Result of FASTA (omim) for
pF1KB4877
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4877, 806 aa
1>>>pF1KB4877 806 - 806 aa - 806 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4678+/-0.000419; mu= 3.2095+/- 0.026
mean_var=273.0056+/-56.687, 0's: 0 Z-trim(121.2): 85 B-trim: 2666 in 2/53
Lambda= 0.077623
statistics sampled from 37314 (37413) to 37314 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.439), width: 16
Scan time: 14.580
The best scores are: opt bits E(85289)
NP_004492 (OMIM: 602869) heterogeneous nuclear rib ( 806) 5525 632.6 2.1e-180
XP_016856606 (OMIM: 602869) PREDICTED: heterogeneo ( 806) 5525 632.6 2.1e-180
XP_016856605 (OMIM: 602869) PREDICTED: heterogeneo ( 825) 4236 488.3 5.9e-137
XP_016856604 (OMIM: 602869) PREDICTED: heterogeneo ( 825) 4236 488.3 5.9e-137
NP_114032 (OMIM: 602869) heterogeneous nuclear rib ( 825) 4236 488.3 5.9e-137
XP_011524694 (OMIM: 605800) PREDICTED: heterogeneo ( 792) 1966 234.0 1.9e-60
NP_008971 (OMIM: 605800) heterogeneous nuclear rib ( 856) 1966 234.1 2e-60
XP_005258516 (OMIM: 605800) PREDICTED: heterogeneo ( 866) 1966 234.1 2.1e-60
NP_001308140 (OMIM: 605800) heterogeneous nuclear ( 756) 1944 231.6 1e-59
NP_653333 (OMIM: 605800) heterogeneous nuclear rib ( 756) 1944 231.6 1e-59
NP_001308137 (OMIM: 605800) heterogeneous nuclear ( 756) 1944 231.6 1e-59
XP_005258521 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 1944 231.6 1e-59
XP_005258520 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 1944 231.6 1e-59
XP_011524695 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 1944 231.6 1e-59
XP_005258522 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 1944 231.6 1e-59
XP_011524697 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 1944 231.6 1e-59
XP_011524696 (OMIM: 605800) PREDICTED: heterogeneo ( 766) 1944 231.6 1e-59
NP_001287945 (OMIM: 605800) heterogeneous nuclear ( 767) 1944 231.6 1e-59
XP_005258518 (OMIM: 605800) PREDICTED: heterogeneo ( 777) 1944 231.6 1e-59
NP_004930 (OMIM: 601257) ATP-dependent RNA helicas ( 740) 280 45.2 0.0013
NP_001317177 (OMIM: 605372) heterogeneous nuclear ( 356) 261 42.8 0.0032
NP_001317176 (OMIM: 605372) heterogeneous nuclear ( 356) 261 42.8 0.0032
NP_919223 (OMIM: 605372) heterogeneous nuclear rib ( 378) 261 42.8 0.0034
NP_001317178 (OMIM: 605372) heterogeneous nuclear ( 378) 261 42.8 0.0034
>>NP_004492 (OMIM: 602869) heterogeneous nuclear ribonuc (806 aa)
initn: 5525 init1: 5525 opt: 5525 Z-score: 3360.0 bits: 632.6 E(85289): 2.1e-180
Smith-Waterman score: 5525; 100.0% identity (100.0% similar) in 806 aa overlap (1-806:1-806)
10 20 30 40 50 60
pF1KB4 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 AGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 PQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 KAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 GGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS
730 740 750 760 770 780
790 800
pF1KB4 QGYNQWQQGQFWGQKPWSQHYHQGYY
::::::::::::::::::::::::::
NP_004 QGYNQWQQGQFWGQKPWSQHYHQGYY
790 800
>>XP_016856606 (OMIM: 602869) PREDICTED: heterogeneous n (806 aa)
initn: 5525 init1: 5525 opt: 5525 Z-score: 3360.0 bits: 632.6 E(85289): 2.1e-180
Smith-Waterman score: 5525; 100.0% identity (100.0% similar) in 806 aa overlap (1-806:1-806)
10 20 30 40 50 60
pF1KB4 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELSYAKNGQDLGVAFKISKEVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 AGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 PQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 KAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 GGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQS
730 740 750 760 770 780
790 800
pF1KB4 QGYNQWQQGQFWGQKPWSQHYHQGYY
::::::::::::::::::::::::::
XP_016 QGYNQWQQGQFWGQKPWSQHYHQGYY
790 800
>>XP_016856605 (OMIM: 602869) PREDICTED: heterogeneous n (825 aa)
initn: 4147 init1: 4147 opt: 4236 Z-score: 2579.7 bits: 488.3 E(85289): 5.9e-137
Smith-Waterman score: 5477; 97.7% identity (97.7% similar) in 825 aa overlap (1-806:1-825)
10 20 30 40 50 60
pF1KB4 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
130 140 150 160 170 180
190 200 210 220
pF1KB4 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKGG
:::::::::::::::::::::::::::::::: :::::::::
XP_016 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB4 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB4 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB4 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB4 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB4 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB4 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB4 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
730 740 750 760 770 780
770 780 790 800
pF1KB4 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
