Result of FASTA (omim) for pF1KB4976
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4976, 418 aa
  1>>>pF1KB4976 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4552+/-0.000303; mu= 17.3673+/- 0.019
 mean_var=78.2214+/-15.661, 0's: 0 Z-trim(117.4): 28  B-trim: 49 in 3/54
 Lambda= 0.145014
 statistics sampled from 29281 (29310) to 29281 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.344), width:  16
 Scan time:  8.540

The best scores are:                                      opt bits E(85289)
NP_004032 (OMIM: 107940) beta-arrestin-1 isoform A ( 418) 2776 590.0 3.6e-168
XP_011543336 (OMIM: 107940) PREDICTED: beta-arrest ( 449) 2736 581.7 1.3e-165
NP_064647 (OMIM: 107940) beta-arrestin-1 isoform B ( 410) 2704 575.0 1.2e-163
XP_011543337 (OMIM: 107940) PREDICTED: beta-arrest ( 441) 2664 566.6 4.2e-161
XP_016873241 (OMIM: 107940) PREDICTED: beta-arrest ( 442) 2532 539.0 8.7e-153
XP_016873239 (OMIM: 107940) PREDICTED: beta-arrest ( 473) 2492 530.7  3e-150
XP_016873242 (OMIM: 107940) PREDICTED: beta-arrest ( 437) 2483 528.8 1.1e-149
XP_016873243 (OMIM: 107940) PREDICTED: beta-arrest ( 434) 2460 523.9 2.9e-148
XP_016873240 (OMIM: 107940) PREDICTED: beta-arrest ( 465) 2420 515.6  1e-145
NP_004304 (OMIM: 107941) beta-arrestin-2 isoform 1 ( 409) 2150 459.1 9.4e-129
XP_011522160 (OMIM: 107941) PREDICTED: beta-arrest ( 440) 2126 454.1 3.2e-127
NP_001244259 (OMIM: 107941) beta-arrestin-2 isofor ( 421) 2005 428.7 1.3e-119
NP_945355 (OMIM: 107941) beta-arrestin-2 isoform 2 ( 394) 1865 399.4 8.1e-111
NP_001244260 (OMIM: 107941) beta-arrestin-2 isofor ( 406) 1720 369.1 1.1e-101
NP_004303 (OMIM: 301770) arrestin-C [Homo sapiens] ( 388) 1545 332.5 1.1e-90
NP_001244257 (OMIM: 107941) beta-arrestin-2 isofor ( 430) 1514 326.0 1.1e-88
NP_001244258 (OMIM: 107941) beta-arrestin-2 isofor ( 330) 1479 318.6 1.4e-86
NP_000532 (OMIM: 181031,258100,613758) S-arrestin  ( 405) 1475 317.8   3e-86
XP_016860131 (OMIM: 181031,258100,613758) PREDICTE ( 369) 1473 317.4 3.7e-86
XP_016860130 (OMIM: 181031,258100,613758) PREDICTE ( 373) 1473 317.4 3.8e-86
XP_016885007 (OMIM: 301770) PREDICTED: arrestin-C  ( 403) 1374 296.7 6.9e-80
NP_001316993 (OMIM: 107941) beta-arrestin-2 isofor ( 217) 1064 231.7 1.4e-60
XP_016860132 (OMIM: 181031,258100,613758) PREDICTE ( 273) 1047 228.2   2e-59
XP_011509895 (OMIM: 181031,258100,613758) PREDICTE ( 305) 1025 223.6 5.3e-58
XP_011509896 (OMIM: 181031,258100,613758) PREDICTE ( 281) 1017 221.9 1.6e-57
XP_011509898 (OMIM: 181031,258100,613758) PREDICTE ( 271)  973 212.7   9e-55
XP_016880134 (OMIM: 107941) PREDICTED: beta-arrest ( 229)  919 201.4   2e-51


>>NP_004032 (OMIM: 107940) beta-arrestin-1 isoform A [Ho  (418 aa)
 initn: 2776 init1: 2776 opt: 2776  Z-score: 3140.2  bits: 590.0 E(85289): 3.6e-168
Smith-Waterman score: 2776; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)

