Result of FASTA (omim) for
pF1KB4879
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4879, 810 aa
1>>>pF1KB4879 810 - 810 aa - 810 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7617+/-0.000412; mu= 9.8305+/- 0.026
mean_var=151.3420+/-30.238, 0's: 0 Z-trim(116.2): 306 B-trim: 0 in 0/59
Lambda= 0.104254
statistics sampled from 26934 (27254) to 26934 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.32), width: 16
Scan time: 12.980
The best scores are: opt bits E(85289)
XP_005245826 (OMIM: 130500,611804) PREDICTED: prot ( 810) 5275 805.9 0
XP_005245827 (OMIM: 130500,611804) PREDICTED: prot ( 809) 5258 803.3 0
XP_016856080 (OMIM: 130500,611804) PREDICTED: prot ( 733) 4440 680.3 8.3e-195
XP_016856074 (OMIM: 130500,611804) PREDICTED: prot ( 977) 4441 680.5 9.4e-195
XP_011539264 (OMIM: 130500,611804) PREDICTED: prot ( 977) 4441 680.5 9.4e-195
XP_005245831 (OMIM: 130500,611804) PREDICTED: prot ( 767) 4437 679.8 1.2e-194
XP_016856081 (OMIM: 130500,611804) PREDICTED: prot ( 732) 4423 677.7 4.9e-194
XP_016856072 (OMIM: 130500,611804) PREDICTED: prot ( 976) 4423 677.8 6.1e-194
XP_005245821 (OMIM: 130500,611804) PREDICTED: prot ( 831) 4075 625.4 3.1e-178
XP_005245822 (OMIM: 130500,611804) PREDICTED: prot ( 829) 4066 624.1 7.8e-178
NP_001159477 (OMIM: 130500,611804) protein 4.1 iso ( 864) 4061 623.3 1.4e-177
XP_005245818 (OMIM: 130500,611804) PREDICTED: prot ( 864) 4061 623.3 1.4e-177
XP_016856075 (OMIM: 130500,611804) PREDICTED: prot ( 841) 4054 622.3 2.8e-177
XP_005245825 (OMIM: 130500,611804) PREDICTED: prot ( 821) 4049 621.5 4.6e-177
NP_001159478 (OMIM: 130500,611804) protein 4.1 iso ( 720) 4043 620.6 7.7e-177
XP_011539267 (OMIM: 130500,611804) PREDICTED: prot ( 769) 4043 620.6 8.1e-177
XP_006710502 (OMIM: 130500,611804) PREDICTED: prot ( 876) 4044 620.8 8.1e-177
XP_005245830 (OMIM: 130500,611804) PREDICTED: prot ( 782) 4043 620.6 8.2e-177
XP_005245829 (OMIM: 130500,611804) PREDICTED: prot ( 787) 4043 620.6 8.3e-177
XP_011539265 (OMIM: 130500,611804) PREDICTED: prot ( 828) 4043 620.6 8.6e-177
XP_005245820 (OMIM: 130500,611804) PREDICTED: prot ( 850) 4043 620.6 8.8e-177
XP_005245817 (OMIM: 130500,611804) PREDICTED: prot ( 881) 4043 620.6 9.1e-177
XP_005245814 (OMIM: 130500,611804) PREDICTED: prot ( 979) 4043 620.7 9.9e-177
XP_011539263 (OMIM: 130500,611804) PREDICTED: prot ( 996) 4043 620.7 1e-176
XP_005245810 (OMIM: 130500,611804) PREDICTED: prot (1014) 4043 620.7 1e-176
XP_011539261 (OMIM: 130500,611804) PREDICTED: prot (1017) 4043 620.7 1e-176
XP_011539260 (OMIM: 130500,611804) PREDICTED: prot (1018) 4043 620.7 1e-176
XP_006710497 (OMIM: 130500,611804) PREDICTED: prot (1026) 4043 620.7 1e-176
XP_016856073 (OMIM: 130500,611804) PREDICTED: prot (1031) 4043 620.7 1e-176
XP_011539258 (OMIM: 130500,611804) PREDICTED: prot (1031) 4043 620.7 1e-176
XP_011539262 (OMIM: 130500,611804) PREDICTED: prot ( 998) 4040 620.2 1.4e-176
XP_016856077 (OMIM: 130500,611804) PREDICTED: prot ( 781) 4026 618.0 4.8e-176
XP_016856076 (OMIM: 130500,611804) PREDICTED: prot ( 786) 4026 618.0 4.9e-176
XP_011539259 (OMIM: 130500,611804) PREDICTED: prot (1030) 4026 618.1 6.1e-176
