FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4940, 479 aa 1>>>pF1KB4940 479 - 479 aa - 479 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8312+/-0.000955; mu= -5.4583+/- 0.057 mean_var=423.4430+/-92.301, 0's: 0 Z-trim(117.4): 667 B-trim: 1064 in 1/54 Lambda= 0.062327 statistics sampled from 17370 (18168) to 17370 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.838), E-opt: 0.2 (0.558), width: 16 Scan time: 4.280 The best scores are: opt bits E(32554) CCDS6770.2 KLF4 gene_id:9314|Hs108|chr9 ( 479) 3406 320.2 3e-87 CCDS12343.1 KLF2 gene_id:10365|Hs108|chr19 ( 355) 823 87.8 2e-17 CCDS12285.1 KLF1 gene_id:10661|Hs108|chr19 ( 362) 684 75.3 1.2e-13 CCDS3444.1 KLF3 gene_id:51274|Hs108|chr4 ( 345) 582 66.1 6.6e-11 >>CCDS6770.2 KLF4 gene_id:9314|Hs108|chr9 (479 aa) initn: 3406 init1: 3406 opt: 3406 Z-score: 1679.9 bits: 320.2 E(32554): 3e-87 Smith-Waterman score: 3406; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479) 10 20 30 40 50 60 pF1KB4 MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 RPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 AATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 PTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 EYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 EYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 AAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 AAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 PPLHYQELMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 PPLHYQELMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTH 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 TGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF 430 440 450 460 470 >>CCDS12343.1 KLF2 gene_id:10365|Hs108|chr19 (355 aa) initn: 866 init1: 729 opt: 823 Z-score: 426.2 bits: 87.8 E(32554): 2e-17 Smith-Waterman score: 892; 44.7% identity (58.7% similar) in 380 aa overlap (118-478:5-354) 90 100 110 120 130 140 pF1KB4 LAPLPRRETEEFNDLLDLDFILSNSLTHPPESVAATVSSSASASSSSSPSSSGPASAPST : . . :. :: . . : . : . CCDS12 MALSEPILPSFSTFASPCRERGLQERWPRAEPES 10 20 30 150 160 170 180 190 200 pF1KB4 CSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPPPTAP-FNLADIND----VSPSGGFVAE . . . : .. : : : . : ::: : : . . .:.::.:.: CCDS12 GGTDDDLNSVLDFILSMGLDGLGAEAAPEPPPPPPPPAFYYPEPGAPPPYSAPAGGLVSE 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB4 LLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGSHPVV ::::::: : : .: :.:. :. :: .... ::. CCDS12 LLRPELD---------APLGPALHGRFL----LAPPGR------LVKAEPPEADGGGGYG 100 110 120 130 270 280 290 300 310 pF1KB4 VAPYNGGPPRTCPKIKQEAV----SSCTHLGAGPPLSNGHRPAAHDFP-LGRQLPSRTTP :: :: .:.:.. .:: . :: .:. : : : :. . :.: : CCDS12 CAPGLTRGPRG---LKREGAPGPAASCMR---GP---GGRPPPPPDTPPLSPDGPARL-P 140 150 160 170 180 320 330 340 350 360 pF1KB4 TLGLEEVLSSRDCHPALPLP-PGFHPHPGPNYPSF-LPDQMQPQV------PPLHYQELM . : . . :.. : ::.: : : :.: : :. . :: : CCDS12 APGPRASFPPPFGGPGFGAPGPGLHYAP-PAPPAFGLFDDAAAAAAALGLAPPAARGLLT 190 200 210 220 230 240 370 380 390 400 410 420 pF1KB4 PPGSCMPE-EPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHC ::.: . : :::::::::::::::::::.::::::::::::::::::::::::::::: CCDS12 PPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHC 250 260 270 280 290 300 430 