FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5016, 677 aa
  1>>>pF1KB5016 677 - 677 aa - 677 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.0012+/-0.000485; mu= -6.9449+/- 0.030
 mean_var=342.3690+/-69.858, 0's: 0 Z-trim(119.2): 41  B-trim: 254 in 1/56
 Lambda= 0.069315
 statistics sampled from 32892 (32933) to 32892 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.386), width:  16
 Scan time: 12.560

The best scores are:                                      opt bits E(85289)
NP_001810 (OMIM: 118920) secretogranin-1 precursor ( 677) 4567 471.2 5.4e-132
NP_001030025 (OMIM: 300029,300455,300834,304020,31 (1152)  346 49.3 9.5e-05


>>NP_001810 (OMIM: 118920) secretogranin-1 precursor [Ho  (677 aa)
 initn: 4567 init1: 4567 opt: 4567  Z-score: 2490.6  bits: 471.2 E(85289): 5.4e-132
Smith-Waterman score: 4567; 99.3% identity (100.0% similar) in 677 aa overlap (1-677:1-677)

               10        20        30        40        50        60
pF1KB5 MQPTLLLSLLGAVGLAAVNSMPVDNRNHNEGMVTRCIIEVLSNALSKSSAPPITPECRQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQPTLLLSLLGAVGLAAVNSMPVDNRNHNEGMVTRCIIEVLSNALSKSSAPPITPECRQV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 LKTSRKDVKDKETTENENTKFEVRLLRDPADATEAHESSSRGEAGAPGEEDIQGPTKADT
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_001 LKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGPTKADT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGEQGE
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 EKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGERGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 DSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQESG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 EEAGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLP
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EETGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSLP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 SEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQGPEDLEWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_001 SEEKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 RYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGHHHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_001 RYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGKGRHHR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 GRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGEEGAP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 GKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHFERRD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB5 NMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB5 YDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDRVAQLDQLLHYRKKSAEFPDFYDSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLA
              610       620       630       640       650       660

              670       
pF1KB5 AMDLELQKIAEKFSQRG
       :::::::::::::::::
NP_001 AMDLELQKIAEKFSQRG
              670       

>>NP_001030025 (OMIM: 300029,300455,300834,304020,312610  (1152 aa)
 initn: 302 init1: 176 opt: 346  Z-score: 206.3  bits: 49.3 E(85289): 9.5e-05
Smith-Waterman score: 382; 25.9% identity (59.2% similar) in 436 aa overlap (94-522:676-1085)

            70        80        90       100       110       120   
pF1KB5 SRKDVKDKETTENENTKFEVRLLRDPADATEAHESSSRGEAGAPGEEDIQGPTKADTEKW
                                     .......:::   ::: . .    :. :.:
NP_001 EAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKE---LAEKEEW
         650       660       670       680       690          700  

           130       140       150           160       170         
pF1KB5 AEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSE----KSQREDEEEEEGENYQKGEQG
        .  :. .:. .. :      .... :  . .:.:    ...::.:::.:::. ..:: :
NP_001 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGE-G
            710       720       730       740       750       760  

     180       190       200       210       220       230         
pF1KB5 EDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQES
       :.   :.. ::         .:::.     :::   .   .. :. .:.:..: . ..:.
NP_001 EEVEGEREKEE---------GERKKEERAGKEEKGEEEGDQGEGE-EEETEGRGEEKEEG
             770                780       790        800       810 

     240       250       260       270       280       290         
pF1KB5 GEEAGSQENHPQESKGQPRSQEESEEGEEDATSEVDKRRTRPRHHHGRSRPDRSSQGGSL
       ::  :..    .:.::. . .::  ::::.  .: .... . ....:... .. .. :  
NP_001 GEVEGGE---VEEGKGEREEEEEEGEGEEEE-GEGEEEEGEGEEEEGEGKGEEEGEEGEG
                820       830        840       850       860       

     300        310       320       330       340        350       
pF1KB5 PSE-EKGHPQEESEESNVSMASLGEKRDHHSTHYRASEEEPE-YGEEIKGYPGVQGPEDL
         : :.:. . : ::..      :: . ..      .::: :  ::: .:    .:  . 
NP_001 EEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG----EGKGEE
       870       880       890       900       910           920   

       360       370       380       390       400       410       
pF1KB5 EWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLE-PGKG
       : :. .:.: ::    . .. :.  ::.. .. . :  . ..: :::  : .: :  :.:
NP_001 EGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEE--EEGEGEGEEEGEGEGEEGEGEG
           930       940       950         960       970       980 

        420       430       440       450       460       470      
pF1KB5 HHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQENQMDKARRHPQGAWKELDRNYLNYGE
       ....:.:   .     . .:: .   ::. . .:..  ... . .:   : . .  .  :
NP_001 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE
             990      1000      1010      1020      1030      1040 

        480       490       500       510       520       530      
pF1KB5 EGAPGKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGELFNPYYDPLQWKSSHF
       ::   . ...:. .....:::: . .. .:.     :.... :: .              
NP_001 EGE--EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGK
              1050      1060      1070      1080      1090         

        540       550       560       570       580       590      
pF1KB5 ERRDNMNDNFLEGEEENELTLNEKNFFPEYNYDWWEKKPFSEDVNWGYEKRNLARVPKLD
                                                                   
NP_001 HKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPSGSKKFWNNVLPHYLELK       
    1100      1110      1120      1130      1140      1150         




677 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:12:34 2016 done: Thu Nov  3 22:12:36 2016
 Total Scan time: 12.560 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]