FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4940, 479 aa
1>>>pF1KB4940 479 - 479 aa - 479 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.7937+/-0.000405; mu= -9.7637+/- 0.025
mean_var=563.6114+/-127.902, 0's: 0 Z-trim(125.0): 936 B-trim: 2170 in 1/61
Lambda= 0.054024
statistics sampled from 46398 (47854) to 46398 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.839), E-opt: 0.2 (0.561), width: 16
Scan time: 12.820
The best scores are: opt bits E(85289)
NP_004226 (OMIM: 602253) Krueppel-like factor 4 is ( 479) 3406 280.0 9.9e-75
NP_001300981 (OMIM: 602253) Krueppel-like factor 4 ( 513) 2670 222.7 1.9e-57
NP_057354 (OMIM: 602016) Krueppel-like factor 2 [H ( 355) 823 78.5 3.3e-14
XP_011525944 (OMIM: 111150,600599,613566,613673) P ( 324) 684 67.7 5.6e-11
NP_006554 (OMIM: 111150,600599,613566,613673) Krue ( 362) 684 67.7 6.1e-11
XP_016863768 (OMIM: 609392) PREDICTED: Krueppel-li ( 320) 582 59.7 1.4e-08
NP_057615 (OMIM: 609392) Krueppel-like factor 3 [H ( 345) 582 59.8 1.5e-08
XP_011529061 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 572 59.0 2.5e-08
XP_016884739 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 572 59.0 2.5e-08
NP_001311034 (OMIM: 300286) Krueppel-like factor 8 ( 356) 564 58.4 3.9e-08
XP_005262036 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 564 58.4 3.9e-08
NP_009181 (OMIM: 300286) Krueppel-like factor 8 is ( 359) 564 58.4 3.9e-08
XP_005262034 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 564 58.4 3.9e-08
NP_001311031 (OMIM: 300286) Krueppel-like factor 8 ( 359) 564 58.4 3.9e-08
NP_001311033 (OMIM: 300286) Krueppel-like factor 8 ( 364) 564 58.4 4e-08
NP_001273747 (OMIM: 602903) Krueppel-like factor 5 ( 366) 562 58.2 4.4e-08
NP_001721 (OMIM: 602903) Krueppel-like factor 5 is ( 457) 562 58.3 5.1e-08
NP_001291 (OMIM: 176807,602053,613659) Krueppel-li ( 283) 540 56.4 1.2e-07
NP_001257872 (OMIM: 604865) Krueppel-like factor 7 ( 269) 524 55.1 2.8e-07
NP_001257873 (OMIM: 604865) Krueppel-like factor 7 ( 274) 524 55.1 2.9e-07
XP_016875874 (OMIM: 607531) PREDICTED: Krueppel-li ( 352) 526 55.4 3e-07
XP_016860650 (OMIM: 604865) PREDICTED: Krueppel-li ( 302) 524 55.2 3.1e-07
NP_003700 (OMIM: 604865) Krueppel-like factor 7 is ( 302) 524 55.2 3.1e-07
XP_011533213 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 526 55.4 3.2e-07
XP_011533214 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 526 55.4 3.2e-07
XP_016875873 (OMIM: 607531) PREDICTED: Krueppel-li ( 393) 526 55.5 3.3e-07
XP_011533212 (OMIM: 607531) PREDICTED: Krueppel-li ( 400) 526 55.5 3.3e-07
XP_005266308 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 526 55.5 3.3e-07
NP_009180 (OMIM: 607531) Krueppel-like factor 12 [ ( 402) 526 55.5 3.3e-07
XP_011533211 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 526 55.5 3.3e-07
XP_011533209 (OMIM: 607531) PREDICTED: Krueppel-li ( 415) 526 55.5 3.4e-07
XP_011510376 (OMIM: 604865) PREDICTED: Krueppel-li ( 270) 512 54.2 5.5e-07
XP_011510375 (OMIM: 604865) PREDICTED: Krueppel-li ( 272) 512 54.2 5.5e-07
XP_016860651 (OMIM: 604865) PREDICTED: Krueppel-li ( 275) 512 54.2 5.5e-07
XP_006712878 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 512 54.2 5.9e-07
XP_005246983 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 512 54.2 5.9e-07
XP_011510374 (OMIM: 604865) PREDICTED: Krueppel-li ( 303) 512 54.2 5.9e-07
NP_054798 (OMIM: 606465) Krueppel-like factor 15 [ ( 416) 499 53.4 1.4e-06
XP_005247457 (OMIM: 606465) PREDICTED: Krueppel-li ( 416) 499 53.4 1.4e-06
XP_011511045 (OMIM: 606465) PREDICTED: Krueppel-li ( 435) 499 53.4 1.5e-06
