FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5008, 294 aa 1>>>pF1KB5008 294 - 294 aa - 294 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6874+/-0.000404; mu= 18.9372+/- 0.025 mean_var=65.6848+/-13.139, 0's: 0 Z-trim(112.5): 83 B-trim: 0 in 0/49 Lambda= 0.158249 statistics sampled from 21406 (21500) to 21406 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.252), width: 16 Scan time: 6.100 The best scores are: opt bits E(85289) NP_036471 (OMIM: 613140) tetraspanin-15 [Homo sapi ( 294) 1991 463.4 2.4e-130 XP_011537864 (OMIM: 613140) PREDICTED: tetraspanin ( 178) 1235 290.6 1.5e-78 XP_005269724 (OMIM: 613140) PREDICTED: tetraspanin ( 207) 1233 290.2 2.3e-78 XP_005269723 (OMIM: 613140) PREDICTED: tetraspanin ( 229) 1233 290.2 2.5e-78 XP_011537865 (OMIM: 613140) PREDICTED: tetraspanin ( 150) 1064 251.5 7.4e-67 XP_016871499 (OMIM: 613140) PREDICTED: tetraspanin ( 272) 974 231.2 1.8e-60 NP_848657 (OMIM: 610120) tetraspanin-33 [Homo sapi ( 283) 671 162.0 1.2e-39 XP_006716023 (OMIM: 610120) PREDICTED: tetraspanin ( 282) 661 159.7 5.9e-39 NP_005714 (OMIM: 613136) tetraspanin-5 [Homo sapie ( 268) 594 144.4 2.3e-34 XP_005262737 (OMIM: 613136) PREDICTED: tetraspanin ( 219) 450 111.4 1.6e-24 NP_620599 (OMIM: 179620,602243,609057) CD151 antig ( 253) 342 86.8 4.6e-17 NP_620598 (OMIM: 179620,602243,609057) CD151 antig ( 253) 342 86.8 4.6e-17 NP_004348 (OMIM: 179620,602243,609057) CD151 antig ( 253) 342 86.8 4.6e-17 NP_001034579 (OMIM: 179620,602243,609057) CD151 an ( 253) 342 86.8 4.6e-17 NP_003261 (OMIM: 300191) tetraspanin-6 isoform a [ ( 245) 340 86.4 6.1e-17 NP_004606 (OMIM: 300096,300210) tetraspanin-7 [Hom ( 249) 322 82.3 1.1e-15 NP_001161792 (OMIM: 613137) tetraspanin-9 [Homo sa ( 239) 297 76.5 5.4e-14 NP_006666 (OMIM: 613137) tetraspanin-9 [Homo sapie ( 239) 297 76.5 5.4e-14 NP_001254627 (OMIM: 155740) CD63 antigen isoform A ( 238) 295 76.1 7.4e-14 NP_001244320 (OMIM: 155740) CD63 antigen isoform A ( 238) 295 76.1 7.4e-14 NP_001244319 (OMIM: 155740) CD63 antigen isoform A ( 238) 295 76.1 7.4e-14 NP_001244318 (OMIM: 155740) CD63 antigen isoform A ( 238) 295 76.1 7.4e-14 NP_001771 (OMIM: 155740) CD63 antigen isoform A [H ( 238) 295 76.1 7.4e-14 NP_001244321 (OMIM: 155740) CD63 antigen isoform C ( 215) 285 73.8 3.4e-13 XP_005253159 (OMIM: 602644) PREDICTED: tetraspanin ( 238) 279 72.4 9.4e-13 NP_001020409 (OMIM: 602644) tetraspanin-4 isoform ( 238) 279 72.4 9.4e-13 NP_001020405 (OMIM: 602644) tetraspanin-4 isoform ( 238) 279 72.4 9.4e-13 NP_003262 (OMIM: 602644) tetraspanin-4 isoform a [ ( 238) 279 72.4 9.4e-13 NP_001020406 (OMIM: 602644) tetraspanin-4 isoform ( 238) 279 72.4 9.4e-13 NP_001020408 (OMIM: 602644) tetraspanin-4 isoform ( 238) 279 72.4 9.4e-13 NP_001020407 (OMIM: 602644) tetraspanin-4 isoform ( 238) 279 72.4 9.4e-13 XP_006718286 (OMIM: 176807,600623) PREDICTED: CD82 ( 267) 270 70.4 4.2e-12 NP_002222 (OMIM: 176807,600623) CD82 antigen isofo ( 267) 270 70.4 4.2e-12 NP_005715 (OMIM: 613134) tetraspanin-3 isoform 1 [ ( 253) 263 68.8 1.2e-11 NP_005718 (OMIM: 613170) tetraspanin-1 [Homo sapie ( 241) 257 67.4 3.1e-11 XP_011538762 (OMIM: 613170) PREDICTED: tetraspanin ( 258) 257 67.4 3.2e-11 NP_000551 (OMIM: 151525) leukocyte surface antigen ( 219) 255 66.9 3.9e-11 NP_001035122 (OMIM: 151525) leukocyte surface anti ( 219) 255 66.9 3.9e-11 XP_011518638 (OMIM: 602644) PREDICTED: tetraspanin ( 269) 234 62.2 1.3e-09 XP_011518369 (OMIM: 176807,600623) PREDICTED: CD82 ( 236) 221 