FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4988, 253 aa 1>>>pF1KB4988 253 - 253 aa - 253 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.3922+/-0.000422; mu= 19.6534+/- 0.026 mean_var=61.9705+/-12.547, 0's: 0 Z-trim(111.1): 97 B-trim: 586 in 1/48 Lambda= 0.162923 statistics sampled from 19532 (19635) to 19532 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.585), E-opt: 0.2 (0.23), width: 16 Scan time: 6.300 The best scores are: opt bits E(85289) NP_005715 (OMIM: 613134) tetraspanin-3 isoform 1 [ ( 253) 1703 408.9 4.5e-114 XP_016877346 (OMIM: 613134) PREDICTED: tetraspanin ( 214) 1294 312.7 3.5e-85 NP_001161884 (OMIM: 613134) tetraspanin-3 isoform ( 189) 1133 274.8 7.9e-74 NP_944492 (OMIM: 613134) tetraspanin-3 isoform 2 [ ( 228) 993 241.9 7.2e-64 NP_001034579 (OMIM: 179620,602243,609057) CD151 an ( 253) 460 116.7 4e-26 NP_620599 (OMIM: 179620,602243,609057) CD151 antig ( 253) 460 116.7 4e-26 NP_620598 (OMIM: 179620,602243,609057) CD151 antig ( 253) 460 116.7 4e-26 NP_004348 (OMIM: 179620,602243,609057) CD151 antig ( 253) 460 116.7 4e-26 NP_004606 (OMIM: 300096,300210) tetraspanin-7 [Hom ( 249) 456 115.8 7.6e-26 NP_003261 (OMIM: 300191) tetraspanin-6 isoform a [ ( 245) 441 112.2 8.7e-25 XP_005253159 (OMIM: 602644) PREDICTED: tetraspanin ( 238) 414 105.9 6.9e-23 NP_001020407 (OMIM: 602644) tetraspanin-4 isoform ( 238) 414 105.9 6.9e-23 NP_001020408 (OMIM: 602644) tetraspanin-4 isoform ( 238) 414 105.9 6.9e-23 NP_003262 (OMIM: 602644) tetraspanin-4 isoform a [ ( 238) 414 105.9 6.9e-23 NP_001020406 (OMIM: 602644) tetraspanin-4 isoform ( 238) 414 105.9 6.9e-23 NP_001020405 (OMIM: 602644) tetraspanin-4 isoform ( 238) 414 105.9 6.9e-23 NP_001020409 (OMIM: 602644) tetraspanin-4 isoform ( 238) 414 105.9 6.9e-23 NP_001244318 (OMIM: 155740) CD63 antigen isoform A ( 238) 413 105.6 8.2e-23 NP_001771 (OMIM: 155740) CD63 antigen isoform A [H ( 238) 413 105.6 8.2e-23 NP_001254627 (OMIM: 155740) CD63 antigen isoform A ( 238) 413 105.6 8.2e-23 NP_001244319 (OMIM: 155740) CD63 antigen isoform A ( 238) 413 105.6 8.2e-23 NP_001244320 (OMIM: 155740) CD63 antigen isoform A ( 238) 413 105.6 8.2e-23 NP_001244321 (OMIM: 155740) CD63 antigen isoform C ( 215) 409 104.7 1.5e-22 NP_006666 (OMIM: 613137) tetraspanin-9 [Homo sapie ( 239) 382 98.4 1.3e-20 NP_001161792 (OMIM: 613137) tetraspanin-9 [Homo sa ( 239) 382 98.4 1.3e-20 XP_011518638 (OMIM: 602644) PREDICTED: tetraspanin ( 269) 380 97.9 1.9e-20 NP_005718 (OMIM: 613170) tetraspanin-1 [Homo sapie ( 241) 356 92.2 8.9e-19 XP_006719646 (OMIM: 600769) PREDICTED: tetraspanin ( 237) 353 91.5 1.4e-18 NP_004607 (OMIM: 600769) tetraspanin-8 [Homo sapie ( 237) 353 91.5 1.4e-18 XP_016875402 (OMIM: 600769) PREDICTED: tetraspanin ( 237) 353 91.5 1.4e-18 NP_001020410 (OMIM: 602644) tetraspanin-4 isoform ( 174) 338 87.9 1.3e-17 XP_011518643 (OMIM: 602644) PREDICTED: tetraspanin ( 174) 338 87.9 1.3e-17 XP_011518639 (OMIM: 602644) PREDICTED: tetraspanin ( 174) 338 87.9 1.3e-17 XP_011518640 (OMIM: 602644) PREDICTED: tetraspanin ( 174) 338 87.9 1.3e-17 XP_011518642 (OMIM: 602644) PREDICTED: tetraspanin ( 174) 338 87.9 1.3e-17 XP_011538762 (OMIM: 613170) PREDICTED: tetraspanin ( 258) 339 88.3 1.5e-17 NP_001035122 (OMIM: 151525) leukocyte surface anti ( 219) 329 85.9 6.7e-17 NP_000551 (OMIM: 151525) leukocyte surface antigen ( 219) 329 85.9 6.7e-17 XP_011529320 (OMIM: 300191) PREDICTED: tetraspanin ( 157) 305 80.1 2.7e-15 NP_001265669 (OMIM: 300191) tetraspanin-6 isoform ( 157) 305 80.1 2.7e-15 NP_001265670 (OMIM: 300191) tetraspanin-6 isoform ( 157) 305 80.1 2.7e-15 NP_848657 (OMIM: 610120) tetraspanin-33 [Homo sapi ( 283) 306 80.6 3.4e-15 XP_006716023 (OMIM: 610120) PREDICTED: tetraspanin ( 282) 302 79.6 6.6e-15 XP_006718286 (OMIM: 176807,600623) PREDICTED: CD82 ( 267) 297 78.4 1.4e-14 NP_002222 (OMIM: 176807,600623) CD82 antigen isofo ( 267) 297 78.4 1.4e-14 XP_011519215 (OMIM: 613137) PREDICTED: tetraspanin ( 175) 292 77.1 2.4e-14 XP_011519214 (OMIM: 613137) PREDICTED: tetraspanin ( 175) 292 77.1 2.4e-14 NP_001244329 (OMIM: 155740) CD63 antigen isoform D ( 156) 289 76.3 3.6e-14 NP_001244330 (OMIM: 155740) CD63 antigen isoform D ( 156) 289 76.3 3.6e-14 NP_001765 (OMIM: 151523) leukocyte antigen CD37 is ( 281) 285 75.6 1e-13 >>NP_005715 (OMIM: 613134) tetraspanin-3 isoform 1 [Homo (253 aa) initn: 1703 init1: 1703 opt: 1703 Z-score: 2168.9 bits: 408.9 E(85289): 4.5e-114 Smith-Waterman score: 1703; 100.0% identity (100.0% similar) in 253 aa overlap (1-253:1-253) 10 20 30 40 50 60 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 190 200 210 220 230 240 250 pF1KB4 PAYELLITGGTYA ::::::::::::: NP_005 PAYELLITGGTYA 250 >>XP_016877346 (OMIM: 613134) PREDICTED: tetraspanin-3 i (214 aa) initn: 1294 init1: 1294 opt: 1294 Z-score: 1650.3 bits: 312.7 E(85289): 3.5e-85 Smith-Waterman score: 1294; 100.0% identity (100.0% similar) in 192 aa overlap (62-253:23-214) 40 50 60 70 80 90 pF1KB4 AYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILL :::::::::::::::::::::::::::::: XP_016 MWEPMSSSLMMTMTTSLKMCTRALLFIIGLIGCCATIRESRCGLATFVIILL 10 20 30 40 50 100 110 120 130 140 150 pF1KB4 LVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIH 60 70 80 90 100 110 160 170 180 190 200 210 pF1KB4 NYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMH 120 130 140 150 160 170 220 230 240 250 pF1KB4 VIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA :::::::::::::::::::::::::::::::::::::::::: XP_016 VIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA 180 190 200 210 >>NP_001161884 (OMIM: 613134) tetraspanin-3 isoform 3 [H (189 aa) initn: 1261 init1: 1133 opt: 1133 Z-score: 1446.5 bits: 274.8 E(85289): 7.9e-74 Smith-Waterman score: 1137; 74.7% identity (74.7% similar) in 253 aa overlap (1-253:1-189) 10 20 30 40 50 60 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV ::::::::::::::::::::: NP_001 MGQCGITSSKTVLVFLNLIFW--------------------------------------- 10 20 70 80 90 100 110 120 pF1KB4 GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ ::::::::::::::::::::::::::::::::::: NP_001 -------------------------FVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 30 40 50 130 140 150 160 170 180 pF1KB4 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 60 70 80 90 100 110 190 200 210 220 230 240 pF1KB4 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 120 130 140 150 160 170 250 pF1KB4 PAYELLITGGTYA ::::::::::::: NP_001 PAYELLITGGTYA 180 >>NP_944492 (OMIM: 613134) tetraspanin-3 isoform 2 [Homo (228 aa) initn: 993 init1: 993 opt: 993 Z-score: 1267.6 bits: 241.9 E(85289): 7.2e-64 Smith-Waterman score: 1499; 90.1% identity (90.1% similar) in 253 aa overlap (1-253:1-228) 10 20 30 40 50 60 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_944 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ ::::::::::::::::::::::::: :::::::::: NP_944 GALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSIQ 70 80 90 130 140 150 160 170 180 pF1KB4 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_944 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_944 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 160 170 180 190 200 210 250 pF1KB4 PAYELLITGGTYA ::::::::::::: NP_944 PAYELLITGGTYA 220 >>NP_001034579 (OMIM: 179620,602243,609057) CD151 