Result of FASTA (ccds) for pF1KB5019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5019, 505 aa
  1>>>pF1KB5019 505 - 505 aa - 505 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4839+/-0.000927; mu= 16.9636+/- 0.056
 mean_var=69.4142+/-13.322, 0's: 0 Z-trim(105.1): 45  B-trim: 3 in 1/49
 Lambda= 0.153940
 statistics sampled from 8182 (8221) to 8182 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.253), width:  16
 Scan time:  3.180

The best scores are:                                      opt bits E(32554)
CCDS10101.1 PDIA3 gene_id:2923|Hs108|chr15         ( 505) 3347 752.8 2.1e-217
CCDS5893.1 PDIA4 gene_id:9601|Hs108|chr7           ( 645) 1194 274.7 2.2e-73
CCDS42089.1 PDIA2 gene_id:64714|Hs108|chr16        ( 525)  722 169.8 6.7e-42
CCDS11787.1 P4HB gene_id:5034|Hs108|chr17          ( 508)  643 152.2 1.2e-36
CCDS10584.1 PDILT gene_id:204474|Hs108|chr16       ( 584)  372 92.1 1.8e-18
CCDS62853.1 PDIA6 gene_id:10130|Hs108|chr2         ( 445)  312 78.7 1.5e-14
CCDS62855.1 PDIA6 gene_id:10130|Hs108|chr2         ( 488)  312 78.7 1.6e-14
CCDS62854.1 PDIA6 gene_id:10130|Hs108|chr2         ( 492)  312 78.7 1.6e-14
CCDS1675.1 PDIA6 gene_id:10130|Hs108|chr2          ( 440)  310 78.2   2e-14
CCDS62852.1 PDIA6 gene_id:10130|Hs108|chr2         ( 437)  308 77.8 2.7e-14
CCDS32840.1 TMX3 gene_id:54495|Hs108|chr18         ( 454)  299 75.8 1.1e-13
CCDS4505.1 TXNDC5 gene_id:81567|Hs108|chr6         ( 432)  281 71.8 1.7e-12
CCDS3020.1 PDIA5 gene_id:10954|Hs108|chr3          ( 519)  257 66.5 8.1e-11


>>CCDS10101.1 PDIA3 gene_id:2923|Hs108|chr15              (505 aa)
 initn: 3347 init1: 3347 opt: 3347  Z-score: 4016.7  bits: 752.8 E(32554): 2.1e-217
Smith-Waterman score: 3347; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505)

               10        20        30        40        50        60
pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 NYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 NYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 VASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 LKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYL
              430       440       450       460       470       480

              490       500     
pF1KB5 QREATNPPVIQEEKPKKKKKAQEDL
       :::::::::::::::::::::::::
CCDS10 QREATNPPVIQEEKPKKKKKAQEDL
              490       500     

>>CCDS5893.1 PDIA4 gene_id:9601|Hs108|chr7                (645 aa)
 initn: 824 init1: 400 opt: 1194  Z-score: 1430.9  bits: 274.7 E(32554): 2.2e-73
Smith-Waterman score: 1194; 42.1% identity (71.8% similar) in 478 aa overlap (28-493:180-644)

                  10        20        30        40        50       
pF1KB5    MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWC
                                     : :: .::.  ..:   : ..::::.::::
CCDS58 DYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVND---ADIILVEFYAPWC
     150       160       170       180       190          200      

        60        70           80        90       100       110    
pF1KB5 GHCKRLAPEYEAAATRLKG---IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA
       ::::.:::::: :: .:.     .:::::: ::.:.  ... ::::::::::: :.    
CCDS58 GHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYD-
        210       220       230       240       250       260      

          120       130       140       150        160       170   
pF1KB5 YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISD-KDASIVGFFDDSFSEAHSEFLK
       :.:::   :::... .:.:: :  . : .. ..:..:  :. :.: :    . :....  
CCDS58 YNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQD
         270       280       290       300       310       320     

           180       190       200        210       220       230  
pF1KB5 AASNLRDNYRFAHTNVESLVNEYDDNGEG-IILFRPSHLTNKFEDKTVAYTEQKMTSGK-
       ::.:::..:.: ::   . . ..   ..: .....: .. .:.: ..  .  :  :. . 
CCDS58 AANNLREDYKFHHT-FSTEIAKFLKVSQGQLVVMQPEKFQSKYEPRSHMMDVQGSTQDSA
         330        340       350       360       370       380    