59.2 9e-09 NP_001244329 (OMIM: 155740) CD63 antigen isoform D ( 156) 209 56.3 4.4e-08 NP_001244330 (OMIM: 155740) CD63 antigen isoform D ( 156) 209 56.3 4.4e-08 XP_011529320 (OMIM: 300191) PREDICTED: tetraspanin ( 157) 202 54.7 1.3e-07 NP_001265669 (OMIM: 300191) tetraspanin-6 isoform ( 157) 202 54.7 1.3e-07 NP_001265670 (OMIM: 300191) tetraspanin-6 isoform ( 157) 202 54.7 1.3e-07 NP_001265671 (OMIM: 300191) tetraspanin-6 isoform ( 137) 199 54.0 2e-07 NP_001265672 (OMIM: 300191) tetraspanin-6 isoform ( 129) 194 52.8 4.1e-07 XP_011519214 (OMIM: 613137) PREDICTED: tetraspanin ( 175) 187 51.3 1.6e-06 XP_011519215 (OMIM: 613137) PREDICTED: tetraspanin ( 175) 187 51.3 1.6e-06 NP_001020015 (OMIM: 176807,600623) CD82 antigen is ( 242) 188 51.7 1.7e-06 >>NP_036471 (OMIM: 613140) tetraspanin-15 [Homo sapiens] (294 aa) initn: 1991 init1: 1991 opt: 1991 Z-score: 2461.1 bits: 463.4 E(85289): 2.4e-130 Smith-Waterman score: 1991; 100.0% identity (100.0% similar) in 294 aa overlap (1-294:1-294) 10 20 30 40 50 60 pF1KB5 MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 APAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 APAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLG 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 ILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN 250 260 270 280 290 >>XP_011537864 (OMIM: 613140) PREDICTED: tetraspanin-15 (178 aa) initn: 1235 init1: 1235 opt: 1235 Z-score: 1531.2 bits: 290.6 E(85289): 1.5e-78 Smith-Waterman score: 1235; 99.4% identity (100.0% similar) in 176 aa overlap (119-294:3-178) 90 100 110 120 130 140 pF1KB5 LYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFV .::::::::::::::::::::::::::::: XP_011 MRETIDFLNDNIRRGIENYYDDLDFKNIMDFV 10 20 30 150 160 170 180 190 200 pF1KB5 QKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERF 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB5 SVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYITRVEDIIMEHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYITRVEDIIMEHSV 100 110 120 130 140 150 270 280 290 pF1KB5 TDGLLGPGAKPSVEAAGTGCCLCYPN :::::::::::::::::::::::::: XP_011 TDGLLGPGAKPSVEAAGTGCCLCYPN 160 170 >>XP_005269724 (OMIM: 613140) PREDICTED: tetraspanin-15 (207 aa) initn: 1233 init1: 1233 opt: 1233 Z-score: 1527.9 bits: 290.2 E(85289): 2.3e-78 Smith-Waterman score: 1278; 70.4% identity (70.4% similar) in 294 aa overlap (1-294:1-207) 10 20 30 40 50 60 pF1KB5 MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFL :::::::::::::::::::::::::::::::: XP_005 MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFW---------------------------- 10 20 30 70 80 90 100 110 120 pF1KB5 APAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQT : XP_005 -----------------------------------------------------------T 130 140 150 160 170 180 pF1KB5 IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACG 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB5 VPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLG 100 110 120 130 140 150 250 260 270 280 290 pF1KB5 ILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN 160 170 180 190 200 >>XP_005269723 (OMIM: 613140) PREDICTED: tetraspanin-15 (229 aa) initn: 1233 init1: 1233 opt: 1233 Z-score: 1527.3 bits: 290.2 E(85289): 2.5e-78 Smith-Waterman score: 1233; 100.0% identity (100.0% similar) in 175 aa overlap (120-294:55-229) 90 100 110 120 130 140 pF1KB5 YLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFVQ :::::::::::::::::::::::::::::: XP_005 