FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4902, 744 aa 1>>>pF1KB4902 744 - 744 aa - 744 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6514+/-0.00117; mu= 17.9931+/- 0.071 mean_var=73.8193+/-14.696, 0's: 0 Z-trim(102.0): 60 B-trim: 0 in 0/49 Lambda= 0.149276 statistics sampled from 6716 (6774) to 6716 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.565), E-opt: 0.2 (0.208), width: 16 Scan time: 3.880 The best scores are: opt bits E(32554) CCDS42354.1 NSF gene_id:4905|Hs108|chr17 ( 744) 4824 1049.1 0 CCDS6573.1 VCP gene_id:7415|Hs108|chr9 ( 806) 540 126.6 1.6e-28 CCDS56043.1 PSMC5 gene_id:5705|Hs108|chr17 ( 398) 472 111.8 2.2e-24 CCDS11645.1 PSMC5 gene_id:5705|Hs108|chr17 ( 406) 472 111.8 2.2e-24 CCDS81837.1 PSMC1 gene_id:5700|Hs108|chr14 ( 367) 463 109.8 7.8e-24 CCDS32139.1 PSMC1 gene_id:5700|Hs108|chr14 ( 440) 463 109.8 9.1e-24 CCDS9710.2 PSMC6 gene_id:5706|Hs108|chr14 ( 403) 450 107.0 5.9e-23 CCDS11859.1 AFG3L2 gene_id:10939|Hs108|chr18 ( 797) 442 105.5 3.5e-22 CCDS5731.1 PSMC2 gene_id:5701|Hs108|chr7 ( 433) 437 104.2 4.4e-22 CCDS46076.1 PSMC4 gene_id:5704|Hs108|chr19 ( 387) 433 103.4 7.2e-22 CCDS12547.1 PSMC4 gene_id:5704|Hs108|chr19 ( 418) 433 103.4 7.7e-22 CCDS3730.1 SPATA5 gene_id:166378|Hs108|chr4 ( 893) 432 103.3 1.7e-21 CCDS7935.1 PSMC3 gene_id:5702|Hs108|chr11 ( 439) 426 101.9 2.3e-21 CCDS10977.1 SPG7 gene_id:6687|Hs108|chr16 ( 795) 412 99.0 3e-20 CCDS46227.1 ATAD2B gene_id:54454|Hs108|chr2 (1458) 405 97.6 1.4e-19 CCDS6343.1 ATAD2 gene_id:29028|Hs108|chr8 (1390) 390 94.4 1.3e-18 CCDS4877.1 PEX6 gene_id:5190|Hs108|chr6 ( 980) 378 91.7 5.8e-18 CCDS64710.1 PEX1 gene_id:5189|Hs108|chr7 (1226) 337 82.9 3.2e-15 CCDS5627.1 PEX1 gene_id:5189|Hs108|chr7 (1283) 337 83.0 3.3e-15 CCDS58062.1 NVL gene_id:4931|Hs108|chr1 ( 667) 330 81.3 5.4e-15 CCDS1542.1 NVL gene_id:4931|Hs108|chr1 ( 750) 330 81.3 6e-15 CCDS58063.1 NVL gene_id:4931|Hs108|chr1 ( 765) 330 81.3 6.1e-15 CCDS1541.1 NVL gene_id:4931|Hs108|chr1 ( 856) 330 81.4 6.7e-15 CCDS81877.1 SPATA5L1 gene_id:79029|Hs108|chr15 ( 620) 307 76.3 1.6e-13 CCDS10123.1 SPATA5L1 gene_id:79029|Hs108|chr15 ( 753) 307 76.4 1.9e-13 CCDS58072.1 YME1L1 gene_id:10730|Hs108|chr10 ( 683) 279 70.3 1.1e-11 CCDS7151.1 YME1L1 gene_id:10730|Hs108|chr10 ( 716) 279 70.3 1.2e-11 CCDS7152.1 YME1L1 gene_id:10730|Hs108|chr10 ( 773) 279 70.3 1.2e-11 >>CCDS42354.1 NSF gene_id:4905|Hs108|chr17 (744 aa) initn: 4824 init1: 4824 opt: 4824 Z-score: 5612.5 bits: 1049.1 E(32554): 0 Smith-Waterman score: 4824; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744) 10 20 30 40 50 60 pF1KB4 MAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAGRSMQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 AFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 AFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 FIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FIQQFNNQAFSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 SQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 VEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 LASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 LEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 VVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 FSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQM 670 680 690 700 710 720 730 740 pF1KB4 DPEYRVRKFLALLREEGASPLDFD :::::::::::::::::::::::: CCDS42 DPEYRVRKFLALLREEGASPLDFD 730 740 >>CCDS6573.1 VCP gene_id:7415|Hs108|chr9 (806 aa) initn: 586 init1: 247 opt: 540 Z-score: 625.8 bits: 126.6 E(32554): 1.6e-28 Smith-Waterman score: 658; 34.4% identity (61.6% similar) in 425 aa overlap (242-652:227-629) 220 230 240 250 260 270 pF1KB4 DWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLAR : . . .: : .::::::::: ::::.:: CCDS65 SLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIAR 200 210 220 230 240 250 280 290 300 310 320 330 pF1KB4 QIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEID ... .: ..:::::..: .::::.:.:: : .::. .. ::..::.: CCDS65 AVANETGAFFF-LINGPEIMSKLAGESESNLRKAFEEAEK--------NAPAIIFIDELD 260 270 280 290 300 340 350 360 370 380 390 pF1KB4 AICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEV :: .: . : :. .:.:::. .::..: ...:.. ::::. :: :: : ::.. CCDS65 AIAPKREKTHGE--VERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDR 310 320 330 340 350 360 400 410 420 430 440 450 pF1KB4 KMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQST ...::.:: :::.::.::: :. :. :::....: ::.. ::.: .: : CCDS65 EVDIGIPDATGRLEILQIHTKNMK----LADDVDLEQVANETHGHVGADLAALCSEAALQ 370 380 390 400 410 420 460 470 480 490 500 pF1KB4 AMNRHIK-ASTKVE-VDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIK :. ... . . : .: : .:: :: :: .: .. :. . . . . : CCDS65 AIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGG 430 440 450 460 470 480 510 520 530 540 550 560 pF1KB4 WGDPVTRVLDDGELLVQQTKNSDR------TPLVSVLLEGPPHSGKTALAAKIAEESNFP : : : :. ::. ... :. :: .::. ::: ::: :: ::.: . CCDS65 LED-VKRELQ--ELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQAN 490 500 510 520 530 570 580 590 600 610 pF1KB4 FIKICSPDKM-IGFSETAKCQAMKKIFDDAYKSQLSCVVV-DDIERLLDY----VPIGPR ::.: .:. . . :.:. ...::: : .. ::. :... . . : CCDS65 FISIKGPELLTMWFGESEA--NVREIFDKARQAA-PCVLFFDELDSIAKARGGNIGDGGG 540 550 560 570 580 590 620 630 640 650 660 670 pF1KB4 FSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLL .. :.. .:. . . ....:::.:.: :.. CCDS65 AADRVINQILTEMDGMSTK-KNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRV 600 610 620 630 640 650 680 690 700 710 720 730 pF1KB4 EALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEG CCDS65 AILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQ 660 670 680 690 700 710 >>CCDS56043.1 PSMC5 gene_id:5705|Hs108|chr17 (398 aa) initn: 403 init1: 206 opt: 472 Z-score: 551.3 bits: 111.8 E(32554): 2.2e-24 Smith-Waterman score: 524; 33.2% identity (65.1% similar) in 364 aa overlap (116-474:49-384) 90 100 110 120 130 140 pF1KB4 DKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLF .. : .: ...:. ::. .: ....: CCDS56 KIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGE-VVRAMDKK-- 20 30 40 50 60 70 150 160 170 180 190 200 pF1KB4 GLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENR .::: . : .:. .. ..:... :. : .::. . .. .:. : :. CCDS56 KVLVK----VHP---EGKFVVDVDKNIDINDVTPNCRVAL-RNDSYTLHKILPNKVDPLV 80 90 100 110 120 210 220 230 240 250 260 pF1KB4 QSIIN---PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPP . .. :: ..: ::::::....: .... : ::. : .: . ::.:::::: CCDS56 SLMMVEKVPDSTYEM--IGGLDKQIKEI-KEVIELPVKHPELFEALGIAQPKGVLLYGPP 130 140 150 160 170 180 270 280 290 300 310 320 pF1KB4 GCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGL : ::::::: ... . .: .: :...:..::. .:.::. :.:. : : CCDS56 