XP_011539002 (OMIM: 609602) PREDICTED: Krueppel-li ( 352) 494 52.9 1.7e-06
NP_775755 (OMIM: 609602) Krueppel-like factor 17 [ ( 389) 494 53.0 1.8e-06
NP_114124 (OMIM: 606139) Krueppel-like factor 16 [ ( 252) 458 49.9 9.6e-06
NP_057079 (OMIM: 605328,612001) Krueppel-like fact ( 288) 454 49.7 1.3e-05
NP_001027453 (OMIM: 601878) Krueppel-like factor 1 ( 469) 450 49.6 2.2e-05
NP_005646 (OMIM: 601878) Krueppel-like factor 10 i ( 480) 450 49.6 2.2e-05
NP_001171189 (OMIM: 603301,610508) Krueppel-like f ( 495) 448 49.5 2.5e-05
NP_001171187 (OMIM: 603301,610508) Krueppel-like f ( 495) 448 49.5 2.5e-05
NP_003588 (OMIM: 603301,610508) Krueppel-like fact ( 512) 448 49.5 2.6e-05
NP_001003845 (OMIM: 609391) transcription factor S ( 398) 442 48.9 3.1e-05
>>NP_004226 (OMIM: 602253) Krueppel-like factor 4 isofor (479 aa)
initn: 3406 init1: 3406 opt: 3406 Z-score: 1462.6 bits: 280.0 E(85289): 9.9e-75
Smith-Waterman score: 3406; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479)
10 20 30 40 50 60
pF1KB4 MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 RPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 AATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 AAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PPLHYQELMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PPLHYQELMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTH
370 380 390 400 410 420
430 440 450 460 470
pF1KB4 TGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
430 440 450 460 470
>>NP_001300981 (OMIM: 602253) Krueppel-like factor 4 iso (513 aa)
initn: 2657 init1: 2542 opt: 2670 Z-score: 1152.3 bits: 222.7 E(85289): 1.9e-57
Smith-Waterman score: 3310; 93.3% identity (93.3% similar) in 511 aa overlap (1-477:1-511)
10 20 30 40 50 60
pF1KB4 MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRQAGAPNNRWREELSHMKRLPPVLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 RPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPYDLAAATVATDLESGGAGAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 AATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVSSSASASSSSSPSSSGPASAPSTCSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 AAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAHDFPLGRQLPSRTTPTLGLEEVLSSRDCHPALPLPPGFHPHPGPNYPSFLPDQMQPQV
310 320 330 340 350 360
370 380
pF1KB4 PPLHYQ----------------------------------ELMPPGSCMPEEPKPKRGRR
:::::: ::::::::::::::::::::
NP_001 PPLHYQGQSRGFVARAGEPCVCWPHFGTHGMMLTPPSSPLELMPPGSCMPEEPKPKRGRR
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB4 SWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRH
430 440 450 460 470 480
450 460 470
pF1KB4 YRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
:::::::::::::::::::::::::::::::
NP_001 YRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
490 500 510
>>NP_057354 (OMIM: 602016) Krueppel-like factor 2 [Homo (355 aa)
initn: 866 init1: 729 opt: 823 Z-score: 376.1 bits: 78.5 E(85289): 3.3e-14
Smith-Waterman score: 892; 44.7% identity (58.7% similar) in 380 aa overlap (118-478:5-354)
90 100 110 120 130 140
pF1KB4 LAPLPRRETEEFNDLLDLDFILSNSLTHPPESVAATVSSSASASSSSSPSSSGPASAPST
: . . :. :: . . : . : .
NP_057 MALSEPILPSFSTFASPCRERGLQERWPRAEPES
10 20 30
150 160 170 180 190 200
pF1KB4 CSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPPPTAP-FNLADIND----VSPSGGFVAE
. . . : .. : : : . : ::: : : . . .:.::.:.:
NP_057 GGTDDDLNSVLDFILSMGLDGLGAEAAPEPPPPPPPPAFYYPEPGAPPPYSAPAGGLVSE
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB4 LLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGSHPVV
::::::: : : .: :.:. :. :: .... ::.