             240         250       260       270        280        
pF1KB5 IKKFIQENIFGICPH--MTEDNKDLIQGKDLLIAYYDVDYEKNAKG-SNYWRNRVMMVAK
       :: :. .  . .  :  ...: :   . . :...::.::.  . .. ...::..:. :::
CCDS58 IKDFVLKYALPLVGHRKVSNDAKRYTR-RPLVVVYYSVDFSFDYRAATQFWRSKVLEVAK
          390       400       410        420       430       440   

      290       300       310       320       330        340       
pF1KB5 KFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQ-EEFSRDGK
        :     . .::.:... .. :..:.:: : .::   .::   .:.::.:. :::. :  
CCDS58 DF----PEYTFAIADEEDYAGEVKDLGL-SESGEDVNAAILDESGKKFAMEPEEFDSD--
               450       460        470       480       490        

       350       360       370       380       390       400       
pF1KB5 ALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCG
       .:..:.  .  :.::  .::.:.:..: :::::::...:: :: . .:::::::::::::
CCDS58 TLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCG
        500       510       520       530       540       550      

       410       420       430       440        450       460      
pF1KB5 HCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSP-YEVRGFPTIYFSPANKKLNPKK
       :::.::: :. :..: . . ..::::::::::::::  :.:.:::::::.:.. : :: :
CCDS58 HCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNPVK
        560       570       580       590       600       610      

        470        480       490       500     
pF1KB5 YEGG-RELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL
       .::: :.:  . ......::.    .::            
CCDS58 FEGGDRDLEHLSKFIEEHATKLSRTKEEL           
        620       630       640                

>--
 initn: 303 init1: 152 opt: 315  Z-score: 375.9  bits: 79.4 E(32554): 1.3e-14
Smith-Waterman score: 315; 42.6% identity (71.3% similar) in 115 aa overlap (27-138:64-174)

                   10        20        30        40        50      
pF1KB5     MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPW
                                     :: :.: ::.. ..:  .   .:.::.:::
CCDS58 RENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDT---VLLEFYAPW
            40        50        60        70        80           90

         60        70           80        90       100       110   
pF1KB5 CGHCKRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG
       :::::..:::::  :. ::     .:.::.: :. .   ... ::::::.::.. :. : 
CCDS58 CGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQ-AV
              100       110       120       130       140          

           120       130       140       150       160       170   
pF1KB5 AYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLK
        :.: :: . ::..... . :  .:                                   
CCDS58 DYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHC
     150       160       170       180       190       200         

>>CCDS42089.1 PDIA2 gene_id:64714|Hs108|chr16             (525 aa)
 initn: 643 init1: 244 opt: 722  Z-score: 865.7  bits: 169.8 E(32554): 6.7e-42
Smith-Waterman score: 722; 30.1% identity (61.7% similar) in 465 aa overlap (48-501:62-508)

        20        30        40        50        60        70       
pF1KB5 AARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKG-
                                     .::::.:::::::. :::::  ::. : . 
CCDS42 EPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAE
              40        50        60        70        80        90 

           80        90       100       110         120       130  
pF1KB5 --IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQA
         .: :::::  :. .  ...::. :::::.::.:...    : ::: :.::.  :....
CCDS42 SMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRV
             100       110       120       130       140       150 

            140       150       160       170       180       190  
pF1KB5 GPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESL
       ::... :. :   . .:. .:  ..:::.:  .:  . ::  :..  : . :. :.   :
CCDS42 GPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALD-MTFGLTDRPRL
             160       170       180       190        200       210

            200       210       220          230        240        
pF1KB5 VNEYDDNGEGIILFRPSHLTNKFEDKTVAYT---EQKMTSGKIKKF-IQENIFGICPHMT
        ...  . . ..::.      ::..  . .    :  .  : ...: . ...  .    .
CCDS42 FQQFGLTKDTVVLFK------KFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNS
              220             230       240       250       260    

      250       260       270       280       290       300        
pF1KB5 EDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFS
       . .  .. ..  .. .  .  ...  .          .: .:   :. :  .:       
CCDS42 QTSAKIFAAR--ILNHLLLFVNQTLAAHRELLAGFGEAAPRF--RGQVLFVVVDVAADNE
          270         280       290       300         310       320

      310       320        330       340       350       360       
pF1KB5 HELSDFGLESTAGE-IPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKS
       : :. :::.. :.  . .: ..:.:  :..  .     . ..  : .  ..:..: :: :
CCDS42 HVLQYFGLKAEAAPTLRLVNLETTK--KYAPVDGGPVTAASITAFCHAVLNGQVKPYLLS
              330       340         350       360       370        

       370        380       390       400       410       420      
pF1KB5 EPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD
       . :: . :  :::..:..::.... .:.:.:...:::::: :::.. : .. :.:: .  
CCDS42 QEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDH
      380       390       400       410       420       430        

