FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4977, 400 aa 1>>>pF1KB4977 400 - 400 aa - 400 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0609+/-0.000985; mu= 13.7986+/- 0.059 mean_var=103.7718+/-21.298, 0's: 0 Z-trim(106.9): 100 B-trim: 61 in 2/50 Lambda= 0.125903 statistics sampled from 9144 (9249) to 9144 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.284), width: 16 Scan time: 2.060 The best scores are: opt bits E(32554) CCDS8273.1 EED gene_id:8726|Hs108|chr11 ( 441) 2783 516.4 2.1e-146 CCDS76463.1 EED gene_id:8726|Hs108|chr11 ( 466) 2224 414.9 8e-116 CCDS81612.1 EED gene_id:8726|Hs108|chr11 ( 361) 1655 311.4 8.5e-85 >>CCDS8273.1 EED gene_id:8726|Hs108|chr11 (441 aa) initn: 2783 init1: 2783 opt: 2783 Z-score: 2742.0 bits: 516.4 E(32554): 2.1e-146 Smith-Waterman score: 2783; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400) 10 20 30 40 50 60 pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ 310 320 330 340 350 360 370 380 390 400 pF1KB4 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAK :::::::::::::::::::::::::::::::::::::::: CCDS82 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSR 370 380 390 400 410 420 CCDS82 DSSILIAVCDDASIWRWDRLR 430 440 >>CCDS76463.1 EED gene_id:8726|Hs108|chr11 (466 aa) initn: 2223 init1: 2223 opt: 2224 Z-score: 2192.9 bits: 414.9 E(32554): 8e-116 Smith-Waterman score: 2723; 94.1% identity (94.1% similar) in 425 aa overlap (1-400:1-425) 10 20 30 40 50 60 pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS 250 260 270 280 290 300 310 320 330 pF1KB4 TRDIHRNYVDCVRWLGDLILSKS-------------------------CENAIVCWKPGK ::::::::::::::::::::::: :::::::::::: CCDS76 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED 370 380 390 400 410 420 400 pF1KB4 PHKAK ::::: CCDS76 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR 430 440 450 460 >>CCDS81612.1 EED gene_id:8726|Hs108|chr11 (361 aa) initn: 1655 init1: 1655 opt: 1655 Z-score: 1635.9 bits: 311.4 E(32554): 8.5e-85 Smith-Waterman score: 2050; 80.0% identity (80.0% similar) in 400 aa overlap (1-400:1-320) 10 20 30 40 50 60 pF1KB4 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS :: CCDS81 SA---------------------------------------------------------- 310 320 330 340 350 360 pF1KB4 TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ :::::::::::::::::::::::::::::::::::::: CCDS81 ----------------------SCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ 250 260 270 280 370 380 390 400 pF1KB4 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAK :::::::::::::::::::::::::::::::::::::::: CCDS81 CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSR 290 300 310 320 330 340 CCDS81 DSSILIAVCDDASIWRWDRLR 350 360 400 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:19:57 2016 done: Fri Nov 4 03:19:57 2016 Total Scan time: 2.060 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]