790 800 810 820
>>XP_016856604 (OMIM: 602869) PREDICTED: heterogeneous n (825 aa)
initn: 4147 init1: 4147 opt: 4236 Z-score: 2579.7 bits: 488.3 E(85289): 5.9e-137
Smith-Waterman score: 5477; 97.7% identity (97.7% similar) in 825 aa overlap (1-806:1-825)
10 20 30 40 50 60
pF1KB4 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
130 140 150 160 170 180
190 200 210 220
pF1KB4 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKGG
:::::::::::::::::::::::::::::::: :::::::::
XP_016 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB4 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB4 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB4 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB4 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB4 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB4 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB4 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
730 740 750 760 770 780
770 780 790 800
pF1KB4 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
790 800 810 820
>>NP_114032 (OMIM: 602869) heterogeneous nuclear ribonuc (825 aa)
initn: 4147 init1: 4147 opt: 4236 Z-score: 2579.7 bits: 488.3 E(85289): 5.9e-137
Smith-Waterman score: 5477; 97.7% identity (97.7% similar) in 825 aa overlap (1-806:1-825)
10 20 30 40 50 60
pF1KB4 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
130 140 150 160 170 180
190 200 210 220
pF1KB4 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGG-------------------DGKTEQKGG
:::::::::::::::::::::::::::::::: :::::::::
NP_114 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGAPAAGDGKTEQKGG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB4 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB4 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 ISRDRLSASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVR
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB4 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 IGWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFESDEVELS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB4 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 YAKNGQDLGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB4 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNILGTNTIMDKMMVA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB4 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 GFKKQMADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB4 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 RKAVVVCPKDEDYKQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKE
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 EAQKLLEQYKEESKKALPPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNFR
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 GGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG
730 740 750 760 770 780
770 780 790 800
pF1KB4 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
:::::::::::::::::::::::::::::::::::::::::::::
NP_114 NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
790 800 810 820
>>XP_011524694 (OMIM: 605800) PREDICTED: heterogeneous n (792 aa)
initn: 1505 init1: 715 opt: 1966 Z-score: 1206.1 bits: 234.0 E(85289): 1.9e-60
Smith-Waterman score: 2136; 47.2% identity (70.0% similar) in 781 aa overlap (6-779:1-695)
10 20 30 40 50 60
pF1KB4 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
..:..:::.::.:::..: :. .:::::: :::::::. :: : : :
XP_011 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEE----PDDER---EL
10 20 30 40
70 80 90 100 110 120
pF1KB4 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
: . : :: : :. . ::.: : . :.. .: .: .: .:
XP_011 D-ADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPH-------AEPGGYSG--PDGH
50 60 70 80 90
130 140 150 160 170 180
pF1KB4 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
. .. . ... : : ... :.: : :.. : ..:: : :
XP_011 YAMDNITRQNQFYDTQVIKQ-ENESGYERR---------------PLEMEQQ-QAYRPEM
100 110 120 130 140
190 200 210 220 230 240
pF1KB4 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE
: :...:::.. :: : : . . .:. ..:: . :..::::::
XP_011 KTEM-KQGAPTSFL-----PPEASQLKPD-------RQQFQSRKRPYE---ENRGRGYFE
150 160 170 180
250 260 270 280 290 300
pF1KB4 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL
. :. :..:::::.::... ::::.: .::::::::::..::: :. ::.:.::.:
XP_011 HRED---RRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYL
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB4 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
:.:.:::::: .:.::::::..:.: :.:: . . : : ::::::: . . :::: :::
XP_011 WSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSY
250 260 270 280 290 300
370 380 390 400 410
pF1KB4 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKNGQDLGVAFKISKEV
::. : :. : . :.::.:: ::::: :::.:: ...::::..:::. .:.::.:.::.
