FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4985, 535 aa
1>>>pF1KB4985 535 - 535 aa - 535 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5481+/-0.000475; mu= 16.9099+/- 0.030
mean_var=64.9869+/-13.559, 0's: 0 Z-trim(106.2): 74 B-trim: 0 in 0/51
Lambda= 0.159097
statistics sampled from 14258 (14329) to 14258 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.503), E-opt: 0.2 (0.168), width: 16
Scan time: 9.020
The best scores are: opt bits E(85289)
NP_006422 (OMIM: 605139) T-complex protein 1 subun ( 535) 3368 782.7 0
NP_001185771 (OMIM: 605139) T-complex protein 1 su ( 488) 3082 717.0 3.1e-206
NP_006420 (OMIM: 605140) T-complex protein 1 subun ( 543) 1012 241.9 3.7e-63
NP_001293082 (OMIM: 256840,610150) T-complex prote ( 520) 941 225.6 2.8e-58
NP_036205 (OMIM: 256840,610150) T-complex protein ( 541) 938 225.0 4.7e-58
NP_001293085 (OMIM: 256840,610150) T-complex prote ( 503) 937 224.7 5.2e-58
XP_011530781 (OMIM: 605140) PREDICTED: T-complex p ( 499) 934 224.0 8.3e-58
NP_001159757 (OMIM: 605140) T-complex protein 1 su ( 499) 934 224.0 8.3e-58
XP_011530780 (OMIM: 605140) PREDICTED: T-complex p ( 499) 934 224.0 8.3e-58
NP_006421 (OMIM: 605142) T-complex protein 1 subun ( 539) 843 203.1 1.7e-51
NP_001159756 (OMIM: 605140) T-complex protein 1 su ( 456) 798 192.8 1.9e-48
NP_005989 (OMIM: 600114) T-complex protein 1 subun ( 545) 795 192.1 3.6e-48
NP_001293084 (OMIM: 256840,610150) T-complex prote ( 448) 697 169.6 1.8e-41
NP_001293083 (OMIM: 256840,610150) T-complex prote ( 486) 697 169.6 1.9e-41
NP_001008800 (OMIM: 600114) T-complex protein 1 su ( 507) 683 166.4 1.9e-40
NP_001243650 (OMIM: 605142) T-complex protein 1 su ( 509) 670 163.4 1.5e-39
NP_110379 (OMIM: 186980) T-complex protein 1 subun ( 556) 653 159.5 2.4e-38
NP_001753 (OMIM: 104613) T-complex protein 1 subun ( 531) 622 152.4 3.2e-36
NP_006575 (OMIM: 610730) T-complex protein 1 subun ( 530) 615 150.8 9.7e-36
NP_001008897 (OMIM: 186980) T-complex protein 1 su ( 401) 555 137.0 1.1e-31
NP_001009570 (OMIM: 605140) T-complex protein 1 su ( 339) 545 134.7 4.5e-31
XP_016879512 (OMIM: 610730) PREDICTED: T-complex p ( 464) 505 125.5 3.4e-28
XP_011522505 (OMIM: 610730) PREDICTED: T-complex p ( 388) 405 102.6 2.4e-21
NP_001180459 (OMIM: 610730) T-complex protein 1 su ( 485) 406 102.8 2.5e-21
NP_001009186 (OMIM: 104613) T-complex protein 1 su ( 486) 400 101.4 6.4e-21
XP_016879513 (OMIM: 610730) PREDICTED: T-complex p ( 351) 376 95.9 2.2e-19
NP_001180458 (OMIM: 610730) T-complex protein 1 su ( 493) 376 95.9 3e-19
NP_002147 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 194 54.2 1.3e-06
NP_955472 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 194 54.2 1.3e-06
NP_740754 (OMIM: 209900,236700,604896,605231) McKu ( 570) 172 49.1 4.2e-05
NP_061336 (OMIM: 209900,236700,604896,605231) McKu ( 570) 172 49.1 4.2e-05
XP_016859060 (OMIM: 121850,609414) PREDICTED: 1-ph (1895) 160 46.6 0.00082
XP_016859059 (OMIM: 121850,609414) PREDICTED: 1-ph (1945) 160 46.6 0.00084
XP_011509086 (OMIM: 121850,609414) PREDICTED: 1-ph (2053) 160 46.6 0.00088
XP_011509085 (OMIM: 121850,609414) PREDICTED: 1-ph (2054) 160 46.6 0.00088
XP_011509094 (OMIM: 121850,609414) PREDICTED: 1-ph (1340) 156 45.6 0.0011
XP_016859063 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 156 45.7 0.0015
