FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4982, 801 aa 1>>>pF1KB4982 801 - 801 aa - 801 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3225+/-0.000473; mu= 14.3523+/- 0.030 mean_var=326.2447+/-70.453, 0's: 0 Z-trim(119.1): 1789 B-trim: 1269 in 1/54 Lambda= 0.071007 statistics sampled from 30476 (32699) to 30476 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.383), width: 16 Scan time: 12.640 The best scores are: opt bits E(85289) NP_036538 (OMIM: 605780) PR domain zinc finger pro ( 801) 5478 576.2 1.9e-163 XP_005268650 (OMIM: 605780) PREDICTED: PR domain z ( 808) 5454 573.7 1.1e-162 NP_078780 (OMIM: 611781) PR domain zinc finger pro ( 571) 576 73.8 2.4e-12 XP_016873758 (OMIM: 605015) PREDICTED: zinc finger ( 592) 565 72.7 5.3e-12 XP_005253186 (OMIM: 605015) PREDICTED: zinc finger ( 592) 565 72.7 5.3e-12 XP_006718372 (OMIM: 605015) PREDICTED: zinc finger ( 592) 565 72.7 5.3e-12 XP_011518659 (OMIM: 605015) PREDICTED: zinc finger ( 592) 565 72.7 5.3e-12 XP_005253185 (OMIM: 605015) PREDICTED: zinc finger ( 606) 565 72.7 5.4e-12 XP_006718371 (OMIM: 605015) PREDICTED: zinc finger ( 606) 565 72.7 5.4e-12 NP_037381 (OMIM: 605015) zinc finger protein 214 [ ( 606) 565 72.7 5.4e-12 XP_011518657 (OMIM: 605015) PREDICTED: zinc finger ( 617) 565 72.7 5.4e-12 XP_011515874 (OMIM: 611781) PREDICTED: PR domain z ( 316) 548 70.5 1.3e-11 XP_016882933 (OMIM: 616841) PREDICTED: zinc finger ( 469) 550 71.0 1.4e-11 NP_001008801 (OMIM: 616841) zinc finger protein 46 ( 522) 550 71.1 1.4e-11 XP_016882932 (OMIM: 616841) PREDICTED: zinc finger ( 541) 550 71.1 1.5e-11 XP_016882723 (OMIM: 603899) PREDICTED: zinc finger ( 518) 548 70.9 1.7e-11 NP_001243102 (OMIM: 603899) zinc finger protein 85 ( 531) 548 70.9 1.7e-11 XP_011526566 (OMIM: 603899) PREDICTED: zinc finger ( 536) 548 70.9 1.7e-11 NP_003420 (OMIM: 603899) zinc finger protein 85 is ( 595) 548 71.0 1.8e-11 NP_001243100 (OMIM: 603899) zinc finger protein 85 ( 625) 548 71.0 1.8e-11 XP_011526565 (OMIM: 603899) PREDICTED: zinc finger ( 640) 548 71.0 1.8e-11 NP_001309067 (OMIM: 600398) zinc finger protein 16 ( 782) 548 71.1 2e-11 NP_001309066 (OMIM: 600398) zinc finger protein 16 ( 782) 548 71.1 2e-11 NP_001309068 (OMIM: 600398) zinc finger protein 16 ( 782) 548 71.1 2e-11 NP_001309062 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 NP_001309063 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 NP_001309065 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 NP_001309058 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 NP_001309064 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 NP_001309060 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 NP_942596 (OMIM: 600398) zinc finger protein 160 i ( 818) 548 71.2 2.1e-11 NP_001309057 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 