XP_011 GYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEA
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB4 LAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCE
:.:. :.:::: .::::::::::. .:: . .::::..:: .:.:: ::. : .::
XP_011 LGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECE
370 380 390 400 410 420
480 490 500 510 520 530
pF1KB4 VVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQ
..::.:::.::::::. :::: ::.: :::::::.::::: : :...: .:. ..:.:
XP_011 ILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQ
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB4 RAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRT
.: :::...:.::::::::.::::::: ..:::::: : ::::::.:.:: ::: :.::
XP_011 QATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRT
490 500 510 520 530 540
600 610 620 630 640 650
pF1KB4 QKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKAL
:... ::::.:.::::.::.:::::.:.. .::. ..:::.:::.::..::.::..::
XP_011 IKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAG
550 560 570 580 590 600
660 670 680 690 700 710
pF1KB4 PPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-----RGGAPGNRGGYNR
:: .: . .:.. ::: ::::: ::.: :: :::::..
XP_011 PPPEK-----RFDNRG---------GGGFRGRGG----GGGFQRYENRGPPGGNRGGFQ-
610 620 630 640
720 730 740 750 760 770
pF1KB4 RGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNN
.::::.::.:. . :. : :.::. :: : :: : :.: :: . :
XP_011 -----NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGNNNRDNNNSNNRG-SYN
650 660 670 680
780 790 800
pF1KB4 RGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
:. ..:
XP_011 RAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSS
690 700 710 720 730 740
>>NP_008971 (OMIM: 605800) heterogeneous nuclear ribonuc (856 aa)
initn: 1505 init1: 715 opt: 1966 Z-score: 1205.7 bits: 234.1 E(85289): 2e-60
Smith-Waterman score: 2136; 47.2% identity (70.0% similar) in 781 aa overlap (6-779:1-695)
10 20 30 40 50 60
pF1KB4 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
..:..:::.::.:::..: :. .:::::: :::::::. :: : : :
NP_008 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEE----PDDER---EL
10 20 30 40
70 80 90 100 110 120
pF1KB4 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
: . : :: : :. . ::.: : . :.. .: .: .: .:
NP_008 D-ADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPH-------AEPGGYSG--PDGH
50 60 70 80 90
130 140 150 160 170 180
pF1KB4 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
. .. . ... : : ... :.: : :.. : ..:: : :
NP_008 YAMDNITRQNQFYDTQVIKQ-ENESGYERR---------------PLEMEQQ-QAYRPEM
100 110 120 130 140
190 200 210 220 230 240
pF1KB4 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE
: :...:::.. :: : : . . .:. ..:: . :..::::::
NP_008 KTEM-KQGAPTSFL-----PPEASQLKPD-------RQQFQSRKRPYE---ENRGRGYFE
150 160 170 180
250 260 270 280 290 300
pF1KB4 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL
. :. :..:::::.::... ::::.: .::::::::::..::: :. ::.:.::.:
NP_008 HRED---RRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYL
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB4 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
:.:.:::::: .:.::::::..:.: :.:: . . : : ::::::: . . :::: :::
NP_008 WSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSY
250 260 270 280 290 300
370 380 390 400 410
pF1KB4 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKNGQDLGVAFKISKEV
::. : :. : . :.::.:: ::::: :::.:: ...::::..:::. .:.::.:.::.