XP_011509092 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 156 45.7 0.0015
XP_016859061 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 156 45.7 0.0015
XP_016859062 (OMIM: 121850,609414) PREDICTED: 1-ph (1779) 156 45.7 0.0015
XP_011509091 (OMIM: 121850,609414) PREDICTED: 1-ph (1951) 156 45.7 0.0016
XP_011509090 (OMIM: 121850,609414) PREDICTED: 1-ph (2001) 156 45.7 0.0016
XP_011509089 (OMIM: 121850,609414) PREDICTED: 1-ph (2012) 156 45.7 0.0016
XP_011509088 (OMIM: 121850,609414) PREDICTED: 1-ph (2013) 156 45.7 0.0016
XP_016859058 (OMIM: 121850,609414) PREDICTED: 1-ph (2036) 156 45.7 0.0016
XP_011509087 (OMIM: 121850,609414) PREDICTED: 1-ph (2048) 156 45.7 0.0017
XP_011509084 (OMIM: 121850,609414) PREDICTED: 1-ph (2055) 156 45.7 0.0017
XP_016859057 (OMIM: 121850,609414) PREDICTED: 1-ph (2092) 156 45.7 0.0017
NP_055855 (OMIM: 121850,609414) 1-phosphatidylinos (2098) 156 45.7 0.0017
XP_011509083 (OMIM: 121850,609414) PREDICTED: 1-ph (2104) 156 45.7 0.0017
>>NP_006422 (OMIM: 605139) T-complex protein 1 subunit b (535 aa)
initn: 3368 init1: 3368 opt: 3368 Z-score: 4177.6 bits: 782.7 E(85289): 0
Smith-Waterman score: 3368; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535)
10 20 30 40 50 60
pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM
430 440 450 460 470 480
490 500 510 520 530
pF1KB4 REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
490 500 510 520 530
>>NP_001185771 (OMIM: 605139) T-complex protein 1 subuni (488 aa)
initn: 3082 init1: 3082 opt: 3082 Z-score: 3823.5 bits: 717.0 E(85289): 3.1e-206
Smith-Waterman score: 3082; 100.0% identity (100.0% similar) in 488 aa overlap (48-535:1-488)
20 30 40 50 60 70
pF1KB4 EERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVD
::::::::::::::::::::::::::::::
NP_001 MDKILLSSGRDASLMVTNDGATILKNIGVD
10 20 30
80 90 100 110 120 130
pF1KB4 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB4 REALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB4 AIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVR
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB4 VDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADF
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB4 AGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRG
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB4 ATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAME
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB4 SYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESF
400 410 420 430 440 450
500 510 520 530
pF1KB4 QVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
::::::::::::::::::::::::::::::::::::::
NP_001 QVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
460 470 480
>>NP_006420 (OMIM: 605140) T-complex protein 1 subunit e (543 aa)
initn: 897 init1: 455 opt: 1012 Z-score: 1255.0 bits: 241.9 E(85289): 3.7e-63
Smith-Waterman score: 1012; 35.8% identity (67.0% similar) in 528 aa overlap (8-529:5-527)
10 20 30 40 50
pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAI-AIGDLVKSTLGPKGMDKILLSSGRDA
:: ..: :.: .. .:.: :.: .:.. :..::::.:::: :. .::
NP_006 MMPTPVILLKEGTDSSQG-IPQLVSNISACQVIAEAVRTTLGPRGMDK-LIVDGRGK
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 SLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAK
. ..:::::::: . : .::::.:::... :: ::::::::::.::::.:.... . .
