FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4992, 281 aa 1>>>pF1KB4992 281 - 281 aa - 281 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9590+/-0.000689; mu= 13.4749+/- 0.042 mean_var=87.0540+/-17.082, 0's: 0 Z-trim(111.9): 7 B-trim: 0 in 0/51 Lambda= 0.137461 statistics sampled from 12720 (12727) to 12720 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.391), width: 16 Scan time: 2.210 The best scores are: opt bits E(32554) CCDS1731.1 MAPRE3 gene_id:22924|Hs108|chr2 ( 281) 1909 387.7 5e-108 CCDS45851.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 284) 1142 235.6 3.1e-62 CCDS45850.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 315) 1142 235.6 3.4e-62 CCDS11910.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 327) 1142 235.6 3.5e-62 CCDS58619.1 MAPRE2 gene_id:10982|Hs108|chr18 ( 274) 932 193.9 1e-49 CCDS13208.1 MAPRE1 gene_id:22919|Hs108|chr20 ( 268) 885 184.6 6.5e-47 >>CCDS1731.1 MAPRE3 gene_id:22924|Hs108|chr2 (281 aa) initn: 1909 init1: 1909 opt: 1909 Z-score: 2052.9 bits: 387.7 E(32554): 5e-108 Smith-Waterman score: 1909; 100.0% identity (100.0% similar) in 281 aa overlap (1-281:1-281) 10 20 30 40 50 60 pF1KB4 MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 VKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 GKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 GKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PCILRKNPPSARNGGHETDAQILELNQQLVDLKLTVDGLEKERDFYFSKLRDIELICQEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 PCILRKNPPSARNGGHETDAQILELNQQLVDLKLTVDGLEKERDFYFSKLRDIELICQEH 190 200 210 220 230 240 250 260 270 280 pF1KB4 ESENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY ::::::::::::::::::::::::::::::::::::::::: CCDS17 ESENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY 250 260 270 280 >>CCDS45851.1 MAPRE2 gene_id:10982|Hs108|chr18 (284 aa) initn: 1197 init1: 880 opt: 1142 Z-score: 1230.8 bits: 235.6 E(32554): 3.1e-62 Smith-Waterman score: 1142; 59.2% identity (83.0% similar) in 289 aa overlap (1-281:1-284) 10 20 30 40 50 60 pF1KB4 MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRK :::::::::.:.:..::::..::::: . :::::.::::::::::::::::::::. :.: CCDS45 MAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYD ::::::::::::::::.:::.::.:.:::.:::::::::.::::..::::::::.::::: CCDS45 VKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYD 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 GKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQ----RTSPTGPKNMQTSGRLS ::.:.:. ::::::. :::.::.:::: :: . : ..::.. : .: .: : CCDS45 GKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAA-KPGSTPSRPS 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 NVAPPCILRKNPPSARNGGHETDAQILELNQQLVDLKLTVDGLEKERDFYFSKLRDIELI .. .. :: .. .. ..:...::.:. .:::...:.::::::::.:::.:::. CCDS45 SAKRA----SSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELL 180 190 200 210 220 230 240 250 260 270 280 pF1KB4 CQEHESENSPVISGIIGILYATEEGFAPPEDDEIEE--HQQE--DQDEY :::: .::. ... .. ::::.:: . :. : :: :.:. .:.:: CCDS45 CQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY 240 250 260 270 280 >>CCDS45850.1 MAPRE2 gene_id:10982|Hs108|chr18 (315 aa) initn: 1197 init1: 880 opt: 1142 Z-score: 1230.1 bits: 235.6 E(32554): 3.4e-62 Smith-Waterman score: 1142; 59.2% identity (83.0% similar) in 289 aa overlap (1-281:32-315) 10 20 30 pF1KB4 MAVNVYSTSVTSENLSRHDMLAWVNDSLHL :::::::::.:.:..::::..::::: . : CCDS45 KQNRDQKCPVSQRNSSFQQPGRKPGCSSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 NYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKI ::::.::::::::::::::::::::. :.:::::::::::::::::.:::.::.:.:::. CCDS45 NYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 IPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPGDQIFNKSK :::::::::.::::..::::::::.:::::::.:.:. ::::::. :::.::.:::: : CCDS45 IPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPK 130 140 150 160 170 180 160 170 180 190 200 pF1KB4 KLIGTAVPQ----RTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGGHETDAQILELN : . : ..::.. : .: .: :.. .. :: .. .. ..:...:: CCDS45 KSHHANSPTAGAAKSSPAA-KPGSTPSRPSSAKRA----SSSGSASKSDKDLETQVIQLN 190 200 210 220 230 210 220 230 240 250 260 pF1KB4 QQLVDLKLTVDGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPE .:. .:::...:.::::::::.:::.:::.:::: .::. ... .. ::::.:: . : CCDS45 EQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTE 240 250 260 270 280 290 270 280 pF1KB4 DDEIEE--HQQE--DQDEY . : :: :.:. .:.:: CCDS45 EPEAEEQAHEQQPPQQEEY 300 310 >>CCDS11910.1 MAPRE2 gene_id:10982|Hs108|chr18 (327 aa) initn: 1197 init1: 880 opt: 1142 Z-score: 1229.9 bits: 235.6 E(32554): 3.5e-62 Smith-Waterman score: 1142; 59.2% identity (83.0% similar) in 289 aa overlap (1-281:44-327) 10 20 30 pF1KB4 MAVNVYSTSVTSENLSRHDMLAWVNDSLHL :::::::::.:.:..::::..::::: . : CCDS11 NNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB4 NYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKI ::::.::::::::::::::::::::. :.:::::::::::::::::.:::.::.:.:::. CCDS11 NYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKV 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB4 IPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPGDQIFNKSK :::::::::.::::..::::::::.:::::::.:.:. ::::::. :::.::.:::: : CCDS11 IPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPK 140 150 160 170 180 190 160 170 180 190 200 pF1KB4 KLIGTAVPQ----RTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGGHETDAQILELN : . : ..::.. : .: .: :.. .. :: .. .. ..:...:: CCDS11 KSHHANSPTAGAAKSSPAA-KPGSTPSRPSSAKRA----SSSGSASKSDKDLETQVIQLN 200 210 220 230 240 210 220 230 240 250 260 pF1KB4 QQLVDLKLTVDGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPE .:. .:::...:.::::::::.:::.:::.:::: .::. ... .. ::::.:: . : CCDS11 EQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTE 250 260 270 280 290 300 270 280 pF1KB4 DDEIEE--HQQE--DQDEY . : :: :.:. .:.:: CCDS11 EPEAEEQAHEQQPPQQEEY 310 320 >>CCDS58619.1 MAPRE2 gene_id:10982|Hs108|chr18 (274 aa) initn: 987 init1: 670 opt: 932 Z-score: 1005.9 bits: 193.9 E(32554): 1e-49 Smith-Waterman score: 932; 56.4% identity (81.2% similar) in 250 aa overlap (40-281:30-274) 10 20 30 40 50 60 pF1KB4 VTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEH .:::::::::::::::. :.:::::::::: CCDS58 MARTTTTSSRIITGPSFLSGSTQCAGSVPTGAAYCQFMDMLFPGCISLKKVKFQAKLEH 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLA :::::::.:::.::.:.:::.:::::::::.::::..::::::::.:::::::.:.:. : CCDS58 EYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 RQGQDVAPPPNPGDQIFNKSKKLIGTAVPQ----RTSPTGPKNMQTSGRLSNVAPPCILR :::::. :::.::.:::: :: . : ..::.. : .: .: :.. CCDS58 RQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAA-KPGSTPSRPSSAKRA---- 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 KNPPSARNGGHETDAQILELNQQLVDLKLTVDGLEKERDFYFSKLRDIELICQEHESENS .. :: .. .. ..:...::.:. .:::...:.::::::::.:::.:::.:::: .::. CCDS58 SSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQEND 180 190 200 210 220 230 250 260 270 280 pF1KB4 PVISGIIGILYATEEGFAPPEDDEIEE--HQQE--DQDEY ... .. ::::.:: . :. : :: :.:. .:.:: CCDS58 DLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY 240 250 260 270 >>CCDS13208.1 MAPRE1 gene_id:22919|Hs108|chr20 (268 aa) initn: 1157 init1: 838 opt: 885 Z-score: 955.7 bits: 184.6 E(32554): 6.5e-47 Smith-Waterman score: 1159; 65.4% identity (81.6% similar) in 283 aa overlap (1-281:1-268) 10 20 30 40 50 60 pF1KB4 MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRK ::::::::::::.::::::::::.:.::.:: :::::::::::::::::::::: . :.: CCDS13 MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYD ::::::::::::.:::.:::.::.:::::::::.:::::::::::::.:::::::::::: CCDS13 VKFQAKLEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYD 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 GKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLI--GTAVPQRTSPTGPKNMQTSGRLSNV ::::.:. :::::..: :. .:: :: . ..:.::: : . : .. . CCDS13 GKDYDPVAARQGQETAVAPSLVAPALNKPKKPLTSSSAAPQR-----PISTQRTAAAPK- 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 APPCILRKNPPSARNGGHETDAQILELNQQLVDLKLTVDGLEKERDFYFSKLRDIELICQ : : ..:::: .. :: : . :: ::. :::::. :::::::::.:::.:::::: CCDS13 AGPGVVRKNP-GVGNG----DDEAAELMQQVNVLKLTVEDLEKERDFYFGKLRNIELICQ 180 190 200 210 220 240 250 260 270 280 pF1KB4 EHESENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY :.:.::.::.. :. :::::.:::. :. : ::.:.:: CCDS13 ENEGENDPVLQRIVDILYATDEGFVIPD----EGGPQEEQEEY 230 240 250 260 281 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:12:32 2016 done: Sat Nov 5 06:12:32 2016 Total Scan time: 2.210 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]