FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5018, 362 aa 1>>>pF1KB5018 362 - 362 aa - 362 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0345+/-0.000896; mu= -2.3369+/- 0.055 mean_var=247.2334+/-50.124, 0's: 0 Z-trim(114.9): 10 B-trim: 0 in 0/54 Lambda= 0.081568 statistics sampled from 15477 (15484) to 15477 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.476), width: 16 Scan time: 3.380 The best scores are: opt bits E(32554) CCDS59358.1 RAD23A gene_id:5886|Hs108|chr19 ( 362) 2344 288.1 8.2e-78 CCDS12289.1 RAD23A gene_id:5886|Hs108|chr19 ( 363) 2332 286.6 2.2e-77 CCDS59357.1 RAD23A gene_id:5886|Hs108|chr19 ( 308) 1731 215.9 3.7e-56 CCDS59138.1 RAD23B gene_id:5887|Hs108|chr9 ( 337) 694 93.9 2.2e-19 CCDS6769.1 RAD23B gene_id:5887|Hs108|chr9 ( 409) 467 67.2 2.8e-11 >>CCDS59358.1 RAD23A gene_id:5886|Hs108|chr19 (362 aa) initn: 2344 init1: 2344 opt: 2344 Z-score: 1510.4 bits: 288.1 E(32554): 8.2e-78 Smith-Waterman score: 2344; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAGENPLEFLRDQPQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAGENPLEFLRDQPQF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 QNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 QNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGEV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 GAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 GAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFD 310 320 330 340 350 360 pF1KB5 DE :: CCDS59 DE >>CCDS12289.1 RAD23A gene_id:5886|Hs108|chr19 (363 aa) initn: 1444 init1: 1444 opt: 2332 Z-score: 1502.8 bits: 286.6 E(32554): 2.2e-77 Smith-Waterman score: 2332; 99.7% identity (99.7% similar) in 363 aa overlap (1-362:1-363) 10 20 30 40 50 60 pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEA-GENPLEFLRDQPQ :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: CCDS12 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 FQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 FQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 VGAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VGAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNF 310 320 330 340 350 360 360 pF1KB5 DDE ::: CCDS12 DDE >>CCDS59357.1 RAD23A gene_id:5886|Hs108|chr19 (308 aa) initn: 1681 init1: 1444 opt: 1731 Z-score: 1121.6 bits: 215.9 E(32554): 3.7e-56 Smith-Waterman score: 1851; 84.6% identity (84.6% similar) in 363 aa overlap (1-362:1-308) 10 20 30 40 50 60 pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 IRDYRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAARE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 DKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEA-GENPLEFLRDQPQ :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: CCDS59 VAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQVSEQPATEAAGENPLEFLRDQPQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 FQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE ::::::::::::::::::::::::::::::: CCDS59 FQNMRQVIQQNPALLPALLQQLGQENPQLLQ----------------------------- 250 260 270 300 310 320 330 340 350 pF1KB5 VGAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNF :::::::::::::::::::::::::::::::::: CCDS59 --------------------------LKALGFPESLVIQAYFACEKNENLAANFLLSQNF 280 290 300 360 pF1KB5 DDE ::: CCDS59 DDE >>CCDS59138.1 RAD23B gene_id:5887|Hs108|chr9 (337 aa) initn: 1012 init1: 360 opt: 694 Z-score: 461.5 bits: 93.9 E(32554): 2.2e-19 Smith-Waterman score: 1020; 54.1% identity (72.9% similar) in 340 aa overlap (48-362:1-337) 20 30 40 50 60 70 pF1KB5 RMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVPIRDYR-IDEKNFVVVMV .. : .: .: . .. .:. CCDS59 MVTKPKAVSTPAPATTQQSAPASTTAVTSS 10 20 30 80 90 100 110 120 130 pF1KB5 TKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPA-AREDKSPSEESAPTTSPE : : ..:. . : .::..: : : :: ... :.: :: : ....:.:. : : CCDS59 TTTTVAQAPTPVPALAPTSTPASIT---PASATASSEPAPASAAKQEKPAEKPAETPVAT 40 50 60 70 80 140 150 160 170 180 190 pF1KB5 SVSGSVPSSGSSGRE---EDAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPH : ... .::.:.: :::.:.::::. ::.:.:::::::::::.:.::::::.::: CCDS59 SPTATDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPD 90 100 110 120 130 140 200 210 220 230 pF1KB5 RAVEYLLTGIPGSPE------PEH----GSVQESQVSEQPATE--------AGENPLEFL ::::::: ::::. : : . :. : : :. :: .: .::::: CCDS59 RAVEYLLMGIPGDRESQAVVDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFL 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 RDQPQFQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADIS :.:::::.:::.:::::.::::::::.:.::::::::::.:::.:::::::: : . . CCDS59 RNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQG 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 DVEGE-VGAIGEEAP-QMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAAN : :.:.: . .::::::::::::::::::::::::.:::::::::::::::::: CCDS59 GGGGGGSGGIAEAGSGHMNYIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAAN 270 280 290 300 310 320 360 pF1KB5 FLLSQNFDDE :::.::::.. CCDS59 FLLQQNFDED 330 >>CCDS6769.1 RAD23B gene_id:5887|Hs108|chr9 (409 aa) initn: 1398 init1: 400 opt: 467 Z-score: 315.9 bits: 67.2 E(32554): 2.8e-11 Smith-Waterman score: 1261; 58.5% identity (74.9% similar) in 390 aa overlap (5-345:3-392) 10 20 30 40 50 60 pF1KB5 MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVP .:::::::::::: ..:.::::.::::::.:::.:::::::::::::::::.::. CCDS67 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTA 10 20 30 40 50 70 80 90 pF1KB5 IRDYRIDEKNFVVVMVTKTKA----GQGT---SAP-----------------PEASPTAA ...:.::::::::::::: :: . .: ::: : :. : CCDS67 LKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALA 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB5 PESS-TSFPPAPTSGMSHPPPA-AREDKSPSEESAPTTSPESVSGSVPSSGSSGRE---E : :. .:. :: ... :.: :: : ....:.:. : : : ... .::.:.: : CCDS67 PTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFE 120 130 140 150 160 170 160 170 180 190 200 pF1KB5 DAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPE---- ::.:.::::. ::.:.:::::::::::.:.::::::.::: ::::::: ::::. : CCDS67 DATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRAVEYLLMGIPGDRESQAV 180 190 200 210 220 230 210 220 230 240 250 pF1KB5 --PEH----GSVQESQVSEQPATE--------AGENPLEFLRDQPQFQNMRQVIQQNPAL : . :. : : :. :: .: .::::::.:::::.:::.:::::.: CCDS67 VDPPQAASTGAPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSL 240 250 260 270 280 290 260 270 280 290 300 310 pF1KB5 LPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGE-VGAIGEEAP-QMN :::::::.:.::::::::::.:::.:::::::: : . . : :.:.: . .:: CCDS67 LPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMN 300 310 320 330 340 350 320 330 340 350 360 pF1KB5 YIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFDDE ::::::::::::::::::::::.::::::::::: CCDS67 YIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED 360 370 380 390 400 362 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:21:09 2016 done: Fri Nov 4 03:21:09 2016 Total Scan time: 3.380 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]