XP_016882935 (OMIM: 600398) PREDICTED: zinc finger ( 818) 548 71.2 2.1e-11 NP_001309059 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 NP_150630 (OMIM: 600398) zinc finger protein 160 i ( 818) 548 71.2 2.1e-11 NP_001096073 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 NP_001309061 (OMIM: 600398) zinc finger protein 16 ( 818) 548 71.2 2.1e-11 XP_016882934 (OMIM: 600398) PREDICTED: zinc finger ( 837) 548 71.2 2.1e-11 NP_775802 (OMIM: 603982) zinc finger protein 100 [ ( 542) 543 70.4 2.4e-11 XP_016881641 (OMIM: 604750) PREDICTED: zinc finger ( 502) 539 69.9 3.1e-11 XP_016881642 (OMIM: 604750) PREDICTED: zinc finger ( 502) 539 69.9 3.1e-11 XP_011542202 (OMIM: 300498,314998) PREDICTED: zinc ( 661) 540 70.2 3.3e-11 XP_005272657 (OMIM: 300498,314998) PREDICTED: zinc ( 661) 540 70.2 3.3e-11 XP_016884976 (OMIM: 300498,314998) PREDICTED: zinc ( 661) 540 70.2 3.3e-11 XP_016884975 (OMIM: 300498,314998) PREDICTED: zinc ( 661) 540 70.2 3.3e-11 XP_011542201 (OMIM: 300498,314998) PREDICTED: zinc ( 661) 540 70.2 3.3e-11 NP_009068 (OMIM: 300498,314998) zinc finger protei ( 661) 540 70.2 3.3e-11 NP_998763 (OMIM: 616847) zinc finger protein 543 [ ( 600) 539 70.0 3.4e-11 XP_016881882 (OMIM: 606427) PREDICTED: zinc finger ( 509) 537 69.7 3.6e-11 XP_016881888 (OMIM: 606427) PREDICTED: zinc finger ( 509) 537 69.7 3.6e-11 >>NP_036538 (OMIM: 605780) PR domain zinc finger protein (801 aa) initn: 5478 init1: 5478 opt: 5478 Z-score: 3055.3 bits: 576.2 E(85289): 1.9e-163 Smith-Waterman score: 5478; 100.0% identity (100.0% similar) in 801 aa overlap (1-801:1-801) 10 20 30 40 50 60 pF1KB4 MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 SDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQME 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 DSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 VGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 ENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 HPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 HPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 SPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 SPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 LESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 LNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVG 730 740 750 760 770 780 790 800 pF1KB4 TEDCRINSAVYSADESLSAHK ::::::::::::::::::::: NP_036 TEDCRINSAVYSADESLSAHK 790 800 >>XP_005268650 (OMIM: 605780) PREDICTED: PR domain zinc (808 aa) initn: 5464 init1: 2788 opt: 5454 Z-score: 3041.9 bits: 573.7 E(85289): 1.1e-162 Smith-Waterman score: 5454; 99.1% identity (99.1% similar) in 808 aa overlap (1-801:1-808) 10 20 30 40 50 60 pF1KB4 MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 SDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQME 