FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5017, 338 aa 1>>>pF1KB5017 338 - 338 aa - 338 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.9588+/-0.000752; mu= 4.5770+/- 0.045 mean_var=154.3972+/-31.327, 0's: 0 Z-trim(114.1): 10 B-trim: 0 in 0/52 Lambda= 0.103218 statistics sampled from 14724 (14731) to 14724 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.453), width: 16 Scan time: 2.940 The best scores are: opt bits E(32554) CCDS9791.1 ZFP36L1 gene_id:677|Hs108|chr14 ( 338) 2302 354.0 1e-97 CCDS1811.1 ZFP36L2 gene_id:678|Hs108|chr2 ( 494) 674 111.7 1.3e-24 CCDS12534.2 ZFP36 gene_id:7538|Hs108|chr19 ( 332) 509 87.0 2.4e-17 >>CCDS9791.1 ZFP36L1 gene_id:677|Hs108|chr14 (338 aa) initn: 2302 init1: 2302 opt: 2302 Z-score: 1867.8 bits: 354.0 E(32554): 1e-97 Smith-Waterman score: 2302; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KB5 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 KFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 RPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 RPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 ERRALAGARDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 ERRALAGARDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS97 PTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLS 250 260 270 280 290 300 310 320 330 pF1KB5 DQEGYLSSSSSSHSGSDSPTLDNSRRLPIFSRLSISDD :::::::::::::::::::::::::::::::::::::: CCDS97 DQEGYLSSSSSSHSGSDSPTLDNSRRLPIFSRLSISDD 310 320 330 >>CCDS1811.1 ZFP36L2 gene_id:678|Hs108|chr2 (494 aa) initn: 941 init1: 552 opt: 674 Z-score: 555.2 bits: 111.7 E(32554): 1.3e-24 Smith-Waterman score: 737; 49.8% identity (64.2% similar) in 285 aa overlap (11-230:10-290) 10 20 30 40 50 pF1KB5 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGG--------GFPRR .:. . ::: .: : : . .::.::::::... :: :: CCDS18 MSTTLLSAFYDV-DFLCKTEKSL---ANLNLNNMLDKKAVGTPVAAAPSSGFAPGFLRR 10 20 30 40 50 60 70 80 pF1KB5 HSVT--------LPSS-----KF----HQNQLLSSLKGEPA-------P------ALSSR ::.. :: :: . .. :. : :. : :: .. CCDS18 HSASNLHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNK 60 70 80 90 100 110 90 100 110 120 130 pF1KB5 DSRFRDRSFSEGGER---LLPTQKQP---GGGQVNSSRYKTELCRPFEENGACKYGDKCQ ...::::::::.:.: :: :.: ::.:.::.::::::::::::.:.::::.::: CCDS18 ENKFRDRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQ 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB5 FAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRAL--AGAR-DLSA ::::.::::::::::::::::::::::::::::::::::::::.::: .:: :: : CCDS18 FAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRA 180 190 200 210 220 230 200 210 220 230 pF1KB5 --------------DRPRLQHSFSFAGFPSA----AATAAATGLLDSPTSITPPPILSAD ::.:.::.::.::::. . . ::::::: :::: CCDS18 FGTRDALHLGFPREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSS 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB5 DLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSP CCDS18 ASSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSS 300 310 320 330 340 350 >>CCDS12534.2 ZFP36 gene_id:7538|Hs108|chr19 (332 aa) initn: 494 init1: 377 opt: 509 Z-score: 425.0 bits: 87.0 E(32554): 2.4e-17 Smith-Waterman score: 530; 40.2% identity (56.0% similar) in 266 aa overlap (95-337:90-332) 70 80 90 100 110 120 pF1KB5 NQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELCRPFE : .: :. .: . ... ::::::::: : CCDS12 LPGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 ENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRA :.: :.:: :::::::. :::. .::::::::::. :. : :::: ::::::: : : CCDS12 ESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLA 120 130 140 150 160 170 190 200 210 220 230 pF1KB5 LAGARDLSADRPRLQHSFSFAGFPSAAATAAAT-GLLD--------SPTSITPPP---IL : : :..:.::.:.::. :. :: ::.: ::: : CCDS12 APG------HPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 SADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSP : . . ..: : . .: :. : :: : : CCDS12 SPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGG-----LVRT----------- 240 250 260 270 300 310 320 330 pF1KB5 PSPQDSLSDQEGYLSSSSSSHSGSDSPTLDNS-----------RRLPIFSRLSISDD :: :. :: . : .::.:: .:::::... . ::::::.:.:.:. CCDS12 PSVQSLGSDPDEY-ASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE 280 290 300 310 320 330 338 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:46:35 2016 done: Thu Nov 3 15:46:35 2016 Total Scan time: 2.940 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]