GTGKTLLARAVAHHTDCTFIRV-SGSELVQKFIGEGARMVRELFVMAREH-----APS-- 190 200 210 220 230 330 340 350 360 370 380 pF1KB4 HIIIFDEIDAICKQR--GSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLID ::..::::.: ..: :. .:.. :. :.. .::...:: : .:: :: ::: :..: CCDS56 -IIFMDEIDSIGSSRLEGGSGGDSEVQRTML-ELLNQLDGFEATKNIKVIMATNRIDILD 240 250 260 270 280 290 390 400 410 420 430 440 pF1KB4 EALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAE :::::::.. :.:. :.:..::.::.::. .: :. ......: . :::: CCDS56 SALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMN----LTRGINLRKIAELMPGASGAE 300 310 320 330 340 350 450 460 470 480 490 500 pF1KB4 LEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYA ..:. : :. .. :. . .: :. .: CCDS56 VKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK 360 370 380 390 510 520 530 540 550 560 pF1KB4 SYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEES >>CCDS11645.1 PSMC5 gene_id:5705|Hs108|chr17 (406 aa) initn: 403 init1: 206 opt: 472 Z-score: 551.2 bits: 111.8 E(32554): 2.2e-24 Smith-Waterman score: 524; 33.2% identity (65.1% similar) in 364 aa overlap (116-474:57-392) 90 100 110 120 130 140 pF1KB4 DKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNEKLF .. : .: ...:. ::. .: ....: CCDS11 KIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGE-VVRAMDKK-- 30 40 50 60 70 80 150 160 170 180 190 200 pF1KB4 GLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENR .::: . : .:. .. ..:... :. : .::. . .. .:. : :. CCDS11 KVLVK----VHP---EGKFVVDVDKNIDINDVTPNCRVAL-RNDSYTLHKILPNKVDPLV 90 100 110 120 130 210 220 230 240 250 260 pF1KB4 QSIIN---PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPP . .. :: ..: ::::::....: .... : ::. : .: . ::.:::::: CCDS11 SLMMVEKVPDSTYEM--IGGLDKQIKEI-KEVIELPVKHPELFEALGIAQPKGVLLYGPP 140 150 160 170 180 190 270 280 290 300 310 320 pF1KB4 GCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGL : ::::::: ... . .: .: :...:..::. .:.::. :.:. : : CCDS11 GTGKTLLARAVAHHTDCTFIRV-SGSELVQKFIGEGARMVRELFVMAREH-----APS-- 200 210 220 230 240 330 340 350 360 370 380 pF1KB4 HIIIFDEIDAICKQR--GSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLID ::..::::.: ..: :. .:.. :. :.. .::...:: : .:: :: ::: :..: CCDS11 -IIFMDEIDSIGSSRLEGGSGGDSEVQRTML-ELLNQLDGFEATKNIKVIMATNRIDILD 250 260 270 280 290 300 390 400 410 420 430 440 pF1KB4 EALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAE :::::::.. :.:. :.:..::.::.::. .: :. ......: . :::: CCDS11 SALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMN----LTRGINLRKIAELMPGASGAE 310 320 330 340 350 450 460 470 480 490 500 pF1KB4 LEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYA ..:. : :. .. :. . .: :. .: CCDS11 VKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK 360 370 380 390 400 510 520 530 540 550 560 pF1KB4 SYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEES >>CCDS81837.1 PSMC1 gene_id:5700|Hs108|chr14 (367 aa) initn: 433 init1: 199 opt: 463 Z-score: 541.3 bits: 109.8 E(32554): 7.8e-24 Smith-Waterman score: 487; 36.9% identity (69.4% similar) in 255 aa overlap (220-471:114-350) 190 200 210 220 230 240 pF1KB4 NSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMG :::::.....: ... . :: :.:: CCDS81 HAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEI-KESVELPLTHPEYYEEMG 90 100 110 120 130 140 250 260 270 280 290 300 pF1KB4 CKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADA : ::..:::::: ::::::. .... .: .:: : :...::.:.. .:.:: : CCDS81 IKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVV-GSELIQKYLGDGPKLVRELFRVA 150 160 170 180 190 200 310 320 330 340 350 360 pF1KB4 EEEQRRLGANSGLHIIIFDEIDAICKQR--GSMAGSTGVHDTVVNQLLSKIDGVEQLNNI ::. : : :...:::::: .: .. .: .. :.. .::...:: .. ... CCDS81 EEH-----APS---IVFIDEIDAIGTKRYDSNSGGEREIQRTML-ELLNQLDGFDSRGDV 210 220 230 240 250 370 380 390 400 410 420 pF1KB4 LVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIK :: ::: . .: ::.::::.. :.:. ::::: . .:..:::.:: :. :: . CCDS81 KVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMT----LADDVTLD 260 270 280 290 300 430 440 450 460 470 480 pF1KB4 ELAVETKNFSGAELEGLVRAAQSTAM-NRHIKASTKVEVDMEKAESLQVTRGDFLASLEN .: . ..:::..... : :. .:..:.... :..:.. CCDS81 DLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE---DFKKSKENVLYKKQEGTPEGL 310 320 330 340 350 360 490 500 510 520 530 540 pF1KB4 DIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPH CCDS81 YL >>CCDS32139.1 PSMC1 gene_id:5700|Hs108|chr14 (440 aa) initn: 433 init1: 199 opt: 463 Z-score: 540.1 bits: 109.8 E(32554): 9.1e-24 Smith-Waterman score: 487; 36.9% identity (69.4% similar) in 255 aa overlap (220-471:187-423) 190 200 210 220 230 240 pF1KB4 NSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMG :::::.....: ... . :: :.:: CCDS32 HAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEI-KESVELPLTHPEYYEEMG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 CKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADA : ::..:::::: ::::::. .... .: .:: : :...::.:.. .:.:: : CCDS32 IKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVV-GSELIQKYLGDGPKLVRELFRVA 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 EEEQRRLGANSGLHIIIFDEIDAICKQR--GSMAGSTGVHDTVVNQLLSKIDGVEQLNNI ::. : : :...:::::: .: .. .: .. :.. .::...:: .. ... CCDS32 EEH-----APS---IVFIDEIDAIGTKRYDSNSGGEREIQRTML-ELLNQLDGFDSRGDV 280 290 300 310 320 370 380 390 400 410 420 pF1KB4 LVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIK :: ::: . .: ::.::::.. :.:. ::::: . .:..:::.:: :. :: . CCDS32 KVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMT----LADDVTLD 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB4 ELAVETKNFSGAELEGLVRAAQSTAM-NRHIKASTKVEVDMEKAESLQVTRGDFLASLEN .: . ..:::..... : :. .:..:.... :..:.. CCDS32 DLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNE---DFKKSKENVLYKKQEGTPEGL 390 400 410 420 430 490 500 510 520 530 540 pF1KB4 DIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPH CCDS32 YL 440 >>CCDS9710.2 PSMC6 gene_id:5706|Hs108|chr14 (403 aa) initn: 427 init1: 215 opt: 450 Z-score: 525.6 bits: 107.0 E(32554): 5.9e-23 Smith-Waterman score: 467; 37.1% identity (67.8% similar) in 264 aa overlap (220-472:149-396) 190 200 210 220 230 240 pF1KB4 NSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMG ::::.... .. :... . ::. ...: CCDS97 LTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIREL-REVIELPLTNPELFQRVG 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB4 CKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADA :: ::::::: ::::::: ....:. :::.. :..::.::: ::..: : CCDS97 IIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSS-IVDKYIGESARLIREMFNYA 180 190 200 210 220 230 310 320 330 340 350 360 pF1KB4 EEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTG--VHDTVVNQLLSKIDGVEQLNNI ...: ::..:::::: .: : . :. .. :.. .::...:: . :. . CCDS97 RDHQP--------CIIFMDEIDAIGGRRFSEGTSADREIQRTLM-ELLNQMDGFDTLHRV 240 250 260 270 280 370 380 390 400 410 420 pF1KB4 LVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIK .: ::::: .: ::::::::. :..: ::.:..::.::.::.. . : ...: . CCDS97 KMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKH----GEIDYE 290 300 310 320 330 340 430 440 450 460 470 pF1KB4 ELAVETKNFSGAELEGL--------VRAAQSTAMNRH-IKASTKVEVDMEKAESLQVTRG .. . .:.::.:... .:: .. .... .:: :: .: .: :: CCDS97 AIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKV-ADSKKLESKLDYKP 350 360 370 380 390 400 480 490 500 510 520 530 pF1KB4 DFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVS CCDS97 V >>CCDS11859.1 AFG3L2 gene_id:10939|Hs108|chr18 (797 aa) initn: 252 init1: 252 opt: 442 Z-score: 511.8 bits: 105.5 E(32554): 3.5e-22 Smith-Waterman score: 444; 26.7% identity (55.2% similar) in 513 aa overlap (203-700:293-762) 180 190 200 210 220 230 pF1KB4 EVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFR :. .... . . . ..: .. .:.. CCDS11 IIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIME 270 280 290 300 310 320 240 250 260 270 280 290 pF1KB4 RAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKV-VNGPEIL :.. . :. ...: : :: .: :::: ::::::. . :. : . :.: :.: CCDS11 --FVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANV--PFITVSGSEFL 330 340 350 360 370 300 310 320 330 340 350 pF1KB4 NKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMA-GSTGVHDTV . .:: . : .: ::: : : .: :...:::::. ..:: :. . .... CCDS11 EMFVGVGPARVRDLFALA-----RKNAPC---ILFIDEIDAVGRKRGRGNFGGQSEQENT 380 390 400 410 420 430 360 370 380 390 400 410 pF1KB4 VNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIH .:::: ..:: . .:..... :::::..: :::::::.. .. :: :: ::: .:...: CCDS11 LNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVH 440 450 460 470 480 490 420 430 440 450 460 470 pF1KB4 TARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKA .. . : : ..:: : .::::.. .. : : ::.. : . . .:.: CCDS11 LRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAA-RHLSDSIN-QKHFEQA 500 510 520 530 540 480 490 500 510 520 pF1KB4 ESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNG--IIKW----GDPVTRV--LDDGE . : ...::. . .. ... ..: : . : .::. .: . :. CCDS11 ----IER--VIGGLEKKTQ-VLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGK 550 560 570 580 590 600 530 540 550 560 570 580 pF1KB4 LL--VQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETA : .: . . ::. .:.....:: : : . : . ...: CCDS11 GLGYAQYLPKEQYLYTKEQLLD----RMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSA 610 620 630 640 650 590 600 610 620 630 pF1KB4 KCQAMKKIFDDAYKSQLSCVVVDDIERLLDYV---PIGPRFSNLVLQALLVLLKKAPPQG : .. ... .:.: :. : :.: : . . :. . . .:.. : . CCDS11 YAQIVQFGMNEKV-GQISF----DLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRT 660 670 680 690 700 710 640 650 660 670 680 690 pF1KB4 RKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQ :: : .. :: . .: . . : . .:::: :..: . CCDS11 VALL---TEKKADVEKVALLL--LEKEVLDKN--------DMVELLGPRPFAEKSTYEEF 720 730 740 750 700 710 720 730 740 pF1KB4 VKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGASPLDFD :.: CCDS11 VEGTGSLDEDTSLPEGLKDWNKEREKEKEEPPGEKVAN 760 770 780 790 >>CCDS5731.1 PSMC2 gene_id:5701|Hs108|chr7 (433 aa) initn: 421 init1: 209 opt: 437 