FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5004, 382 aa 1>>>pF1KB5004 382 - 382 aa - 382 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6859+/-0.000329; mu= 19.7302+/- 0.020 mean_var=63.8449+/-13.021, 0's: 0 Z-trim(114.5): 108 B-trim: 1300 in 1/53 Lambda= 0.160513 statistics sampled from 24294 (24417) to 24294 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.286), width: 16 Scan time: 7.520 The best scores are: opt bits E(85289) NP_476502 (OMIM: 611248) kelch domain-containing p ( 382) 2731 641.2 1.2e-183 NP_006758 (OMIM: 600574,615670,616564) leucine-zip ( 840) 280 73.9 1.6e-12 XP_016869672 (OMIM: 605962) PREDICTED: rab9 effect ( 241) 256 67.9 2.9e-11 NP_001167624 (OMIM: 605962) rab9 effector protein ( 321) 256 68.0 3.6e-11 XP_005251698 (OMIM: 605962) PREDICTED: rab9 effect ( 329) 256 68.0 3.6e-11 XP_011516422 (OMIM: 605962) PREDICTED: rab9 effect ( 300) 247 65.9 1.4e-10 XP_016869668 (OMIM: 605962) PREDICTED: rab9 effect ( 305) 247 65.9 1.5e-10 NP_005824 (OMIM: 605962) rab9 effector protein wit ( 372) 247 66.0 1.7e-10 XP_016869666 (OMIM: 605962) PREDICTED: rab9 effect ( 372) 247 66.0 1.7e-10 NP_001167623 (OMIM: 605962) rab9 effector protein ( 372) 247 66.0 1.7e-10 XP_005251697 (OMIM: 605962) PREDICTED: rab9 effect ( 380) 247 66.0 1.7e-10 NP_751943 (OMIM: 611281) kelch domain-containing p ( 406) 233 62.7 1.7e-09 XP_011534724 (OMIM: 611281) PREDICTED: kelch domai ( 354) 232 62.5 1.8e-09 NP_001193976 (OMIM: 603130) attractin isoform 4 [H (1156) 216 59.2 5.7e-08 NP_647538 (OMIM: 603130) attractin isoform 2 prepr (1272) 216 59.2 6.2e-08 NP_001310261 (OMIM: 603130) attractin isoform 5 pr (1289) 216 59.2 6.2e-08 NP_647537 (OMIM: 603130) attractin isoform 1 prepr (1429) 216 59.3 6.7e-08 XP_016884960 (OMIM: 300019,309541) PREDICTED: host (2013) 211 58.2 1.9e-07 NP_005325 (OMIM: 300019,309541) host cell factor 1 (2035) 211 58.2 2e-07 XP_011529450 (OMIM: 300019,309541) PREDICTED: host (2038) 211 58.2 2e-07 XP_011529449 (OMIM: 300019,309541) PREDICTED: host (2039) 211 58.2 2e-07 XP_006724879 (OMIM: 300019,309541) PREDICTED: host (2079) 211 58.2 2e-07 XP_006724878 (OMIM: 300019,309541) PREDICTED: host (2080) 211 58.2 2e-07 NP_001003760 (OMIM: 610749) kelch-like protein 31 ( 634) 179 50.4 1.4e-05 XP_016866347 (OMIM: 610749) PREDICTED: kelch-like ( 634) 179 50.4 1.4e-05 XP_005249164 (OMIM: 610749) PREDICTED: kelch-like ( 634) 179 50.4 1.4e-05 XP_016874731 (OMIM: 607926) PREDICTED: host cell f ( 636) 170 48.3 5.9e-05 XP_016874730 (OMIM: 607926) PREDICTED: host cell f ( 736) 170 48.4 6.6e-05 NP_037452 (OMIM: 607926) host cell factor 2 [Homo ( 792) 170 48.4 6.9e-05 XP_006710761 (OMIM: 609109) PREDICTED: F-box only ( 717) 168 47.9 8.9e-05 NP_061867 (OMIM: 609109) F-box only protein 42 [Ho ( 717) 168 47.9 8.9e-05 XP_016856991 (OMIM: 609109) PREDICTED: F-box only ( 486) 165 47.1 0.00011 XP_016856992 (OMIM: 609109) PREDICTED: F-box only ( 486) 165 47.1 0.00011 XP_006713079 (OMIM: 246000,613169) PREDICTED: kelc ( 364) 160 45.8 0.00019 XP_005264997 (OMIM: 246000,613169) PREDICTED: kelc ( 227) 154 44.2 0.00035 XP_006713078 (OMIM: 246000,613169) PREDICTED: kelc ( 371) 153 44.2 0.0006 XP_016869670 (OMIM: 605962) PREDICTED: rab9 effect ( 267) 140 41.1 0.0038 XP_016869669 (OMIM: 605962) PREDICTED: rab9 effect ( 267) 140 41.1 0.0038 XP_016869671 (OMIM: 605962) PREDICTED: rab9 effect ( 267) 140 41.1 0.0038 XP_005251701 (OMIM: 605962) PREDICTED: rab9 effect ( 275) 140 41.1 0.0039 NP_067646 (OMIM: 614522) kelch-like protein 12 iso ( 568) 143 42.0 0.0041 XP_016869667 (OMIM: 605962) PREDICTED: rab9 effect ( 318) 140 41.1 0.0043 NP_001289980 (OMIM: 614522) kelch-like protein 12 ( 606) 143 42.1 0.0043 XP_005251699 (OMIM: 605962) PREDICTED: rab9 effect ( 326) 140 41.1 0.0044 NP_001161775 (OMIM: 300655) kelch-like protein 13 ( 613) 141 41.6 0.006 NP_001161773 (OMIM: 300655) kelch-like protein 13 ( 639) 141 41.6 0.0062 XP_016885439 (OMIM: 300655) PREDICTED: kelch-like ( 639) 141 41.6 0.0062 NP_001161774 (OMIM: 300655) kelch-like protein 13 ( 639) 141 41.6 0.0062 NP_001161772 (OMIM: 300655) kelch-like protein 13 ( 649) 141 41.6 0.0063 XP_011529713 (OMIM: 300655) PREDICTED: kelch-like ( 655) 141 41.6 0.0063 >>NP_476502 (OMIM: 611248) kelch domain-containing prote (382 aa) initn: 2731 init1: 2731 opt: 2731 Z-score: 3418.1 bits: 641.2 E(85289): 1.2e-183 Smith-Waterman score: 2731; 100.0% identity (100.0% similar) in 382 aa overlap (1-382:1-382) 10 20 30 40 50 60 pF1KB5 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 PVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 PVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 SGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 DFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 DFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 SHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 DKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDI 310 320 330 340 350 360 370 380 pF1KB5 RWELNAMTTNSNISRPIVSSHG :::::::::::::::::::::: NP_476 RWELNAMTTNSNISRPIVSSHG 370 380 >>NP_006758 (OMIM: 600574,615670,616564) leucine-zipper- (840 aa) initn: 281 init1: 128 opt: 280 Z-score: 346.0 bits: 73.9 E(85289): 1.6e-12 Smith-Waterman score: 301; 29.5% identity (55.6% similar) in 241 aa overlap (113-336:52-278) 90 100 110 120 130 140 pF1KB5 VLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFT-PRVSGTVPGARDGHSACVLGKIMY :.: : . : . :. :.. . .: NP_006 SKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIY 30 40 50 60 70 80 150 160 170 180 190 200 pF1KB5 IFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSATMLGSHMYVFGGRADR .::: ... . ::. ..:.. .: : :.: : :::.. :: :.:::: . NP_006 VFGG--DNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYT-- 90 100 110 120 130 210 220 230 240 250 pF1KB5 FGPFHSNNEIYCNRIRVFDTR--TEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGY-- : ..::... :. .:. . : : . :: .: .:.: :. .:.::.:: NP_006 -GDIYSNSNLK-NKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDG 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB5 NARLNRHFHDLWK--FNPVSFT-WKKIEPKGKGPCPRRRQCC----CIVGDKIVLFGGTS ::::: :.: .. .: :... .:. : : .:: . ::. .:.: : NP_006 NARLN----DMWTIGLQDRELTCWEEVAQSGEIP-P---SCCNFPVAVCRDKMFVFSGQS 200 210 220 230 240 320 330 340 350 360 pF1KB5 PSPEEGLGDEFDLIDHS-----DLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELN . . .:.. :.. :.: :: NP_006 GAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTL 250 260 270 280 290 300 370 380 pF1KB5 AMTTNSNISRPIVSSHG NP_006 PNELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTLTYEERVGFKKSRDVFGL 310 320 330 340 350 360 >-- initn: 132 init1: 78 opt: 173 Z-score: 212.1 bits: 49.1 E(85289): 4.5e-05 Smith-Waterman score: 173; 30.3% identity (55.3% similar) in 132 aa overlap (74-200:281-408) 50 60 70 80 90 100 pF1KB5 IDVHIFNAVSLRWTKLPPVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACN : ::::. : .: . ..:: :. : NP_006 ITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLP-N 260 270 280 290 300 110 120 130 140 150 pF1KB5 VLYAFDVNTHKW--FTPRVSGTVPGARDGHSACVLGKIMYIFGGYEQQADCF--SNDIHK :. .::. . : : .. : ::. . ::. .. . ::... : : :. NP_006 ELHCYDVDFQTWEVVQPSSDSEVGGAEVPERACASEEVPTL--TYEERVG-FKKSRDVFG 310 320 330 340 350 360 160 170 180 190 200 210 pF1KB5 LDTSTMTWTLICTKGSP-ARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRV :: .: . .: : ::.:..... ::.::: .: NP_006 LDFGTTSAKQPTQPASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPK 370 380 390 400 410 420 220 230 240 250 260 270 pF1KB5 FDTRTEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTW NP_006 CTLHEDYGRLWESRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKITQARERLAQKLE 430 440 450 460 470 480 >>XP_016869672 (OMIM: 605962) PREDICTED: rab9 effector p (241 aa) initn: 176 init1: 112 opt: 256 Z-score: 323.3 bits: 67.9 E(85289): 2.9e-11 Smith-Waterman score: 311; 30.7% identity (55.2% similar) in 212 aa overlap (115-312:18-213) 90 100 110 120 130 pF1KB5 IDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVL-------- :.: : : : :: ::: : XP_016 MKQLPVLEPGDKPRKATWYTLTVPGDSPCARVGHSCSYLPPVGNAKR 10 20 30 40 140 150 160 170 180 190 pF1KB5 GKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFH-SATMLGSHMYVF ::. .: :: . . . :: :.: .: : ::: . . : : :: :.. .:...::: XP_016 GKV-FIVGGANPNRS-FS-DVHTMDLETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVF 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB5 GGRADRFGPFHSNNEIYCNRIRVFDTRTEAW-----LDCPPTPVLPEGRRSHSAFGYNGE :: ..: . . . ....:::. : .: : ::.: :..: . . . XP_016 GG-GER-----GAQPVQDTKLHVFDANTLTWSQPETLGNPPSP-----RHGHVMVAAGTK 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 LYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTS :.: :: . .: . :: .. .. :.:..: : .: . .: .. .::: . XP_016 LFIHGGLAG--DRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMT 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 PSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELNAMTTN :. XP_016 PAGALDTMYQYHTETGFHRVSQDGLHLLTS 220 230 240 >>NP_001167624 (OMIM: 605962) rab9 effector protein with (321 aa) initn: 203 init1: 112 opt: 256 Z-score: 321.6 bits: 68.0 E(85289): 3.6e-11 Smith-Waterman score: 311; 30.7% identity (55.2% similar) in 212 aa overlap (115-312:18-213) 90 100 110 120 130 pF1KB5 IDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVL-------- :.: : : : :: ::: : NP_001 MKQLPVLEPGDKPRKATWYTLTVPGDSPCARVGHSCSYLPPVGNAKR 10 20 30 40 140 150 160 170 180 190 pF1KB5 GKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFH-SATMLGSHMYVF ::. .: :: . . . :: :.: .: : ::: . . : : :: :.. .:...::: NP_001 GKV-FIVGGANPNRS-FS-DVHTMDLETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVF 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB5 GGRADRFGPFHSNNEIYCNRIRVFDTRTEAW-----LDCPPTPVLPEGRRSHSAFGYNGE :: ..: . . . ....:::. : .: : ::.: :..: . . . NP_001 GG-GER-----GAQPVQDTKLHVFDANTLTWSQPETLGNPPSP-----RHGHVMVAAGTK 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 LYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTS :.: :: . .: . :: .. .. :.:..: : .: . .: .. .::: . NP_001 LFIHGGLAG--DRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMT 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 PSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELNAMTTN :. NP_001 PAGALDTMYQYHTEEQHWTLLKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHE 220 230 240 250 260 270 >>XP_005251698 (OMIM: 605962) PREDICTED: rab9 effector p (329 aa) initn: 203 init1: 112 opt: 256 Z-score: 321.5 bits: 68.0 E(85289): 3.6e-11 Smith-Waterman score: 311; 30.7% identity (55.2% similar) in 212 aa overlap (115-312:26-221) 90 100 110 120 130 pF1KB5 IDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVL-------- :.: : : : :: ::: : XP_005 MQEIVEDTMKQLPVLEPGDKPRKATWYTLTVPGDSPCARVGHSCSYLPPVGNAKR 10 20 30 40 50 140 150 160 170 180 190 pF1KB5 GKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFH-SATMLGSHMYVF ::. .: :: . . . :: :.: .: : ::: . . : : :: :.. .:...::: XP_005 GKV-FIVGGANPNRS-FS-DVHTMDLETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVF 60 70 80 90 100 110 200 210 220 230 240 250 pF1KB5 GGRADRFGPFHSNNEIYCNRIRVFDTRTEAW-----LDCPPTPVLPEGRRSHSAFGYNGE :: ..: . . . ....:::. : .: : ::.: :..: . . . XP_005 GG-GER-----GAQPVQDTKLHVFDANTLTWSQPETLGNPPSP-----RHGHVMVAAGTK 120 130 140 150 160 260 270 280 290 300 310 pF1KB5 LYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTS :.: :: . .: . :: .. .. :.:..: : .: . .: .. .::: . XP_005 LFIHGGLAG--DRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMT 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 PSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELNAMTTN :. XP_005 PAGALDTMYQYHTEEQHWTLLKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHE 220 230 240 250 260 270 >>XP_011516422 (OMIM: 605962) PREDICTED: rab9 effector p (300 aa) initn: 215 init1: 112 opt: 247 Z-score: 310.7 bits: 65.9 E(85289): 1.4e-10 Smith-Waterman score: 313; 29.4% identity (55.9% similar) in 238 aa overlap (25-256:57-268) 10 20 30 40 50 pF1KB5 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSL .:. :: .... ::: .. . XP_011 YTLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANPNRSFS-----DVHTMDLGKH 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB5 RWTKLPPVKSAIRGQAPVVPYMRYGHSTVL---IDDTVLLWGGRNDTEGACNVLYAFDVN .: : : : : :: :.. . : . ..:: :.. : : : ... . XP_011 QWD-LDTCK----GLLP-----RYEHASFIPSCTPDRIWVFGGANQS-GNRNCLQVLNPE 90 100 110 120 130 120 130 140 150 160 pF1KB5 THKWFTPRVSGTVPGARDGH-SACVLGKIMYIFGGYEQQADCFSND-IHKLDTSTMTWTL :. : ::.:.. :. : : :. ..:. .:.::: :. :. .. .: .:..:.::. XP_011 TRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQ 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB5 ICTKGSPARWRDFHSATMLGSHMYVFGGRA-DRFGPFHSNNEIYCNRIRVFDTRTEAWLD : :.: : : . :..... :: : ::: ....: : . : . : XP_011 PETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRF-----YDDLHC--IDISDMK---WQK 