SVWHRSRECPLRPQSLLILDLRALKAAIVTTIDFLNDNIRRGIENYYDDLDFKNIMDFVQ 30 40 50 60 70 80 150 160 170 180 190 200 pF1KB5 KKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFS 90 100 110 120 130 140 210 220 230 240 250 260 pF1KB5 VQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYITRVEDIIMEHSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYITRVEDIIMEHSVT 150 160 170 180 190 200 270 280 290 pF1KB5 DGLLGPGAKPSVEAAGTGCCLCYPN ::::::::::::::::::::::::: XP_005 DGLLGPGAKPSVEAAGTGCCLCYPN 210 220 >>XP_011537865 (OMIM: 613140) PREDICTED: tetraspanin-15 (150 aa) initn: 1064 init1: 1064 opt: 1064 Z-score: 1321.2 bits: 251.5 E(85289): 7.4e-67 Smith-Waterman score: 1064; 100.0% identity (100.0% similar) in 150 aa overlap (145-294:1-150) 120 130 140 150 160 170 pF1KB5 TFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAP :::::::::::::::::::::::::::::: XP_011 MDFVQKKFKCCGGEDYRDWSKNQYHDCSAP 10 20 30 180 190 200 210 220 230 pF1KB5 GPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIM 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB5 AGILLGILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGILLGILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN 100 110 120 130 140 150 >>XP_016871499 (OMIM: 613140) PREDICTED: tetraspanin-15 (272 aa) initn: 974 init1: 974 opt: 974 Z-score: 1206.7 bits: 231.2 E(85289): 1.8e-60 Smith-Waterman score: 974; 100.0% identity (100.0% similar) in 151 aa overlap (1-151:1-151) 10 20 30 40 50 60 pF1KB5 MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 APAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACG ::::::::::::::::::::::::::::::: XP_016 IDFLNDNIRRGIENYYDDLDFKNIMDFVQKKGPFLSSEQGLGDDGSSSFLLASLSSSAVA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLG XP_016 GRTTEIGARISTTTAVPLDPWPVGCPTPAASGTRQKLSTPCVATKLSTRRDMDEAGSHHS 190 200 210 220 230 240 >>NP_848657 (OMIM: 610120) tetraspanin-33 [Homo sapiens] (283 aa) initn: 653 init1: 451 opt: 671 Z-score: 832.7 bits: 162.0 E(85289): 1.2e-39 Smith-Waterman score: 671; 35.8% identity (73.2% similar) in 254 aa overlap (15-263:15-268) 10 20 30 40 50 pF1KB5 MPRGDSEQVRYCARFSYL--WLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESA ::.. .:. :.... .::.:. ....::.::.. .. .: NP_848 MARRPRAPAASGEEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 FLAPAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRN . :::.::..::.::...: : ..:::.:. :::.: : ....: .:.....: . NP_848 AVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 QTIDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLA .. ... : .: .: ::::..:..:: ::::.:::: .:.:::.:.: .:: .: NP_848 KARGKVSEIINNAIVHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 --CGVPYTCCIRNTTE-VVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMA :.:::.::. . . :.::::: . . .. :::. :: . .. :. .: ... NP_848 ERCSVPYSCCLPTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 GILLGILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN :. ::. .::..:.::. . .....: : NP_848 GVALGLAIPQLVGILLSQILVNQIKDQIKLQLYNQQHRADPWY 250 260 270 280 >>XP_006716023 (OMIM: 610120) PREDICTED: tetraspanin-33 (282 aa) initn: 628 init1: 375 opt: 661 Z-score: 820.3 bits: 159.7 E(85289): 5.9e-39 Smith-Waterman score: 661; 35.8% identity (73.2% similar) in 254 aa overlap (15-263:15-267) 10 20 30 40 50 pF1KB5 MPRGDSEQVRYCARFSYL--WLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESA ::.. .:. :.... .::.:. ....::.::.. .. .: XP_006 MARRPRAPAASGEEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHA-AALACL 