FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4985, 535 aa 1>>>pF1KB4985 535 - 535 aa - 535 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5481+/-0.000475; mu= 16.9099+/- 0.030 mean_var=64.9869+/-13.559, 0's: 0 Z-trim(106.2): 74 B-trim: 0 in 0/51 Lambda= 0.159097 statistics sampled from 14258 (14329) to 14258 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.503), E-opt: 0.2 (0.168), width: 16 Scan time: 9.020 The best scores are: opt bits E(85289) NP_006422 (OMIM: 605139) T-complex protein 1 subun ( 535) 3368 782.7 0 NP_001185771 (OMIM: 605139) T-complex protein 1 su ( 488) 3082 717.0 3.1e-206 NP_006420 (OMIM: 605140) T-complex protein 1 subun ( 543) 1012 241.9 3.7e-63 NP_001293082 (OMIM: 256840,610150) T-complex prote ( 520) 941 225.6 2.8e-58 NP_036205 (OMIM: 256840,610150) T-complex protein ( 541) 938 225.0 4.7e-58 NP_001293085 (OMIM: 256840,610150) T-complex prote ( 503) 937 224.7 5.2e-58 XP_011530781 (OMIM: 605140) PREDICTED: T-complex p ( 499) 934 224.0 8.3e-58 NP_001159757 (OMIM: 605140) T-complex protein 1 su ( 499) 934 224.0 8.3e-58 XP_011530780 (OMIM: 605140) PREDICTED: T-complex p ( 499) 934 224.0 8.3e-58 NP_006421 (OMIM: 605142) T-complex protein 1 subun ( 539) 843 203.1 1.7e-51 NP_001159756 (OMIM: 605140) T-complex protein 1 su ( 456) 798 192.8 1.9e-48 NP_005989 (OMIM: 600114) T-complex protein 1 subun ( 545) 795 192.1 3.6e-48 NP_001293084 (OMIM: 256840,610150) T-complex prote ( 448) 697 169.6 1.8e-41 NP_001293083 (OMIM: 256840,610150) T-complex prote ( 486) 697 169.6 1.9e-41 NP_001008800 (OMIM: 600114) T-complex protein 1 su ( 507) 683 166.4 1.9e-40 NP_001243650 (OMIM: 605142) T-complex protein 1 su ( 509) 670 163.4 1.5e-39 NP_110379 (OMIM: 186980) T-complex protein 1 subun ( 556) 653 159.5 2.4e-38 NP_001753 (OMIM: 104613) T-complex protein 1 subun ( 531) 622 152.4 3.2e-36 NP_006575 (OMIM: 610730) T-complex protein 1 subun ( 530) 615 150.8 9.7e-36 NP_001008897 (OMIM: 186980) T-complex protein 1 su ( 401) 555 137.0 1.1e-31 NP_001009570 (OMIM: 605140) T-complex protein 1 su ( 339) 545 134.7 4.5e-31 XP_016879512 (OMIM: 610730) PREDICTED: T-complex p ( 464) 505 125.5 3.4e-28 XP_011522505 (OMIM: 610730) PREDICTED: T-complex p ( 388) 405 102.6 2.4e-21 NP_001180459 (OMIM: 610730) T-complex protein 1 su ( 485) 406 102.8 2.5e-21 NP_001009186 (OMIM: 104613) T-complex protein 1 su ( 486) 400 101.4 6.4e-21 XP_016879513 (OMIM: 610730) PREDICTED: T-complex p ( 351) 376 95.9 2.2e-19 NP_001180458 (OMIM: 610730) T-complex protein 1 su ( 493) 376 95.9 3e-19 NP_002147 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 194 54.2 1.3e-06 NP_955472 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 194 54.2 1.3e-06 NP_740754 (OMIM: 209900,236700,604896,605231) McKu ( 570) 172 49.1 4.2e-05 NP_061336 (OMIM: 209900,236700,604896,605231) McKu ( 570) 172 49.1 4.2e-05 XP_016859060 (OMIM: 121850,609414) PREDICTED: 1-ph (1895) 160 46.6 0.00082 XP_016859059 (OMIM: 121850,609414) PREDICTED: 1-ph (1945) 160 46.6 0.00084 XP_011509086 (OMIM: 121850,609414) PREDICTED: 1-ph (2053) 160 46.6 0.00088 XP_011509085 (OMIM: 121850,609414) PREDICTED: 1-ph (2054) 160 46.6 0.00088 XP_011509094 (OMIM: 121850,609414) PREDICTED: 1-ph (1340) 156 45.6 0.0011 XP_016859063 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 156 45.7 0.0015 XP_011509092 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 156 45.7 0.0015 XP_016859061 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 156 45.7 0.0015 XP_016859062 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 156 45.7 0.0015 XP_011509091 (OMIM: 121850,609414) PREDICTED: 1-ph (1951) 156 45.7 0.0016 XP_011509090 (OMIM: 121850,609414) PREDICTED: 1-ph (2001) 156 45.7 0.0016 XP_011509089 (OMIM: 121850,609414) PREDICTED: 1-ph (2012) 156 45.7 0.0016 XP_011509088 (OMIM: 121850,609414) PREDICTED: 1-ph (2013) 156 45.7 0.0016 XP_016859058 (OMIM: 121850,609414) PREDICTED: 1-ph (2036) 156 45.7 0.0016 XP_011509087 (OMIM: 121850,609414) PREDICTED: 1-ph (2048) 156 45.7 0.0017 XP_011509084 (OMIM: 