FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5004, 382 aa 1>>>pF1KB5004 382 - 382 aa - 382 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1229+/-0.000771; mu= 17.1385+/- 0.046 mean_var=62.4287+/-12.851, 0's: 0 Z-trim(107.9): 56 B-trim: 437 in 1/48 Lambda= 0.162324 statistics sampled from 9825 (9881) to 9825 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.304), width: 16 Scan time: 2.750 The best scores are: opt bits E(32554) CCDS4880.1 KLHDC3 gene_id:116138|Hs108|chr6 ( 382) 2731 648.1 3.8e-186 CCDS33606.1 LZTR1 gene_id:8216|Hs108|chr22 ( 840) 280 74.3 4.4e-13 CCDS10963.1 KLHDC4 gene_id:54758|Hs108|chr16 ( 520) 259 69.3 9e-12 CCDS55341.1 RABEPK gene_id:10244|Hs108|chr9 ( 321) 256 68.5 9.8e-12 CCDS6862.1 RABEPK gene_id:10244|Hs108|chr9 ( 372) 247 66.4 4.8e-11 >>CCDS4880.1 KLHDC3 gene_id:116138|Hs108|chr6 (382 aa) initn: 2731 init1: 2731 opt: 2731 Z-score: 3455.5 bits: 648.1 E(32554): 3.8e-186 Smith-Waterman score: 2731; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382) 10 20 30 40 50 60 pF1KB5 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 PVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 SGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 DFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 SHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 DKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDI 310 320 330 340 350 360 370 380 pF1KB5 RWELNAMTTNSNISRPIVSSHG :::::::::::::::::::::: CCDS48 RWELNAMTTNSNISRPIVSSHG 370 380 >>CCDS33606.1 LZTR1 gene_id:8216|Hs108|chr22 (840 aa) initn: 281 init1: 128 opt: 280 Z-score: 348.3 bits: 74.3 E(32554): 4.4e-13 Smith-Waterman score: 301; 29.5% identity (55.6% similar) in 241 aa overlap (113-336:52-278) 90 100 110 120 130 140 pF1KB5 VLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFT-PRVSGTVPGARDGHSACVLGKIMY :.: : . : . :. :.. . .: CCDS33 SKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIY 30 40 50 60 70 80 150 160 170 180 190 200 pF1KB5 IFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSATMLGSHMYVFGGRADR .::: ... . ::. ..:.. .: : :.: : :::.. :: :.:::: . CCDS33 VFGG--DNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYT-- 90 100 110 120 130 210 220 230 240 250 pF1KB5 FGPFHSNNEIYCNRIRVFDTR--TEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGY-- : ..::... :. .:. . : : . :: .: .:.: :. .:.::.:: CCDS33 -GDIYSNSNLK-NKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDG 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB5 NARLNRHFHDLWK--FNPVSFT-WKKIEPKGKGPCPRRRQCC----CIVGDKIVLFGGTS ::::: :.: .. .: :... .:. : : .:: . ::. .:.: : CCDS33 NARLN----DMWTIGLQDRELTCWEEVAQSGEIP-P---SCCNFPVAVCRDKMFVFSGQS 200 210 220 230 240 320 330 340 350 360 pF1KB5 PSPEEGLGDEFDLIDHS-----DLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELN . . .:.. :.. :.: :: CCDS33 GAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTL 250 260 270 280 290 300 370 380 pF1KB5 AMTTNSNISRPIVSSHG CCDS33 PNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKKSRDVFGL 310 320 330 340 350 360 >>CCDS10963.1 KLHDC4 gene_id:54758|Hs108|chr16 (520 aa) initn: 169 init1: 112 opt: 259 Z-score: 324.9 bits: 69.3 E(32554): 9e-12 Smith-Waterman score: 259; 28.6% identity (57.6% similar) in 203 aa overlap (140-332:78-271) 110 120 130 140 150 160 pF1KB5 VNTHKWFTPRVSGTVPGARDGHSACVLGKIMYIFGG--YEQQADCFSNDIHKLDTSTMTW . .::: .. : . :... .: :: CCDS10 AKRTQTVELPCPPPSPRLNASLSVHPEKDELILFGGEYFNGQKTFLYNELYVYNTRKDTW 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB5 TLICTKGSPARWRDFHSATML---GSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTE : . . : : : :.:... :....::::. :. .... . . . :. :. CCDS10 TKVDIPSPPPR-RCAHQAVVVPQGGGQLWVFGGE---FASPNGEQFYHYKDLWVLHLATK 110 120 