NP_006 AT-ISNDGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 KIHPQTIIAGWREATKAAREALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDH
.::: :: ..: ::. : . . :: . .:.:. :. : . : :.:::::....:
NP_006 GLHPQIIIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 FTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIEN
:.:..:.::. : .:. : : : ::.: :: : : . : .. :::. .:
NP_006 FAKMVVDAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 AKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQ
:: . :. .. : . ....:: .. : :: . . .:.:.: . : . ...
NP_006 PKIALLNVELEL-KAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 LIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMI
: . : :. .. .. ..: .. :: : .. . :: :...::..:
NP_006 PIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 GEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSE
: .. :.: ...::..:::...:...:.:::::::. .. ...:.. .: ::: :
NP_006 GGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIE
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB4 MLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNT
: ... . . . :::. . . .:::::...: . ::::.:..... .::: :..:.:
NP_006 MELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGT
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB4 TAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHP
:.:. . :.: . : .:. ..: .:.::: .:. ::. :: ::. :
NP_006 WYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTA
480 490 500 510 520 530
pF1KB4 C
NP_006 AGRGRGRGRPH
540
>>NP_001293082 (OMIM: 256840,610150) T-complex protein 1 (520 aa)
initn: 689 init1: 299 opt: 941 Z-score: 1167.2 bits: 225.6 E(85289): 2.8e-58
Smith-Waterman score: 941; 34.3% identity (69.6% similar) in 510 aa overlap (22-522:10-514)
10 20 30 40 50 60
pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS
: .. ...: :... ....:::.:.::.... .:..
NP_001 MNSSLGPTIEKLSVSHIMAAKAVANTMRTSLGPNGLDKMMVD--KDGD
10 20 30 40
70 80 90 100 110 120
pF1KB4 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK
. :::::::::. . ::. ::..:..:. ::::.:::::.:.:::. ::.:::.:. .
NP_001 VTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT
::: : :...:...: : : .. : ..: . :.. : :::.::... . ...
NP_001 IHPIRIADGYEQAARVAIEHL-DKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMA
110 120 130 140 150 160
190 200 210 220 230
pF1KB4 KLAVEAVLRL----KGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQ-PKRIENA
..::.::: . . . ..: :.. :.:: : :. : .: ..:: .. : ::..:.:
NP_001 EIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB4 KILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQL
:: : . .. : : .. : :. ... ::::..: ...: . : : : .
NP_001 KIAILTCPFEPPKPKT-KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWG
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB4 IYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIG
. . ..:. .. :.. . .: .:..:::.:. :.. ::: :..:. .:
NP_001 FDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFG
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB4 --EDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCS
.::.. . ..: :: .::....:..::.:::::::::. . ..:.:.::::: .
NP_001 TTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAA
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB4 EMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAH-SEG
:. : ::.: :.. : : ::...: ::...: ...:.:.. . ....:: . .:
NP_001 EISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEM
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB4 NTTAGLD-MREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPD
: . :.: ...:: .:: . :.. :.: . :.. ...::..:.: :
NP_001 NPALGIDCLHKGT-NDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE
470 480 490 500 510 520
pF1KB4 HHPC
>>NP_036205 (OMIM: 256840,610150) T-complex protein 1 su (541 aa)
initn: 689 init1: 299 opt: 938 Z-score: 1163.2 bits: 225.0 E(85289): 4.7e-58
Smith-Waterman score: 938; 34.5% identity (69.9% similar) in 505 aa overlap (27-522:36-535)
10 20 30 40 50
pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSG
. ...: :... ....:::.:.::....
NP_036 TLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVD--
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 RDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESL
.:... :::::::::. . ::. ::..:..:. ::::.:::::.:.:::. ::.:::.:
NP_036 KDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 IAKKIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHK
. . ::: : :...:...: : : .. : ..: . :.. : :::.::... .