Z-score: 510.0 bits: 104.2 E(32554): 4.4e-22 Smith-Waterman score: 446; 34.2% identity (62.9% similar) in 275 aa overlap (211-483:170-426) 190 200 210 220 230 240 pF1KB4 SQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVF :: .. .:: :: . .:.. . .. CCDS57 VGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYS--DVGGC-KEQIEKLREVVETPLL 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB4 PPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEA :: ..: . ::.::.:::: :::: :: ... .: .:. : :...:::::. CCDS57 HPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVI-GSELVQKYVGEGAR 200 210 220 230 240 250 310 320 330 340 350 pF1KB4 NIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR--GSMAGSTGVHDTVVNQLLSKI .:.:: :. .. : :.::::::: : . .:.. :. :.. .:.... CCDS57 MVRELFEMARTKKACL--------IFFDEIDAIGGARFDDGAGGDNEVQRTML-ELINQL 260 270 280 290 300 360 370 380 390 400 410 pF1KB4 DGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQ :: . .:: :. ::::: .: ::.:::::. :.:..::: .:: .:..::. : CCDS57 DGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMS--- 310 320 330 340 350 360 420 430 440 450 460 470 pF1KB4 LLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRG . :. .. :: : .:::.... : :. . : .:. . .: .... . . CCDS57 -VERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDF-LEAVNKVIKSYA 370 380 390 400 410 420 480 490 500 510 520 530 pF1KB4 DFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVS : :. CCDS57 KFSATPRYMTYN 430 >>CCDS46076.1 PSMC4 gene_id:5704|Hs108|chr19 (387 aa) initn: 364 init1: 170 opt: 433 Z-score: 506.1 bits: 103.4 E(32554): 7.2e-22 Smith-Waterman score: 462; 31.3% identity (62.9% similar) in 313 aa overlap (172-479:88-380) 150 160 170 180 190 200 pF1KB4 EKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKT :. :. :..::..: :. .... CCDS46 IGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVL--PPE 60 70 80 90 100 110 210 220 230 240 250 pF1KB4 KENRQSIINPDWNFEKM--GIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLY .. ... : . . : :::.: . ... :.: . :. .:.: .:.:.: CCDS46 ADSSIMMLTSDQKPDVMYADIGGMDIQKQEV-REAVELPLTHFELYKQIGIDPPRGVLMY 120 130 140 150 160 170 260 270 280 290 300 310 pF1KB4 GPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGAN ::::::::.::. ... .: .:: : :...::.::. .: .: ::. . CCDS46 GPPGCGKTMLAKAVAHHTTAAFIRVV-GSEFVQKYLGEGPRMVRDVF--------RLAKE 180 190 200 210 220 320 330 340 350 360 370 pF1KB4 SGLHIIIFDEIDAICKQR-GSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDL .. ::..:::::: .: ...:. . .. .::...:: .: :. :: ::: : CCDS46 NAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADT 230 240 250 260 270 280 380 390 400 410 420 430 pF1KB4 IDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSG .: ::::::::. :.:. :::.. . :. :..: :: .::... ... ..:: CCDS46 LDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMN----LSEEVDLEDYVARPDKISG 290 300 310 320 330 340 440 450 460 470 480 490 pF1KB4 AELEGLVRAAQSTAM--NRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQ :..... . . :. ::.: . :.::: . . . . CCDS46 ADINSICQESGMLAVRENRYIVLAK----DFEKAYKTVIKKDEQEHEFYK 350 360 370 380 500 510 520 530 540 550 pF1KB4 EDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKI 744 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:06:32 2016 done: Thu Nov 3 22:06:33 2016 Total Scan time: 3.880 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]