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSI 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 VGAEV-------GVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLE ::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGAEVVGVLPLTGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLE 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 FCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 QQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 MCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDK 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB4 SFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB4 TNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEE 730 740 750 760 770 780 780 790 800 pF1KB4 DLADSVGTEDCRINSAVYSADESLSAHK :::::::::::::::::::::::::::: XP_005 DLADSVGTEDCRINSAVYSADESLSAHK 790 800 >>NP_078780 (OMIM: 611781) PR domain zinc finger protein (571 aa) initn: 444 init1: 266 opt: 576 Z-score: 342.7 bits: 73.8 E(85289): 2.4e-12 Smith-Waterman score: 576; 29.7% identity (60.8% similar) in 347 aa overlap (389-725:230-569) 360 370 380 390 400 410 pF1KB4 MEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQ :. . .:.: .. :.::. : : : NP_078 EDLHFVLYGVTPSLEHPASLHHAISGLLVPPDSSGSDSLPQT--LDKDSLQLPEGLCLMQ 200 210 220 230 240 250 420 430 440 450 460 470 pF1KB4 SIVGA--EVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCI .. : . ::. . : . :::. :. .. :: . :..: .:.:...: : . NP_078 TVFGEVPHFGVFCSSFIAKGVRFGPFQGKVVNASEVKTYGDNSV--MWEIFEDGHLSH-F 260 270 280 290 300 310 480 490 500 510 520 530 pF1KB4 ITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQI : . ::: .: :: .:::::: .:.::. . ..: ..::: .:. : . . NP_078 IDGKGGTGNWMSYVNCARFPKEQNLVAVQCQGHIFYESCKEIHQNQELLVWYGDCYEKFL 320 330 340 350 360 370 540 550 560 570 580 590 pF1KB4 GVPEHPDVHLCNCGKECNSYTE-----FKAHLTSHIHNHLPTQGHSGSHGPSHSK-ERKW .: .... . ::. .. .: .. . ... .. . . .. : .: .::. NP_078 DIPV--SLQVTEPGKQPSGPSEESAEGYRCERCGKVFTYKYYRDKHLKYTPCVDKGDRKF 380 390 400 410 420 430 600 610 620 630 640 pF1KB4 KCSMCPQAFISPSKLHVHFMG-HMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCT ::.: ..: . ..:..:.. : .::::. :.: ::. :.: :...:.:.. :.:. NP_078 PCSLCKRSFEKRDRLRIHILHVHEKHRPHKCSTCGKCFSQSSSLNKHMRVHSGDRPYQCV 440 450 460 470 480 490 650 660 670 680 690 700 pF1KB4 LCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVL-IHTQERQIKCPKCD : : :: .. :..:. :.::: .:: :: : : . .:: : .. .: : NP_078 YCTKRFTASSILRTHIRQHSGEKPFKCKYCGKSFASHAAHDSHVRRSHKEDDGCSCSICG 500 510 520 530 540 550 710 720 730 740 750 760 pF1KB4 KLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEED :.: . . .:.. :: NP_078 KIFSDQETFYSHMKFHEDY 560 570 >>XP_016873758 (OMIM: 605015) PREDICTED: zinc finger pro (592 aa) initn: 548 init1: 548 opt: 565 Z-score: 336.5 bits: 72.7 