antige (253 aa) initn: 403 init1: 233 opt: 460 Z-score: 590.0 bits: 116.7 E(85289): 4e-26 Smith-Waterman score: 460; 29.9% identity (67.9% similar) in 234 aa overlap (4-231:11-242) 10 20 30 40 50 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP :: . : .: : :: :. . :: ... .:: .. . : NP_001 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLAT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 AVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVEN : .....:..... :..:::::..: : : . :.::..:. :... .:.:.: .... NP_001 AYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 EVDRSIQKVY-KTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSV :. .... .. : :. . .:.. :.: .:...:::: .: .::....:.. :. .. : NP_001 ELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVV 130 140 150 160 170 180 180 190 200 210 220 pF1KB4 PLSCCRETASNCNGSLAHPSDLYAE--GCEALVVKKLQEIMMHVIWAA-LAFAAIQLLGM : :::. ... : :. : :..: :: . . .:: ..:: :. ...: .:..:: NP_001 PDSCCKTVVALC-GQRDHASNIYKVEGGCITKLETFIQE-HLRVIGAVGIGIACVQVFGM 190 200 210 220 230 230 240 250 pF1KB4 LCACIVLCRRSRDPAYELLITGGTYA . .: NP_001 IFTCCLYRSLKLEHY 240 250 >>NP_620599 (OMIM: 179620,602243,609057) CD151 antigen [ (253 aa) initn: 403 init1: 233 opt: 460 Z-score: 590.0 bits: 116.7 E(85289): 4e-26 Smith-Waterman score: 460; 29.9% identity (67.9% similar) in 234 aa overlap (4-231:11-242) 10 20 30 40 50 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP :: . : .: : :: :. . :: ... .:: .. . : NP_620 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLAT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 AVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVEN : .....:..... :..:::::..: : : . :.::..:. :... .:.:.: .... NP_620 AYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 EVDRSIQKVY-KTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSV :. .... .. : :. . .:.. :.: .:...:::: .: .::....:.. :. .. : NP_620 ELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVV 130 140 150 160 170 180 180 190 200 210 220 pF1KB4 PLSCCRETASNCNGSLAHPSDLYAE--GCEALVVKKLQEIMMHVIWAA-LAFAAIQLLGM : :::. ... : :. : :..: :: . . .:: ..:: :. ...: .:..:: NP_620 PDSCCKTVVALC-GQRDHASNIYKVEGGCITKLETFIQE-HLRVIGAVGIGIACVQVFGM 190 200 210 220 230 230 240 250 pF1KB4 LCACIVLCRRSRDPAYELLITGGTYA . .: NP_620 IFTCCLYRSLKLEHY 240 250 >>NP_620598 (OMIM: 179620,602243,609057) CD151 antigen [ (253 aa) initn: 403 init1: 233 opt: 460 Z-score: 590.0 bits: 116.7 E(85289): 4e-26 Smith-Waterman score: 460; 29.9% identity (67.9% similar) in 234 aa overlap (4-231:11-242) 10 20 30 40 50 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP :: . : .: : :: :. . :: ... .:: .. . : NP_620 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLAT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 AVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVEN : .....:..... :..:::::..: : : . :.::..:. :... .:.:.: .... NP_620 AYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 EVDRSIQKVY-KTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSV :. .... .. : :. . .:.. :.: .:...:::: .: .::....:.. :. .. : NP_620 ELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVV 130 140 150 160 170 180 180 190 200 210 220 pF1KB4 PLSCCRETASNCNGSLAHPSDLYAE--GCEALVVKKLQEIMMHVIWAA-LAFAAIQLLGM : :::. ... : :. : :..: :: . . .:: ..:: :. ...: .:..:: NP_620 PDSCCKTVVALC-GQRDHASNIYKVEGGCITKLETFIQE-HLRVIGAVGIGIACVQVFGM 190 200 210 220 230 230 240 250 pF1KB4 LCACIVLCRRSRDPAYELLITGGTYA . .: NP_620 IFTCCLYRSLKLEHY 240 250 >>NP_004348 (OMIM: 179620,602243,609057) CD151 antigen [ (253 aa) initn: 403 init1: 233 opt: 460 Z-score: 590.0 bits: 116.7 E(85289): 4e-26 