Result of FASTA (omim) for pF1KB5014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5014, 417 aa
  1>>>pF1KB5014 417 - 417 aa - 417 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.7266+/-0.000443; mu= -2.0858+/- 0.028
 mean_var=327.9992+/-65.459, 0's: 0 Z-trim(120.8): 12  B-trim: 292 in 1/54
 Lambda= 0.070817
 statistics sampled from 36481 (36498) to 36481 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.428), width:  16
 Scan time:  9.240

The best scores are:                                      opt bits E(85289)
NP_004334 (OMIM: 109091,187950,254450) calreticuli ( 417) 2915 311.5 2.5e-84
NP_659483 (OMIM: 611414,613875) calreticulin-3 pre ( 384)  951 110.8   6e-24
NP_001737 (OMIM: 114217) calnexin precursor [Homo  ( 592)  472 62.1 4.4e-09
NP_001019820 (OMIM: 114217) calnexin precursor [Ho ( 592)  472 62.1 4.4e-09
XP_011532967 (OMIM: 114217) PREDICTED: calnexin is ( 592)  472 62.1 4.4e-09
XP_011532966 (OMIM: 114217) PREDICTED: calnexin is ( 646)  472 62.1 4.6e-09
NP_004353 (OMIM: 601858) calmegin precursor [Homo  ( 610)  419 56.7 1.9e-07
NP_001124147 (OMIM: 601858) calmegin precursor [Ho ( 610)  419 56.7 1.9e-07


>>NP_004334 (OMIM: 109091,187950,254450) calreticulin pr  (417 aa)
 initn: 2915 init1: 2915 opt: 2915  Z-score: 1634.9  bits: 311.5 E(85289): 2.5e-84
Smith-Waterman score: 2915; 100.0% identity (100.0% similar) in 417 aa overlap (1-417:1-417)

               10        20        30        40        50        60
pF1KB5 MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 EKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 TYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 HIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 PDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK
              310       320       330       340       350       360

              370       380       390       400       410       
pF1KB5 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
              370       380       390       400       410       

>>NP_659483 (OMIM: 611414,613875) calreticulin-3 precurs  (384 aa)
 initn: 1289 init1: 878 opt: 951  Z-score: 550.9  bits: 110.8 E(85289): 6e-24
Smith-Waterman score: 1312; 52.4% identity (76.8% similar) in 370 aa overlap (14-383:14-362)

               10        20        30        40        50        60
pF1KB5 MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDE
                    : ::  .:::.:.::::. : .::..: . : ::.: :::::::: .
NP_659 MARALVQLWAICMLRVALATVYFQEEFLDGEHWRNRWLQSTNDSRFGHFRLSSGKFYGHK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 EKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT
       ::::::::.:..::::.:: :.::::::.:::.:.::::::..::::::.:.:: ..:: 
NP_659 EKDKGLQTTQNGRFYAISARFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPADIDQK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDN
       ...: :.: :::::::::   ::::::...:.:    .: :::: : ::::::::.::: 
NP_659 NLNGKSQYYIMFGPDICGFDIKKVHVILHFKNKYHENKKLIRCKVDGFTHLYTLILRPDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 TYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPE
       .:.::::....::::.: ::..   ::  .:  ::  :: :..:     :.: .::.:  
NP_659 SYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESK--DW-EQTK-----DNKAQDWEK--
              190       200       210          220            230  

              250       260       270       280       290       300
pF1KB5 HIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYS
       :. : ...:  ::. ..::.:  :..:.: :.   ::. :    .: .:.: .. : .: 
NP_659 HFLDASTSKQSDWNGDLDGDWPAPMLQKPPYQDGLKPEGI----HKDVWLHRKMKNTDYL
              240       250       260       270           280      

              310       320       330       340       350       360
pF1KB5 PDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK
        . ..  ..:.:..::.::::.:::::::::::.:: ::..::. ::: ::. :..:   
NP_659 TQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPEREM---
        290       300       310       320       330       340      

              370       380       390       400       410       
pF1KB5 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
           . .. .:: :: .:::: :                                  
NP_659 ----DAIQAKEEMKKAREEEEEELLSGKINRHEHYFNQFHRRNEL            
               350       360       370       380                