NP_008 GYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEA
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB4 LAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCE
:.:. :.:::: .::::::::::. .:: . .::::..:: .:.:: ::. : .::
NP_008 LGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECE
370 380 390 400 410 420
480 490 500 510 520 530
pF1KB4 VVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQ
..::.:::.::::::. :::: ::.: :::::::.::::: : :...: .:. ..:.:
NP_008 ILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQ
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB4 RAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRT
.: :::...:.::::::::.::::::: ..:::::: : ::::::.:.:: ::: :.::
NP_008 QATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRT
490 500 510 520 530 540
600 610 620 630 640 650
pF1KB4 QKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKAL
:... ::::.:.::::.::.:::::.:.. .::. ..:::.:::.::..::.::..::
NP_008 IKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAG
550 560 570 580 590 600
660 670 680 690 700 710
pF1KB4 PPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-----RGGAPGNRGGYNR
:: .: . .:.. ::: ::::: ::.: :: :::::..
NP_008 PPPEK-----RFDNRG---------GGGFRGRGG----GGGFQRYENRGPPGGNRGGFQ-
610 620 630 640
720 730 740 750 760 770
pF1KB4 RGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNN
.::::.::.:. . :. : :.::. :: : :: : :.: :: . :
NP_008 -----NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGNNNRDNNNSNNRG-SYN
650 660 670 680
780 790 800
pF1KB4 RGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
:. ..:
NP_008 RAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSS
690 700 710 720 730 740
>>XP_005258516 (OMIM: 605800) PREDICTED: heterogeneous n (866 aa)
initn: 1505 init1: 715 opt: 1966 Z-score: 1205.6 bits: 234.1 E(85289): 2.1e-60
Smith-Waterman score: 2136; 47.2% identity (70.0% similar) in 781 aa overlap (6-779:1-695)
10 20 30 40 50 60
pF1KB4 MSSSPVNVKKLKVSELKEELKKRRLSDKGLKAELMERLQAALDDEEAGGRPAMEPGNGSL
..:..:::.::.:::..: :. .:::::: :::::::. :: : : :
XP_005 MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEE----PDDER---EL
10 20 30 40
70 80 90 100 110 120
pF1KB4 DLGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGP
: . : :: : :. . ::.: : . :.. .: .: .: .:
XP_005 D-ADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPH-------AEPGGYSG--PDGH
50 60 70 80 90
130 140 150 160 170 180
pF1KB4 MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAA
. .. . ... : : ... :.: : :.. : ..:: : :
XP_005 YAMDNITRQNQFYDTQVIKQ-ENESGYERR---------------PLEMEQQ-QAYRPEM
100 110 120 130 140
190 200 210 220 230 240
pF1KB4 KEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFE
: :...:::.. :: : : . . .:. ..:: . :..::::::
XP_005 KTEM-KQGAPTSFL-----PPEASQLKPD-------RQQFQSRKRPYE---ENRGRGYFE
150 160 170 180
250 260 270 280 290 300
pF1KB4 YIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFL
. :. :..:::::.::... ::::.: .::::::::::..::: :. ::.:.::.:
XP_005 HRED---RRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYL
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB4 WAGGRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSY
:.:.:::::: .:.::::::..:.: :.:: . . : : ::::::: . . :::: :::
XP_005 WSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSY
250 260 270 280 290 300
370 380 390 400 410
pF1KB4 GYSLKGIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKNGQDLGVAFKISKEV
::. : :. : . :.::.:: ::::: :::.:: ...::::..:::. .:.::.:.::.