        430       440       450       460       470       480      
pF1KB5 PNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATN
        .:.::..:::::.. . . :.::::. . ::.   .  .:.. :.:  : ..:.    :
CCDS42 EDIIIAELDATANELDA-FAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLD----N
      440       450        460       470       480       490       

        490       500                  
pF1KB5 PPVIQEEKPKKKKKAQEDL             
         :.  :.: ..  :                 
CCDS42 GGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL
           500       510       520     

>>CCDS11787.1 P4HB gene_id:5034|Hs108|chr17               (508 aa)
 initn: 675 init1: 280 opt: 643  Z-score: 771.1  bits: 152.2 E(32554): 1.2e-36
Smith-Waterman score: 853; 34.7% identity (63.5% similar) in 498 aa overlap (3-481:2-471)

               10        20        30        40        50        60
pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
         :::  :  .:: :. :      . :: :  .::   ..   .   .::::.:::::::
CCDS11  MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA---AHKYLLVEFYAPWCGHC
                10        20        30           40        50      

               70           80        90       100       110       
pF1KB5 KRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--Y
       : :::::  :: .::.    . ::::: : ...  ..::: ::::.:.::.:. :.   :
CCDS11 KALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEY
         60        70        80        90       100       110      

         120       130       140       150       160       170     
pF1KB5 DGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAA
        . : :: ::. :::..:::.. :      .... .......::: :  :.. ..::.::
CCDS11 TAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAA
        120       130       140       150       160       170      

         180       190       200       210       220       230     
pF1KB5 SNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKF
         . :.  :. :.  .. ..:. . .:..::.      ::..    . : ..:. ..  :
CCDS11 EAI-DDIPFGITSNSDVFSKYQLDKDGVVLFK------KFDEGRNNF-EGEVTKENLLDF
         180       190       200             210        220        

         240       250            260        270             280   
pF1KB5 IQENIFGICPHMTEDNKDLIQGKD-----LLIAYYDV-DYEKNAKGSNY------WRNRV
       :..: . .  ..::..   : : .     ::.   .: ::  ..: ::.      .....
CCDS11 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDY--DGKLSNFKTAAESFKGKI
      230       240       250       260         270       280      

           290       300       310       320       330       340   
pF1KB5 MMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFS
       ...   :.:. :  :  .         :  :::..   : :.: . : . :   .. :  
CCDS11 LFI---FIDSDHTDNQRI---------LEFFGLKKE--ECPAVRLITLEEEMTKYKPESE
           290       300                310         320       330  

            350       360       370        380       390       400 
pF1KB5 R-DGKALERFLQDYFDGNLKRYLKSEPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEF
       .  .. . .: . ...:..: .: :. .::. :  ::::.:..::.... .:.:.:..::
CCDS11 ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF
            340       350       360       370       380       390  

             410       420       430       440       450       460 
pF1KB5 YAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKK
       :::::::::.: : . .:::  .   ::::::::.:::.: .  .:..:::. : ::.  
CCDS11 YAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASAD
            400       410       420       430        440       450 

             470       480       490       500                  
pF1KB5 LNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL             
        .   :.: : :. : ..:.                                     
CCDS11 RTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
             460       470       480       490       500        

>>CCDS10584.1 PDILT gene_id:204474|Hs108|chr16            (584 aa)
 initn: 242 init1: 214 opt: 372  Z-score: 444.9  bits: 92.1 E(32554): 1.8e-18
Smith-Waterman score: 438; 23.7% identity (61.4% similar) in 443 aa overlap (47-481:62-490)

         20        30        40        50        60        70      
pF1KB5 AAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL--
                                     ...: :  :   . . :: :   :.  .  
CCDS10 HITKPVHILEERSLLVLTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLAEELGKAVEIMGK
              40        50        60        70        80        90 

            80        90       100       110         120       130 
pF1KB5 -KGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGE--EAGAYDGPRTADGIVSHLKKQ
        :. . ..::: : . .  ...:..  : ::.: .:.  :  .  :   . ..:  :..:
CCDS10 GKNGIGFGKVDITIEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQ
             100       110       120       130       140       150 

             140       150       160       170       180       190 
pF1KB5 AGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVES
        .  .  . . :.  .:. ..   :::::.:   :.   :  . ...  .  :.  .. .
CCDS10 ISQKAFLFNSSEQVAEFVISRPLVIVGFFQDLEEEVAELFYDVIKDF-PELTFGVITIGN
             160       170       180       190        200       210