               10        20        30        40        50        60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
              310       320       330       340       350       360

              370       380       390       400       410        
pF1KB4 PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
              370       380       390       400       410        

>>XP_011543336 (OMIM: 107940) PREDICTED: beta-arrestin-1  (449 aa)
 initn: 2736 init1: 2736 opt: 2736  Z-score: 3094.5  bits: 581.7 E(85289): 1.3e-165
Smith-Waterman score: 2736; 99.8% identity (100.0% similar) in 413 aa overlap (6-418:37-449)

                                        10        20        30     
pF1KB4                          MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVD
                                     .:::::::::::::::::::::::::::::
XP_011 RERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVDHIDLVD
         10        20        30        40        50        60      

          40        50        60        70        80        90     
pF1KB4 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
         70        80        90       100       110       120      

         100       110       120       130       140       150     
pF1KB4 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
        130       140       150       160       170       180      

         160       170       180       190       200       210     
pF1KB4 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
        190       200       210       220       230       240      

         220       230       240       250       260       270     
pF1KB4 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
        250       260       270       280       290       300      

         280       290       300       310       320       330     
pF1KB4 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
        310       320       330       340       350       360      

         340       350       360       370       380       390     
pF1KB4 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQR
        370       380       390       400       410       420      

         400       410        
pF1KB4 LKGMKDDKEEEEDGTGSPQLNNR
       :::::::::::::::::::::::
XP_011 LKGMKDDKEEEEDGTGSPQLNNR
        430       440         

>>NP_064647 (OMIM: 107940) beta-arrestin-1 isoform B [Ho  (410 aa)
 initn: 2716 init1: 2204 opt: 2704  Z-score: 3058.9  bits: 575.0 E(85289): 1.2e-163
Smith-Waterman score: 2704; 98.1% identity (98.1% similar) in 418 aa overlap (1-418:1-410)

               10        20        30        40        50        60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
       :::::::::::::::::::::::::::::::::        :::::::::::::::::::
NP_064 ASSTLLREGANREILGIIVSYKVKVKLVVSRGG--------DVAVELPFTLMHPKPKEEP
              310       320       330               340       350  

              370       380       390       400       410        
pF1KB4 PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
            360       370       380       390       400       410

>>XP_011543337 (OMIM: 107940) PREDICTED: beta-arrestin-1  (441 aa)
 initn: 2676 init1: 2164 opt: 2664  Z-score: 3013.2  bits: 566.6 E(85289): 4.2e-161
Smith-Waterman score: 2664; 97.8% identity (98.1% similar) in 413 aa overlap (6-418:37-441)

                                        10        20        30     
pF1KB4                          MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVD
                                     .:::::::::::::::::::::::::::::
XP_011 RERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVDHIDLVD
         10        20        30        40        50        60      

          40        50        60        70        80        90     
pF1KB4 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
         70        80        90       100       110       120      

         100       110       120       130       140       150     
pF1KB4 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
        130       140       150       160       170       180      

         160       170       180       190       200       210     
pF1KB4 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
        190       200       210       220       230       240      

         220       230       240       250       260       270     
pF1KB4 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
        250       260       270       280       290       300      

         280       290       300       310       320       330     
pF1KB4 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_011 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGG--
        310       320       330       340       350       360      

         340       350       360       370       380       390     
pF1KB4 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQR
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ------DVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQR
                370       380       390       400       410        

         400       410        
pF1KB4 LKGMKDDKEEEEDGTGSPQLNNR
       :::::::::::::::::::::::
XP_011 LKGMKDDKEEEEDGTGSPQLNNR
      420       430       440 

>>XP_016873241 (OMIM: 107940) PREDICTED: beta-arrestin-1  (442 aa)
 initn: 2532 init1: 2532 opt: 2532  Z-score: 2864.0  bits: 539.0 E(85289): 8.7e-153
Smith-Waterman score: 2718; 94.6% identity (94.6% similar) in 442 aa overlap (1-418:1-442)

