FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4878, 511 aa 1>>>pF1KB4878 511 - 511 aa - 511 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0976+/-0.000474; mu= 19.1811+/- 0.029 mean_var=65.7517+/-13.945, 0's: 0 Z-trim(108.4): 31 B-trim: 0 in 0/49 Lambda= 0.158169 statistics sampled from 16471 (16495) to 16471 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.543), E-opt: 0.2 (0.193), width: 16 Scan time: 8.200 The best scores are: opt bits E(85289) NP_001269154 (OMIM: 182410,607575,615688) adenosin ( 511) 3421 790.2 0 NP_001269155 (OMIM: 182410,607575,615688) adenosin ( 511) 3421 790.2 0 XP_011544435 (OMIM: 182410,607575,615688) PREDICTE ( 511) 3421 790.2 0 NP_001269157 (OMIM: 182410,607575,615688) adenosin ( 469) 3154 729.3 6.1e-210 NP_001269156 (OMIM: 182410,607575,615688) adenosin ( 469) 3154 729.3 6.1e-210 NP_001269158 (OMIM: 182410,607575,615688) adenosin ( 391) 2653 614.9 1.4e-175 NP_803124 (OMIM: 182410,607575,615688) adenosine d ( 270) 1735 405.3 1.2e-112 XP_006724143 (OMIM: 182410,607575,615688) PREDICTE ( 283) 1459 342.3 1.1e-93 NP_001308979 (OMIM: 102700,608958) adenosine deami ( 228) 181 50.6 5.7e-06 NP_000013 (OMIM: 102700,608958) adenosine deaminas ( 363) 181 50.8 8.2e-06 NP_001308980 (OMIM: 102700,608958) adenosine deami ( 339) 151 43.9 0.0009 NP_001165902 (OMIM: 102772,612874) AMP deaminase 3 ( 608) 150 43.8 0.0017 NP_001020560 (OMIM: 102772,612874) AMP deaminase 3 ( 767) 150 43.9 0.002 NP_001165901 (OMIM: 102772,612874) AMP deaminase 3 ( 767) 150 43.9 0.002 NP_001020561 (OMIM: 102772,612874) AMP deaminase 3 ( 774) 150 43.9 0.002 NP_000471 (OMIM: 102772,612874) AMP deaminase 3 is ( 776) 150 43.9 0.002 >>NP_001269154 (OMIM: 182410,607575,615688) adenosine de (511 aa) initn: 3421 init1: 3421 opt: 3421 Z-score: 4218.9 bits: 790.2 E(85289): 0 Smith-Waterman score: 3421; 100.0% identity (100.0% similar) in 511 aa overlap (1-511:1-511) 10 20 30 40 50 60 pF1KB4 MLVDGPSERPALCFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVDGPSERPALCFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 MDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 SLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 IAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGET 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSI 430 440 450 460 470 480 490 500 510 pF1KB4 KYSTLLESEKNTFMEIWKKRWDKFIADVATK ::::::::::::::::::::::::::::::: NP_001 KYSTLLESEKNTFMEIWKKRWDKFIADVATK 490 500 510 >>NP_001269155 (OMIM: 182410,607575,615688) adenosine de (511 aa) initn: 3421 init1: 3421 opt: 3421 Z-score: 4218.9 bits: 790.2 E(85289): 0 Smith-Waterman score: 3421; 100.0% identity (100.0% similar) in 511 aa overlap (1-511:1-511) 10 20 30 40 50 60 pF1KB4 MLVDGPSERPALCFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVDGPSERPALCFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 MDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 SLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 IAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGET 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSI 430 440 450 460 470 480 490 500 510 pF1KB4 KYSTLLESEKNTFMEIWKKRWDKFIADVATK ::::::::::::::::::::::::::::::: NP_001 KYSTLLESEKNTFMEIWKKRWDKFIADVATK 490 500 510 >>XP_011544435 (OMIM: 182410,607575,615688) PREDICTED: a (511 aa) initn: 3421 init1: 3421 opt: 3421 Z-score: 4218.9 bits: 790.2 E(85289): 0 Smith-Waterman score: 3421; 100.0% identity (100.0% similar) in 511 aa overlap (1-511:1-511) 10 20 30 40 50 60 pF1KB4 MLVDGPSERPALCFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLVDGPSERPALCFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 MDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 SLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 IAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGET 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSI 430 440 450 460 470 480 490 500 510 pF1KB4 KYSTLLESEKNTFMEIWKKRWDKFIADVATK ::::::::::::::::::::::::::::::: XP_011 KYSTLLESEKNTFMEIWKKRWDKFIADVATK 490 500 510 >>NP_001269157 (OMIM: 182410,607575,615688) adenosine de (469 aa) initn: 3154 init1: 