FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5006, 459 aa 1>>>pF1KB5006 459 - 459 aa - 459 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8538+/-0.000386; mu= 15.7839+/- 0.024 mean_var=94.9851+/-18.940, 0's: 0 Z-trim(114.2): 146 B-trim: 19 in 1/50 Lambda= 0.131597 statistics sampled from 23785 (23938) to 23785 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.281), width: 16 Scan time: 9.770 The best scores are: opt bits E(85289) NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans ( 459) 2992 578.6 1.2e-164 XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-pr ( 414) 2708 524.6 1.9e-148 NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 1730 339.0 1.6e-92 NP_004108 (OMIM: 602623,608516) peptidyl-prolyl ci ( 457) 1730 339.0 1.6e-92 NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 1730 339.0 1.6e-92 NP_001139249 (OMIM: 602623,608516) peptidyl-prolyl ( 268) 897 180.7 4.3e-45 NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 338 74.2 1.9e-13 NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 338 74.2 1.9e-13 NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans ( 108) 322 71.2 1.6e-12 XP_011526165 (OMIM: 604840) PREDICTED: peptidyl-pr ( 413) 313 69.9 1.4e-11 NP_036313 (OMIM: 604840) peptidyl-prolyl cis-trans ( 413) 313 69.9 1.4e-11 NP_001295302 (OMIM: 604840) peptidyl-prolyl cis-tr ( 412) 311 69.6 1.9e-11 XP_011513417 (OMIM: 616257) PREDICTED: peptidyl-pr ( 359) 300 67.4 7.1e-11 NP_009201 (OMIM: 616257) peptidyl-prolyl cis-trans ( 570) 300 67.6 1e-10 XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-pr ( 142) 291 65.4 1.1e-10 NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 291 65.4 1.1e-10 NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-tr ( 142) 291 65.4 1.1e-10 NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 291 65.4 1.1e-10 XP_011534867 (OMIM: 186947) PREDICTED: peptidyl-pr ( 191) 287 64.7 2.4e-10 NP_005029 (OMIM: 601753) peptidyl-prolyl cis-trans ( 370) 290 65.5 2.7e-10 NP_002004 (OMIM: 186947) peptidyl-prolyl cis-trans ( 224) 287 64.8 2.7e-10 XP_011526166 (OMIM: 604840) PREDICTED: peptidyl-pr ( 383) 290 65.5 2.8e-10 NP_001309893 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 264 60.1 2.5e-09 XP_016859082 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 264 60.1 2.5e-09 XP_016859084 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 264 60.1 2.5e-09 XP_016859083 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 264 60.1 2.5e-09 NP_001309892 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 264 60.1 2.5e-09 XP_016859085 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 264 60.1 2.5e-09 NP_071393 (OMIM: 617076) FK506-binding protein-lik ( 349) 272 62.1 2.8e-09 NP_068758 (OMIM: 259450,607063,610968) peptidyl-pr ( 582) 268 61.5 7e-09 XP_016868231 (OMIM: 604839) PREDICTED: inactive pe ( 266) 262 60.1 8.4e-09 XP_006716216 (OMIM: 604839) PREDICTED: inactive pe ( 282) 262 60.1 8.8e-09 XP_016868230 (OMIM: 604839) PREDICTED: inactive pe ( 317) 262 60.2 9.6e-09 NP_001128683 (OMIM: 604839) inactive peptidyl-prol ( 322) 262 60.2 9.7e-09 NP_003593 (OMIM: 604839) inactive peptidyl-prolyl ( 327) 262 60.2 9.9e-09 NP_001289888 (OMIM: 102200,219090,600634,605555) A ( 271) 248 57.5 5.4e-08 NP_003968 (OMIM: 102200,219090,600634,605555) AH r ( 330) 248 57.5 6.3e-08 NP_001128684 (OMIM: 607062) peptidyl-prolyl cis-tr ( 221) 236 55.1 2.2e-07 XP_016876582 (OMIM: 186947) PREDICTED: peptidyl-pr ( 196) 233 54.5 3e-07 XP_016876581 (OMIM: 186947) PREDICTED: peptidyl-pr ( 229) 233 54.5 3.4e-07 NP_001028226 (OMIM: 268000,604392,604393) aryl-hyd ( 321) 228 53.7 8.5e-07 NP_001028227 (OMIM: 268000,604392,604393) aryl-hyd ( 324) 228 53.7 8.6e-07 NP_001272331 (OMIM: 268000,604392,604393) aryl-hyd ( 345) 228 53.7 9e-07 NP_001272329 (OMIM: 268000,604392,604393) aryl-hyd ( 362) 228 53.8 9.4e-07 NP_001272328 (OMIM: 268000,604392,604393) aryl-hyd ( 372) 228 53.8 9.6e-07 NP_055151 (OMIM: 268000,604392,604393) aryl-hydroc ( 384) 228 53.8 9.8e-07 XP_011523402 (OMIM: 259450,607063,610968) PREDICTE ( 510) 228 53.9 1.2e-06 XP_011523401 (OMIM: 259450,607063,610968) PREDICTE ( 601) 228 53.9 1.4e-06 XP_011510364 (OMIM: 611397) PREDICTED: protein TAN (1554) 233 55.2 1.5e-06 XP_016860646 (OMIM: 611397) PREDICTED: protein TAN (1660) 233 55.2 1.6e-06 >>NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans iso (459 aa) initn: 2992 init1: 2992 opt: 2992 Z-score: 3076.9 bits: 578.6 E(85289): 1.2e-164 Smith-Waterman score: 2992; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459) 10 20 30 40 50 60 pF1KB5 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 370 380 390 400 410 420 430 440 450 pF1KB5 EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA ::::::::::::::::::::::::::::::::::::::: NP_002 EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA 430 440 450 >>XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-prolyl (414 aa) initn: 2708 init1: 2708 opt: 2708 Z-score: 2786.1 bits: 524.6 E(85289): 1.9e-148 Smith-Waterman score: 2708; 100.0% identity (100.0% similar) in 