NP_001159479 (OMIM: 130500,611804) protein 4.1 iso ( 601) 3925 602.8 1.5e-171
NP_976218 (OMIM: 130500,611804) protein 4.1 isofor ( 775) 3565 548.7 3.6e-155
XP_016856078 (OMIM: 130500,611804) PREDICTED: prot ( 775) 3565 548.7 3.6e-155
XP_016856079 (OMIM: 130500,611804) PREDICTED: prot ( 774) 3548 546.1 2.1e-154
XP_016856092 (OMIM: 130500,611804) PREDICTED: prot ( 524) 3090 477.1 8.4e-134
XP_016856085 (OMIM: 130500,611804) PREDICTED: prot ( 768) 3091 477.4 1e-133
XP_016856093 (OMIM: 130500,611804) PREDICTED: prot ( 523) 3073 474.6 4.9e-133
XP_016856086 (OMIM: 130500,611804) PREDICTED: prot ( 767) 3073 474.7 6.7e-133
NP_004428 (OMIM: 130500,611804) protein 4.1 isofor ( 588) 2727 422.6 2.5e-117
XP_016856089 (OMIM: 130500,611804) PREDICTED: prot ( 573) 2693 417.5 8.5e-116
XP_016856088 (OMIM: 130500,611804) PREDICTED: prot ( 578) 2693 417.5 8.6e-116
XP_016856087 (OMIM: 130500,611804) PREDICTED: prot ( 619) 2693 417.5 9.1e-116
NP_976217 (OMIM: 130500,611804) protein 4.1 isofor ( 641) 2693 417.5 9.3e-116
XP_016856084 (OMIM: 130500,611804) PREDICTED: prot ( 787) 2693 417.5 1.1e-115
XP_011539266 (OMIM: 130500,611804) PREDICTED: prot ( 822) 2693 417.6 1.1e-115
XP_016856083 (OMIM: 130500,611804) PREDICTED: prot ( 789) 2690 417.1 1.5e-115
>>XP_005245826 (OMIM: 130500,611804) PREDICTED: protein (810 aa)
initn: 5275 init1: 5275 opt: 5275 Z-score: 4296.5 bits: 805.9 E(85289): 0
Smith-Waterman score: 5275; 99.9% identity (99.9% similar) in 810 aa overlap (1-810:1-810)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
730 740 750 760 770 780
790 800 810
pF1KB4 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
::::::::::::::::::::::::::::::
XP_005 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
790 800 810
>>XP_005245827 (OMIM: 130500,611804) PREDICTED: protein (809 aa)
initn: 3597 init1: 3597 opt: 5258 Z-score: 4282.7 bits: 803.3 E(85289): 0
Smith-Waterman score: 5258; 99.8% identity (99.8% similar) in 810 aa overlap (1-810:1-809)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSLDGAA-VDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590
610 620 630 640 650 660
pF1KB4 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
720 730 740 750 760 770
790 800 810
pF1KB4 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
::::::::::::::::::::::::::::::
XP_005 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
780 790 800
>>XP_016856080 (OMIM: 130500,611804) PREDICTED: protein (733 aa)
initn: 4437 init1: 4437 opt: 4440 Z-score: 3618.4 bits: 680.3 E(85289): 8.3e-195
Smith-Waterman score: 4440; 98.5% identity (98.8% similar) in 687 aa overlap (1-687:1-684)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
:::::::::::::: :: .: :.
XP_016 RTLNINGQIPTGEG---VKKTSVLPSERKVGGPESPSYFLPDTYHLGVCKEPVLNFQTDQ
670 680 690 700 710
>>XP_016856074 (OMIM: 130500,611804) PREDICTED: protein (977 aa)
initn: 5261 init1: 4437 opt: 4441 Z-score: 3617.4 bits: 680.5 E(85289): 9.4e-195
Smith-Waterman score: 4446; 90.8% identity (94.6% similar) in 758 aa overlap (1-758:1-746)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
:::::::::::::: :: .: :. : : ... ..:: ... .. .:.