440 450 460 470 pF1KB4 DWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF .:::::::::::::::::::::::::::::. :::::::::::::::::: CCDS12 NWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM 310 320 330 340 350 >>CCDS12285.1 KLF1 gene_id:10661|Hs108|chr19 (362 aa) initn: 815 init1: 633 opt: 684 Z-score: 358.6 bits: 75.3 E(32554): 1.2e-13 Smith-Waterman score: 687; 47.7% identity (61.5% similar) in 262 aa overlap (239-479:114-362) 210 220 230 240 250 260 pF1KB4 DPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGS---HPVVVAP :. :.:.... :: : : .:.. : CCDS12 GPEPGGAPQTCALAPSEASGAQYPPPPETLGAYAGGPGLVAGLLGSEDHSGWVRPALRAR 90 100 110 120 130 140 270 280 290 300 310 pF1KB4 YNG---GP---PRTCPKIKQEAVSSCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTL :: : :. : :.. .. : : :.:. : . : ..:. . CCDS12 APDAFVGPALAPAPAPEPKALALQP-VYPGPGAGSSGGYFPRT-----GLSVPAASGAPY 150 160 170 180 190 320 330 340 350 360 pF1KB4 GLEEVLSSRDCHPAL-PLPP---------GFH-PHPGP-NYPSFLPDQMQPQVPPLHYQE :: ::. .::. : : :.. : ::: . :::: : CCDS12 GL---LSG---YPAMYPAPQYQGHFQLFRGLQGPAPGPATSPSFLSCLGPGTVGTGLGGT 200 210 220 230 240 250 370 380 390 400 410 420 pF1KB4 LMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYH :: . : ::::::: ::: :.::: . ::::.:::::::::::::::::::: CCDS12 AEDPG-VIAETAPSKRGRRSWARKRQAAHTCAHPGCGKSYTKSSHLKAHLRTHTGEKPYA 260 270 280 290 300 310 430 440 450 460 470 pF1KB4 CDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF : :.::::.::::::::::::::::.:::.:: : ::::::::::::::::. CCDS12 CTWEGCGWRFARSDELTRHYRKHTGQRPFRCQLCPRAFSRSDHLALHMKRHL 320 330 340 350 360 >>CCDS3444.1 KLF3 gene_id:51274|Hs108|chr4 (345 aa) initn: 547 init1: 525 opt: 582 Z-score: 309.3 bits: 66.1 E(32554): 6.6e-11 Smith-Waterman score: 591; 38.7% identity (58.6% similar) in 292 aa overlap (207-478:58-342) 180 190 200 210 220 230 pF1KB4 SAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIP-PQQPQPPGGGLMG---KFVLK ...:: . .. .::..: :: . CCDS34 SMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQMEPVDLTVNKRSSPPSAGNSPSSLKFPSS 30 40 50 60 70 80 240 250 260 270 280 290 pF1KB4 ASLSAPGSEY--GSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGA ..:: . .:: . . : :: : .: : : . :: ...... : : . CCDS34 HRRASPGLSMPSSSPPIKKYSPPSP-GVQPFGV-PLSM-PPVMAAALSRHGIRSPGILPV 90 100 110 120 130 140 300 310 320 330 pF1KB4 GPPLSNGHRPAAHDFPLGRQLPSRTTPTLGLEEVLSSRDC-------HPA----LPLPPG :. .:. . : : .. . .:. :: . .: . . :: CCDS34 IQPVVV--QPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEPG 150 160 170 180 190 200 340 350 360 370 380 390 pF1KB4 FHPHPGPNYPSFL-PDQMQPQVPPLHY-QELMPPGSCMP-EEPKPKRGRRSWPRKRTATH ..:. :: . : :. :: :: : .: ..: : .. . ..: : CCDS34 IEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRI--H 210 220 230 240 250 260 400 410 420 430 440 450 pF1KB4 TCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPF ::: ::.:.:::::::::: :::::::::.: :.:: ::::::::::::.::::: .:: CCDS34 RCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPF 270 280 290 300 310 320 460 470 pF1KB4 QCQKCDRAFSRSDHLALHMKRHF :: :::.:::::::::: ::: CCDS34 QCPDCDRSFSRSDHLALHRKRHMLV 330 340 479 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:36:42 2016 done: Thu Nov 3 15:36:43 2016 Total Scan time: 4.280 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]