NP_057 LLRPELD---------APLGPALHGRFL----LAPPGR------LVKAEPPEADGGGGYG
100 110 120 130
270 280 290 300 310
pF1KB4 VAPYNGGPPRTCPKIKQEAV----SSCTHLGAGPPLSNGHRPAAHDFP-LGRQLPSRTTP
:: :: .:.:.. .:: . :: .:. : : : :. . :.: :
NP_057 CAPGLTRGPRG---LKREGAPGPAASCMR---GP---GGRPPPPPDTPPLSPDGPARL-P
140 150 160 170 180
320 330 340 350 360
pF1KB4 TLGLEEVLSSRDCHPALPLP-PGFHPHPGPNYPSF-LPDQMQPQV------PPLHYQELM
. : . . :.. : ::.: : : :.: : :. . :: :
NP_057 APGPRASFPPPFGGPGFGAPGPGLHYAP-PAPPAFGLFDDAAAAAAALGLAPPAARGLLT
190 200 210 220 230 240
370 380 390 400 410 420
pF1KB4 PPGSCMPE-EPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHC
::.: . : :::::::::::::::::::.:::::::::::::::::::::::::::::
NP_057 PPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHC
250 260 270 280 290 300
430 440 450 460 470
pF1KB4 DWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
.:::::::::::::::::::::::::::::. ::::::::::::::::::
NP_057 NWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM
310 320 330 340 350
>>XP_011525944 (OMIM: 111150,600599,613566,613673) PREDI (324 aa)
initn: 810 init1: 633 opt: 684 Z-score: 318.0 bits: 67.7 E(85289): 5.6e-11
Smith-Waterman score: 687; 47.7% identity (61.5% similar) in 262 aa overlap (239-479:76-324)
210 220 230 240 250 260
pF1KB4 DPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGS---HPVVVAP
:. :.:.... :: : : .:.. :
XP_011 GPEPGGAPQTCALAPSEASGAQYPPPPETLGAYAGGPGLVAGLLGSEDHSGWVRPALRAR
50 60 70 80 90 100
270 280 290 300 310
pF1KB4 YNG---GP---PRTCPKIKQEAVSSCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTL
:: : :. : :.. .. : : :.:. : . : ..:. .
XP_011 APDAFVGPALAPAPAPEPKALALQP-VYPGPGAGSSGGYFPRT-----GLSVPAASGAPY
110 120 130 140 150
320 330 340 350 360
pF1KB4 GLEEVLSSRDCHPAL-PLPP---------GFH-PHPGP-NYPSFLPDQMQPQVPPLHYQE
:: ::. .::. : : :.. : ::: . :::: :
XP_011 GL---LSG---YPAMYPAPQYQGHFQLFRGLQGPAPGPATSPSFLSCLGPGTVGTGLGGT
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB4 LMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYH
:: . : ::::::: ::: :.::: . ::::.::::::::::::::::::::
XP_011 AEDPG-VIAETAPSKRGRRSWARKRQAAHTCAHPGCGKSYTKSSHLKAHLRTHTGEKPYA
220 230 240 250 260 270
430 440 450 460 470
pF1KB4 CDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
: :.::::.::::::::::::::::.:::.:: : ::::::::::::::::.
XP_011 CTWEGCGWRFARSDELTRHYRKHTGQRPFRCQLCPRAFSRSDHLALHMKRHL
280 290 300 310 320
>>NP_006554 (OMIM: 111150,600599,613566,613673) Krueppel (362 aa)
initn: 815 init1: 633 opt: 684 Z-score: 317.5 bits: 67.7 E(85289): 6.1e-11
Smith-Waterman score: 687; 47.7% identity (61.5% similar) in 262 aa overlap (239-479:114-362)
210 220 230 240 250 260
pF1KB4 DPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGS---HPVVVAP
:. :.:.... :: : : .:.. :
NP_006 GPEPGGAPQTCALAPSEASGAQYPPPPETLGAYAGGPGLVAGLLGSEDHSGWVRPALRAR
90 100 110 120 130 140
270 280 290 300 310
pF1KB4 YNG---GP---PRTCPKIKQEAVSSCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTL
:: : :. : :.. .. : : :.:. : . : ..:. .