XP_016 RTLNINGQIPTGEG---VKKTSVLPSER----KVGGP-ESINGIRTEEVAVVTKGPSTNP
670 680 690 700 710
730 740 750 760 770 780
pF1KB4 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
.: : ... :.. .:.. .. . . :..:
XP_016 DSEWEGP----KHSVVPSKSQMTTSSESLQSFAFGSLSISSKETEEKEEGAAGYLDIKEM
720 730 740 750 760
790 800 810
pF1KB4 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
XP_016 PRGPTGGCIGVEEQASALKFSVTPASCQLQPGVKKAESSEEHVTPGEPPGKQNGSFLDFH
770 780 790 800 810 820
>--
initn: 886 init1: 838 opt: 849 Z-score: 697.6 bits: 140.3 E(85289): 4.1e-32
Smith-Waterman score: 849; 90.9% identity (95.5% similar) in 154 aa overlap (660-810:824-977)
630 640 650 660 670 680
pF1KB4 SISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQIPT---GEGPPLVKTQTVTIS
: .....:.:: . ::::::::::::
XP_016 SCQLQPGVKKAESSEEHVTPGEPPGKQNGSFLDFHVGNQFPTLIRSFQPPLVKTQTVTIS
800 810 820 830 840 850
690 700 710 720 730 740
pF1KB4 DNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTT
860 870 880 890 900 910
750 760 770 780 790 800
pF1KB4 TQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE
920 930 940 950 960 970
810
pF1KB4 IADE
::::
XP_016 IADE
>>XP_011539264 (OMIM: 130500,611804) PREDICTED: protein (977 aa)
initn: 5261 init1: 4437 opt: 4441 Z-score: 3617.4 bits: 680.5 E(85289): 9.4e-195
Smith-Waterman score: 4446; 90.8% identity (94.6% similar) in 758 aa overlap (1-758:1-746)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
:::::::::::::: :: .: :. : : ... ..:: ... .. .:.
XP_011 RTLNINGQIPTGEG---VKKTSVLPSER----KVGGP-ESINGIRTEEVAVVTKGPSTNP
670 680 690 700 710
730 740 750 760 770 780
pF1KB4 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
.: : ... :.. .:.. .. . . :..:
XP_011 DSEWEGP----KHSVVPSKSQMTTSSESLQSFAFGSLSISSKETEEKEEGAAGYLDIKEM
720 730 740 750 760
790 800 810
pF1KB4 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
XP_011 PRGPTGGCIGVEEQASALKFSVTPASCQLQPGVKKAESSEEHVTPGEPPGKQNGSFLDFH
770 780 790 800 810 820
>--
initn: 886 init1: 838 opt: 849 Z-score: 697.6 bits: 140.3 E(85289): 4.1e-32
Smith-Waterman score: 849; 90.9% identity (95.5% similar) in 154 aa overlap (660-810:824-977)
630 640 650 660 670 680
pF1KB4 SISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQIPT---GEGPPLVKTQTVTIS
: .....:.:: . ::::::::::::
XP_011 SCQLQPGVKKAESSEEHVTPGEPPGKQNGSFLDFHVGNQFPTLIRSFQPPLVKTQTVTIS
800 810 820 830 840 850
690 700 710 720 730 740
pF1KB4 DNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTT
860 870 880 890 900 910
750 760 770 780 790 800
pF1KB4 TQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE
920 930 940 950 960 970
810
pF1KB4 IADE
::::
XP_011 IADE
>>XP_005245831 (OMIM: 130500,611804) PREDICTED: protein (767 aa)
initn: 4997 init1: 4437 opt: 4437 Z-score: 3615.7 bits: 679.8 E(85289): 1.2e-194
Smith-Waterman score: 4915; 94.6% identity (94.6% similar) in 810 aa overlap (1-810:1-767)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
:::::::::::::: :::
XP_005 RTLNINGQIPTGEG-------------------------------------------TDD
670
730 740 750 760 770 780
pF1KB4 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
680 690 700 710 720 730
790 800 810
pF1KB4 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
::::::::::::::::::::::::::::::
XP_005 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
740 750 760
>>XP_016856081 (OMIM: 130500,611804) PREDICTED: protein (732 aa)
initn: 3597 init1: 3597 opt: 4423 Z-score: 3604.6 bits: 677.7 E(85289): 4.9e-194
Smith-Waterman score: 4423; 98.4% identity (98.7% similar) in 687 aa overlap (1-687:1-683)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLDGAA-VDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590
610 620 630 640 650 660
pF1KB4 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
:::::::::::::: :: .: :.