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 FLAPAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRN . :::.::..::.::...: : ..:::.:. :::.: : ....: .:.....: . XP_006 AVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 QTIDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLA .. ... : .: .: ::::..:..:: ::::.:::: .:.:::.:.: .:: .: XP_006 KARGKVSEIINNAIVHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 --CGVPYTCCIRNTTE-VVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMA :.:::.::. . . :.::::: . . .. :::. :: . .. :. .: ... XP_006 ERCSVPYSCCLPTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 GILLGILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN :. ::. .::..:.::. . .....: : XP_006 GVALGLAIPQLVGILLSQILVNQIKDQIKLQLYNQQHRADPWY 240 250 260 270 280 >>NP_005714 (OMIM: 613136) tetraspanin-5 [Homo sapiens] (268 aa) initn: 524 init1: 306 opt: 594 Z-score: 738.0 bits: 144.4 E(85289): 2.3e-34 Smith-Waterman score: 594; 35.0% identity (68.9% similar) in 254 aa overlap (20-262:15-264) 10 20 30 40 50 pF1KB5 MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF- .:. .. ....::..: :..:..: :. ... : NP_005 MSGKHYKGPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITD 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 ---LAPAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTF . :. .....: :::...: : ...::.: .::. : .::: ...:: .::.:..: NP_005 LGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 RNQTID----FLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDC- .. : :.:.::: : ::.:..:..::.:. ..:::. ::. : : .: NP_005 KDWIKDQLYFFINNNIR----AYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCT 120 130 140 150 160 170 180 190 200 210 220 pF1KB5 -SAPGPLACGVPYTCCIRNTTE-VVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMD : . ::::..:: .. .: :.::.::: . .: . . : :::..::. :..: NP_005 DSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQD 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB5 NYTIMAGILLGILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCC : ::.:::..:: : :..:. :. .. .: . NP_005 NLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW 240 250 260 290 pF1KB5 LCYPN >>XP_005262737 (OMIM: 613136) PREDICTED: tetraspanin-5 i (219 aa) initn: 434 init1: 216 opt: 450 Z-score: 561.4 bits: 111.4 E(85289): 1.6e-24 Smith-Waterman score: 450; 38.4% identity (68.4% similar) in 177 aa overlap (93-262:43-215) 70 80 90 100 110 120 pF1KB5 AIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTID . : .::: ...:: .::.:..:.. : XP_005 CCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKFSVFLGIIFFLELTAGVLAFVFKDWIKD 20 30 40 50 60 70 130 140 150 160 170 pF1KB5 ----FLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDC--SAPGP :.:.::: : ::.:..:..::.:. ..:::. ::. : : .: : . XP_005 QLYFFINNNIR----AYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASR 80 90 100 110 120 180 190 200 210 220 230 pF1KB5 LACGVPYTCCIRNTTE-VVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMA ::::..:: .. .: :.::.::: . .: . . : :::..::. :..:: ::.: XP_005 ERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVA 130 140 150 160 170 180 240 250 260 270 280 290 pF1KB5 GILLGILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN ::..:: : :..:. :. .. .: . XP_005 GIFIGIALLQIFGICLAQNLVSDIEAVRASW 190 200 210 294 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:15:22 2016 done: Sat Nov 5 06:15:23 2016 Total Scan time: 6.100 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]