>>NP_001737 (OMIM: 114217) calnexin precursor [Homo sapi  (592 aa)
 initn: 494 init1: 326 opt: 472  Z-score: 284.1  bits: 62.1 E(85289): 4.4e-09
Smith-Waterman score: 904; 36.5% identity (57.8% similar) in 479 aa overlap (32-408:78-555)

              10        20        30        40          50         
pF1KB5 LLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDF--GKFVLSSGKFYGD
                                     :  : :: :: :.:    ...  .::.  .
NP_001 DTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVE
        50        60        70        80        90       100       

      60              70        80         90       100       110  
pF1KB5 EEK------DKGLQTSQDARFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKL
       : :      ::::   . :. .:.::.. .::    . :.::. :. ...:.:::.::::
NP_001 EMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKL
       110       120       130       140       150       160       

              120       130       140       150       160          
pF1KB5 FPNS--LDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCK------
       . ..  :.  ..:  . :.:::::: ::   : .: :: .:. .. : .. . :      
NP_001 LSKTPELNLDQFHDKTPYTIMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADL
       170       180       190        200       210       220      

              170       180       190       200         210        
pF1KB5 ----DDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWD--FLPPKKIKDPDASKPED
            :. :::::::. :::..:. .:.: :.::.: .:      : ..:.::.  ::::
NP_001 KTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPED
        230       240       250       260       270       280      

      220       230                            240       250       
pF1KB5 WDERAKIDDPTDSKPEDWDK---------------------PEHIPDPDAKKPEDWDEEM
       :::: :: ::   ::.:::.                     ::..:::::.:::::::.:
NP_001 WDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDM
        290       300       310       320       330       340      

       260                          270       280       290        
pF1KB5 DGEWE-P------------------PVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPE
       ::::: :                  :::.::.:::.::: .::::.:.: :   .: ::.
NP_001 DGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPD
        350       360       370       380       390       400      

      300       310       320       330       340       350        
pF1KB5 YSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEK---
       .  :   . .  :...::.::.. :  .::::.:  :.  .....:. ::. :::.    
NP_001 FFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAE
        410       420       430       440       450       460      

              360                             370               380
pF1KB5 -----QMKDKQDEEQRL----------------------KEEEEDKKRKE--------EE
            :: .  .:.  :                      :..    . :.        .:
NP_001 PGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKE
        470       480       490       500       510       520      

              390        400       410                             
pF1KB5 EAEDKEDDEDK-DEDEEDEEDKEEDEEEDVPGQAKDEL                      
       : :.::...:: ::.:: ::  :: .. :                               
NP_001 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRN
        530       540       550       560       570       580      

>>NP_001019820 (OMIM: 114217) calnexin precursor [Homo s  (592 aa)
 initn: 494 init1: 326 opt: 472  Z-score: 284.1  bits: 62.1 E(85289): 4.4e-09
Smith-Waterman score: 904; 36.5% identity (57.8% similar) in 479 aa overlap (32-408:78-555)

              10        20        30        40          50         
pF1KB5 LLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDF--GKFVLSSGKFYGD
                                     :  : :: :: :.:    ...  .::.  .
NP_001 DTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVE
        50        60        70        80        90       100       

      60              70        80         90       100       110  
pF1KB5 EEK------DKGLQTSQDARFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKL
       : :      ::::   . :. .:.::.. .::    . :.::. :. ...:.:::.::::
NP_001 EMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKL
       110       120       130       140       150       160       

              120       130       140       150       160          
pF1KB5 FPNS--LDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCK------
       . ..  :.  ..:  . :.:::::: ::   : .: :: .:. .. : .. . :      
NP_001 LSKTPELNLDQFHDKTPYTIMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADL
       170       180       190        200       210       220      

              170       180       190       200         210        
pF1KB5 ----DDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWD--FLPPKKIKDPDASKPED
            :. :::::::. :::..:. .:.: :.::.: .:      : ..:.::.  ::::
NP_001 KTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPED
        230       240       250       260       270       280      

