e-170 Smith-Waterman score: 3294; 93.4% identity (93.4% similar) in 517 aa overlap (3-485:3-519) 10 20 30 40 50 60 pF1KB4 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ 10 20 30 40 50 60 70 80 pF1KB4 EVPTGLEHCVS----------------------------------DMECADVPLLTPSSK ::::::::::: ::::::::::::::: XP_011 EVPTGLEHCVSGLNSGAAELQLLSFVFPASLPCNGQGLIGTMCEPDMECADVPLLTPSSK 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB4 EMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNG 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB4 AALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISY 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB4 GIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQND 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB4 YFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPS 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB4 YDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB4 ELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNII 430 440 450 460 470 480 450 460 470 480 pF1KB4 HKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE ::::::::::::::::::::::::::::::::::::::: XP_011 HKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE 490 500 510 >>NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 [Ho (441 aa) initn: 2861 init1: 2861 opt: 2861 Z-score: 3167.2 bits: 595.3 E(85289): 1.1e-169 Smith-Waterman score: 2861; 100.0% identity (100.0% similar) in 414 aa overlap (72-485:28-441) 50 60 70 80 90 100 pF1KB4 SNYHQQRPCYPFWDEMATQEVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFT :::::::::::::::::::::::::::::: NP_005 MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFT 10 20 30 40 50 110 120 130 140 150 160 pF1KB4 KEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELA 60 70 80 90 100 110 170 180 190 200 210 220 pF1KB4 PDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSE 120 130 140 150 160 170 230 240 250 260 270 280 pF1KB4 PSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMC 180 190 200 210 220 230 290 300 310 320 330 340 pF1KB4 MGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPN 240 250 260 270 280 290 350 360 370 380 390 400 pF1KB4 HKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWT 300 310 320 330 340 350 410 420 430 440 450 460 pF1KB4 GDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCD 360 370 380 390 400 410 470 480 pF1KB4 LQSLLGYTPEELHAMLDVKPDADE :::::::::::::::::::::::: NP_005 LQSLLGYTPEELHAMLDVKPDADE 420 430 440 >>XP_016872806 (OMIM: 164720) PREDICTED: protein C-ets-1 (398 aa) initn: 2021 init1: 2021 opt: 2022 Z-score: 2239.9 bits: 423.6 E(85289): 5e-118 Smith-Waterman score: 2609; 82.1% identity (82.1% similar) in 485 aa overlap (1-485:1-398) 10 20 30 40 50 60 pF1KB4 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 VKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIE :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRG------------ 250 260 270 280 310 320 330 340 350 360 pF1KB4 SYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNK XP_016 ------------------------------------------------------------ 370 380 390 400 410 420 pF1KB4 DKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWG ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ---------------SGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWG 290 300 310 320 330 430 440 450 460 470 480 pF1KB4 KRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK 340 350 360 370 380 390 pF1KB4 PDADE ::::: XP_016 PDADE >>XP_005260992 (OMIM: 164740) PREDICTED: protein C-ets-2 (469 aa) initn: 1464 init1: 877 opt: 1513 Z-score: 1676.0 bits: 319.5 E(85289): 1.3e-86 Smith-Waterman score: 1519; 54.7% identity (76.5% similar) in 439 aa overlap (55-485:45-469) 30 40 50 60 70 80 pF1KB4 QGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQEVPTGLEHCVSDMECADVPLLTPS .:.. :::::::. : ..::::: XP_005 VANSYRGTLKRQPAFDTFDGSLFAVFPSLNEEQTLQEVPTGLDSISHDSANCELPLLTPC 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 SKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCM :: .:::::::::::: :::.::::::.: :.: .: .:..::.::::: .:..:.: : XP_005 SKAVMSQALKATFSGFKKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLQRFGM 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB4 NGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKP----YQVNGVNPAYPESRYTS :: :: :::. :::::::::::::::::: . ::. . :. :. . :. . . XP_005 NGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQEKTEDQYEENSHLTSVPH--WIN 140 150 160 170 180 190 210 220 230 240 250 pF1KB4 DYFISYGIEHAQCVPPSEFSEPSFITESY-QTLHPISSEELLSLKYEND-YPSVILRDPL . ...: :.: : .. .. . ... : :. .:: . : . .:. : XP_005 SNTLGFGTEQA----PYGMQTQNYPKGGLLDSMCPASTPSVLSSEQEFQMFPKSRL---- 200 210 220 230 240 260 270 280 290 300 310 pF1KB4 QTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFES-IESYDSCDRLTQSWSSQSS .... : ...:. .:. . .. : .:: :. .:..: : : :::.:::: XP_005 --SSVSVTYCSVSQDF-PGSNLNLLTNNSGTPKDHDSPENGADSFESSDSLLQSWNSQSS 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 FNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRAD-LNKDKPVIPAAALAGYTGS . ..:::::..::. .: .: .:: .::::...:.: ... :::::::.:::.::: XP_005 LLDVQRVPSFESFE-DDCSQSLCLNKPTMSFKDYIQERSDPVEQGKPVIPAAVLAGFTGS 310 320 330 340 350 360 380 390 400 410 420 430 pF1KB4 GPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRG :::::::::::::.:::::::::::::::::::.:::::::::::::::::::::::::: XP_005 GPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRG 370 380 390 400 410 420 440 450 460 470 480 pF1KB4 LRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE :::::::::::::.:::::::::::::.:::.:::::::.: :.::... XP_005 LRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED 430 440 450 460 >>NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 [Ho (469 aa) initn: 1464 init1: 877 opt: 1513 Z-score: 1676.0 bits: 319.5 E(85289): 1.3e-86 Smith-Waterman score: 1519; 54.7% identity (76.5% similar) in 439 aa overlap (55-485:45-469) 30 40 50 60 70 80 pF1KB4 QGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQEVPTGLEHCVSDMECADVPLLTPS .:.. :::::::. : ..::::: NP_005 VANSYRGTLKRQPAFDTFDGSLFAVFPSLNEEQTLQEVPTGLDSISHDSANCELPLLTPC 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 SKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCM :: .:::::::::::: :::.::::::.: :.: .: .:..::.::::: .:..:.: : NP_005 SKAVMSQALKATFSGFKKEQRRLGIPKNPWLWSEQQVCQWLLWATNEFSLVNVNLQRFGM 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB4 NGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKP----YQVNGVNPAYPESRYTS :: :: :::. :::::::::::::::::: . ::. . :. :. . :. . . NP_005 NGQMLCNLGKERFLELAPDFVGDILWEHLEQMIKENQEKTEDQYEENSHLTSVPH--WIN 140 150 160 170 180 190 210 220 230 240 250 pF1KB4 DYFISYGIEHAQCVPPSEFSEPSFITESY-QTLHPISSEELLSLKYEND-YPSVILRDPL . ...: :.: : .. .. . ... : :. .:: . : . .:. : NP_005 SNTLGFGTEQA----PYGMQTQNYPKGGLLDSMCPASTPSVLSSEQEFQMFPKSRL---- 200 210 220 230 240 260 270 280 290 300 310 pF1KB4 QTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFES-IESYDSCDRLTQSWSSQSS .... : ...:. .:. . .. : .:: :. .:..: : : :::.:::: NP_005 --SSVSVTYCSVSQDF-PGSNLNLLTNNSGTPKDHDSPENGADSFESSDSLLQSWNSQSS 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 FNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRAD-LNKDKPVIPAAALAGYTGS . ..:::::..::. .: .: .:: .::::...:.: ... :::::::.:::.::: NP_005 LLDVQRVPSFESFE-DDCSQSLCLNKPTMSFKDYIQERSDPVEQGKPVIPAAVLAGFTGS 310 320 330 340 350 360 380 390 400 410 420 430 pF1KB4 GPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRG :::::::::::::.:::::::::::::::::::.:::::::::::::::::::::::::: NP_005 GPIQLWQFLLELLSDKSCQSFISWTGDGWEFKLADPDEVARRWGKRKNKPKMNYEKLSRG 370 380 390 400 410 420 440 450 460 470 480 pF1KB4 LRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE :::::::::::::.:::::::::::::.:::.:::::::.: :.::... NP_005 LRYYYDKNIIHKTSGKRYVYRFVCDLQNLLGFTPEELHAILGVQPDTED 430 440 450 460 485 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:16:04 2016 done: Fri Nov 4 03:16:06 2016 Total Scan time: 8.610 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]