NP_036 LDRGIHPIRIADGYEQAARVAIEHL-DKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 DHFTKLAVEAVLRL----KGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQ-PKR
.....::.::: . . . ..: :.. :.:: : :. : .: ..:: .. : ::.
NP_036 RQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 IENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFI
.:.::: : . .. : : .. : :. ... ::::..: ...: . : : :
NP_036 VEDAKIAILTCPFEPPKPKT-KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB4 NRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEE
. . . ..:. .. :.. . .: .:..:::.:. :.. ::: :..:
NP_036 CQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQE
310 320 330 340 350 360
360 370 380 390 400
pF1KB4 VMIG--EDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYG
. .: .::.. . ..: :: .::....:..::.:::::::::. . ..:.:.:::
NP_036 ISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYG
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB4 GGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAH
:: .:. : ::.: :.. : : ::...: ::...: ...:.:.. . ....:: .
NP_036 GGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQ
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB4 -SEGNTTAGLD-MREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK
.: : . :.: ...:: .:: . :.. :.: . :.. ...::..:.: :
NP_036 VKEMNPALGIDCLHKGT-NDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESE
490 500 510 520 530 540
530
pF1KB4 RVPDHHPC
NP_036 E
>>NP_001293085 (OMIM: 256840,610150) T-complex protein 1 (503 aa)
initn: 689 init1: 299 opt: 937 Z-score: 1162.4 bits: 224.7 E(85289): 5.2e-58
Smith-Waterman score: 937; 34.7% identity (69.9% similar) in 502 aa overlap (30-522:1-497)
10 20 30 40 50 60
pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS
..: :... ....:::.:.::.... .:..
NP_001 MAAKAVANTMRTSLGPNGLDKMMVD--KDGD
10 20
70 80 90 100 110 120
pF1KB4 LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK
. :::::::::. . ::. ::..:..:. ::::.:::::.:.:::. ::.:::.:. .
NP_001 VTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRG
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB4 IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT
::: : :...:...: : : .. : ..: . :.. : :::.::... . ...
NP_001 IHPIRIADGYEQAARVAIEHL-DKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMA
90 100 110 120 130 140
190 200 210 220 230
pF1KB4 KLAVEAVLRL----KGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQ-PKRIENA
..::.::: . . . ..: :.. :.:: : :. : .: ..:: .. : ::..:.:
NP_001 EIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB4 KILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQL
:: : . .. : : .. : :. ... ::::..: ...: . : : : .
NP_001 KIAILTCPFEPPKPKT-KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWG
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB4 IYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIG
. . ..:. .. :.. . .: .:..:::.:. :.. ::: :..:. .:
NP_001 FDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFG
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB4 --EDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCS
.::.. . ..: :: .::....:..::.:::::::::. . ..:.:.::::: .
NP_001 TTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAA
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB4 EMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAH-SEG
:. : ::.: :.. : : ::...: ::...: ...:.:.. . ....:: . .:
NP_001 EISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEM
390 400 410 420 430 440
480 490 500 510 520 530
pF1KB4 NTTAGLD-MREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPD
: . :.: ...:: .:: . :.. :.: . :.. ...::..:.: :
NP_001 NPALGIDCLHKGT-NDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE
450 460 470 480 490 500
pF1KB4 HHPC
>>XP_011530781 (OMIM: 605140) PREDICTED: T-complex prote (499 aa)
initn: 846 init1: 455 opt: 934 Z-score: 1158.8 bits: 224.0 E(85289): 8.3e-58
Smith-Waterman score: 934; 35.3% identity (66.7% similar) in 487 aa overlap (48-529:1-483)
20 30 40 50 60 70
pF1KB4 EERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVD
:::.... :: . ..:::::::: . :
XP_011 MDKLIVD-GRGKAT-ISNDGATILKLLDVV
10 20
80 90 100 110 120 130
pF1KB4 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA
.::::.:::... :: ::::::::::.::::.:.... . . .::: :: ..: ::. :
XP_011 HPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLA
30 40 50 60 70 80
140 150 160 170 180 190
pF1KB4 REALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNL
. . :: . .:.:. :. : . : :.:::::....: :.:..:.::. : .:
XP_011 VNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQL
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB4 EAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIENAKILIANTGMDTDKIKIF
. : : : ::.: :: : : . : .. :::. .: :: . :. .. : .