      220       230                            240       250       
pF1KB5 WDERAKIDDPTDSKPEDWDK---------------------PEHIPDPDAKKPEDWDEEM
       :::: :: ::   ::.:::.                     ::..:::::.:::::::.:
NP_001 WDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDM
        290       300       310       320       330       340      

       260                          270       280       290        
pF1KB5 DGEWE-P------------------PVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPE
       ::::: :                  :::.::.:::.::: .::::.:.: :   .: ::.
NP_001 DGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPD
        350       360       370       380       390       400      

      300       310       320       330       340       350        
pF1KB5 YSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEK---
       .  :   . .  :...::.::.. :  .::::.:  :.  .....:. ::. :::.    
NP_001 FFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAE
        410       420       430       440       450       460      

              360                             370               380
pF1KB5 -----QMKDKQDEEQRL----------------------KEEEEDKKRKE--------EE
            :: .  .:.  :                      :..    . :.        .:
NP_001 PGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKE
        470       480       490       500       510       520      

              390        400       410                             
pF1KB5 EAEDKEDDEDK-DEDEEDEEDKEEDEEEDVPGQAKDEL                      
       : :.::...:: ::.:: ::  :: .. :                               
NP_001 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRN
        530       540       550       560       570       580      

>>XP_011532967 (OMIM: 114217) PREDICTED: calnexin isofor  (592 aa)
 initn: 494 init1: 326 opt: 472  Z-score: 284.1  bits: 62.1 E(85289): 4.4e-09
Smith-Waterman score: 904; 36.5% identity (57.8% similar) in 479 aa overlap (32-408:78-555)

              10        20        30        40          50         
pF1KB5 LLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDF--GKFVLSSGKFYGD
                                     :  : :: :: :.:    ...  .::.  .
XP_011 DTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVE
        50        60        70        80        90       100       

      60              70        80         90       100       110  
pF1KB5 EEK------DKGLQTSQDARFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKL
       : :      ::::   . :. .:.::.. .::    . :.::. :. ...:.:::.::::
XP_011 EMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKL
       110       120       130       140       150       160       

              120       130       140       150       160          
pF1KB5 FPNS--LDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCK------
       . ..  :.  ..:  . :.:::::: ::   : .: :: .:. .. : .. . :      
XP_011 LSKTPELNLDQFHDKTPYTIMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADL
       170       180       190        200       210       220      

              170       180       190       200         210        
pF1KB5 ----DDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWD--FLPPKKIKDPDASKPED
            :. :::::::. :::..:. .:.: :.::.: .:      : ..:.::.  ::::
XP_011 KTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPED
        230       240       250       260       270       280      

      220       230                            240       250       
pF1KB5 WDERAKIDDPTDSKPEDWDK---------------------PEHIPDPDAKKPEDWDEEM
       :::: :: ::   ::.:::.                     ::..:::::.:::::::.:
XP_011 WDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDM
        290       300       310       320       330       340      

       260                          270       280       290        
pF1KB5 DGEWE-P------------------PVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPE
       ::::: :                  :::.::.:::.::: .::::.:.: :   .: ::.
XP_011 DGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPD
        350       360       370       380       390       400      

      300       310       320       330       340       350        
pF1KB5 YSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEK---
       .  :   . .  :...::.::.. :  .::::.:  :.  .....:. ::. :::.    
XP_011 FFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAE
        410       420       430       440       450       460      

              360                             370               380
pF1KB5 -----QMKDKQDEEQRL----------------------KEEEEDKKRKE--------EE
            :: .  .:.  :                      :..    . :.        .:
XP_011 PGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKE
        470       480       490       500       510       520      

              390        400       410                             
pF1KB5 EAEDKEDDEDK-DEDEEDEEDKEEDEEEDVPGQAKDEL                      
       : :.::...:: ::.:: ::  :: .. :                               
XP_011 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRN
        530       540       550       560       570       580      

>>XP_011532966 (OMIM: 114217) PREDICTED: calnexin isofor  (646 aa)
 initn: 494 init1: 326 opt: 472  Z-score: 283.6  bits: 62.1 E(85289): 4.6e-09
Smith-Waterman score: 904; 36.5% identity (57.8% similar) in 479 aa overlap (32-408:132-609)