414 aa overlap (46-459:1-414) 20 30 40 50 60 70 pF1KB5 APLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKD :::::::::::::::::::::::::::::: XP_011 MPMIGDRVFVHYTGWLLDGTKFDSSLDRKD 10 20 30 80 90 100 110 120 130 pF1KB5 KFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELF 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB5 EFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEG 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB5 ENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB5 KESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQ 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB5 ALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARAD 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB5 FQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHP 340 350 360 370 380 390 440 450 pF1KB5 TDTEMKEEQKSNTAGSQSQVETEA :::::::::::::::::::::::: XP_011 TDTEMKEEQKSNTAGSQSQVETEA 400 410 >>NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl cis (457 aa) initn: 1729 init1: 1125 opt: 1730 Z-score: 1782.0 bits: 339.0 E(85289): 1.6e-92 Smith-Waterman score: 1730; 55.2% identity (80.6% similar) in 458 aa overlap (1-458:1-450) 10 20 30 40 50 60 pF1KB5 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW ::..: .. . .: . .: ::. :.:.::::..:: :.: : :::::.:.::: : NP_001 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP : .: ::::: ::.. : :.::::.:::::::..:::: ::.::. :::::::::::: : NP_001 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD ::: :::: ::.::..:::::: :::::::: . .::::..::::: ::. ::: NP_001 KIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN ..:: :.. : .::::. :.: :...:...:.. :. :.:: : :.:: .:: :: : :: NP_001 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL ::: ::. :::::::::::::...:::::..::::.:::::: ::: ::..:: :::::: NP_001 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG :.: ..:..:.. .... ::. ::::::.:::. .. :.: :.::: ::: :::::.::: NP_001 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE ::.: .:.:: :..::.:::.. :.::::. :...::.. ... :....:::::...:: NP_001 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 360 370 380 390 400 410 430 440 450 pF1KB5 EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA .. : .:. . : . . : .: :..::. : NP_001 QDAKEEANKAMGKKTS------EGVTNEKGTDSQAMEEEKPEGHV 420 430 440 450 >>NP_004108 (OMIM: 602623,608516) peptidyl-prolyl cis-tr (457 aa) initn: 1729 init1: 1125 opt: 1730 Z-score: 1782.0 bits: 339.0 E(85289): 1.6e-92 Smith-Waterman score: 1730; 55.2% identity (80.6% similar) in 458 aa overlap (1-458:1-450) 10 20 30 40 50 60 pF1KB5 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW ::..: .. . .: . .: ::. :.:.::::..:: :.: : :::::.:.::: : NP_004 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP : .: ::::: ::.. : :.::::.:::::::..:::: ::.::. :::::::::::: : NP_004 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD ::: :::: ::.::..:::::: :::::::: . .::::..::::: ::. ::: NP_004 KIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN ..:: :.. : .::::. :.: :...:...:.. :. :.:: : :.:: .:: :: : :: NP_004 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL ::: ::. :::::::::::::...:::::..::::.:::::: ::: ::..:: :::::: NP_004 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG :.: ..:..:.. .... ::. ::::::.:::. .. :.: :.::: ::: :::::.::: NP_004 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE ::.: .:.:: :..::.:::.. :.::::. :...::.. ... :....:::::...:: NP_004 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 360 370 380 390 400 410 430 440 450 pF1KB5 EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA .. : .:. . : . . : .: :..::. : NP_004 QDAKEEANKAMGKKTS------EGVTNEKGTDSQAMEEEKPEGHV 420 430 440 450 >>NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl cis (457 aa) initn: 1729 init1: 1125 opt: 1730 Z-score: 1782.0 bits: 339.0 E(85289): 1.6e-92 Smith-Waterman score: 1730; 55.2% identity (80.6% similar) in 458 aa overlap (1-458:1-450) 10 20 30 40 50 60 pF1KB5 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW ::..: .. . .: . .: ::. :.:.::::..:: :.: : :::::.:.::: : NP_001 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP : .: ::::: ::.. : :.::::.:::::::..:::: ::.::. :::::::::::: : NP_001 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD ::: :::: ::.::..:::::: :::::::: . .::::..::::: ::. ::: NP_001 KIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN ..:: :.. : .::::. :.: :...:...:.. :. :.:: : :.:: .:: :: : :: NP_001 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL ::: ::. :::::::::::::...:::::..::::.:::::: ::: ::..:: :::::: NP_001 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB5 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG :.: ..:..:.. .... ::. ::::::.:::. .. :.: :.::: ::: :::::.::: NP_001 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE ::.: .:.:: :..::.:::.. :.::::. :...::.. ... :....:::::...:: NP_001 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 360 370 380 390 400 410 430 440 450 pF1KB5 EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA .. : .:. . : . . : .: :..::. : NP_001 