FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5023, 329 aa 1>>>pF1KB5023 329 - 329 aa - 329 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6518+/-0.000452; mu= 19.9288+/- 0.028 mean_var=68.3349+/-14.130, 0's: 0 Z-trim(109.3): 70 B-trim: 0 in 0/51 Lambda= 0.155150 statistics sampled from 17411 (17481) to 17411 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.205), width: 16 Scan time: 6.550 The best scores are: opt bits E(85289) NP_001123514 (OMIM: 123691) quinone oxidoreductase ( 329) 2113 482.3 6e-136 XP_011539049 (OMIM: 123691) PREDICTED: quinone oxi ( 329) 2113 482.3 6e-136 NP_001880 (OMIM: 123691) quinone oxidoreductase is ( 329) 2113 482.3 6e-136 NP_001123515 (OMIM: 123691) quinone oxidoreductase ( 295) 1381 318.4 1.2e-86 XP_016855856 (OMIM: 123691) PREDICTED: quinone oxi ( 295) 1381 318.4 1.2e-86 XP_005270548 (OMIM: 123691) PREDICTED: quinone oxi ( 192) 1190 275.5 6.3e-74 XP_016855857 (OMIM: 123691) PREDICTED: quinone oxi ( 192) 1190 275.5 6.3e-74 NP_001128231 (OMIM: 123691) quinone oxidoreductase ( 192) 1190 275.5 6.3e-74 NP_006364 (OMIM: 604631) synaptic vesicle membrane ( 393) 525 126.9 6.8e-29 NP_004872 (OMIM: 605171) quinone oxidoreductase PI ( 332) 381 94.6 3e-19 NP_671713 (OMIM: 605171) quinone oxidoreductase PI ( 332) 381 94.6 3e-19 NP_001193731 (OMIM: 605171) quinone oxidoreductase ( 248) 313 79.3 9.4e-15 XP_006712213 (OMIM: 605171) PREDICTED: quinone oxi ( 248) 313 79.3 9.4e-15 NP_057095 (OMIM: 608205) trans-2-enoyl-CoA reducta ( 373) 275 71.0 4.6e-12 XP_011539842 (OMIM: 608205) PREDICTED: trans-2-eno ( 431) 268 69.4 1.5e-11 XP_005245942 (OMIM: 608205) PREDICTED: trans-2-eno ( 401) 262 68.1 3.6e-11 XP_011539843 (OMIM: 608205) PREDICTED: trans-2-eno ( 364) 261 67.8 4e-11 XP_011539841 (OMIM: 608205) PREDICTED: trans-2-eno ( 459) 255 66.6 1.2e-10 XP_016856902 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 251 65.5 1.6e-10 XP_005245944 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 251 65.5 1.6e-10 XP_016856903 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 251 65.5 1.6e-10 XP_016856904 (OMIM: 608205) PREDICTED: trans-2-eno ( 297) 251 65.5 1.6e-10 NP_001019903 (OMIM: 608205) trans-2-enoyl-CoA redu ( 297) 251 65.5 1.6e-10 XP_016856905 (OMIM: 608205) PREDICTED: trans-2-eno ( 260) 250 65.2 1.7e-10 XP_011539856 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_016856900 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_016856901 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_011539847 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_011539848 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_011539855 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_011539849 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_011539845 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_011539852 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 XP_011539851 (OMIM: 608205) PREDICTED: trans-2-eno ( 355) 244 64.0 5.4e-10 NP_004095 (OMIM: 600212) fatty acid synthase [Homo (2511) 251 66.3 7.5e-10 XP_011521840 (OMIM: 600212) PREDICTED: fatty acid (2511) 251 66.3 7.5e-10 XP_011516696 (OMIM: 601274) PREDICTED: prostagland ( 254) 238 62.5 1.1e-09 XP_016869974 (OMIM: 601274) PREDICTED: prostagland ( 254) 238 62.5 1.1e-09 NP_001139581 (OMIM: 601274) prostaglandin reductas ( 301) 238 62.6 1.2e-09 NP_036344 (OMIM: 601274) prostaglandin reductase 1 ( 329) 238 62.6 1.3e-09 NP_001139580 (OMIM: 601274) prostaglandin reductas ( 329) 238 62.6 1.3e-09 NP_665857 (OMIM: 603920) quinone oxidoreductase-li ( 349) 236 62.2 1.9e-09 XP_016866865 (OMIM: 610502,616732) PREDICTED: reti ( 288) 211 56.5 7.8e-08 NP_001305675 (OMIM: 610502,616732) reticulon-4-int ( 296) 211 56.5 8e-08 XP_011534494 (OMIM: 610502,616732) PREDICTED: reti ( 316) 211 56.6 8.3e-08 XP_005264707 (OMIM: 605171) PREDICTED: quinone oxi ( 243) 203 54.7 2.4e-07 XP_011516697 (OMIM: 601274) PREDICTED: prostagland ( 206) 197 53.3 5.4e-07 NP_000658 (OMIM: 103700) alcohol dehydrogenase 1A ( 375) 170 47.5 5.5e-05 NP_000661 (OMIM: 103740) alcohol dehydrogenase 4 i ( 380) 151 43.2 0.0011 NP_001293100 (OMIM: 103740) alcohol dehydrogenase ( 399) 151 43.2 0.0011 >>NP_001123514 (OMIM: 123691) quinone oxidoreductase iso (329 aa) initn: 2113 init1: 2113 opt: 2113 Z-score: 2561.7 bits: 482.3 E(85289): 6e-136 Smith-Waterman score: 2113; 99.7% identity (100.0% similar) in 329 aa overlap (1-329:1-329) 10 20 30 40 50 60 pF1KB5 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKVLGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_001 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 