               10        20        30        40        50        60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
              310       320       330       340       350       360

              370       380                               390      
pF1KB4 PHREVPENETPVDTNLIELDTN------------------------DDDIVFEDFARQRL
       ::::::::::::::::::::::                        ::::::::::::::
XP_016 PHREVPENETPVDTNLIELDTNQRPSSHRTVARGGGPGPTARTASSDDDIVFEDFARQRL
              370       380       390       400       410       420

        400       410        
pF1KB4 KGMKDDKEEEEDGTGSPQLNNR
       ::::::::::::::::::::::
XP_016 KGMKDDKEEEEDGTGSPQLNNR
              430       440  

>>XP_016873239 (OMIM: 107940) PREDICTED: beta-arrestin-1  (473 aa)
 initn: 2492 init1: 2492 opt: 2492  Z-score: 2818.3  bits: 530.7 E(85289): 3e-150
Smith-Waterman score: 2678; 94.3% identity (94.5% similar) in 437 aa overlap (6-418:37-473)

                                        10        20        30     
pF1KB4                          MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVD
                                     .:::::::::::::::::::::::::::::
XP_016 RERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVDHIDLVD
         10        20        30        40        50        60      

          40        50        60        70        80        90     
pF1KB4 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
         70        80        90       100       110       120      

         100       110       120       130       140       150     
pF1KB4 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
        130       140       150       160       170       180      

         160       170       180       190       200       210     
pF1KB4 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
        190       200       210       220       230       240      

         220       230       240       250       260       270     
pF1KB4 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
        250       260       270       280       290       300      

         280       290       300       310       320       330     
pF1KB4 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
        310       320       330       340       350       360      

         340       350       360       370       380               
pF1KB4 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTN-------------
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_016 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNQRPSSHRTVARGG
        370       380       390       400       410       420      

                       390       400       410        
pF1KB4 -----------DDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
                  ::::::::::::::::::::::::::::::::::::
XP_016 GPGPTARTASSDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
        430       440       450       460       470   

>>XP_016873242 (OMIM: 107940) PREDICTED: beta-arrestin-1  (437 aa)
 initn: 2483 init1: 2483 opt: 2483  Z-score: 2808.7  bits: 528.8 E(85289): 1.1e-149
Smith-Waterman score: 2669; 94.5% identity (94.5% similar) in 435 aa overlap (8-418:3-437)

               10        20        30        40        50        60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016      MGVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
                    10        20        30        40        50     

               70        80        90       100       110       120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
          60        70        80        90       100       110     

              130       140       150       160       170       180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
         120       130       140       150       160       170     

              190       200       210       220       230       240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
         180       190       200       210       220       230     

              250       260       270       280       290       300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
         240       250       260       270       280       290     

              310       320       330       340       350       360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
         300       310       320       330       340       350     

              370       380                               390      
pF1KB4 PHREVPENETPVDTNLIELDTN------------------------DDDIVFEDFARQRL
       ::::::::::::::::::::::                        ::::::::::::::
XP_016 PHREVPENETPVDTNLIELDTNQRPSSHRTVARGGGPGPTARTASSDDDIVFEDFARQRL
         360       370       380       390       400       410     

        400       410        
pF1KB4 KGMKDDKEEEEDGTGSPQLNNR
       ::::::::::::::::::::::
XP_016 KGMKDDKEEEEDGTGSPQLNNR
         420       430       

>>XP_016873243 (OMIM: 107940) PREDICTED: beta-arrestin-1  (434 aa)
 initn: 2472 init1: 2204 opt: 2460  Z-score: 2782.7  bits: 523.9 E(85289): 2.9e-148
Smith-Waterman score: 2646; 92.8% identity (92.8% similar) in 442 aa overlap (1-418:1-434)

               10        20        30        40        50        60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
       :::::::::::::::::::::::::::::::::        :::::::::::::::::::
XP_016 ASSTLLREGANREILGIIVSYKVKVKLVVSRGG--------DVAVELPFTLMHPKPKEEP
              310       320       330               340       350  