200 210 220 230 240 230 240 250 260 270 280 pF1KB5 CPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGP :: . : : .::: ... ..::::: XP_011 LNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTETGFHRVSQDGLHLLTS 250 260 270 280 290 300 >>XP_016869668 (OMIM: 605962) PREDICTED: rab9 effector p (305 aa) initn: 203 init1: 112 opt: 247 Z-score: 310.6 bits: 65.9 E(85289): 1.5e-10 Smith-Waterman score: 314; 27.9% identity (56.3% similar) in 229 aa overlap (77-299:19-234) 50 60 70 80 90 100 pF1KB5 HIFNAVSLRWTKLPPVKSAIRGQAPVVPYMRYGHSTVL---IDDTVLLWGGRNDTEGACN :: :.. . : . ..:: :.. : : XP_016 MDLGKHQWDLDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQS-GNRN 10 20 30 40 110 120 130 140 150 160 pF1KB5 VLYAFDVNTHKWFTPRVSGTVPGARDGH-SACVLGKIMYIFGGYEQQADCFSND-IHKLD : ... .:. : ::.:.. :. : : :. ..:. .:.::: :. :. .. .: .: XP_016 CLQVLNPETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFD 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB5 TSTMTWTLICTKGSPARWRDFHSATMLGSHMYVFGGRA-DRFGPFHSNNEIYCNRIRVFD ..:.::. : :.: : : . :..... :: : ::: ....: : . : XP_016 ANTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRF-----YDDLHC--IDISD 110 120 130 140 150 160 230 240 250 260 270 280 pF1KB5 TRTEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKK . : :: . : : .::: ... ..:::::.. . ..... : XP_016 MK---WQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTP--AGALDTMYQYHTEEQHWTL 170 180 190 200 210 290 300 310 320 330 340 pF1KB5 IEPKGKGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKT .. : : . ::. XP_016 LKFDTLLPPGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMSHSGDSHEE 220 230 240 250 260 270 >>NP_005824 (OMIM: 605962) rab9 effector protein with ke (372 aa) initn: 242 init1: 112 opt: 247 Z-score: 309.5 bits: 66.0 E(85289): 1.7e-10 Smith-Waterman score: 318; 26.0% identity (53.7% similar) in 281 aa overlap (25-299:49-301) 10 20 30 40 50 pF1KB5 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSL .:. :: .... ::: .. . NP_005 YTLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANPNRSFS-----DVHTMDLGKH 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB5 RWTKLPPVKSAIRGQAPVVPYMRYGHSTVL---IDDTVLLWGGRNDTEGACNVLYAFDVN .: .. .: : :: :.. . : . ..:: :.. : : : ... . NP_005 QWDL-----DTCKGLLP-----RYEHASFIPSCTPDRIWVFGGANQS-GNRNCLQVLNPE 80 90 100 110 120 120 130 140 150 160 pF1KB5 THKWFTPRVSGTVPGARDGH-SACVLGKIMYIFGGYEQQADCFSND-IHKLDTSTMTWTL :. : ::.:.. :. : : :. ..:. .:.::: :. :. .. .: .:..:.::. NP_005 TRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 ICTKGSPARWRDFHSATMLGSHMYVFGGRA-DRFGPFHSNNEIYCNRIRVFDTRTEAWLD : :.: : : . :..... :: : ::: ....: : . : . : NP_005 PETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRF-----YDDLHC--IDISDMK---WQK 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 CPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGP :: . : : .::: ... ..:::::.. . ..... : .. : NP_005 LNPTGAAPAGCAAHSAVAMGKHVYIFGGMTP--AGALDTMYQYHTEEQHWTLLKFDTLLP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 CPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQ : . ::. NP_005 PGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMSHSGDSHEESQTATLLC 300 310 320 330 340 350 >>XP_016869666 (OMIM: 605962) PREDICTED: rab9 effector p (372 aa) initn: 242 init1: 112 opt: 247 Z-score: 309.5 bits: 66.0 E(85289): 1.7e-10 Smith-Waterman score: 318; 26.0% identity (53.7% similar) in 281 aa overlap (25-299:49-301) 10 20 30 40 50 pF1KB5 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSL .:. :: .... ::: .. . XP_016 YTLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANPNRSFS-----DVHTMDLGKH 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB5 RWTKLPPVKSAIRGQAPVVPYMRYGHSTVL---IDDTVLLWGGRNDTEGACNVLYAFDVN .: .. .: : :: :.. . : . ..:: :.. : : : ... . XP_016 QWDL-----DTCKGLLP-----RYEHASFIPSCTPDRIWVFGGANQS-GNRNCLQVLNPE 80 90 100 110 120 120 130 140 150 160 pF1KB5 THKWFTPRVSGTVPGARDGH-SACVLGKIMYIFGGYEQQADCFSND-IHKLDTSTMTWTL :. : ::.:.. :. : : :. ..:. .:.::: :. :. .. .: .:..:.::. XP_016 TRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 ICTKGSPARWRDFHSATMLGSHMYVFGGRA-DRFGPFHSNNEIYCNRIRVFDTRTEAWLD : :.: : : . :..... :: : ::: ....: : . : . : XP_016 PETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRF-----YDDLHC--IDISDMK---WQK 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 CPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGP :: . : : .::: ... ..:::::.. . ..... : .. : XP_016 LNPTGAAPAGCAAHSAVAMGKHVYIFGGMTP--AGALDTMYQYHTEEQHWTLLKFDTLLP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 CPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQ : . ::. XP_016 PGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMSHSGDSHEESQTATLLC 300 310 320 330 340 350 >>NP_001167623 (OMIM: 605962) rab9 effector protein with (372 aa) initn: 242 init1: 112 opt: 247 Z-score: 309.5 bits: 66.0 E(85289): 1.7e-10 Smith-Waterman score: 318; 26.0% identity (53.7% similar) in 281 aa overlap (25-299:49-301) 10 20 30 40 50 pF1KB5 MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSL .:. :: .... ::: .. . NP_001 YTLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANPNRSFS-----DVHTMDLGKH 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB5 RWTKLPPVKSAIRGQAPVVPYMRYGHSTVL---IDDTVLLWGGRNDTEGACNVLYAFDVN .: .. .: : :: :.. . : . ..:: :.. : : : ... . NP_001 QWDL-----DTCKGLLP-----RYEHASFIPSCTPDRIWVFGGANQS-GNRNCLQVLNPE 80 90 100 110 120 120 130 140 150 160 pF1KB5 THKWFTPRVSGTVPGARDGH-SACVLGKIMYIFGGYEQQADCFSND-IHKLDTSTMTWTL :. : ::.:.. :. : : :. ..:. .:.::: :. :. .. .: .:..:.::. NP_001 TRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 ICTKGSPARWRDFHSATMLGSHMYVFGGRA-DRFGPFHSNNEIYCNRIRVFDTRTEAWLD : :.: : : . :..... :: : ::: ....: : . : . : NP_001 PETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRF-----YDDLHC--IDISDMK---WQK 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 CPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGP :: . : : .::: ... ..:::::.. . ..... : .. : NP_001 LNPTGAAPAGCAAHSAVAMGKHVYIFGGMTP--AGALDTMYQYHTEEQHWTLLKFDTLLP 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB5 CPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQ : . ::. NP_001 PGRLDHSMCIIPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMSHSGDSHEESQTATLLC 300 310 320 330 340 350 382 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:14:11 2016 done: Sat Nov 5 06:14:12 2016 Total Scan time: 7.520 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]