E(85289): 5.3e-12 Smith-Waterman score: 595; 31.6% identity (54.0% similar) in 376 aa overlap (404-754:158-508) 380 390 400 410 420 430 pF1KB4 TIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQ--LVLRQSIVGAEVGVWTGE :: ::. :. :....: . .: : XP_016 LETKTTQDYGREIYMSGSHGFQGGRYRLGISRKNLSMEKEQKLIVQHSYIPVE------E 130 140 150 160 170 180 440 450 460 470 480 pF1KB4 TIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCII----TTDENECNWM ..: . .: :.. . : . :. ::. . :.. :: :. XP_016 ALPQ---YVGVICQEDLLRDSMEEKYCGCNKCKGIYYWN--SRCVFHKRNQPGENLCQ-- 190 200 210 220 230 490 500 510 520 530 540 pF1KB4 MFVRKARNREEQNLVAYP--HDGKIFF-CTSQDIPPENELLFYYSRDYAQQIGVPEHPDV . :: ....: .: : :: .. : : .. :. :: : : XP_016 CSICKACFSQRSDLYRHPRNHIGKKLYGCDEVD------------GNFHQSSGVHFHQRV 240 250 260 270 280 550 560 570 580 pF1KB4 HL------CN-CGKECNSYTEFKAHLTSHIHNH---------LPTQGHSGSHGPSHSKER :. :: ::: .. . .. : : ... : .. : : :. XP_016 HIGEVPYSCNACGKSFSQISSLHNHQRVHTEEKFYKIECDKDLSRNSLLHIHQRLHIGEK 290 300 310 320 330 340 590 600 610 620 630 640 pF1KB4 KWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRC .::..: ..: : :::: : : ::.::: :.:.::. :::: : .:::.:.:.: XP_016 PFKCNQCGKSFNRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQLVHTGEKSYKC 350 360 370 380 390 400 650 660 670 680 690 700 pF1KB4 TLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCD : :.:::...:. :. .::::: ::: : : : . .::. : .:: :. ::.: XP_016 EDCGKGFTQRSNLQIHQRVHTGEKPYKCDDCGKDFSHSSDLRIHQRVHTGEKPYTCPECG 410 420 430 440 450 460 710 720 730 740 750 760 pF1KB4 KLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEED : : ....:. : : :.. : ::.: :.. . :: : .. : XP_016 KGFSKSSKLHTHQRVHTGEKPYKCEECGKGFSQRSHLLIHQRVHTGEKPYKCHDCGKGFS 470 480 490 500 510 520 770 780 790 800 pF1KB4 DSEEEDLADSVGTEDCRINSAVYSADESLSAHK XP_016 HSSNLHIHQRVHTGEKPYQCAKCGKGFSHSSALRIHQRVHAGEKPYKCREYYKGFDHNSH 530 540 550 560 570 580 >>XP_005253186 (OMIM: 605015) PREDICTED: zinc finger pro (592 aa) initn: 548 init1: 548 opt: 565 Z-score: 336.5 bits: 72.7 E(85289): 5.3e-12 Smith-Waterman score: 595; 31.6% identity (54.0% similar) in 376 aa overlap (404-754:158-508) 380 390 400 410 420 430 pF1KB4 TIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQ--LVLRQSIVGAEVGVWTGE :: ::. :. :....: . .: : XP_005 LETKTTQDYGREIYMSGSHGFQGGRYRLGISRKNLSMEKEQKLIVQHSYIPVE------E 130 140 150 160 170 180 440 450 460 470 480 pF1KB4 TIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCII----TTDENECNWM ..: . .: :.. . : . :. ::. . :.. :: :. XP_005 ALPQ---YVGVICQEDLLRDSMEEKYCGCNKCKGIYYWN--SRCVFHKRNQPGENLCQ-- 190 200 210 220 230 490 500 510 520 530 540 pF1KB4 MFVRKARNREEQNLVAYP--HDGKIFF-CTSQDIPPENELLFYYSRDYAQQIGVPEHPDV . :: ....: .: : :: .. : : .. :. :: : : XP_005 CSICKACFSQRSDLYRHPRNHIGKKLYGCDEVD------------GNFHQSSGVHFHQRV 240 250 260 270 280 550 560 570 580 