NP_006 APDAFVGPALAPAPAPEPKALALQP-VYPGPGAGSSGGYFPRT-----GLSVPAASGAPY
150 160 170 180 190
320 330 340 350 360
pF1KB4 GLEEVLSSRDCHPAL-PLPP---------GFH-PHPGP-NYPSFLPDQMQPQVPPLHYQE
:: ::. .::. : : :.. : ::: . :::: :
NP_006 GL---LSG---YPAMYPAPQYQGHFQLFRGLQGPAPGPATSPSFLSCLGPGTVGTGLGGT
200 210 220 230 240 250
370 380 390 400 410 420
pF1KB4 LMPPGSCMPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYH
:: . : ::::::: ::: :.::: . ::::.::::::::::::::::::::
NP_006 AEDPG-VIAETAPSKRGRRSWARKRQAAHTCAHPGCGKSYTKSSHLKAHLRTHTGEKPYA
260 270 280 290 300 310
430 440 450 460 470
pF1KB4 CDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
: :.::::.::::::::::::::::.:::.:: : ::::::::::::::::.
NP_006 CTWEGCGWRFARSDELTRHYRKHTGQRPFRCQLCPRAFSRSDHLALHMKRHL
320 330 340 350 360
>>XP_016863768 (OMIM: 609392) PREDICTED: Krueppel-like f (320 aa)
initn: 568 init1: 525 opt: 582 Z-score: 275.1 bits: 59.7 E(85289): 1.4e-08
Smith-Waterman score: 591; 38.7% identity (58.6% similar) in 292 aa overlap (207-478:33-317)
180 190 200 210 220 230
pF1KB4 SAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIP-PQQPQPPGGGLMG---KFVLK
...:: . .. .::..: :: .
XP_016 SMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQMEPVDLTVNKRSSPPSAGNSPSSLKFPSS
10 20 30 40 50 60
240 250 260 270 280 290
pF1KB4 ASLSAPGSEY--GSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGA
..:: . .:: . . : :: : .: : : . :: ...... : : .
XP_016 HRRASPGLSMPSSSPPIKKYSPPSP-GVQPFGV-PLSM-PPVMAAALSRHGIRSPGILPV
70 80 90 100 110
300 310 320 330
pF1KB4 GPPLSNGHRPAAHDFPLGRQLPSRTTPTLGLEEVLSSRDC-------HPA----LPLPPG
:. .:. . : : .. . .:. :: . .: . . ::
XP_016 IQPVVV--QPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEPG
120 130 140 150 160 170
340 350 360 370 380 390
pF1KB4 FHPHPGPNYPSFL-PDQMQPQVPPLHY-QELMPPGSCMP-EEPKPKRGRRSWPRKRTATH
..:. :: . : :. :: :: : .: ..: : .. . ..: :
XP_016 IEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRI--H
180 190 200 210 220 230
400 410 420 430 440 450
pF1KB4 TCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPF
::: ::.:.:::::::::: :::::::::.: :.:: ::::::::::::.::::: .::
XP_016 RCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPF
240 250 260 270 280 290
460 470
pF1KB4 QCQKCDRAFSRSDHLALHMKRHF
:: :::.:::::::::: :::
XP_016 QCPDCDRSFSRSDHLALHRKRHMLV
300 310 320
>>NP_057615 (OMIM: 609392) Krueppel-like factor 3 [Homo (345 aa)
initn: 547 init1: 525 opt: 582 Z-score: 274.7 bits: 59.8 E(85289): 1.5e-08
Smith-Waterman score: 591; 38.7% identity (58.6% similar) in 292 aa overlap (207-478:58-342)
180 190 200 210 220 230
pF1KB4 SAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIP-PQQPQPPGGGLMG---KFVLK
...:: . .. .::..: :: .
NP_057 SMKPNKYGVIYSTPLPEKFFQTPEGLSHGIQMEPVDLTVNKRSSPPSAGNSPSSLKFPSS
30 40 50 60 70 80
240 250 260 270 280 290
pF1KB4 ASLSAPGSEY--GSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVSSCTHLGA
..:: . .:: . . : :: : .: : : . :: ...... : : .