XP_005 GYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEA
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB4 LAGRPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCE
:.:. :.:::: .::::::::::. .:: . .::::..:: .:.:: ::. : .::
XP_005 LGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECE
370 380 390 400 410 420
480 490 500 510 520 530
pF1KB4 VVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQ
..::.:::.::::::. :::: ::.: :::::::.::::: : :...: .:. ..:.:
XP_005 ILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQ
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB4 RAPQCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRT
.: :::...:.::::::::.::::::: ..:::::: : ::::::.:.:: ::: :.::
XP_005 QATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRT
490 500 510 520 530 540
600 610 620 630 640 650
pF1KB4 QKKAEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKAL
:... ::::.:.::::.::.:::::.:.. .::. ..:::.:::.::..::.::..::
XP_005 IKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAG
550 560 570 580 590 600
660 670 680 690 700 710
pF1KB4 PPEKKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-----RGGAPGNRGGYNR
:: .: . .:.. ::: ::::: ::.: :: :::::..
XP_005 PPPEK-----RFDNRG---------GGGFRGRGG----GGGFQRYENRGPPGGNRGGFQ-
610 620 630 640
720 730 740 750 760 770
pF1KB4 RGNMPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNN
.::::.::.:. . :. : :.::. :: : :: : :.: :: . :
XP_005 -----NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGNNNRDNNNSNNRG-SYN
650 660 670 680
780 790 800
pF1KB4 RGYKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
:. ..:
XP_005 RAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSS
690 700 710 720 730 740
>>NP_001308140 (OMIM: 605800) heterogeneous nuclear ribo (756 aa)
initn: 1430 init1: 715 opt: 1944 Z-score: 1193.1 bits: 231.6 E(85289): 1e-59
Smith-Waterman score: 1993; 50.7% identity (74.2% similar) in 633 aa overlap (154-779:20-595)
130 140 150 160 170 180
pF1KB4 EEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEA
.:.:. :..: ...: : : :
NP_001 MDNITRQNQFYDTQVIKQENESGY-ERRP----LEMEQQQAYRPEMKTE
10 20 30 40
190 200 210 220 230 240
pF1KB4 AGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIE
:...:::.. :: : : . . .:. ..:: . :..::::::. :
NP_001 M-KQGAPTSFL-----PPEASQLKPD-------RQQFQSRKRPYE---ENRGRGYFEHRE
50 60 70 80
250 260 270 280 290 300
pF1KB4 ENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAG
. :..:::::.::... ::::.: .::::::::::..::: :. ::.:.::.::.:
NP_001 DR---RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSG
90 100 110 120 130 140
310 320 330 340 350 360
pF1KB4 GRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYS
.:::::: .:.::::::..:.: :.:: . . : : ::::::: . . :::: :::::.
NP_001 ARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYG
150 160 170 180 190 200
370 380 390 400 410 420
pF1KB4 LKGIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKNGQDLGVAFKISKEVLAG
: :. : . :.::.:: ::::: :::.:: ...::::..:::. .:.::.:.::.:.:
NP_001 GTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGG
210 220 230 240 250 260
430 440 450 460 470 480
pF1KB4 RPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVM
. :.:::: .::::::::::. .:: . .::::..:: .:.:: ::. : .::..:
NP_001 QALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILM
270 280 290 300 310 320
490 500 510 520 530 540
pF1KB4 MIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAP
:.:::.::::::. :::: ::.: :::::::.::::: : :...: .:. ..:.:.:
NP_001 MVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQAT
330 340 350 360 370 380
550 560 570 580 590 600
pF1KB4 QCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKK
:::...:.::::::::.::::::: ..:::::: : ::::::.:.:: ::: :.:: :.
NP_001 QCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKR
390 400 410 420 430 440
610 620 630 640 650 660
pF1KB4 AEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPE
.. ::::.:.::::.::.:::::.:.. .::. ..:::.:::.::..::.::..:: ::
NP_001 TDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPP
450 460 470 480 490 500
670 680 690 700 710
pF1KB4 KKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-----RGGAPGNRGGYNRRGN
.: . .:.. ::: ::::: ::.: :: :::::..
NP_001 EK-----RFDNRG---------GGGFRGRGG----GGGFQRYENRGPPGGNRGGFQ----
510 520 530 540
720 730 740 750 760 770
pF1KB4 MPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGY
.::::.::.:. . :. : :.::. :: : :: : :.: :: . ::.