XP_011 KMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKD
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB4 GSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAI
....:: .. : :: . . .:.:.: . : . ... : . : :. ..
XP_011 NAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCA
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB4 EHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACT
.. ..: .. :: : .. . :: :...::..:: .. :.: ...::
XP_011 GRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCT
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB4 IVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE
..:::...:...:.:::::::. .. ...:.. .: ::: :: ... . . . :::.
XP_011 FILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQ
330 340 350 360 370 380
440 450 460 470 480 490
pF1KB4 AVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILG
. . .:::::...: . ::::.:..... .::: :..:.: :.:. . :.:
XP_011 QLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAF
390 400 410 420 430 440
500 510 520 530
pF1KB4 ITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
. : .:. ..: .:.::: .:. ::. :: ::. :
XP_011 VWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAGRGRGRGRPH
450 460 470 480 490
>>NP_001159757 (OMIM: 605140) T-complex protein 1 subuni (499 aa)
initn: 846 init1: 455 opt: 934 Z-score: 1158.8 bits: 224.0 E(85289): 8.3e-58
Smith-Waterman score: 934; 35.3% identity (66.7% similar) in 487 aa overlap (48-529:1-483)
20 30 40 50 60 70
pF1KB4 EERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVD
:::.... :: . ..:::::::: . :
NP_001 MDKLIVD-GRGKAT-ISNDGATILKLLDVV
10 20
80 90 100 110 120 130
pF1KB4 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA
.::::.:::... :: ::::::::::.::::.:.... . . .::: :: ..: ::. :
NP_001 HPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLA
30 40 50 60 70 80
140 150 160 170 180 190
pF1KB4 REALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNL
. . :: . .:.:. :. : . : :.:::::....: :.:..:.::. : .:
NP_001 VNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQL
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB4 EAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIENAKILIANTGMDTDKIKIF
. : : : ::.: :: : : . : .. :::. .: :: . :. .. : .
NP_001 KMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKD
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB4 GSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAI
....:: .. : :: . . .:.:.: . : . ... : . : :. ..
NP_001 NAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCA
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB4 EHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACT
.. ..: .. :: : .. . :: :...::..:: .. :.: ...::
NP_001 GRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCT
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB4 IVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE
..:::...:...:.:::::::. .. ...:.. .: ::: :: ... . . . :::.
NP_001 FILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQ
330 340 350 360 370 380
440 450 460 470 480 490
pF1KB4 AVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILG
. . .:::::...: . ::::.:..... .::: :..:.: :.:. . :.:
NP_001 QLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAF
390 400 410 420 430 440
500 510 520 530
pF1KB4 ITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
. : .:. ..: .:.::: .:. ::. :: ::. :
NP_001 VWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAGRGRGRGRPH
450 460 470 480 490
>>XP_011530780 (OMIM: 605140) PREDICTED: T-complex prote (499 aa)
initn: 846 init1: 455 opt: 934 Z-score: 1158.8 bits: 224.0 E(85289): 8.3e-58
Smith-Waterman score: 934; 35.3% identity (66.7% similar) in 487 aa overlap (48-529:1-483)
20 30 40 50 60 70
pF1KB4 EERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVD
:::.... :: . ..:::::::: . :
XP_011 MDKLIVD-GRGKAT-ISNDGATILKLLDVV
10 20
80 90 100 110 120 130
pF1KB4 NPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAA
.::::.:::... :: ::::::::::.::::.:.... . . .::: :: ..: ::. :
XP_011 HPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLA
30 40 50 60 70 80
140 150 160 170 180 190
pF1KB4 REALLSSAVD-HGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNL
. . :: . .:.:. :. : . : :.:::::....: :.:..:.::. : .:
XP_011 VNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDDLLQL
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB4 EAIHIIKKLGGSLADSYLDEGFLLDKKIGVN----QPKRIENAKILIANTGMDTDKIKIF
. : : : ::.: :: : : . : .. :::. .: :: . :. .. : .