130 140 150 160 230 240 250 260 270 280 pF1KB5 AWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGYN--ARLNRHFHDLWKFNPVSFTWKKIE .: . : : :: .: ... .: .:::.. .: ...:.. :: .:::.:. CCDS10 TWEQVKSTGG-PSGRSGHRMVAWKRQLILFGGFHESTRDYIYYNDVYAFNLDTFTWSKLS 170 180 190 200 210 220 290 300 310 320 330 pF1KB5 PKGKGPCPRRRQCCCIVGDK--IVLFGGTSPSPEEGLGDEFDL-IDHSDLHILDFSPSLK :.: :: :: : : . ::..:: : .. . . : :::. .: CCDS10 PSGTGPTPRS-GCQMSVTPQGGIVVYGGYS---KQRVKKDVDKGTRHSDMFLLKPEDGRE 230 240 250 260 270 340 350 360 370 380 pF1KB5 TLCKLAVIQYNLDQSCLPHDIRWELNAMTTNSNISRPIVSSHG CCDS10 DKWVWTRMNPSGVKPTPRSGFSVAMAPNHQTLFFGGVCDEEEEESLSGEFFNDLYFYDAT 280 290 300 310 320 330 >>CCDS55341.1 RABEPK gene_id:10244|Hs108|chr9 (321 aa) initn: 203 init1: 112 opt: 256 Z-score: 324.2 bits: 68.5 E(32554): 9.8e-12 Smith-Waterman score: 311; 30.7% identity (55.2% similar) in 212 aa overlap (115-312:18-213) 90 100 110 120 130 pF1KB5 IDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVL-------- :.: : : : :: ::: : CCDS55 MKQLPVLEPGDKPRKATWYTLTVPGDSPCARVGHSCSYLPPVGNAKR 10 20 30 40 140 150 160 170 180 190 pF1KB5 GKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFH-SATMLGSHMYVF ::. .: :: . . . :: :.: .: : ::: . . : : :: :.. .:...::: CCDS55 GKV-FIVGGANPNRS-FS-DVHTMDLETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVF 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB5 GGRADRFGPFHSNNEIYCNRIRVFDTRTEAW-----LDCPPTPVLPEGRRSHSAFGYNGE :: ..: . . . ....:::. : .: : ::.: :..: . . . CCDS55 GG-GER-----GAQPVQDTKLHVFDANTLTWSQPETLGNPPSP-----RHGHVMVAAGTK 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 LYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTS :.: :: . .: . :: .. .. :.:..: : .: . .: .. .::: . CCDS55 LFIHGGLAG--DRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMT 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 PSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELNAMTTN :. CCDS55 PAGALDTMYQYHTEEQHWTLLKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHE 220 230 240 250 260 270 >>CCDS6862.1 RABEPK gene_id:10244|Hs108|chr9 (372 aa) initn: 242 init1: 112 opt: 247 Z-score: 311.8 bits: 66.4 E(32554): 4.8e-11 Smith-Waterman score: 318; 26.0% identity (53.7% similar) in 281 aa overlap (25-299:49-301) 10 20 30 40 50 pF1KB5 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSL .:. :: .... ::: .. . CCDS68 YTLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANPNRSFS-----DVHTMDLGKH 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB5 RWTKLPPVKSAIRGQAPVVPYMRYGHSTVL---IDDTVLLWGGRNDTEGACNVLYAFDVN .: .. .: : :: :.. . : . ..:: :.. : : : ... . CCDS68 QWDL-----DTCKGLLP-----RYEHASFIPSCTPDRIWVFGGANQS-GNRNCLQVLNPE 80 90 100 110 120 120 130 140 150 160 pF1KB5 THKWFTPRVSGTVPGARDGH-SACVLGKIMYIFGGYEQQADCFSND-IHKLDTSTMTWTL :. : ::.:.. :. : : :. ..:. .:.::: :. :. .. .: .:..:.::. CCDS68 TRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 ICTKGSPARWRDFHSATMLGSHMYVFGGRA-DRFGPFHSNNEIYCNRIRVFDTRTEAWLD : :.: : : . :..... :: : ::: ....: : . : . : CCDS68 PETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRF-----YDDLHC--IDISDMK---WQK 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 CPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGP :: . : : .::: ... ..:::::.. . ..... : .. : CCDS68 LNPTGAAPAGCAAHSAVAMGKHVYIFGGMTP--AGALDTMYQYHTEEQHWTLLKFDTLLP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 CPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQ : . ::. CCDS68 PGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMSHSGDSHEESQTATLLC 300 310 320 330 340 350 382 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:14:10 2016 done: Sat Nov 5 06:14:10 2016 Total Scan time: 2.750 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]