             200       210       220       230       240       250 
pF1KB5 LVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDN
       .....  . .....:. ....:.  .: .  . .:.   .... :....  .  ... .:
CCDS10 VIGRFHVTLDSVLVFKKGKIVNR--QKLINDSTNKQ---ELNRVIKQHLTDFVIEYNTEN
              220       230         240          250       260     

             260       270       280       290       300        310
pF1KB5 KDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA-VASRKTFSHE
       ::::. .  ..... .   :.... .   ..  ...:.: .   :. :  : . .  . .
CCDS10 KDLIS-ELHIMSHMLLFVSKSSESYGIIIQHYKLASKEFQN---KILFILVDADEPRNGR
         270        280       290       300          310       320 

              320       330        340       350       360         
pF1KB5 LSDFGLESTAGEIPVVAIRTAKGE-KFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEP
       .  . .. :  .:: : : . ... .. :  . .   ..:..: ..... :  .. .:: 
CCDS10 VFKY-FRVTEVDIPSVQILNLSSDARYKMPSD-DITYESLKKFGRSFLSKNATKHQSSEE
              330       340       350        360       370         

     370        380       390       400       410       420        
pF1KB5 IPESND-GPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPN
       ::.  : : :: .:..::. .: ...:::.. :::::  .:: : :  .:::.: ..  .
CCDS10 IPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHST
     380       390       400       410       420       430         

      430       440       450       460       470       480        
pF1KB5 IVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPP
       :.:::.:.::::.   :  : .: . . :.... .   :.: . :. : ..:.       
CCDS10 IIIAKIDVTANDIQLMYLDR-YPFFRLFPSGSQ-QAVLYKGEHTLKGFSDFLESHIKTKI
     440       450        460       470        480       490       

      490       500                                                
pF1KB5 VIQEEKPKKKKKAQEDL                                           
                                                                   
CCDS10 EDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKT
       500       510       520       530       540       550       

>>CCDS62853.1 PDIA6 gene_id:10130|Hs108|chr2              (445 aa)
 initn: 423 init1: 249 opt: 312  Z-score: 374.7  bits: 78.7 E(32554): 1.5e-14
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:162-333)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
CCDS62 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
             140       150       160       170       180           

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
CCDS62 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
     190       200       210       220       230       240         

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
CCDS62 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
     250       260       270       280       290       300         

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
CCDS62 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
     310       320       330       340       350       360         

>--
 initn: 278 init1: 249 opt: 312  Z-score: 374.7  bits: 78.7 E(32554): 1.5e-14
Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:7-129)

                10           20         30        40        50     
pF1KB5  MRLRRLALFPGVA---LLLAAARLAAASD-VLELTDDNFESRISDTGSAGLMLVEFFAP
             .:  ::..   ..::.  : ..:: :.::: .::. .. .. :  : ::::.::
CCDS62 MYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAP
               10        20        30        40          50        

          60        70        80        90       100       110     
pF1KB5 WCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-
       :::::.::.::.. ::: :: .: .. ::   . .  ..:::.:.::.::: ....    
CCDS62 WCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPED
       60        70        80        90       100       110        

          120       130       140       150       160       170    
pF1KB5 YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKA
       :.: ::...::                                                 
CCDS62 YQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKN
      120       130       140       150       160       170        

>>CCDS62855.1 PDIA6 gene_id:10130|Hs108|chr2              (488 aa)
 initn: 423 init1: 249 opt: 312  Z-score: 374.1  bits: 78.7 E(32554): 1.6e-14
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:205-376)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
CCDS62 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
          180       190       200       210       220         230  

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
CCDS62 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
            240       250       260       270       280       290  

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
CCDS62 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
            300       310       320       330       340       350  

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
CCDS62 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
            360       370       380       390       400       410  

>--
 initn: 254 init1: 249 opt: 312  Z-score: 374.1  bits: 78.7 E(32554): 1.6e-14
Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:50-172)

                                        10           20         30 
pF1KB5                          MRLRRLALFPGVA---LLLAAARLAAASD-VLELT
                                     .:  ::..   ..::.  : ..:: :.:::
CCDS62 ILARRSDRGSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELT
      20        30        40        50        60        70         

              40        50        60        70        80        90 
pF1KB5 DDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNT
        .::. .. .. :  : ::::.:::::::.::.::.. ::: :: .: .. ::   . . 
CCDS62 PSNFNREVIQSDS--LWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSL
      80        90         100       110       120       130       

             100       110        120       130       140       150
pF1KB5 CNKYGVSGYPTLKIFRDGEEAGA-YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFIS
        ..:::.:.::.::: ....    :.: ::...::                         
CCDS62 GGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSG
       140       150       160       170       180       190       

