FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4987, 471 aa 1>>>pF1KB4987 471 - 471 aa - 471 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9114+/-0.000378; mu= 15.0552+/- 0.024 mean_var=73.5389+/-14.696, 0's: 0 Z-trim(113.5): 26 B-trim: 0 in 0/53 Lambda= 0.149560 statistics sampled from 22776 (22802) to 22776 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.267), width: 16 Scan time: 9.250 The best scores are: opt bits E(85289) XP_016877117 (OMIM: 191050) PREDICTED: tryptophan- ( 471) 3153 689.7 4.5e-198 XP_016877116 (OMIM: 191050) PREDICTED: tryptophan- ( 471) 3153 689.7 4.5e-198 XP_005268101 (OMIM: 191050) PREDICTED: tryptophan- ( 471) 3153 689.7 4.5e-198 XP_011535437 (OMIM: 191050) PREDICTED: tryptophan- ( 471) 3153 689.7 4.5e-198 NP_004175 (OMIM: 191050) tryptophan--tRNA ligase, ( 471) 3153 689.7 4.5e-198 XP_016877118 (OMIM: 191050) PREDICTED: tryptophan- ( 471) 3153 689.7 4.5e-198 NP_776049 (OMIM: 191050) tryptophan--tRNA ligase, ( 471) 3153 689.7 4.5e-198 XP_011535435 (OMIM: 191050) PREDICTED: tryptophan- ( 471) 3153 689.7 4.5e-198 XP_006720312 (OMIM: 191050) PREDICTED: tryptophan- ( 471) 3153 689.7 4.5e-198 NP_998810 (OMIM: 191050) tryptophan--tRNA ligase, ( 430) 2904 636.0 6.2e-182 NP_998811 (OMIM: 191050) tryptophan--tRNA ligase, ( 430) 2904 636.0 6.2e-182 XP_011535438 (OMIM: 191050) PREDICTED: tryptophan- ( 430) 2904 636.0 6.2e-182 XP_016856103 (OMIM: 138295) PREDICTED: bifunctiona ( 986) 188 50.1 3.3e-05 NP_004437 (OMIM: 138295) bifunctional glutamate/pr (1512) 188 50.2 4.8e-05 >>XP_016877117 (OMIM: 191050) PREDICTED: tryptophan--tRN (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>XP_016877116 (OMIM: 191050) PREDICTED: tryptophan--tRN (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>XP_005268101 (OMIM: 191050) PREDICTED: tryptophan--tRN (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>XP_011535437 (OMIM: 191050) PREDICTED: tryptophan--tRN (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>NP_004175 (OMIM: 191050) tryptophan--tRNA ligase, cyto (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>XP_016877118 (OMIM: 191050) PREDICTED: tryptophan--tRN (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>NP_776049 (OMIM: 191050) tryptophan--tRNA ligase, cyto (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_776 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_776 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_776 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_776 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_776 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_776 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_776 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_776 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>XP_011535435 (OMIM: 191050) PREDICTED: tryptophan--tRN (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>XP_006720312 (OMIM: 191050) PREDICTED: tryptophan--tRN (471 aa) initn: 3153 init1: 3153 opt: 3153 Z-score: 3677.1 bits: 689.7 E(85289): 4.5e-198 Smith-Waterman score: 3153; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 430 440 450 460 470 >>NP_998810 (OMIM: 191050) tryptophan--tRNA ligase, cyto (430 aa) initn: 2904 init1: 2904 opt: 2904 Z-score: 3387.3 bits: 636.0 E(85289): 6.2e-182 Smith-Waterman score: 2904; 100.0% identity (100.0% similar) in 430 aa overlap (42-471:1-430) 20 30 40 50 60 70 pF1KB4 LFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTS :::::::::::::::::::::::::::::: NP_998 MLVSLKMSYKAAAGEDYKADCPPGNPAPTS 10 20 30 80 90 100 110 120 130 pF1KB4 NHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 NHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHF 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 LRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 LRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPL 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 VIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 VIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 VKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 VKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAI 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 DQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 DQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTK 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 VNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_998 VNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELK 340 350 360 370 380 390 440 450 460 470 pF1KB4 KALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ :::::::::::::::::::::::::::::::::::::::: NP_998 KALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 400 410 420 430 471 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:10:44 2016 done: Sat Nov 5 06:10:45 2016 Total Scan time: 9.250 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]