121850,609414) PREDICTED: 1-ph (2055) 156 45.7 0.0017 XP_016859057 (OMIM: 121850,609414) PREDICTED: 1-ph (2092) 156 45.7 0.0017 NP_055855 (OMIM: 121850,609414) 1-phosphatidylinos (2098) 156 45.7 0.0017 XP_011509083 (OMIM: 121850,609414) PREDICTED: 1-ph (2104) 156 45.7 0.0017 >>NP_006422 (OMIM: 605139) T-complex protein 1 subunit b (535 aa) initn: 3368 init1: 3368 opt: 3368 Z-score: 4177.6 bits: 782.7 E(85289): 0 Smith-Waterman score: 3368; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535) 10 20 30 40 50 60 pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM 430 440 450 460 470 480 490 500 510 520 530 pF1KB4 REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC 490 500 510 520 530 >>NP_001185771 (OMIM: 605139) T-complex protein 1 subuni (488 aa) initn: 3082 init1: 3082 opt: 3082 Z-score: 3823.5 bits: 717.0 E(85289): 3.1e-206 Smith-Waterman score: 3082; 100.0% identity (100.0% similar) in 488 aa overlap (48-535:1-488) 20 30 40 50 60 70 pF1KB4 EERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVD :::::::::::::::::::::::::::::: NP_001 MDKILLSSGRDASLMVTNDGATILKNIGVD 10 20 30 80 90 100 110 120 130 pF1KB4 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 REALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLE 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 AIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVR 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 VDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADF 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 AGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRG 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 ATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAME 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 SYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESF 400 410 420 430 440 450 500 510 520 530 pF1KB4 QVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC :::::::::::::::::::::::::::::::::::::: NP_001 QVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC 460 470 480 >>NP_006420 (OMIM: 605140) T-complex protein 1 subunit e (543 aa) initn: 897 init1: 455 opt: 1012 Z-score: 1255.0 bits: 241.9 E(85289): 3.7e-63 Smith-Waterman score: 1012; 35.8% identity (67.0% similar) in 528 aa overlap (8-529:5-527) 10 20 30 40 50 pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAI-AIGDLVKSTLGPKGMDKILLSSGRDA :: ..: :.: .. .:.: :.: .:.. :..::::.:::: :. .:: NP_006 MMPTPVILLKEGTDSSQG-IPQLVSNISACQVIAEAVRTTLGPRGMDK-LIVDGRGK 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 SLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAK . ..:::::::: . : .::::.:::... :: ::::::::::.::::.:.... . . NP_006 AT-ISNDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 KIHPQTIIAGWREATKAAREALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDH .::: :: ..: ::. : . . :: . .:.:. :. : . : :.:::::....: NP_006 GLHPQIIIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 FTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIEN :.:..:.::. : .:. : : : ::.: :: : : . : .. :::. .: NP_006 FAKMVVDAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 AKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQ :: . :. .. : . ....:: .. : :: . . .:.:.: . : . ... NP_006 PKIALLNVELEL-KAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMI : . : :. .. .. ..: .. :: : .. . :: :...::..: NP_006 PIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQI 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 GEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSE : .. :.: ...::..:::...:...:.:::::::. .. ...:.. .: ::: : NP_006 GGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIE 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 MLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNT : ... . . . :::. . . .:::::...: . ::::.:..... .::: :..:.: NP_006 MELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGT 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB4 TAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHP :.:. . :.: . : .:. ..: .:.::: .:. ::. :: ::. : NP_006 WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTA 480 490 500 510 520 530 pF1KB4 C NP_006 AGRGRGRGRPH 540 >>NP_001293082 (OMIM: 256840,610150) T-complex protein 1 (520 aa) initn: 689 init1: 299 opt: 941 Z-score: 1167.2 bits: 225.6 E(85289): 2.8e-58 Smith-Waterman score: 941; 34.3% identity (69.6% similar) in 510 aa overlap (22-522:10-514) 10 20 30 40 50 60 pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS : .. ...: :... ....:::.:.::.... .:.. NP_001 MNSSLGPTIEKLSVSHIMAAKAVANTMRTSLGPNGLDKMMVD--KDGD 10 20 30 40 70 80 90 100 110 120 pF1KB4 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK . :::::::::. . ::. ::..:..:. ::::.:::::.:.:::. ::.:::.:. . NP_001 VTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT ::: : :...:...: : : .. : ..: . :.. : :::.::... . ... NP_001 IHPIRIADGYEQAARVAIEHL-DKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMA 110 120 130 140 150 160 190 200 210 220 230 pF1KB4 KLAVEAVLRL----KGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQ-PKRIENA ..::.::: . . . ..: :.. :.:: : :. : .: ..:: .. : ::..:.: NP_001 EIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB4 KILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQL :: : . .. : : .. : :. ... ::::..: ...: . : : : . NP_001 KIAILTCPFEPPKPKT-KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWG 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 IYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIG . . ..:. .. :.. . .: .:..:::.:. :.. ::: :..:. .: NP_001 FDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFG 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB4 --EDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCS .::.. . ..: :: .::....:..::.:::::::::. . ..:.:.::::: . NP_001 TTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAA 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB4 EMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAH-SEG :. : ::.: :.. : : ::...: ::...: ...:.:.. . ....:: . .: NP_001 EISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEM 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB4 NTTAGLD-MREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPD : . :.: ...:: .:: . :.. :.: . :.. ...::..:.: : NP_001 NPALGIDCLHKGT-NDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE 470 480 490 500 510 520 pF1KB4 HHPC >>NP_036205 (OMIM: 256840,610150) T-complex protein 1 su (541 aa) initn: 689 init1: 299 opt: 938 Z-score: 1163.2 bits: 225.0 E(85289): 4.7e-58 Smith-Waterman score: 938; 34.5% identity (69.9% similar) in 505 aa overlap (27-522:36-535) 10 20 30 40 50 pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSG . ...: :... ....:::.:.::.... NP_036 TLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVD-- 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 RDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESL .:... :::::::::. . ::. ::..:..:. ::::.:::::.:.:::. ::.:::.: NP_036 KDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 IAKKIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHK . . ::: : :...:...: : : .. : ..: . :.. : :::.::... . NP_036 LDRGIHPIRIADGYEQAARVAIEHL-DKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 DHFTKLAVEAVLRL----KGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQ-PKR .....::.::: . . . ..: :.. :.:: : :. : .: ..:: .. : ::. NP_036 RQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 IENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFI .:.::: : . .. : : .. : :. ... ::::..: ...: . : : : NP_036 VEDAKIAILTCPFEPPKPKT-KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 NRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEE . . . ..:. .. :.. . .: .:..:::.:. :.. ::: :..: NP_036 CQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQE 310 320 330 340 350 360 360 370 380 390 400 pF1KB4 VMIG--EDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYG . .: .::.. . ..: :: .::....:..::.:::::::::. . ..:.:.::: NP_036 ISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYG 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB4 GGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAH :: .:. : ::.: :.. : : ::...: ::...: ...:.:.. . ....:: . NP_036 GGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQ 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB4 -SEGNTTAGLD-MREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK .: : . :.: ...:: .:: . :.. :.: . :.. ...::..:.: : NP_036 VKEMNPALGIDCLHKGT-NDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESE 490 500 510 520 530 540 530 pF1KB4 RVPDHHPC NP_036 E >>NP_001293085 (OMIM: 256840,610150) T-complex protein 1 (503 aa) initn: 689 init1: 299 opt: 937 Z-score: 1162.4 bits: 224.7 E(85289): 5.2e-58 Smith-Waterman score: 937; 34.7% identity (69.9% similar) in 502 aa overlap (30-522:1-497) 10 20 30 40 50 60 pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS ..: :... ....:::.:.::.... .:.. NP_001 MAAKAVANTMRTSLGPNGLDKMMVD--KDGD 10 20 70 80 90 100 110 120 pF1KB4 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK . :::::::::. . ::. ::..:..:. ::::.:::::.:.:::. ::.:::.:. . NP_001 VTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRG 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB4 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT ::: : :...:...: : : .. : ..: . :.. : :::.::... . ... NP_001 IHPIRIADGYEQAARVAIEHL-DKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMA 90 100 110 120 130 140 190 200 210 220 230 pF1KB4 KLAVEAVLRL----KGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQ-PKRIENA ..::.::: . . . ..: :.. :.:: : :. : .: ..:: .. : ::..:.: NP_001 EIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDA 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB4 KILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQL :: : . .. : : .. : :. ... ::::..: ...: . : : : . NP_001 KIAILTCPFEPPKPKT-KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWG 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB4 IYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIG . . ..:. .. :.. . .: .:..:::.:. :.. ::: :..:. .: NP_001 FDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFG 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB4 --EDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCS .::.. . ..: :: .::....:..::.:::::::::. . ..:.:.::::: . NP_001 TTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAA 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB4 EMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAH-SEG :. : ::.: :.. : : ::...: ::...: ...:.:.. . ....:: . .: NP_001 EISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEM 390 400 410 420 430 440 480 490 500 510 520 530 pF1KB4 NTTAGLD-MREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPD : . :.: ...:: .:: . :.. :.: . :.. ...::..:.: : NP_001 NPALGIDCLHKGT-NDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE 450 460 470 480 490 500 pF1KB4 HHPC >>XP_011530781 (OMIM: 605140) PREDICTED: T-complex prote (499 aa) initn: 846 init1: 455 opt: 934 Z-score: 1158.8 bits: 224.0 E(85289): 8.3e-58 Smith-Waterman score: 934; 35.3% identity (66.7% similar) in 487 aa overlap (48-529:1-483) 20 30 40 50 60 70 pF1KB4 EERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVD :::.... :: . ..:::::::: . : XP_011 MDKLIVD-GRGKAT-ISNDGATILKLLDVV 10 20 80 90 100 110 120 130 pF1KB4 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA .::::.:::... :: ::::::::::.::::.:.... . . .::: :: ..: ::. : XP_011 HPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLA 30 40 50 60 70 80 140 150 160 170 180 190 pF1KB4 REALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNL . . :: . .:.:. :. : . : :.:::::....: :.:..:.::. : .: XP_011 VNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQL 90 100 110 120 130 140 200 210 220 230 240 250 pF1KB4 EAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIENAKILIANTGMDTDKIKIF . : : : ::.: :: : : . : .. :::. .: :: . :. .. : . XP_011 KMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKD 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB4 GSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAI ....:: .. : :: . . .:.:.: . : . ... : . : :. .. XP_011 NAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCA 210 220 230 240 250 260 320 330 340 350 360 370 pF1KB4 EHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACT .. ..: .. :: : .. . :: :...::..:: .. :.: ...:: XP_011 GRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCT 270 280 290 300 310 320 380 390 400 410 420 430 pF1KB4 IVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE ..:::...:...:.:::::::. .. ...:.. .: ::: :: ... . . . :::. XP_011 FILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQ 330 340 350 360 370 380 440 450 460 470 480 490 pF1KB4 AVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILG . . .:::::...: . ::::.:..... .::: :..:.: :.:. . :.: XP_011 QLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAF 390 400 410 420 430 440 500 510 520 530 pF1KB4 ITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC . : .:. ..: .:.::: .:. ::. :: ::. : XP_011 VWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAGRGRGRGRPH 450 460 470 480 490 >>NP_001159757 (OMIM: 605140) T-complex protein 1 subuni (499 aa) initn: 846 init1: 455 opt: 934 Z-score: 1158.8 bits: 224.0 E(85289): 8.3e-58 Smith-Waterman score: 934; 35.3% identity (66.7% similar) in 487 aa overlap (48-529:1-483) 20 30 40 50 60 70 pF1KB4 EERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVD :::.... :: . ..:::::::: . : NP_001 MDKLIVD-GRGKAT-ISNDGATILKLLDVV 10 20 80 90 100 110 120 130 pF1KB4 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA .::::.:::... :: ::::::::::.::::.:.... . . .::: :: ..: ::. : NP_001 HPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLA 30 40 50 60 70 80 140 150 160 170 180 190 pF1KB4 REALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNL . . :: . .:.:. :. : . : :.:::::....: :.:..:.::. : .: NP_001 VNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQL 90 100 110 120 130 140 200 210 220 230 240 250 pF1KB4 EAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIENAKILIANTGMDTDKIKIF . : : : ::.: :: : : . : .. :::. .: :: . :. .. : . NP_001 KMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKD 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB4 GSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAI ....:: .. : :: . . .:.:.: . : . ... : . : :. .. NP_001 NAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCA 210 220 230 240 250 260 320 330 340 350 360 370 pF1KB4 EHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACT .. ..: .. :: : .. . :: :...::..:: .. :.: ...:: NP_001 GRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCT 270 280 290 300 310 320 380 390 400 410 420 430 pF1KB4 IVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE ..:::...:...:.:::::::. .. ...:.. .: ::: :: ... . . . :::. NP_001 FILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQ 330 340 350 360 370 380 440 450 460 470 480 490 pF1KB4 AVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILG . . .:::::...: . ::::.:..... .::: :..:.: :.:. . :.: NP_001 QLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAF 390 400 410 420 430 440 500 510 520 530 pF1KB4 ITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC . : .:. ..: .:.::: .:. ::. :: ::. : NP_001 VWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAGRGRGRGRPH 450 460 470 480 490 >>XP_011530780 (OMIM: 605140) PREDICTED: T-complex prote (499 aa) initn: 846 init1: 455 opt: 934 Z-score: 1158.8 bits: 224.0 E(85289): 8.3e-58 Smith-Waterman score: 934; 35.3% identity (66.7% similar) in 487 aa overlap (48-529:1-483) 20 30 40 50 60 70 pF1KB4 EERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVD :::.... :: . ..:::::::: . : XP_011 MDKLIVD-GRGKAT-ISNDGATILKLLDVV 10 20 80 90 100 110 120 130 pF1KB4 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA .::::.:::... :: ::::::::::.::::.:.... . . .::: :: ..: ::. : XP_011 HPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLA 30 40 50 60 70 80 140 150 160 170 180 190 pF1KB4 REALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNL . . :: . .:.:. :. : . : :.:::::....: :.:..:.::. : .: XP_011 VNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQL 90 100 110 120 130 140 200 210 220 230 240 250 pF1KB4 EAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIENAKILIANTGMDTDKIKIF . : : : ::.: :: : : . : .. :::. .: :: . :. .. : . XP_011 KMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKD 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB4 GSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAI ....:: .. : :: . . .:.:.: . : . ... : . : :. .. XP_011 NAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCA 210 220 230 240 250 260 320 330 340 350 360 370 pF1KB4 EHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACT .. ..: .. :: : .. . :: :...::..:: .. :.: ...:: XP_011 GRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCT 270 280 290 300 310 320 380 390 400 410 420 430 pF1KB4 IVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE ..:::...:...:.:::::::. .. ...:.. .: ::: :: ... . . . :::. XP_011 FILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQ 330 340 350 360 370 380 440 450 460 470 480 490 pF1KB4 AVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILG . . .:::::...: . ::::.:..... .::: :..:.: :.:. . :.: XP_011 QLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAF 390 400 410 420 430 440 500 510 520 530 pF1KB4 ITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC . : .:. ..: .:.::: .:. ::. :: ::. : XP_011 VWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAGRGRGRGRPH 450 460 470 480 490 >>NP_006421 (OMIM: 605142) T-complex protein 1 subunit d (539 aa) initn: 738 init1: 345 opt: 843 Z-score: 1045.4 bits: 203.1 E(85289): 1.7e-51 Smith-Waterman score: 902; 32.2% identity (67.4% similar) in 522 aa overlap (14-521:23-536) 10 20 30 40 50 pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKI : :... :.... .: :..: ....::::::::. NP_006 MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 LLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLR . .. :.. .:::::::::.. : .:::..::..:..:: :.:::::::...:. :: NP_006 IQDGKGDVT--ITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLD 70 80 90 100 110 120 130 140 150 160 pF1KB4 EAESLIAKKIHPQTIIAGWREATKAAREAL--LSSAVDHGSDEVKFRQDLMNIAGTTLSS .:. : ::: : ....: . . : : .: :. :: :. :.: : :.:.: NP_006 SCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVEL-SD----RETLLNSATTSLNS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB4 KLLTHHKDHFTKLAVEAVLRL-----KGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKI :....... .. ..:.::... : .:. :.:.:::::.. : : ::..: .:. NP_006 KVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKV 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB4 GVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILK . . :.:.::: . . ... : . ... :.. :.. .. . :. . . :..: : NP_006 SNSGITRVEKAKIGLIQFCLSAPKTDM-DNQIVVSDYAQMDRVLREERAYILNLVKQIKK 240 250 260 270 280 290 290 300 310 320 330 pF1KB4 HGINCF-----INRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPE : : . : :. . . .... .:.:. . .: . . : . .. .:. NP_006 TGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFT 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB4 LVKLGSCKLIEEVMI-GEDKLIHFSGVAL-GEACTIVLRGATQQILDEAERSLHDALCVL ::: .: ::: . : ::....: : :.. :::.::... ...:::::.::::::. NP_006 ADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVI 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB4 AQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYD :: . ::: :. .: .:. . : :. ....: :....:. .:.::: . NP_006 RCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLN 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB4 SADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRV . :..:: :..:. :::...:.: :... ... . :. ..: :.:... ::.. NP_006 PISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKI 480 490 500 510 520 530 520 530 pF1KB4 DNIIKAAPRKRVPDHHPC :... NP_006 DDVVNTR 535 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:40:58 2016 done: Thu Nov 3 15:40:59 2016 Total Scan time: 9.020 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]