QDAKEEANKAMGKKTS------EGVTNEKGTDSQAMEEEKPEGHV 420 430 440 450 >>NP_001139249 (OMIM: 602623,608516) peptidyl-prolyl cis (268 aa) initn: 905 init1: 618 opt: 897 Z-score: 930.5 bits: 180.7 E(85289): 4.3e-45 Smith-Waterman score: 897; 57.4% identity (79.8% similar) in 223 aa overlap (1-223:1-221) 10 20 30 40 50 60 pF1KB5 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW ::..: .. . .: . .: ::. :.:.::::..:: :.: : :::::.:.::: : NP_001 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP : .: ::::: ::.. : :.::::.:::::::..:::: ::.::. :::::::::::: : NP_001 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD ::: :::: ::.::..:::::: : ::::::: . .::::..::::: ::. ::: NP_001 KIPSNATLFFEIELLDFKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN ..:: :.. : .::::. :.: :...:...:.. :. :.:: : NP_001 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRPKNPGRWIPKKNWSRL 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB5 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL NP_001 PLSKRREPYTSRCVSPYAILSISKNLFKCW 240 250 260 >>NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans iso (108 aa) initn: 338 init1: 338 opt: 338 Z-score: 362.4 bits: 74.2 E(85289): 1.9e-13 Smith-Waterman score: 338; 52.0% identity (75.5% similar) in 98 aa overlap (41-138:11-108) 20 30 40 50 60 70 pF1KB5 SGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSS : : .: :. ::::: : :: ::::: NP_000 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS 10 20 30 40 80 90 100 110 120 130 pF1KB5 LDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVF ::. :.: ::: :::..:. ..: :.::. ..: .:.::::..: : :::.::::: NP_000 RDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB5 EVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRF .:::.... NP_000 DVELLKLE >>NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans iso (108 aa) initn: 338 init1: 338 opt: 338 Z-score: 362.4 bits: 74.2 E(85289): 1.9e-13 Smith-Waterman score: 338; 52.0% identity (75.5% similar) in 98 aa overlap (41-138:11-108) 20 30 40 50 60 70 pF1KB5 SGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSS : : .: :. ::::: : :: ::::: NP_463 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS 10 20 30 40 80 90 100 110 120 130 pF1KB5 LDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVF ::. :.: ::: :::..:. ..: :.::. ..: .:.::::..: : :::.::::: NP_463 RDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVF 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB5 EVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRF .:::.... NP_463 DVELLKLE >>NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans iso (108 aa) initn: 322 init1: 322 opt: 322 Z-score: 346.0 bits: 71.2 E(85289): 1.6e-12 Smith-Waterman score: 322; 49.0% identity (73.5% similar) in 98 aa overlap (41-138:11-108) 20 30 40 50 60 70 pF1KB5 SGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSS : : .: :. ::::: : .: ::::: NP_004 MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSS 10 20 30 40 80 90 100 110 120 130 pF1KB5 LDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVF ::. :.: .:: ::::... . : :..:. ..:: :. :::..: : :::::::.: NP_004 RDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIF 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB5 EVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRF .:::.... NP_004 DVELLNLE >>XP_011526165 (OMIM: 604840) PREDICTED: peptidyl-prolyl (413 aa) initn: 391 init1: 165 opt: 313 Z-score: 328.7 bits: 69.9 E(85289): 1.4e-11 Smith-Waterman score: 313; 27.5% identity (60.7% similar) in 262 aa overlap (160-415:113-369) 130 140 150 160 170 180 pF1KB5 FEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD--KLFDQRE : ..: .: .: : :. .. .. .. : XP_011 EPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPE 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB5 LRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYEL : : .:. :. .:. .. :. :: ..: .: .: :... :::.: : :. XP_011 LVFTLGD---CDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEV 150 160 170 180 190 250 260 270 280 290 300 pF1KB5 HLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQY----KKIVSWLEYE ::. . . ....:.. .. .: :....... . : .: : :.: . . XP_011 TLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVD 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB5 SSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAH .: .:::: : :.. ::: .:::. . ::..::. .:: . .: :.:::.:.. XP_011 MTF-EEEAQLLQ-LKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVL 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB5 LAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEEN ... : .. .:.: :.::. ...:. .. : . : :: .:. XP_011 AQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPA 320 330 340 350 360 370 430 440 450 pF1KB5 KAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA XP_011 KCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN 380 390 400 410 459 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:42:52 2016 done: Thu Nov 3 15:42:53 2016 Total Scan time: 9.770 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]