FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5019, 505 aa 1>>>pF1KB5019 505 - 505 aa - 505 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4839+/-0.000927; mu= 16.9636+/- 0.056 mean_var=69.4142+/-13.322, 0's: 0 Z-trim(105.1): 45 B-trim: 3 in 1/49 Lambda= 0.153940 statistics sampled from 8182 (8221) to 8182 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.253), width: 16 Scan time: 3.180 The best scores are: opt bits E(32554) CCDS10101.1 PDIA3 gene_id:2923|Hs108|chr15 ( 505) 3347 752.8 2.1e-217 CCDS5893.1 PDIA4 gene_id:9601|Hs108|chr7 ( 645) 1194 274.7 2.2e-73 CCDS42089.1 PDIA2 gene_id:64714|Hs108|chr16 ( 525) 722 169.8 6.7e-42 CCDS11787.1 P4HB gene_id:5034|Hs108|chr17 ( 508) 643 152.2 1.2e-36 CCDS10584.1 PDILT gene_id:204474|Hs108|chr16 ( 584) 372 92.1 1.8e-18 CCDS62853.1 PDIA6 gene_id:10130|Hs108|chr2 ( 445) 312 78.7 1.5e-14 CCDS62855.1 PDIA6 gene_id:10130|Hs108|chr2 ( 488) 312 78.7 1.6e-14 CCDS62854.1 PDIA6 gene_id:10130|Hs108|chr2 ( 492) 312 78.7 1.6e-14 CCDS1675.1 PDIA6 gene_id:10130|Hs108|chr2 ( 440) 310 78.2 2e-14 CCDS62852.1 PDIA6 gene_id:10130|Hs108|chr2 ( 437) 308 77.8 2.7e-14 CCDS32840.1 TMX3 gene_id:54495|Hs108|chr18 ( 454) 299 75.8 1.1e-13 CCDS4505.1 TXNDC5 gene_id:81567|Hs108|chr6 ( 432) 281 71.8 1.7e-12 CCDS3020.1 PDIA5 gene_id:10954|Hs108|chr3 ( 519) 257 66.5 8.1e-11 >>CCDS10101.1 PDIA3 gene_id:2923|Hs108|chr15 (505 aa) initn: 3347 init1: 3347 opt: 3347 Z-score: 4016.7 bits: 752.8 E(32554): 2.1e-217 Smith-Waterman score: 3347; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505) 10 20 30 40 50 60 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 ADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 NYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 EKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYL 430 440 450 460 470 480 490 500 pF1KB5 QREATNPPVIQEEKPKKKKKAQEDL ::::::::::::::::::::::::: CCDS10 QREATNPPVIQEEKPKKKKKAQEDL 490 500 >>CCDS5893.1 PDIA4 gene_id:9601|Hs108|chr7 (645 aa) initn: 824 init1: 400 opt: 1194 Z-score: 1430.9 bits: 274.7 E(32554): 2.2e-73 Smith-Waterman score: 1194; 42.1% identity (71.8% similar) in 478 aa overlap (28-493:180-644) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWC : :: .::. ..: : ..::::.:::: CCDS58 DYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVND---ADIILVEFYAPWC 150 160 170 180 190 200 60 70 80 90 100 110 pF1KB5 GHCKRLAPEYEAAATRLKG---IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA ::::.:::::: :: .:. .:::::: ::.:. ... ::::::::::: :. CCDS58 GHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYD- 210 220 230 240 250 260 120 130 140 150 160 170 pF1KB5 YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISD-KDASIVGFFDDSFSEAHSEFLK :.::: :::... .:.:: : . : .. ..:..: :. :.: : . :.... CCDS58 YNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQD 270 280 290 300 310 320 180 190 200 210 220 230 pF1KB5 AASNLRDNYRFAHTNVESLVNEYDDNGEG-IILFRPSHLTNKFEDKTVAYTEQKMTSGK- ::.:::..:.: :: . . .. ..: .....: .. .:.: .. . : :. . CCDS58 AANNLREDYKFHHT-FSTEIAKFLKVSQGQLVVMQPEKFQSKYEPRSHMMDVQGSTQDSA 330 340 350 360 370 380 240 250 260 270 280 pF1KB5 IKKFIQENIFGICPH--MTEDNKDLIQGKDLLIAYYDVDYEKNAKG-SNYWRNRVMMVAK :: :. . . . : ...: : . . :...::.::. . .. ...::..:. ::: CCDS58 IKDFVLKYALPLVGHRKVSNDAKRYTR-RPLVVVYYSVDFSFDYRAATQFWRSKVLEVAK 390 400 410 420 430 440 290 300 310 320 330 340 pF1KB5 KFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQ-EEFSRDGK : . .::.:... .. :..:.:: : .:: .:: .:.::.:. :::. : CCDS58 DF----PEYTFAIADEEDYAGEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSD-- 450 460 470 480 490 350 360 370 380 390 400 pF1KB5 ALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCG .:..:. . :.:: .::.:.:..: :::::::...:: :: . .::::::::::::: CCDS58 TLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCG 500 510 520 530 540 550 410 420 430 440 450 460 pF1KB5 HCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSP-YEVRGFPTIYFSPANKKLNPKK :::.::: :. :..: . . ..:::::::::::::: :.:.:::::::.:.. : :: : CCDS58 HCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNPVK 560 570 580 590 600 610 470 480 490 500 pF1KB5 YEGG-RELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL .::: :.: . ......::. .:: CCDS58 