pF1KB4 HL------CN-CGKECNSYTEFKAHLTSHIHNH---------LPTQGHSGSHGPSHSKER :. :: ::: .. . .. : : ... : .. : : :. XP_005 HIGEVPYSCNACGKSFSQISSLHNHQRVHTEEKFYKIECDKDLSRNSLLHIHQRLHIGEK 290 300 310 320 330 340 590 600 610 620 630 640 pF1KB4 KWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRC .::..: ..: : :::: : : ::.::: :.:.::. :::: : .:::.:.:.: XP_005 PFKCNQCGKSFNRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQLVHTGEKSYKC 350 360 370 380 390 400 650 660 670 680 690 700 pF1KB4 TLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCD : :.:::...:. :. .::::: ::: : : : . .::. : .:: :. ::.: XP_005 EDCGKGFTQRSNLQIHQRVHTGEKPYKCDDCGKDFSHSSDLRIHQRVHTGEKPYTCPECG 410 420 430 440 450 460 710 720 730 740 750 760 pF1KB4 KLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEED : : ....:. : : :.. : ::.: :.. . :: : .. : XP_005 KGFSKSSKLHTHQRVHTGEKPYKCEECGKGFSQRSHLLIHQRVHTGEKPYKCHDCGKGFS 470 480 490 500 510 520 770 780 790 800 pF1KB4 DSEEEDLADSVGTEDCRINSAVYSADESLSAHK XP_005 HSSNLHIHQRVHTGEKPYQCAKCGKGFSHSSALRIHQRVHAGEKPYKCREYYKGFDHNSH 530 540 550 560 570 580 >>XP_006718372 (OMIM: 605015) PREDICTED: zinc finger pro (592 aa) initn: 548 init1: 548 opt: 565 Z-score: 336.5 bits: 72.7 E(85289): 5.3e-12 Smith-Waterman score: 595; 31.6% identity (54.0% similar) in 376 aa overlap (404-754:158-508) 380 390 400 410 420 430 pF1KB4 TIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQ--LVLRQSIVGAEVGVWTGE :: ::. :. :....: . .: : XP_006 LETKTTQDYGREIYMSGSHGFQGGRYRLGISRKNLSMEKEQKLIVQHSYIPVE------E 130 140 150 160 170 180 440 450 460 470 480 pF1KB4 TIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCII----TTDENECNWM ..: . .: :.. . : . :. ::. . :.. :: :. XP_006 ALPQ---YVGVICQEDLLRDSMEEKYCGCNKCKGIYYWN--SRCVFHKRNQPGENLCQ-- 190 200 210 220 230 490 500 510 520 530 540 pF1KB4 MFVRKARNREEQNLVAYP--HDGKIFF-CTSQDIPPENELLFYYSRDYAQQIGVPEHPDV . :: ....: .: : :: .. : : .. :. :: : : XP_006 CSICKACFSQRSDLYRHPRNHIGKKLYGCDEVD------------GNFHQSSGVHFHQRV 240 250 260 270 280 550 560 570 580 pF1KB4 HL------CN-CGKECNSYTEFKAHLTSHIHNH---------LPTQGHSGSHGPSHSKER :. :: ::: .. . .. : : ... : .. : : :. XP_006 HIGEVPYSCNACGKSFSQISSLHNHQRVHTEEKFYKIECDKDLSRNSLLHIHQRLHIGEK 290 300 310 320 330 340 590 600 610 620 630 640 pF1KB4 KWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRC .::..: ..: : :::: : : ::.::: :.:.::. :::: : .:::.:.:.: XP_006 PFKCNQCGKSFNRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQLVHTGEKSYKC 350 360 370 380 390 400 650 660 670 680 690 700 pF1KB4 TLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCD : :.:::...:. :. .::::: ::: : : : . .::. : .:: :. ::.: XP_006 EDCGKGFTQRSNLQIHQRVHTGEKPYKCDDCGKDFSHSSDLRIHQRVHTGEKPYTCPECG 410 420 430 440 450 460 710 720 730 740 750 760 pF1KB4 KLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEED : : ....:. : : :.. : ::.: :.. . :: : .. : XP_006 KGFSKSSKLHTHQRVHTGEKPYKCEECGKGFSQRSHLLIHQRVHTGEKPYKCHDCGKGFS 470 480 490 500 510 520 770 780 790 800 pF1KB4 DSEEEDLADSVGTEDCRINSAVYSADESLSAHK XP_006 HSSNLHIHQRVHTGEKPYQCAKCGKGFSHSSALRIHQRVHAGEKPYKCREYYKGFDHNSH 530 540 550 560 570 580 >>XP_011518659 (OMIM: 605015) PREDICTED: zinc finger pro (592 aa) initn: 548 init1: 548 opt: 565 Z-score: 336.5 bits: 72.7 E(85289): 5.3e-12 Smith-Waterman score: 595; 31.6% identity (54.0% similar) in 376 aa overlap (404-754:158-508) 380 390 400 410 420 430 pF1KB4 TIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQ--LVLRQSIVGAEVGVWTGE :: ::. :. :....: . .: : XP_011 LETKTTQDYGREIYMSGSHGFQGGRYRLGISRKNLSMEKEQKLIVQHSYIPVE------E 130 140 150 160 170 180 440 450 460 470 480 pF1KB4 TIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCII----TTDENECNWM ..: . .: :.. . : . :. ::. . :.. :: :. XP_011 ALPQ---YVGVICQEDLLRDSMEEKYCGCNKCKGIYYWN--SRCVFHKRNQPGENLCQ-- 190 200 210 220 230 490 500 510 520 530 540 pF1KB4 MFVRKARNREEQNLVAYP--HDGKIFF-CTSQDIPPENELLFYYSRDYAQQIGVPEHPDV . :: ....: .: : :: .. : : .. :. :: : : XP_011 CSICKACFSQRSDLYRHPRNHIGKKLYGCDEVD------------GNFHQSSGVHFHQRV 240 250 260 270 280 550 560 570 580 pF1KB4 HL------CN-CGKECNSYTEFKAHLTSHIHNH---------LPTQGHSGSHGPSHSKER :. :: ::: .. . .. : : ... : .. : : :. XP_011 HIGEVPYSCNACGKSFSQISSLHNHQRVHTEEKFYKIECDKDLSRNSLLHIHQRLHIGEK 290 300 310 320 330 340 590 600 610 620 630 640 pF1KB4 KWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRC .::..: ..: : :::: : : ::.::: :.:.::. :::: : .:::.:.:.: XP_011 PFKCNQCGKSFNRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQLVHTGEKSYKC 350 360 370 380 390 400 650 660 670 680 690 700 pF1KB4 TLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCD : :.:::...:. :. .::::: ::: : : : . .::. : .:: :. ::.: XP_011 EDCGKGFTQRSNLQIHQRVHTGEKPYKCDDCGKDFSHSSDLRIHQRVHTGEKPYTCPECG 410 420 430 440 450 460 710 720 730 740 750 760 pF1KB4 KLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEED : : ....:. : : :.. : ::.: :.. . :: : .. : XP_011 KGFSKSSKLHTHQRVHTGEKPYKCEECGKGFSQRSHLLIHQRVHTGEKPYKCHDCGKGFS 470 480 490 500 510 520 770 780 790 800 pF1KB4 DSEEEDLADSVGTEDCRINSAVYSADESLSAHK XP_011 HSSNLHIHQRVHTGEKPYQCAKCGKGFSHSSALRIHQRVHAGEKPYKCREYYKGFDHNSH 530 540 550 560 570 580 >>XP_005253185 (OMIM: 605015) PREDICTED: zinc finger pro (606 aa) initn: 548 init1: 548 opt: 565 Z-score: 336.4 bits: 72.7 E(85289): 5.4e-12 Smith-Waterman score: 595; 31.6% identity (54.0% similar) in 376 aa overlap (404-754:172-522) 380 390 400 410 420 430 pF1KB4 TIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQ--LVLRQSIVGAEVGVWTGE :: ::. :. :....: . .: : XP_005 LETKTTQDYGREIYMSGSHGFQGGRYRLGISRKNLSMEKEQKLIVQHSYIPVE------E 150 160 170 180 190 440 450 460 470 480 pF1KB4 TIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCII----TTDENECNWM ..: . .: :.. . : . :. ::. . :.. :: :. XP_005 ALPQ---YVGVICQEDLLRDSMEEKYCGCNKCKGIYYWN--SRCVFHKRNQPGENLCQ-- 200 210 220 230 240 490 500 510 520 530 540 pF1KB4 MFVRKARNREEQNLVAYP--HDGKIFF-CTSQDIPPENELLFYYSRDYAQQIGVPEHPDV . :: ....: .: : :: .. : : .. :. :: : : XP_005 CSICKACFSQRSDLYRHPRNHIGKKLYGCDEVD------------GNFHQSSGVHFHQRV 250 260 270 280 290 550 560 570 580 pF1KB4 HL------CN-CGKECNSYTEFKAHLTSHIHNH---------LPTQGHSGSHGPSHSKER :. :: ::: .. . .. : : ... : .. : : :. XP_005 HIGEVPYSCNACGKSFSQISSLHNHQRVHTEEKFYKIECDKDLSRNSLLHIHQRLHIGEK 300 310 320 330 340 350 590 600 610 620 630 640 pF1KB4 KWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRC .::..: ..: : :::: : : ::.::: :.:.::. :::: : .:::.:.:.: XP_005 PFKCNQCGKSFNRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQLVHTGEKSYKC 360 370 380 390 400 410 650 660 670 680 690 700 pF1KB4 TLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCD : :.:::...:. :. .::::: ::: : : : . .::. : .:: :. ::.: XP_005 EDCGKGFTQRSNLQIHQRVHTGEKPYKCDDCGKDFSHSSDLRIHQRVHTGEKPYTCPECG 420 430 440 450 460 470 710 720 730 740 750 760 pF1KB4 KLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEED : : ....:. : : :.. : ::.: :.. . :: : .. : XP_005 KGFSKSSKLHTHQRVHTGEKPYKCEECGKGFSQRSHLLIHQRVHTGEKPYKCHDCGKGFS 480 490 500 510 520 530 770 780 790 800 pF1KB4 DSEEEDLADSVGTEDCRINSAVYSADESLSAHK XP_005 HSSNLHIHQRVHTGEKPYQCAKCGKGFSHSSALRIHQRVHAGEKPYKCREYYKGFDHNSH 540 550 560 570 580 590 >>XP_006718371 (OMIM: 605015) PREDICTED: zinc finger pro (606 aa) initn: 548 init1: 548 opt: 565 Z-score: 336.4 bits: 72.7 E(85289): 5.4e-12 Smith-Waterman score: 595; 31.6% identity (54.0% similar) in 376 aa overlap (404-754:172-522) 380 390 400 410 420 430 pF1KB4 TIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQ--LVLRQSIVGAEVGVWTGE :: ::. :. :....: . .: : XP_006 LETKTTQDYGREIYMSGSHGFQGGRYRLGISRKNLSMEKEQKLIVQHSYIPVE------E 150 160 170 180 190 440 450 460 470 480 pF1KB4 TIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCII----TTDENECNWM ..: . .: :.. . : . :. ::. . :.. :: :. XP_006 ALPQ---YVGVICQEDLLRDSMEEKYCGCNKCKGIYYWN--SRCVFHKRNQPGENLCQ-- 200 210 220 230 240 490 500 510 520 530 540 pF1KB4 MFVRKARNREEQNLVAYP--HDGKIFF-CTSQDIPPENELLFYYSRDYAQQIGVPEHPDV . :: ....: .: : :: .. : : .. :. :: : : XP_006 CSICKACFSQRSDLYRHPRNHIGKKLYGCDEVD------------GNFHQSSGVHFHQRV 250 260 270 280 290 550 560 570 580 pF1KB4 HL------CN-CGKECNSYTEFKAHLTSHIHNH---------LPTQGHSGSHGPSHSKER :. :: ::: .. . .. : : ... : .. : : :. XP_006 HIGEVPYSCNACGKSFSQISSLHNHQRVHTEEKFYKIECDKDLSRNSLLHIHQRLHIGEK 300 310 320 330 340 350 590 600 610 620 630 640 pF1KB4 KWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRC .::..: ..: : :::: : : ::.::: :.:.::. :::: : .:::.:.:.: XP_006 PFKCNQCGKSFNRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQLVHTGEKSYKC 360 370 380 390 400 410 650 660 670 680 690 700 pF1KB4 TLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCD : :.:::...:. :. .::::: ::: : : : . .::. : .:: :. ::.: XP_006 EDCGKGFTQRSNLQIHQRVHTGEKPYKCDDCGKDFSHSSDLRIHQRVHTGEKPYTCPECG 420 430 440 450 460 470 710 720 730 740 750 760 pF1KB4 KLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEED : : ....:. : : :.. : ::.: :.. . :: : .. : XP_006 KGFSKSSKLHTHQRVHTGEKPYKCEECGKGFSQRSHLLIHQRVHTGEKPYKCHDCGKGFS 480 490 500 510 520 530 770 780 790 800 pF1KB4 DSEEEDLADSVGTEDCRINSAVYSADESLSAHK XP_006 HSSNLHIHQRVHTGEKPYQCAKCGKGFSHSSALRIHQRVHAGEKPYKCREYYKGFDHNSH 540 550 560 570 580 590 >>NP_037381 (OMIM: 605015) zinc finger protein 214 [Homo (606 aa) initn: 548 init1: 548 opt: 565 Z-score: 336.4 bits: 72.7 E(85289): 5.4e-12 Smith-Waterman score: 595; 31.6% identity (54.0% similar) in 376 aa overlap (404-754:172-522) 380 390 400 410 420 430 pF1KB4 TIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQ--LVLRQSIVGAEVGVWTGE :: ::. :. :....: . .: : NP_037 LETKTTQDYGREIYMSGSHGFQGGRYRLGISRKNLSMEKEQKLIVQHSYIPVE------E 150 160 170 180 190 440 450 460 470 480 pF1KB4 TIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCII----TTDENECNWM ..: . .: :.. . : . :. ::. . :.. :: :. NP_037 ALPQ---YVGVICQEDLLRDSMEEKYCGCNKCKGIYYWN--SRCVFHKRNQPGENLCQ-- 200 210 220 230 240 490 500 510 520 530 540 pF1KB4 MFVRKARNREEQNLVAYP--HDGKIFF-CTSQDIPPENELLFYYSRDYAQQIGVPEHPDV . :: ....: .: : :: .. : : .. :. :: : : NP_037 CSICKACFSQRSDLYRHPRNHIGKKLYGCDEVD------------GNFHQSSGVHFHQRV 250 260 270 280 290 550 560 570 580 pF1KB4 HL------CN-CGKECNSYTEFKAHLTSHIHNH---------LPTQGHSGSHGPSHSKER :. :: ::: .. . .. : : ... : .. : : :. NP_037 HIGEVPYSCNACGKSFSQISSLHNHQRVHTEEKFYKIECDKDLSRNSLLHIHQRLHIGEK 300 310 320 330 340 350 590 600 610 620 630 640 pF1KB4 KWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRC .::..: ..: : :::: : : ::.::: :.:.::. :::: : .:::.:.:.: NP_037 PFKCNQCGKSFNRSSVLHVHQRVHTGEKPYKCDECGKGFSQSSNLRIHQLVHTGEKSYKC 360 370 380 390 400 410 650 660 670 680 690 700 pF1KB4 TLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCD : :.:::...:. :. .::::: ::: : : : . .::. : .:: :. ::.: NP_037 EDCGKGFTQRSNLQIHQRVHTGEKPYKCDDCGKDFSHSSDLRIHQRVHTGEKPYTCPECG 420 430 440 450 460 470 710 720 730 740 750 760 pF1KB4 KLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEED : : ....:. : : :.. : ::.: :.. . :: : .. : NP_037 KGFSKSSKLHTHQRVHTGEKPYKCEECGKGFSQRSHLLIHQRVHTGEKPYKCHDCGKGFS 480 490 500 510 520 530 770 780 790 800 pF1KB4 DSEEEDLADSVGTEDCRINSAVYSADESLSAHK NP_037 HSSNLHIHQRVHTGEKPYQCAKCGKGFSHSSALRIHQRVHAGEKPYKCREYYKGFDHNSH 540 550 560 570 580 590 801 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:40:18 2016 done: Thu Nov 3 15:40:20 2016 Total Scan time: 12.640 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]