250 260 270 280 290 300 310 320 pF1KB5 SQYPLEKVAEAHENIIHGSGATGKMILLL ::::::::::::::::::::::::::::: NP_001 SQYPLEKVAEAHENIIHGSGATGKMILLL 310 320 >>XP_011539049 (OMIM: 123691) PREDICTED: quinone oxidore (329 aa) initn: 2113 init1: 2113 opt: 2113 Z-score: 2561.7 bits: 482.3 E(85289): 6e-136 Smith-Waterman score: 2113; 99.7% identity (100.0% similar) in 329 aa overlap (1-329:1-329) 10 20 30 40 50 60 pF1KB5 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKVLGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: XP_011 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 250 260 270 280 290 300 310 320 pF1KB5 SQYPLEKVAEAHENIIHGSGATGKMILLL ::::::::::::::::::::::::::::: XP_011 SQYPLEKVAEAHENIIHGSGATGKMILLL 310 320 >>NP_001880 (OMIM: 123691) quinone oxidoreductase isofor (329 aa) initn: 2113 init1: 2113 opt: 2113 Z-score: 2561.7 bits: 482.3 E(85289): 6e-136 Smith-Waterman score: 2113; 99.7% identity (100.0% similar) in 329 aa overlap (1-329:1-329) 10 20 30 40 50 60 pF1KB5 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKVLGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_001 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 250 260 270 280 290 300 310 320 pF1KB5 SQYPLEKVAEAHENIIHGSGATGKMILLL ::::::::::::::::::::::::::::: NP_001 SQYPLEKVAEAHENIIHGSGATGKMILLL 310 320 >>NP_001123515 (OMIM: 123691) quinone oxidoreductase iso (295 aa) initn: 1367 init1: 1367 opt: 1381 Z-score: 1676.8 bits: 318.4 E(85289): 1.2e-86 Smith-Waterman score: 1826; 89.4% identity (89.7% similar) in 329 aa overlap (1-329:1-295) 10 20 30 40 50 60 pF1KB5 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKVLGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_001 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG :::::::::::::::::::::::::::::: NP_001 GTEEGQKIVLQNGAHEVFNHREVNYIDKIK------------------------------ 190 200 210 250 260 270 280 290 300 pF1KB5 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----VVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 220 230 240 250 260 310 320 pF1KB5 SQYPLEKVAEAHENIIHGSGATGKMILLL ::::::::::::::::::::::::::::: NP_001 SQYPLEKVAEAHENIIHGSGATGKMILLL 270 280 290 >>XP_016855856 (OMIM: 123691) PREDICTED: quinone oxidore (295 aa) initn: 1367 init1: 1367 opt: 1381 Z-score: 1676.8 bits: 318.4 E(85289): 1.2e-86 Smith-Waterman score: 1826; 89.4% identity (89.7% similar) in 329 aa overlap (1-329:1-295) 10 20 30 40 50 60 pF1KB5 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKVLGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: XP_016 LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG :::::::::::::::::::::::::::::: XP_016 GTEEGQKIVLQNGAHEVFNHREVNYIDKIK------------------------------ 190 200 210 250 260 270 280 290 300 pF1KB5 GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ----VVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG 220 230 240 250 260 310 320 pF1KB5 SQYPLEKVAEAHENIIHGSGATGKMILLL ::::::::::::::::::::::::::::: XP_016 SQYPLEKVAEAHENIIHGSGATGKMILLL 270 280 290 >>XP_005270548 (OMIM: 123691) PREDICTED: quinone oxidore (192 aa) initn: 1190 init1: 1190 opt: 1190 Z-score: 1448.2 bits: 275.5 E(85289): 6.3e-74 Smith-Waterman score: 1190; 98.4% identity (99.5% similar) in 190 aa overlap (140-329:3-192) 110 120 130 140 150 160 pF1KB5 ADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIA :. ::::::::::::::::::::::::::: XP_005 MHLLSSACVKAGESVLVHGASGGVGLAACQIA 10 20 30 170 180 190 200 210 220 pF1KB5 RAYGLKVLGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVN ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVN 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB5 LSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAG 100 110 120 130 140 150 290 300 310 320 pF1KB5 MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL :::::::::::::::::::::::::::::::::::::::: XP_005 MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL 160 170 180 190 >>XP_016855857 (OMIM: 123691) PREDICTED: quinone oxidore (192 aa) initn: 1190 init1: 1190 opt: 1190 Z-score: 1448.2 bits: 275.5 E(85289): 6.3e-74 Smith-Waterman score: 1190; 98.4% identity (99.5% similar) in 190 aa overlap (140-329:3-192) 110 120 130 140 150 160 pF1KB5 ADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIA :. ::::::::::::::::::::::::::: XP_016 MHLLSSACVKAGESVLVHGASGGVGLAACQIA 10 20 30 170 180 190 200 210 220 pF1KB5 RAYGLKVLGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVN ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVN 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB5 LSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAG 100 110 120 130 140 