Smith-Waterman score: 460; 29.9% identity (67.9% similar) in 234 aa overlap (4-231:11-242) 10 20 30 40 50 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP :: . : .: : :: :. . :: ... .:: .. . : NP_004 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLAT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 AVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVEN : .....:..... :..:::::..: : : . :.::..:. :... .:.:.: .... NP_004 AYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 EVDRSIQKVY-KTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSV :. .... .. : :. . .:.. :.: .:...:::: .: .::....:.. :. .. : NP_004 ELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVV 130 140 150 160 170 180 180 190 200 210 220 pF1KB4 PLSCCRETASNCNGSLAHPSDLYAE--GCEALVVKKLQEIMMHVIWAA-LAFAAIQLLGM : :::. ... : :. : :..: :: . . .:: ..:: :. ...: .:..:: NP_004 PDSCCKTVVALC-GQRDHASNIYKVEGGCITKLETFIQE-HLRVIGAVGIGIACVQVFGM 190 200 210 220 230 230 240 250 pF1KB4 LCACIVLCRRSRDPAYELLITGGTYA . .: NP_004 IFTCCLYRSLKLEHY 240 250 >>NP_004606 (OMIM: 300096,300210) tetraspanin-7 [Homo sa (249 aa) initn: 422 init1: 145 opt: 456 Z-score: 585.0 bits: 115.8 E(85289): 7.6e-26 Smith-Waterman score: 456; 34.1% identity (63.8% similar) in 246 aa overlap (6-246:12-249) 10 20 30 40 50 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPA :: ::.:.. ...:: .. :: ::.. .: : .. . : : NP_004 MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP- 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 VVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENE :.:..:. . ..::.:: :: : : : ....: :::..:.:. . :.:.: .... NP_004 YVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 VDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSC :. ...::::. : :::.:.:::.: :::..::..: .. .: : ...: :: NP_004 FLRTYTDAMQTYNGN--DERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLE---HGIPPSC 120 130 140 150 160 170 180 190 200 210 220 pF1KB4 CRETASNCNGSLAHPSDLYA-----EGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLC : . ..:: . : . : .:: ::.. .. : . .:...: ::.::: NP_004 CMNE-TDCNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLL 180 190 200 210 220 230 230 240 250 pF1KB4 ACIVLCRRSRDPAYELLITGGTYA :: : : ::.. NP_004 AC-CLSRFITANQYEMV 240 >>NP_003261 (OMIM: 300191) tetraspanin-6 isoform a [Homo (245 aa) initn: 376 init1: 176 opt: 441 Z-score: 566.0 bits: 112.2 E(85289): 8.7e-25 Smith-Waterman score: 441; 32.2% identity (64.5% similar) in 242 aa overlap (6-246:14-245) 10 20 30 40 50 pF1KB4 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLI :: :.::.. ..::: .. :: :: . .. ..: .... : . NP_003 MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 PAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVE : :.::.:......: .:: :: : : : ....: :::..:.:....:.:.: ... NP_003 P-FVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIK 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 NEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPL : . .:. : ::.:. : :.:.: .: :::::. .: :: .:....: .. : NP_003 NSFKNNYEKALKQYNSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSE---KGFPK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 SCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCA-C :::. .:. . . . ::: :. .. : : ... : .::.:.. : : NP_003 SCCK--LEDCTPQ-RDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYC 180 190 200 210 220 230 240 250 pF1KB4 IVLCRRSRDPAYELLITGGTYA : : . ::.. NP_003 --LSRAITNNQYEIV 240 253 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:11:20 2016 done: Sat Nov 5 06:11:21 2016 Total Scan time: 6.300 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]