              10        20        30        40          50         
pF1KB5 LLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDF--GKFVLSSGKFYGD
                                     :  : :: :: :.:    ...  .::.  .
XP_011 DTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVE
             110       120       130       140       150       160 

      60              70        80         90       100       110  
pF1KB5 EEK------DKGLQTSQDARFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKL
       : :      ::::   . :. .:.::.. .::    . :.::. :. ...:.:::.::::
XP_011 EMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKL
             170       180       190       200       210       220 

              120       130       140       150       160          
pF1KB5 FPNS--LDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCK------
       . ..  :.  ..:  . :.:::::: ::   : .: :: .:. .. : .. . :      
XP_011 LSKTPELNLDQFHDKTPYTIMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADL
             230       240       250        260       270       280

              170       180       190       200         210        
pF1KB5 ----DDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWD--FLPPKKIKDPDASKPED
            :. :::::::. :::..:. .:.: :.::.: .:      : ..:.::.  ::::
XP_011 KTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPED
              290       300       310       320       330       340

      220       230                            240       250       
pF1KB5 WDERAKIDDPTDSKPEDWDK---------------------PEHIPDPDAKKPEDWDEEM
       :::: :: ::   ::.:::.                     ::..:::::.:::::::.:
XP_011 WDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDM
              350       360       370       380       390       400

       260                          270       280       290        
pF1KB5 DGEWE-P------------------PVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPE
       ::::: :                  :::.::.:::.::: .::::.:.: :   .: ::.
XP_011 DGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPD
              410       420       430       440       450       460

      300       310       320       330       340       350        
pF1KB5 YSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEK---
       .  :   . .  :...::.::.. :  .::::.:  :.  .....:. ::. :::.    
XP_011 FFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAE
              470       480       490       500       510       520

              360                             370               380
pF1KB5 -----QMKDKQDEEQRL----------------------KEEEEDKKRKE--------EE
            :: .  .:.  :                      :..    . :.        .:
XP_011 PGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKE
              530       540       550       560       570       580

              390        400       410                             
pF1KB5 EAEDKEDDEDK-DEDEEDEEDKEEDEEEDVPGQAKDEL                      
       : :.::...:: ::.:: ::  :: .. :                               
XP_011 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRN
              590       600       610       620       630       640

>>NP_004353 (OMIM: 601858) calmegin precursor [Homo sapi  (610 aa)
 initn: 944 init1: 342 opt: 419  Z-score: 254.7  bits: 56.7 E(85289): 1.9e-07
Smith-Waterman score: 843; 38.5% identity (62.6% similar) in 377 aa overlap (32-347:69-444)

              10        20        30        40         50          
pF1KB5 LLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESK-HKSDFGKFV-LSSGKFYGD
                                     :  . :. :: .:.:. . . . .:..  .
NP_004 DVNESELSSEIKYKTPQPIGEVYFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIE
       40        50        60        70        80        90        

      60              70        80         90       100       110  
pF1KB5 EEK------DKGLQTSQDARFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKL
       : :      :.::  .. :. .:.:: . .::    . :.::. :. ...:::::.:.::
NP_004 ELKENQVPGDRGLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKL
      100       110       120       130       140       150        

            120         130       140       150         160        
pF1KB5 FPNSLDQT--DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKN--VLINKDIRCKD---
       . .. :    ...  . : :::::: ::   : .: :: .:  .  :. .:  .  :   
NP_004 LADTDDLILENFYDKTSYIIMFGPDKCGEDYK-LHFIFRHKHPKTGVFEEKHAKPPDVDL
      160       170       180       190        200       210       

              170       180       190       200         210        
pF1KB5 -----DEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDW--DFLPPKKIKDPDASKPED
            :. ::::::.. ::.:.:: .:.. :..::: .:    . :::.:.::. .:::.
NP_004 KKFFTDRKTHLYTLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEE
       220       230       240       250       260       270       