NP_057 HRRASPGLSMPSSSPPIKKYSPPSP-GVQPFGV-PLSM-PPVMAAALSRHGIRSPGILPV
90 100 110 120 130 140
300 310 320 330
pF1KB4 GPPLSNGHRPAAHDFPLGRQLPSRTTPTLGLEEVLSSRDC-------HPA----LPLPPG
:. .:. . : : .. . .:. :: . .: . . ::
NP_057 IQPVVV--QPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEKPISQKKIKIEPG
150 160 170 180 190 200
340 350 360 370 380 390
pF1KB4 FHPHPGPNYPSFL-PDQMQPQVPPLHY-QELMPPGSCMP-EEPKPKRGRRSWPRKRTATH
..:. :: . : :. :: :: : .: ..: : .. . ..: :
NP_057 IEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKRRI--H
210 220 230 240 250 260
400 410 420 430 440 450
pF1KB4 TCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPF
::: ::.:.:::::::::: :::::::::.: :.:: ::::::::::::.::::: .::
NP_057 RCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPF
270 280 290 300 310 320
460 470
pF1KB4 QCQKCDRAFSRSDHLALHMKRHF
:: :::.:::::::::: :::
NP_057 QCPDCDRSFSRSDHLALHRKRHMLV
330 340
>>XP_011529061 (OMIM: 300286) PREDICTED: Krueppel-like f (354 aa)
initn: 535 init1: 513 opt: 572 Z-score: 270.4 bits: 59.0 E(85289): 2.5e-08
Smith-Waterman score: 598; 35.1% identity (55.6% similar) in 365 aa overlap (138-478:9-351)
110 120 130 140 150 160
pF1KB4 ILSNSLTHPPESVAATVSSSASASSSSSPSSSGPASAPS--TCSFTYPIRAGNDPGVA--
::: .:. : : : .: . : .
XP_011 MSLPEDGMSSGHFRSPQLVTWSVTASVRNRDPPEIEYR
10 20 30
170 180 190 200 210 220
pF1KB4 PGGTGGGLLYGRESAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGG
. :. :: .: : : . ::. : ..... :...:: . ..:. :
XP_011 SNMTSPTLL----DANPMENPALFNDIKIEPPEELLASDFSLPQVEPVDLSFHKPKAP--
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB4 GLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVS
:. .:.: . : . .::... :: .. : : . . : : ...
XP_011 -LQPASMLQAPIRPPKPQ-SSPQTLVVSTSTSDMSTSANI------PTVLTPG---SVLT
100 110 120 130 140
290 300 310 320 330
pF1KB4 SCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTL--GLEEVLSS--RDCHPA---LPL
: :. : : . ..: ... .: :.. .: : .. : :: .::
XP_011 SSQSTGSQQILHVIHTIPSVSLP-NKMGGLKTIPVVVQSLPMVYTTLPADGGPAAITVPL
150 160 170 180 190 200
340 350 360 370 380
pF1KB4 PPGFHPHPGPNYPSFL--PDQMQP-QVPPLHYQELMPPGSC-------MPEEPKPK---R
: : : : : .:.: ..: . . :: . .:: .
XP_011 IGG----DGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQEPAAMAQMQ
210 220 230 240 250
390 400 410 420 430 440
pF1KB4 GRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDEL
:..: :: : ::.:::.:.:::::::::: : :::::::.: ::::.:::::::::
XP_011 GEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDEL
260 270 280 290 300 310
450 460 470
pF1KB4 TRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
:::.::::: .::.: :.:.:::::::.:: .::
XP_011 TRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM
320 330 340 350
>>XP_016884739 (OMIM: 300286) PREDICTED: Krueppel-like f (354 aa)
initn: 535 init1: 513 opt: 572 Z-score: 270.4 bits: 59.0 E(85289): 2.5e-08
Smith-Waterman score: 598; 35.1% identity (55.6% similar) in 365 aa overlap (138-478:9-351)
110 120 130 140 150 160
pF1KB4 ILSNSLTHPPESVAATVSSSASASSSSSPSSSGPASAPS--TCSFTYPIRAGNDPGVA--
::: .:. : : : .: . : .