3154 opt: 3154 Z-score: 3890.1 bits: 729.3 E(85289): 6.1e-210 Smith-Waterman score: 3154; 100.0% identity (100.0% similar) in 469 aa overlap (43-511:1-469) 20 30 40 50 60 70 pF1KB4 CFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMK :::::::::::::::::::::::::::::: NP_001 MMRLGGRLVLNTKEELANERLMTLKIAEMK 10 20 30 80 90 100 110 120 130 pF1KB4 EAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVTMDWLVRNVTYRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVTMDWLVRNVTYRP 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 HCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQH 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 PEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 YELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLR 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 IKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNIL 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 DALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMAT 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 GHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNT 400 410 420 430 440 450 500 510 pF1KB4 FMEIWKKRWDKFIADVATK ::::::::::::::::::: NP_001 FMEIWKKRWDKFIADVATK 460 >>NP_001269156 (OMIM: 182410,607575,615688) adenosine de (469 aa) initn: 3154 init1: 3154 opt: 3154 Z-score: 3890.1 bits: 729.3 E(85289): 6.1e-210 Smith-Waterman score: 3154; 100.0% identity (100.0% similar) in 469 aa overlap (43-511:1-469) 20 30 40 50 60 70 pF1KB4 CFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMK :::::::::::::::::::::::::::::: NP_001 MMRLGGRLVLNTKEELANERLMTLKIAEMK 10 20 30 80 90 100 110 120 130 pF1KB4 EAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVTMDWLVRNVTYRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVTMDWLVRNVTYRP 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 HCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQH 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 PEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 YELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLR 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 IKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNIL 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 DALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMAT 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 GHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNT 400 410 420 430 440 450 500 510 pF1KB4 FMEIWKKRWDKFIADVATK ::::::::::::::::::: NP_001 FMEIWKKRWDKFIADVATK 460 >>NP_001269158 (OMIM: 182410,607575,615688) adenosine de (391 aa) initn: 2653 init1: 2653 opt: 2653 Z-score: 3273.4 bits: 614.9 E(85289): 1.4e-175 Smith-Waterman score: 2653; 100.0% identity (100.0% similar) in 391 aa overlap (121-511:1-391) 100 110 120 130 140 150 pF1KB4 HLIERSQVFNILRMMPKGAALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAH :::::::::::::::::::::::::::::: NP_001 MDWLVRNVTYRPHCHICFTPRGIMQFRFAH 10 20 30 160 170 180 190 200 210 pF1KB4 PTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQHPEVIYTNQNVVWSKFETI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQHPEVIYTNQNVVWSKFETI 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB4 FFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSVKTYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSVKTYQ 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB4 EVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB4 GHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSK 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB4 HPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKG 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB4 LSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVAT 340 350 360 370 380 390 pF1KB4 K : NP_001 K >>NP_803124 (OMIM: 182410,607575,615688) adenosine deami (270 aa) initn: 1735 init1: 1735 opt: 1735 Z-score: 2143.6 bits: 405.3 E(85289): 1.2e-112 Smith-Waterman score: 1735; 100.0% identity (100.0% similar) in 260 aa overlap (252-511:11-270) 230 240 250 260 270 280 pF1KB4 PVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHP :::::::::::::::::::::::::::::: NP_803 MDSLEWNWALVYELSGEHHDEEWSVKTYQEVAQKFVETHP 10 20 30 40 290 300 310 320 330 340 pF1KB4 EFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_803 EFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEAL 50 60 70 80 90 100 350 360 370 380 390 400 pF1KB4 MIPAKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_803 MIPAKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKK 110 120 130 140 150 160 410 420 430 440 450 460 pF1KB4 DIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_803 DIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMG 170 180 190 200 210 220 470 480 490 500 510 pF1KB4 IGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK :::::::::::::::::::::::::::::::::::::::::::::::::: NP_803 IGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK 230 240 250 260 270 >>XP_006724143 (OMIM: 182410,607575,615688) PREDICTED: a (283 aa) initn: 1459 init1: 1459 opt: 1459 Z-score: 1803.0 bits: 342.3 E(85289): 1.1e-93 Smith-Waterman score: 1459; 100.0% identity (100.0% similar) in 219 aa overlap (293-511:65-283) 270 280 290 300 310 320 pF1KB4 EWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGF :::::::::::::::::::::::::::::: XP_006 WGWPSPARRVCSGVCALSVLGTVSWLLCLSHRSKDVAVIAESIRMAMGLRIKFPTVVAGF 40 50 60 70 80 90 330 340 350 360 370 380 pF1KB4 DLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRI 100 110 120 130 140 150 390 400 410 420 430 440 pF1KB4 GHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDD 160 170 180 190 200 210 450 460 470 480 490 500 pF1KB4 PAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWD 220 230 240 250 260 270 510 pF1KB4 KFIADVATK ::::::::: XP_006 KFIADVATK 280 >>NP_001308979 (OMIM: 102700,608958) adenosine deaminase (228 aa) initn: 112 init1: 92 opt: 181 Z-score: 228.2 bits: 50.6 E(85289): 5.7e-06 Smith-Waterman score: 181; 27.0% identity (56.2% similar) in 185 aa overlap (317-499:41-214) 290 300 310 320 330 340 pF1KB4 KIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT-GHSL-HDYKEALMIP :::: .::.: : : :: . .: . NP_001 WPTPKWSQSPGTRLNWSPKVVELCKKYQQQTVVA-IDLAGDETIPGSSLLPGHVQAYQEA 20 30 40 50 60 350 360 370 380 390 400 pF1KB4 AKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIP .:.:.. ::::. .. . .. .: .:.: :.:::. . :. . .... NP_001 VKSGIH--RTVHAGEVG--SAEVVKEAVD--ILKTERLGHGYHTLEDQALYNRLRQENMH 70 80 90 100 110 120 410 420 430 440 450 460 pF1KB4 IEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGG .:.:: :. . . .: : : . ...::: .: . :. :. . .: NP_001 FEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKST-LDTDYQMTKRDMGF 130 140 150 160 170 180 470 480 490 500 510 pF1KB4 MKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK . .. :.: .:. : : : :.:: .... : NP_001 TEEEF---KRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL 190 200 210 220 >>NP_000013 (OMIM: 102700,608958) adenosine deaminase is (363 aa) initn: 92 init1: 92 opt: 181 Z-score: 225.3 bits: 50.8 E(85289): 8.2e-06 Smith-Waterman score: 181; 27.0% identity (56.2% similar) in 185 aa overlap (317-499:176-349) 290 300 310 320 330 340 pF1KB4 KIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT-GHSL-HDYKEALMIP :::: .::.: : : :: . .: . NP_000 VKARSILCCMRHQPNWSPKVVELCKKYQQQTVVA-IDLAGDETIPGSSLLPGHVQAYQEA 150 160 170 180 190 200 350 360 370 380 390 400 pF1KB4 AKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIP .:.:.. ::::. .. . .. .: .:.: :.:::. . :. . .... NP_000 VKSGIH--RTVHAGEVG--SAEVVKEAVD--ILKTERLGHGYHTLEDQALYNRLRQENMH 210 220 230 240 250 410 420 430 440 450 460 pF1KB4 IEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGG .:.:: :. . . .: : : . ...::: .: . :. :. . .: NP_000 FEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKST-LDTDYQMTKRDMGF 260 270 280 290 300 310 470 480 490 500 510 pF1KB4 MKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK . .. :.: .:. : : : :.:: .... : NP_000 TEEEF---KRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL 320 330 340 350 360 511 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:16:45 2016 done: Fri Nov 4 03:16:47 2016 Total Scan time: 8.200 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]