              370       380                               390      
pF1KB4 PHREVPENETPVDTNLIELDTN------------------------DDDIVFEDFARQRL
       ::::::::::::::::::::::                        ::::::::::::::
XP_016 PHREVPENETPVDTNLIELDTNQRPSSHRTVARGGGPGPTARTASSDDDIVFEDFARQRL
            360       370       380       390       400       410  

        400       410        
pF1KB4 KGMKDDKEEEEDGTGSPQLNNR
       ::::::::::::::::::::::
XP_016 KGMKDDKEEEEDGTGSPQLNNR
            420       430    

>>XP_016873240 (OMIM: 107940) PREDICTED: beta-arrestin-1  (465 aa)
 initn: 2432 init1: 2164 opt: 2420  Z-score: 2737.0  bits: 515.6 E(85289): 1e-145
Smith-Waterman score: 2606; 92.4% identity (92.7% similar) in 437 aa overlap (6-418:37-465)

                                        10        20        30     
pF1KB4                          MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVD
                                     .:::::::::::::::::::::::::::::
XP_016 RERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVDHIDLVD
         10        20        30        40        50        60      

          40        50        60        70        80        90     
pF1KB4 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
         70        80        90       100       110       120      

         100       110       120       130       140       150     
pF1KB4 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
        130       140       150       160       170       180      

         160       170       180       190       200       210     
pF1KB4 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
        190       200       210       220       230       240      

         220       230       240       250       260       270     
pF1KB4 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
        250       260       270       280       290       300      

         280       290       300       310       320       330     
pF1KB4 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_016 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGG--
        310       320       330       340       350       360      

         340       350       360       370       380               
pF1KB4 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTN-------------
             :::::::::::::::::::::::::::::::::::::::::             
XP_016 ------DVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNQRPSSHRTVARGG
                370       380       390       400       410        

                       390       400       410        
pF1KB4 -----------DDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
                  ::::::::::::::::::::::::::::::::::::
XP_016 GPGPTARTASSDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
      420       430       440       450       460     

>>NP_004304 (OMIM: 107941) beta-arrestin-2 isoform 1 [Ho  (409 aa)
 initn: 2079 init1: 1870 opt: 2150  Z-score: 2432.5  bits: 459.1 E(85289): 9.4e-129
Smith-Waterman score: 2150; 76.4% identity (91.6% similar) in 415 aa overlap (1-407:1-407)

                10        20        30        40        50         
pF1KB4 MGDK-GTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTC
       ::.: :::::::.::: ::::::::::::::.: ::::::::::::.:::.:.:.:::::
NP_004 MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTC
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB4 AFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEI
       ::::::::::::::.::::::.:. :.:::.:.  .: ::::.::..:::.::.:: : :
NP_004 AFRYGREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTI
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB4 PPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPG
       : ::::::::::::::::::::::.:..::::..:::: ::::::::::::::.:::.::
NP_004 PQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPG
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB4 PQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYA
       :::.:::::.:::::. ::::::::::.::::::..::::::::..:::::::.::::::
NP_004 PQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYA
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB4 DICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTN
       :::::.:::::::::. : :: :.::::::::::.::.:..:::::::::::::::::::
NP_004 DICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTN
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB4 LASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEE
       :::::...::::.:.:::.:::.:::::::::::        ::.:::::.::::::...
NP_004 LASSTIVKEGANKEVLGILVSYRVKVKLVVSRGG--------DVSVELPFVLMHPKPHDH
              310       320       330               340       350  

      360          370       380          390       400       410  
pF1KB4 -P---PHREVPENETPVDTNLIELDTN---DDDIVFEDFARQRLKGMKDDKEEEEDGTGS
        :   :.  .::...::::::::.:::   ::::::::::: ::::::::  ...     
NP_004 IPLPRPQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC   
            360       370       380       390       400            

             
pF1KB4 PQLNNR




418 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:19:24 2016 done: Fri Nov  4 03:19:25 2016
 Total Scan time:  8.540 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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