XP_016 RTLNINGQIPTGEG---VKKTSVLPSERKVGGPESPSYFLPDTYHLGVCKEPVLNFQTDQ
660 670 680 690 700 710
>>XP_016856072 (OMIM: 130500,611804) PREDICTED: protein (976 aa)
initn: 4421 init1: 3597 opt: 4423 Z-score: 3602.8 bits: 677.8 E(85289): 6.1e-194
Smith-Waterman score: 4429; 90.6% identity (94.5% similar) in 758 aa overlap (1-758:1-745)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLDGAA-VDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590
610 620 630 640 650 660
pF1KB4 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 RTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQTDD
:::::::::::::: :: .: :. : : ... ..:: ... .. .:.
XP_016 RTLNINGQIPTGEG---VKKTSVLPSER----KVGGP-ESINGIRTEEVAVVTKGPSTNP
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 NSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVL
.: : ... :.. .:.. .. . . :..:
XP_016 DSEWEGP----KHSVVPSKSQMTTSSESLQSFAFGSLSISSKETEEKEEGAAGYLDIKEM
720 730 740 750 760
790 800 810
pF1KB4 VQAIKEAKEQHPDMSVTKVVVHQETEIADE
XP_016 PRGPTGGCIGVEEQASALKFSVTPASCQLQPGVKKAESSEEHVTPGEPPGKQNGSFLDFH
770 780 790 800 810 820
>--
initn: 886 init1: 838 opt: 849 Z-score: 697.6 bits: 140.3 E(85289): 4.1e-32
Smith-Waterman score: 849; 90.9% identity (95.5% similar) in 154 aa overlap (660-810:823-976)
630 640 650 660 670 680
pF1KB4 SISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQIPT---GEGPPLVKTQTVTIS
: .....:.:: . ::::::::::::
XP_016 SCQLQPGVKKAESSEEHVTPGEPPGKQNGSFLDFHVGNQFPTLIRSFQPPLVKTQTVTIS
800 810 820 830 840 850
690 700 710 720 730 740
pF1KB4 DNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNANAVKSEIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTT
860 870 880 890 900 910
750 760 770 780 790 800
pF1KB4 TQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETE
920 930 940 950 960 970
810
pF1KB4 IADE
::::
XP_016 IADE
>>XP_005245821 (OMIM: 130500,611804) PREDICTED: protein (831 aa)
initn: 4037 init1: 4037 opt: 4075 Z-score: 3320.9 bits: 625.4 E(85289): 3.1e-178
Smith-Waterman score: 5223; 97.4% identity (97.4% similar) in 831 aa overlap (1-810:1-831)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590 600
610 620 630
pF1KB4 EPPEQAEPEPTEAWK---------------------DLDKSQEEIKKHHASISELKKNFM
::::::::::::::: ::::::::::::::::::::::::
XP_005 EPPEQAEPEPTEAWKKKRERLDGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFM
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB4 ESVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTK
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB4 DVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISE
730 740 750 760 770 780
760 770 780 790 800 810
pF1KB4 TRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE
790 800 810 820 830
>>XP_005245822 (OMIM: 130500,611804) PREDICTED: protein (829 aa)
initn: 4037 init1: 4037 opt: 4066 Z-score: 3313.6 bits: 624.1 E(85289): 7.8e-178
Smith-Waterman score: 5227; 97.6% identity (97.6% similar) in 829 aa overlap (1-810:1-829)
10 20 30 40 50 60
pF1KB4 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEELREDPDFEIKEGEGLEECS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KELEEKVMELHKSCRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED
550 560 570 580 590 600
610 620 630 640
pF1KB4 EPPEQAEPEPTEAWK-------------------DLDKSQEEIKKHHASISELKKNFMES
::::::::::::::: ::::::::::::::::::::::::::
XP_005 EPPEQAEPEPTEAWKVEKTHIEVTVPTSNGDQTQDLDKSQEEIKKHHASISELKKNFMES
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 VPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDV
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 PIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTTTQITKTVKGGISETR
730 740 750 760 770 780
770 780 790 800 810
pF1KB4 IEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE
790 800 810 820
810 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:46:12 2016 done: Fri Nov 4 22:46:14 2016
Total Scan time: 12.980 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]