              160       170       180       190       200       210
pF1KB5 DKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSH
                                                                   
CCDS62 KQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKE
       200       210       220       230       240       250       

>>CCDS62854.1 PDIA6 gene_id:10130|Hs108|chr2              (492 aa)
 initn: 423 init1: 249 opt: 312  Z-score: 374.1  bits: 78.7 E(32554): 1.6e-14
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:209-380)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
CCDS62 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
      180       190       200       210       220         230      

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
CCDS62 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
        240       250       260       270       280       290      

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
CCDS62 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
        300       310       320       330       340       350      

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
CCDS62 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
        360       370       380       390       400       410      

>--
 initn: 249 init1: 249 opt: 312  Z-score: 374.1  bits: 78.7 E(32554): 1.6e-14
Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:54-176)

                                        10           20         30 
pF1KB5                          MRLRRLALFPGVA---LLLAAARLAAASD-VLELT
                                     .:  ::..   ..::.  : ..:: :.:::
CCDS62 NISSDFQPCSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELT
            30        40        50        60        70        80   

              40        50        60        70        80        90 
pF1KB5 DDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNT
        .::. .. .. :  : ::::.:::::::.::.::.. ::: :: .: .. ::   . . 
CCDS62 PSNFNREVIQSDS--LWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSL
            90         100       110       120       130       140 

             100       110        120       130       140       150
pF1KB5 CNKYGVSGYPTLKIFRDGEEAGA-YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFIS
        ..:::.:.::.::: ....    :.: ::...::                         
CCDS62 GGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSG
             150       160       170       180       190       200 

              160       170       180       190       200       210
pF1KB5 DKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSH
                                                                   
CCDS62 KQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKE
             210       220       230       240       250       260 

>>CCDS1675.1 PDIA6 gene_id:10130|Hs108|chr2               (440 aa)
 initn: 423 init1: 249 opt: 310  Z-score: 372.4  bits: 78.2 E(32554): 2e-14
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:157-328)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
CCDS16 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
        130       140       150       160       170         180    

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
CCDS16 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
          190       200       210       220       230       240    

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
CCDS16 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
          250       260       270       280       290       300    

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
CCDS16 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
          310       320       330       340       350       360    

>--
 initn: 258 init1: 249 opt: 310  Z-score: 372.4  bits: 78.2 E(32554): 2e-14
Smith-Waterman score: 310; 41.3% identity (72.2% similar) in 126 aa overlap (1-125:1-124)

               10        20        30        40        50        60
pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
       : :  :.:   . .: . .  ....::.::: .::. .. .. :  : ::::.:::::::
CCDS16 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAPWCGHC
               10        20        30        40          50        

               70        80        90       100       110          
pF1KB5 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGPR
       .::.::.. ::: :: .: .. ::   . .  ..:::.:.::.::: ....    :.: :
CCDS16 QRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGR
       60        70        80        90       100       110        

     120       130       140       150       160       170         
pF1KB5 TADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLR
       :...::                                                      
CCDS16 TGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSE
      120       130       140       150       160       170        

>>CCDS62852.1 PDIA6 gene_id:10130|Hs108|chr2              (437 aa)
 initn: 423 init1: 249 opt: 308  Z-score: 370.0  bits: 77.8 E(32554): 2.7e-14
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:154-325)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
CCDS62 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
           130       140       150       160       170         180 

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
CCDS62 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
             190       200       210       220       230       240 

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
CCDS62 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
             250       260       270       280       290       300 

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
CCDS62 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
             310       320       330       340       350       360 

>--
 initn: 278 init1: 249 opt: 308  Z-score: 370.0  bits: 77.8 E(32554): 2.7e-14
Smith-Waterman score: 308; 44.7% identity (75.4% similar) in 114 aa overlap (14-125:10-121)

               10        20         30        40        50         
pF1KB5 MRLRRLALFPGVALLLAAARLAAASD-VLELTDDNFESRISDTGSAGLMLVEFFAPWCGH
                    ..::.  : ..:: :.::: .::. .. .. :  : ::::.::::::
CCDS62     MILGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAPWCGH
                   10        20        30        40          50    

      60        70        80        90       100       110         
pF1KB5 CKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGP
       :.::.::.. ::: :: .: .. ::   . .  ..:::.:.::.::: ....    :.: 
CCDS62 CQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGG
           60        70        80        90       100       110    

      120       130       140       150       160       170        
pF1KB5 RTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNL
       ::...::                                                     
CCDS62 RTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDS
          120       130       140       150       160       170    




505 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 22:43:16 2016 done: Fri Nov  4 22:43:17 2016
 Total Scan time:  3.180 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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