XP_016 MSLPEDGMSSGHFRSPQLVTWSVTASVRNRDPPEIEYR
10 20 30
170 180 190 200 210 220
pF1KB4 PGGTGGGLLYGRESAPPPTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGG
. :. :: .: : : . ::. : ..... :...:: . ..:. :
XP_016 SNMTSPTLL----DANPMENPALFNDIKIEPPEELLASDFSLPQVEPVDLSFHKPKAP--
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB4 GLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGSHPVVVAPYNGGPPRTCPKIKQEAVS
:. .:.: . : . .::... :: .. : : . . : : ...
XP_016 -LQPASMLQAPIRPPKPQ-SSPQTLVVSTSTSDMSTSANI------PTVLTPG---SVLT
100 110 120 130 140
290 300 310 320 330
pF1KB4 SCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTL--GLEEVLSS--RDCHPA---LPL
: :. : : . ..: ... .: :.. .: : .. : :: .::
XP_016 SSQSTGSQQILHVIHTIPSVSLP-NKMGGLKTIPVVVQSLPMVYTTLPADGGPAAITVPL
150 160 170 180 190 200
340 350 360 370 380
pF1KB4 PPGFHPHPGPNYPSFL--PDQMQP-QVPPLHYQELMPPGSC-------MPEEPKPK---R
: : : : : .:.: ..: . . :: . .:: .
XP_016 IGG----DGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQEPAAMAQMQ
210 220 230 240 250
390 400 410 420 430 440
pF1KB4 GRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDEL
:..: :: : ::.:::.:.:::::::::: : :::::::.: ::::.:::::::::
XP_016 GEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDEL
260 270 280 290 300 310
450 460 470
pF1KB4 TRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
:::.::::: .::.: :.:.:::::::.:: .::
XP_016 TRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM
320 330 340 350
>>NP_001311034 (OMIM: 300286) Krueppel-like factor 8 iso (356 aa)
initn: 535 init1: 513 opt: 564 Z-score: 267.0 bits: 58.4 E(85289): 3.9e-08
Smith-Waterman score: 590; 36.1% identity (57.0% similar) in 321 aa overlap (178-478:51-353)
150 160 170 180 190 200
pF1KB4 CSFTYPIRAGNDPGVAPGGTGGGLLYGRESAPPPTAPFNLADINDVSPSGGFVAELLRPE
: : : . ::. : ..... :.
NP_001 VFKQVTASVRNRDPPEIEYRSNMTSPTLLDANPMENPALFNDIKIEPPEELLASDFSLPQ
30 40 50 60 70 80
210 220 230 240 250 260
pF1KB4 LDPVYIPPQQPQPPGGGLMGKFVLKASLSAPGSEYGSPSVISVSKGSPDGSHPVVVAPYN
..:: . ..:. : :. .:.: . : . .::... :: .. : : . .
NP_001 VEPVDLSFHKPKAP---LQPASMLQAPIRPPKPQ-SSPQTLVVSTSTSDMSTSANI----
90 100 110 120 130
270 280 290 300 310 320
pF1KB4 GGPPRTCPKIKQEAVSSCTHLGAGPPLSNGHRPAAHDFPLGRQLPSRTTPTL--GLEEVL
: : ...: :. : : . ..: ... .: :.. .: :
NP_001 --PTVLTPG---SVLTSSQSTGSQQILHVIHTIPSVSLP-NKMGGLKTIPVVVQSLPMVY
140 150 160 170 180
330 340 350 360 370
pF1KB4 SS--RDCHPA---LPLPPGFHPHPGPNYPSFL--PDQMQP-QVPPLHYQELMPPGSC---
.. : :: .:: : : : : : .:.: ..: . . ::
NP_001 TTLPADGGPAAITVPLIGG----DGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQ
190 200 210 220 230 240
380 390 400 410 420
pF1KB4 ----MPEEPKPK---RGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYH
. .:: .:..: :: : ::.:::.:.:::::::::: : :::::::.
NP_001 SLQGLQQEPAAMAQMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYK
250 260 270 280 290 300
430 440 450 460 470
pF1KB4 CDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
: ::::.::::::::::::.::::: .::.: :.:.:::::::.:: .::
NP_001 CTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM
310 320 330 340 350
479 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:36:43 2016 done: Thu Nov 3 15:36:45 2016
Total Scan time: 12.820 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]