      220       230                            240       250       
pF1KB5 WDERAKIDDPTDSKPEDWDK---------------------PEHIPDPDAKKPEDWDEEM
       ::::::: ::.  ::::::.                     :. ::::.:.::.::.:. 
NP_004 WDERAKIPDPSAVKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDT
       280       290       300       310       320       330       

       260       270          280       290       300              
pF1KB5 DGEWEPPVIQNPEYK---GEWKPRQIDNPDYKGTWIHPEIDNPEYS--------PDPSIY
       ::::: : : ::  .   ::::: .:::: :::.:  : .:::.:.        :.:. .
NP_004 DGEWEAPQILNPACRIGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYF
       340       350       360       370       380       390       

        310             320       330       340       350       360
pF1KB5 AYDN------FGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK
         :.      :..:::.::.. :   ::::.: ...  :.... . :             
NP_004 EDDHPFLLTSFSALGLELWSMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPG
       400       410       420       430       440       450       

              370       380       390       400       410          
pF1KB5 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL   
                                                                   
NP_004 VLKQLMAAAEGHPWLWLIYLVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKG
       460       470       480       490       500       510       

>>NP_001124147 (OMIM: 601858) calmegin precursor [Homo s  (610 aa)
 initn: 944 init1: 342 opt: 419  Z-score: 254.7  bits: 56.7 E(85289): 1.9e-07
Smith-Waterman score: 843; 38.5% identity (62.6% similar) in 377 aa overlap (32-347:69-444)

              10        20        30        40         50          
pF1KB5 LLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESK-HKSDFGKFV-LSSGKFYGD
                                     :  . :. :: .:.:. . . . .:..  .
NP_001 DVNESELSSEIKYKTPQPIGEVYFAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIE
       40        50        60        70        80        90        

      60              70        80         90       100       110  
pF1KB5 EEK------DKGLQTSQDARFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKL
       : :      :.::  .. :. .:.:: . .::    . :.::. :. ...:::::.:.::
NP_001 ELKENQVPGDRGLVLKSRAKHHAISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKL
      100       110       120       130       140       150        

            120         130       140       150         160        
pF1KB5 FPNSLDQT--DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKN--VLINKDIRCKD---
       . .. :    ...  . : :::::: ::   : .: :: .:  .  :. .:  .  :   
NP_001 LADTDDLILENFYDKTSYIIMFGPDKCGEDYK-LHFIFRHKHPKTGVFEEKHAKPPDVDL
      160       170       180       190        200       210       

              170       180       190       200         210        
pF1KB5 -----DEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDW--DFLPPKKIKDPDASKPED
            :. ::::::.. ::.:.:: .:.. :..::: .:    . :::.:.::. .:::.
NP_001 KKFFTDRKTHLYTLVMNPDDTFEVLVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEE
       220       230       240       250       260       270       

      220       230                            240       250       
pF1KB5 WDERAKIDDPTDSKPEDWDK---------------------PEHIPDPDAKKPEDWDEEM
       ::::::: ::.  ::::::.                     :. ::::.:.::.::.:. 
NP_001 WDERAKIPDPSAVKPEDWDESEPAQIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDT
       280       290       300       310       320       330       

       260       270          280       290       300              
pF1KB5 DGEWEPPVIQNPEYK---GEWKPRQIDNPDYKGTWIHPEIDNPEYS--------PDPSIY
       ::::: : : ::  .   ::::: .:::: :::.:  : .:::.:.        :.:. .
NP_001 DGEWEAPQILNPACRIGCGEWKPPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYF
       340       350       360       370       380       390       

        310             320       330       340       350       360
pF1KB5 AYDN------FGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK
         :.      :..:::.::.. :   ::::.: ...  :.... . :             
NP_001 EDDHPFLLTSFSALGLELWSMTSDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPG
       400       410       420       430       440       450       

              370       380       390       400       410          
pF1KB5 QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL   
                                                                   
NP_001 VLKQLMAAAEGHPWLWLIYLVTAGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKG
       460       470       480       490       500       510       




417 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 15:46:03 2016 done: Thu Nov  3 15:46:05 2016
 Total Scan time:  9.240 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com