NP_001 --NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGNNNRDNNNSNNRG-SYNRAP
550 560 570 580 590
780 790 800
pF1KB4 KNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
..:
NP_001 QQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSP
600 610 620 630 640 650
>>NP_653333 (OMIM: 605800) heterogeneous nuclear ribonuc (756 aa)
initn: 1430 init1: 715 opt: 1944 Z-score: 1193.1 bits: 231.6 E(85289): 1e-59
Smith-Waterman score: 1993; 50.7% identity (74.2% similar) in 633 aa overlap (154-779:20-595)
130 140 150 160 170 180
pF1KB4 EEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEA
.:.:. :..: ...: : : :
NP_653 MDNITRQNQFYDTQVIKQENESGY-ERRP----LEMEQQQAYRPEMKTE
10 20 30 40
190 200 210 220 230 240
pF1KB4 AGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGVKRPREDHGRGYFEYIE
:...:::.. :: : : . . .:. ..:: . :..::::::. :
NP_653 M-KQGAPTSFL-----PPEASQLKPD-------RQQFQSRKRPYE---ENRGRGYFEHRE
50 60 70 80
250 260 270 280 290 300
pF1KB4 ENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDRLSASSLTMESFAFLWAG
. :..:::::.::... ::::.: .::::::::::..::: :. ::.:.::.::.:
NP_653 DR---RGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSG
90 100 110 120 130 140
310 320 330 340 350 360
pF1KB4 GRASYGVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYGYS
.:::::: .:.::::::..:.: :.:: . . : : ::::::: . . :::: :::::.
NP_653 ARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYG
150 160 170 180 190 200
370 380 390 400 410 420
pF1KB4 LKGIKTCNCETEDYGEKFDENDVITCFANFE-SDEVELSYAKNGQDLGVAFKISKEVLAG
: :. : . :.::.:: ::::: :::.:: ...::::..:::. .:.::.:.::.:.:
NP_653 GTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGG
210 220 230 240 250 260
430 440 450 460 470 480
pF1KB4 RPLFPHVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEKKDCEVVM
. :.:::: .::::::::::. .:: . .::::..:: .:.:: ::. : .::..:
NP_653 QALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILM
270 280 290 300 310 320
490 500 510 520 530 540
pF1KB4 MIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAP
:.:::.::::::. :::: ::.: :::::::.::::: : :...: .:. ..:.:.:
NP_653 MVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQAT
330 340 350 360 370 380
550 560 570 580 590 600
pF1KB4 QCLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKK
:::...:.::::::::.::::::: ..:::::: : ::::::.:.:: ::: :.:: :.
NP_653 QCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKR
390 400 410 420 430 440
610 620 630 640 650 660
pF1KB4 AEVEGKDLPEHAVLKMKGNFTLPEVAECFDEITYVELQKEEAQKLLEQYKEESKKALPPE
.. ::::.:.::::.::.:::::.:.. .::. ..:::.:::.::..::.::..:: ::
NP_653 TDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPP
450 460 470 480 490 500
670 680 690 700 710
pF1KB4 KKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFNMRGGNF-----RGGAPGNRGGYNRRGN
.: . .:.. ::: ::::: ::.: :: :::::..
NP_653 EK-----RFDNRG---------GGGFRGRGG----GGGFQRYENRGPPGGNRGGFQ----
510 520 530 540
720 730 740 750 760 770
pF1KB4 MPQRGGGGGGSGGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGY
.::::.::.:. . :. : :.::. :: : :: : :.: :: . ::.
NP_653 --NRGGGSGGGGNYRGGFNRS----GGGGYSQ----NRWGNNNRDNNNSNNRG-SYNRAP
550 560 570 580 590
780 790 800
pF1KB4 KNQSQGYNQWQQGQFWGQKPWSQHYHQGYY
..:
NP_653 QQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSP
600 610 620 630 640 650
806 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:34:06 2016 done: Thu Nov 3 15:34:08 2016
Total Scan time: 14.580 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]