150 290 300 310 320 pF1KB5 MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL :::::::::::::::::::::::::::::::::::::::: XP_016 MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL 160 170 180 190 >>NP_001128231 (OMIM: 123691) quinone oxidoreductase iso (192 aa) initn: 1190 init1: 1190 opt: 1190 Z-score: 1448.2 bits: 275.5 E(85289): 6.3e-74 Smith-Waterman score: 1190; 98.4% identity (99.5% similar) in 190 aa overlap (140-329:3-192) 110 120 130 140 150 160 pF1KB5 ADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIA :. ::::::::::::::::::::::::::: NP_001 MHLLSSACVKAGESVLVHGASGGVGLAACQIA 10 20 30 170 180 190 200 210 220 pF1KB5 RAYGLKVLGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVN ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVN 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB5 LSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAG 100 110 120 130 140 150 290 300 310 320 pF1KB5 MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL :::::::::::::::::::::::::::::::::::::::: NP_001 MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL 160 170 180 190 >>NP_006364 (OMIM: 604631) synaptic vesicle membrane pro (393 aa) initn: 444 init1: 207 opt: 525 Z-score: 639.7 bits: 126.9 E(85289): 6.8e-29 Smith-Waterman score: 552; 32.1% identity (65.6% similar) in 349 aa overlap (2-328:42-386) 10 20 30 pF1KB5 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVP :.. :.: . . ::: . .::.: :.: NP_006 TGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYDKVKLQSRPAAP 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB5 -IPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASAFKKG : :. ....:::.: .. . :.: :.: : :: ::: . :::. :::...: : : NP_006 PAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAG 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB5 DRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGE :::.. . :: . : . . . .. .:: . :...::. . :.::: .:. . .. :. NP_006 DRVMVLNR-SGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGH 140 150 160 170 180 190 160 170 180 190 200 pF1KB5 SVLVHGASGGVGLAACQIARAY-GLKVLGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKI ::::: :.::::.:: :. :. .. :.:::.. . .. . .::. . .... ..:.:.: NP_006 SVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASK-HEALKENGVTHPIDYHTTDYVDEI 200 210 220 230 240 210 220 230 240 250 260 pF1KB5 KKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMA------KE :: .. ::.::... :.. . .: .::. :.:.. : . . :. :: .. NP_006 KK-ISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMALARTWWNQ 250 260 270 280 290 300 270 280 290 300 pF1KB5 SSIIGVTLFSSTK--------------EEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVA :. .. :..... : . .: : : .. : .:: : : .:.:::: NP_006 FSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVA 310 320 330 340 350 360 310 320 pF1KB5 EAHENIIHGSGATGKMILLL .: ... . . .::..:. NP_006 DAMKQM-QEKKNVGKVLLVPGPEKEN 370 380 390 >>NP_004872 (OMIM: 605171) quinone oxidoreductase PIG3 i (332 aa) initn: 333 init1: 264 opt: 381 Z-score: 466.5 bits: 94.6 E(85289): 3e-19 Smith-Waterman score: 413; 28.2% identity (59.2% similar) in 333 aa overlap (8-329:1-330) 10 20 30 40 50 60 pF1KB5 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS : ::. . :::: : .. ..: : : . .::.:: : ..: .. . :.: :. NP_004 MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYD 10 20 30 40 50 70 80 90 100 110 pF1KB5 RKPLLPYTPGSDVAGVIEAVGDNASA-FKKGDRVFTSSTISGGYAEYALAADHTVYKLPE : : ...: . .: . .. .: :: .. . .:: :.:. . . .. .:: NP_004 PPPGASNILGLEASGHVAELGPGCQGHWKIGDTAM-ALLPGGGQAQYVTVPEGLLMPIPE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 KLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKVLGT : . :.::: ..::.. : . :.::. ::.:.. .::: :: :..: : : : NP_004 GLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 AGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSH ::... ... . :: ::... .. . :.. :...:.. ... :... :. NP_004 AGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLAL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 GGRVIVVGSRGTIEIN-P--RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-- :: .. : : .:: : . :..:.: : : .. :. . :. . . NP_004 DGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFST 240 250 260 270 280 290 300 310 320 pF1KB5 -----LKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL : ::. ::. .. :::. .... ::..: : NP_004 EGPQRLLPVLDRIYPVTEIQEAHK-YMEANKNIGKIVLELPQ 300 310 320 330 329 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:17:09 2016 done: Sat Nov 5 06:17:10 2016 Total Scan time: 6.550 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]