XP_011 KMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKD
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB4 GSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAI
....:: .. : :: . . .:.:.: . : . ... : . : :. ..
XP_011 NAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCA
210 220 230 240 250 260
320 330 340 350 360 370
pF1KB4 EHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACT
.. ..: .. :: : .. . :: :...::..:: .. :.: ...::
XP_011 GRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKTCT
270 280 290 300 310 320
380 390 400 410 420 430
pF1KB4 IVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKE
..:::...:...:.:::::::. .. ...:.. .: ::: :: ... . . . :::.
XP_011 FILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQ
330 340 350 360 370 380
440 450 460 470 480 490
pF1KB4 AVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILG
. . .:::::...: . ::::.:..... .::: :..:.: :.:. . :.:
XP_011 QLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAF
390 400 410 420 430 440
500 510 520 530
pF1KB4 ITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
. : .:. ..: .:.::: .:. ::. :: ::. :
XP_011 VWEPAMVRINALTAASEAACLIVSVDETIKN-PRSTVDAPTAAGRGRGRGRPH
450 460 470 480 490
>>NP_006421 (OMIM: 605142) T-complex protein 1 subunit d (539 aa)
initn: 738 init1: 345 opt: 843 Z-score: 1045.4 bits: 203.1 E(85289): 1.7e-51
Smith-Waterman score: 902; 32.2% identity (67.4% similar) in 522 aa overlap (14-521:23-536)
10 20 30 40 50
pF1KB4 MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKI
: :... :.... .: :..: ....::::::::.
NP_006 MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 LLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLR
. .. :.. .:::::::::.. : .:::..::..:..:: :.:::::::...:. ::
NP_006 IQDGKGDVT--ITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLD
70 80 90 100 110
120 130 140 150 160
pF1KB4 EAESLIAKKIHPQTIIAGWREATKAAREAL--LSSAVDHGSDEVKFRQDLMNIAGTTLSS
.:. : ::: : ....: . . : : .: :. :: :. :.: : :.:.:
NP_006 SCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVEL-SD----RETLLNSATTSLNS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 KLLTHHKDHFTKLAVEAVLRL-----KGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKI
:....... .. ..:.::... : .:. :.:.:::::.. : : ::..: .:.
NP_006 KVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB4 GVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILK
. . :.:.::: . . ... : . ... :.. :.. .. . :. . . :..: :
NP_006 SNSGITRVEKAKIGLIQFCLSAPKTDM-DNQIVVSDYAQMDRVLREERAYILNLVKQIKK
240 250 260 270 280 290
290 300 310 320 330
pF1KB4 HGINCF-----INRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPE
: : . : :. . . .... .:.:. . .: . . : . .. .:.
NP_006 TGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFT
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB4 LVKLGSCKLIEEVMI-GEDKLIHFSGVAL-GEACTIVLRGATQQILDEAERSLHDALCVL
::: .: ::: . : ::....: : :.. :::.::... ...:::::.::::::.
NP_006 ADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVI
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB4 AQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYD
:: . ::: :. .: .:. . : :. ....: :....:. .:.::: .
NP_006 RCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLN
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB4 SADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRV
. :..:: :..:. :::...:.: :... ... . :. ..: :.:... ::..
NP_006 PISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKI
480 490 500 510 520 530
520 530
pF1KB4 DNIIKAAPRKRVPDHHPC
:...
NP_006 DDVVNTR
535 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:40:58 2016 done: Thu Nov 3 15:40:59 2016
Total Scan time: 9.020 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]