FEGGDRDLEHLSKFIEEHATKLSRTKEEL 620 630 640 >-- initn: 303 init1: 152 opt: 315 Z-score: 375.9 bits: 79.4 E(32554): 1.3e-14 Smith-Waterman score: 315; 42.6% identity (71.3% similar) in 115 aa overlap (27-138:64-174) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPW :: :.: ::.. ..: . .:.::.::: CCDS58 RENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDT---VLLEFYAPW 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB5 CGHCKRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG :::::..::::: :. :: .:.::.: :. . ... ::::::.::.. :. : CCDS58 CGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQ-AV 100 110 120 130 140 120 130 140 150 160 170 pF1KB5 AYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLK :.: :: . ::..... . : .: CCDS58 DYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHC 150 160 170 180 190 200 >>CCDS42089.1 PDIA2 gene_id:64714|Hs108|chr16 (525 aa) initn: 643 init1: 244 opt: 722 Z-score: 865.7 bits: 169.8 E(32554): 6.7e-42 Smith-Waterman score: 722; 30.1% identity (61.7% similar) in 465 aa overlap (48-501:62-508) 20 30 40 50 60 70 pF1KB5 AARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKG- .::::.:::::::. ::::: ::. : . CCDS42 EPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAE 40 50 60 70 80 90 80 90 100 110 120 130 pF1KB5 --IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQA .: ::::: :. . ...::. :::::.::.:... : ::: :.::. :.... CCDS42 SMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRV 100 110 120 130 140 150 140 150 160 170 180 190 pF1KB5 GPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESL ::... :. : . .:. .: ..:::.: .: . :: :.. : . :. :. : CCDS42 GPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALD-MTFGLTDRPRL 160 170 180 190 200 210 200 210 220 230 240 pF1KB5 VNEYDDNGEGIILFRPSHLTNKFEDKTVAYT---EQKMTSGKIKKF-IQENIFGICPHMT ... . . ..::. ::.. . . : . : ...: . ... . . CCDS42 FQQFGLTKDTVVLFK------KFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNS 220 230 240 250 260 250 260 270 280 290 300 pF1KB5 EDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFS . . .. .. .. . . ... . .: .: :. : .: CCDS42 QTSAKIFAAR--ILNHLLLFVNQTLAAHRELLAGFGEAAPRF--RGQVLFVVVDVAADNE 270 280 290 300 310 320 310 320 330 340 350 360 pF1KB5 HELSDFGLESTAGE-IPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKS : :. :::.. :. . .: ..:.: :.. . . .. : . ..:..: :: : CCDS42 HVLQYFGLKAEAAPTLRLVNLETTK--KYAPVDGGPVTAASITAFCHAVLNGQVKPYLLS 330 340 350 360 370 370 380 390 400 410 420 pF1KB5 EPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD . :: . : :::..:..::.... .:.:.:...:::::: :::.. : .. :.:: . CCDS42 QEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDH 380 390 400 410 420 430 430 440 450 460 470 480 pF1KB5 PNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATN .:.::..:::::.. . . :.::::. . ::. . .:.. :.: : ..:. : CCDS42 EDIIIAELDATANELDA-FAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLD----N 440 450 460 470 480 490 490 500 pF1KB5 PPVIQEEKPKKKKKAQEDL :. :.: .. : CCDS42 GGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL 500 510 520 >>CCDS11787.1 P4HB gene_id:5034|Hs108|chr17 (508 aa) initn: 675 init1: 280 opt: 643 Z-score: 771.1 bits: 152.2 E(32554): 1.2e-36 Smith-Waterman score: 853; 34.7% identity (63.5% similar) in 498 aa overlap (3-481:2-471) 10 20 30 40 50 60 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC ::: : .:: :. : . :: : .:: .. . .::::.::::::: CCDS11 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA---AHKYLLVEFYAPWCGHC 10 20 30 40 50 70 80 90 100 110 pF1KB5 KRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--Y : ::::: :: .::. . ::::: : ... ..::: ::::.:.::.:. :. : CCDS11 KALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 DGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAA . : :: ::. :::..:::.. : .... .......::: : :.. ..::.:: CCDS11 TAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 SNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKF . :. :. :. .. ..:. . .:..::. ::.. . : ..:. .. : CCDS11 EAI-DDIPFGITSNSDVFSKYQLDKDGVVLFK------KFDEGRNNF-EGEVTKENLLDF 180 190 200 210 220 240 250 260 270 280 pF1KB5 IQENIFGICPHMTEDNKDLIQGKD-----LLIAYYDV-DYEKNAKGSNY------WRNRV :..: . . ..::.. : : . ::. .: :: ..: ::. ..... CCDS11 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDY--DGKLSNFKTAAESFKGKI 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB5 MMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFS ... :.:. : : . : :::.. : :.: . : . : .. : CCDS11 LFI---FIDSDHTDNQRI---------LEFFGLKKE--ECPAVRLITLEEEMTKYKPESE 290 300 310 320 330 350 360 370 380 390 400 pF1KB5 R-DGKALERFLQDYFDGNLKRYLKSEPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEF . .. . .: . ...:..: .: :. .::. : ::::.:..::.... .:.:.:..:: CCDS11 ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF 340 350 360 370 380 390 410 420 430 440 450 460 pF1KB5 YAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKK :::::::::.: : . .::: . ::::::::.:::.: . .:..:::. : ::. CCDS11 YAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASAD 400 410 420 430 440 450 470 480 490 500 pF1KB5 LNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL . :.: : :. : ..:. CCDS11 RTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL 460 470 480 490 500 >>CCDS10584.1 PDILT gene_id:204474|Hs108|chr16 (584 aa) initn: 242 init1: 214 opt: 372 Z-score: 444.9 bits: 92.1 E(32554): 1.8e-18 Smith-Waterman score: 438; 23.7% identity (61.4% similar) in 443 aa overlap (47-481:62-490) 20 30 40 50 60 70 pF1KB5 AAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL-- ...: : : . . :: : :. . CCDS10 HITKPVHILEERSLLVLTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLAEELGKAVEIMGK 40 50 60 70 80 90 80 90 100 110 120 130 pF1KB5 -KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGE--EAGAYDGPRTADGIVSHLKKQ :. . ..::: : . . ...:.. : ::.: .:. : . : . ..: :..: CCDS10 GKNGIGFGKVDITIEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQ 100 110 120 130 140 150 140 150 160 170 180 190 pF1KB5 AGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVES . . . . :. .:. .. :::::.: :. : . ... . :. .. . CCDS10 ISQKAFLFNSSEQVAEFVISRPLVIVGFFQDLEEEVAELFYDVIKDF-PELTFGVITIGN 160 170 180 190 200 210 200 210 220 230 240 250 pF1KB5 LVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDN ..... . .....:. ....:. .: . . .:. .... :.... . ... .: CCDS10 VIGRFHVTLDSVLVFKKGKIVNR--QKLINDSTNKQ---ELNRVIKQHLTDFVIEYNTEN 220 230 240 250 260 260 270 280 290 300 310 pF1KB5 KDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA-VASRKTFSHE ::::. . ..... . :.... . .. ...:.: . :. : : . . . . CCDS10 KDLIS-ELHIMSHMLLFVSKSSESYGIIIQHYKLASKEFQN---KILFILVDADEPRNGR 270 280 290 300 310 320 320 330 340 350 360 pF1KB5 LSDFGLESTAGEIPVVAIRTAKGE-KFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEP . . .. : .:: : : . ... .. : . . ..:..: ..... : .. .:: CCDS10 VFKY-FRVTEVDIPSVQILNLSSDARYKMPSD-DITYESLKKFGRSFLSKNATKHQSSEE 330 340 350 360 370 370 380 390 400 410 420 pF1KB5 IPESND-GPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPN ::. : : :: .:..::. .: ...:::.. ::::: .:: : : .:::.: .. . CCDS10 IPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHST 380 390 400 410 420 430 430 440 450 460 470 480 pF1KB5 IVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPP :.:::.:.::::. : : .: . . :.... . :.: . :. : ..:. CCDS10 IIIAKIDVTANDIQLMYLDR-YPFFRLFPSGSQ-QAVLYKGEHTLKGFSDFLESHIKTKI 440 450 460 470 480 490 490 500 pF1KB5 VIQEEKPKKKKKAQEDL CCDS10 EDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKT 500 510 520 530 540 550 >>CCDS62853.1 PDIA6 gene_id:10130|Hs108|chr2 (445 aa) initn: 423 init1: 249 opt: 312 Z-score: 374.7 bits: 78.7 E(32554): 1.5e-14 Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:162-333) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE .. .::.:::::.:.. . : : . .:: CCDS62 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE 140 150 160 170 180 60 70 80 90 100 pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR :.:::::::: : ::. :::...: : : :: :: :.: ..::. :.::.:::. CCDS62 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ 190 200 210 220 230 240 110 120 130 140 150 160 pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD- :: ::: :: . :::. .. .: : . . .:. :. ... .:. . CCDS62 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH 250 260 270 280 290 300 170 180 190 200 210 pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT :. . ... .:.. .: :.:. CCDS62 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA 310 320 330 340 350 360 >-- initn: 278 init1: 249 opt: 312 Z-score: 374.7 bits: 78.7 E(32554): 1.5e-14 Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:7-129) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVA---LLLAAARLAAASD-VLELTDDNFESRISDTGSAGLMLVEFFAP .: ::.. ..::. : ..:: :.::: .::. .. .. : : ::::.:: CCDS62 MYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAP 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 WCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA- :::::.::.::.. ::: :: .: .. :: . . ..:::.:.::.::: .... CCDS62 WCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPED 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKA :.: ::...:: CCDS62 YQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKN 120 130 140 150 160 170 >>CCDS62855.1 PDIA6 gene_id:10130|Hs108|chr2 (488 aa) initn: 423 init1: 249 opt: 312 Z-score: 374.1 bits: 78.7 E(32554): 1.6e-14 Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:205-376) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE .. .::.:::::.:.. . : : . .:: CCDS62 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE 180 190 200 210 220 230 60 70 80 90 100 pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR :.:::::::: : ::. :::...: : : :: :: :.: ..::. :.::.:::. CCDS62 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ 240 250 260 270 280 290 110 120 130 140 150 160 pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD- :: ::: :: . :::. .. .: : . . .:. :. ... .:. . CCDS62 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH 300 310 320 330 340 350 170 180 190 200 210 pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT :. . ... .:.. .: :.:. CCDS62 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA 360 370 380 390 400 410 >-- initn: 254 init1: 249 opt: 312 Z-score: 374.1 bits: 78.7 E(32554): 1.6e-14 Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:50-172) 10 20 30 pF1KB5 MRLRRLALFPGVA---LLLAAARLAAASD-VLELT .: ::.. ..::. : ..:: :.::: CCDS62 ILARRSDRGSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELT 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 DDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNT .::. .. .. : : ::::.:::::::.::.::.. ::: :: .: .. :: . . CCDS62 PSNFNREVIQSDS--LWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSL 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 CNKYGVSGYPTLKIFRDGEEAGA-YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFIS ..:::.:.::.::: .... :.: ::...:: CCDS62 GGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSG 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB5 DKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSH CCDS62 KQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKE 200 210 220 230 240 250 >>CCDS62854.1 PDIA6 gene_id:10130|Hs108|chr2 (492 aa) initn: 423 init1: 249 opt: 312 Z-score: 374.1 bits: 78.7 E(32554): 1.6e-14 Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:209-380) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE .. .::.:::::.:.. . : : . .:: CCDS62 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE 180 190 200 210 220 230 60 70 80 90 100 pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR :.:::::::: : ::. :::...: : : :: :: :.: ..::. :.::.:::. CCDS62 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ 240 250 260 270 280 290 110 120 130 140 150 160 pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD- :: ::: :: . :::. .. .: : . . .:. :. ... .:. . CCDS62 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH 300 310 320 330 340 350 170 180 190 200 210 pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT :. . ... .:.. .: :.:. CCDS62 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA 360 370 380 390 400 410 >-- initn: 249 init1: 249 opt: 312 Z-score: 374.1 bits: 78.7 E(32554): 1.6e-14 Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:54-176) 10 20 30 pF1KB5 MRLRRLALFPGVA---LLLAAARLAAASD-VLELT .: ::.. ..::. : ..:: :.::: CCDS62 NISSDFQPCSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELT 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB5 DDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNT .::. .. .. : : ::::.:::::::.::.::.. ::: :: .: .. :: . . CCDS62 PSNFNREVIQSDS--LWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSL 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB5 CNKYGVSGYPTLKIFRDGEEAGA-YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFIS ..:::.:.::.::: .... :.: ::...:: CCDS62 GGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSG 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB5 DKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSH CCDS62 KQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKE 210 220 230 240 250 260 >>CCDS1675.1 PDIA6 gene_id:10130|Hs108|chr2 (440 aa) initn: 423 init1: 249 opt: 310 Z-score: 372.4 bits: 78.2 E(32554): 2e-14 Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:157-328) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE .. .::.:::::.:.. . : : . .:: CCDS16 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE 130 140 150 160 170 180 60 70 80 90 100 pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR :.:::::::: : ::. :::...: : : :: :: :.: ..::. :.::.:::. CCDS16 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ 190 200 210 220 230 240 110 120 130 140 150 160 pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD- :: ::: :: . :::. .. .: : . . .:. :. ... .:. . CCDS16 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH 250 260 270 280 290 300 170 180 190 200 210 pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT :. . ... .:.. .: :.:. CCDS16 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA 310 320 330 340 350 360 >-- initn: 258 init1: 249 opt: 310 Z-score: 372.4 bits: 78.2 E(32554): 2e-14 Smith-Waterman score: 310; 41.3% identity (72.2% similar) in 126 aa overlap (1-125:1-124) 10 20 30 40 50 60 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC : : :.: . .: . . ....::.::: .::. .. .. : : ::::.::::::: CCDS16 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAPWCGHC 10 20 30 40 50 70 80 90 100 110 pF1KB5 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGPR .::.::.. ::: :: .: .. :: . . ..:::.:.::.::: .... :.: : CCDS16 QRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 TADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLR :...:: CCDS16 TGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSE 120 130 140 150 160 170 >>CCDS62852.1 PDIA6 gene_id:10130|Hs108|chr2 (437 aa) initn: 423 init1: 249 opt: 308 Z-score: 370.0 bits: 77.8 E(32554): 2.7e-14 Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:154-325) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE .. .::.:::::.:.. . : : . .:: CCDS62 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE 130 140 150 160 170 180 60 70 80 90 100 pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR :.:::::::: : ::. :::...: : : :: :: :.: ..::. :.::.:::. CCDS62 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ 190 200 210 220 230 240 110 120 130 140 150 160 pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD- :: ::: :: . :::. .. .: : . . .:. :. ... .:. . CCDS62 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH 250 260 270 280 290 300 170 180 190 200 210 pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT :. . ... .:.. .: :.:. CCDS62 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA 310 320 330 340 350 360 >-- initn: 278 init1: 249 opt: 308 Z-score: 370.0 bits: 77.8 E(32554): 2.7e-14 Smith-Waterman score: 308; 44.7% identity (75.4% similar) in 114 aa overlap (14-125:10-121) 10 20 30 40 50 pF1KB5 MRLRRLALFPGVALLLAAARLAAASD-VLELTDDNFESRISDTGSAGLMLVEFFAPWCGH ..::. : ..:: :.::: .::. .. .. : : ::::.:::::: CCDS62 MILGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAPWCGH 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 CKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGP :.::.::.. ::: :: .: .. :: . . ..:::.:.::.::: .... :.: CCDS62 CQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 RTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNL ::...:: CCDS62 RTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDS 120 130 140 150 160 170 505 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:43:16 2016 done: Fri Nov 4 22:43:17 2016 Total Scan time: 3.180 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]