FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5024, 428 aa 1>>>pF1KB5024 428 - 428 aa - 428 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5838+/-0.0014; mu= 7.2749+/- 0.083 mean_var=152.3953+/-31.121, 0's: 0 Z-trim(103.7): 43 B-trim: 58 in 2/48 Lambda= 0.103894 statistics sampled from 7522 (7537) to 7522 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.232), width: 16 Scan time: 2.940 The best scores are: opt bits E(32554) CCDS11245.2 FLOT2 gene_id:2319|Hs108|chr17 ( 428) 2688 415.3 5.6e-116 CCDS82097.1 FLOT2 gene_id:2319|Hs108|chr17 ( 428) 2634 407.3 1.5e-113 CCDS4688.1 FLOT1 gene_id:10211|Hs108|chr6 ( 427) 1240 198.3 1.2e-50 >>CCDS11245.2 FLOT2 gene_id:2319|Hs108|chr17 (428 aa) initn: 2688 init1: 2688 opt: 2688 Z-score: 2195.7 bits: 415.3 E(32554): 5.6e-116 Smith-Waterman score: 2688; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KB5 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 EQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 EQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 AEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLI 370 380 390 400 410 420 pF1KB5 KKATGVQV :::::::: CCDS11 KKATGVQV >>CCDS82097.1 FLOT2 gene_id:2319|Hs108|chr17 (428 aa) initn: 2634 init1: 2634 opt: 2634 Z-score: 2152.0 bits: 407.3 E(32554): 1.5e-113 Smith-Waterman score: 2634; 97.7% identity (99.1% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KB5 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVE ::::::::::::::::::::::::::::::::::::::::::::.:::.::. :::..: CCDS82 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRLSLEVMTILCRCENIE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTV :.::: : :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TSEGVPLFVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 EQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDAD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 IGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 IGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 YELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 YELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 AEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 AEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 LEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLI 370 380 390 400 410 420 pF1KB5 KKATGVQV :::::::: CCDS82 KKATGVQV >>CCDS4688.1 FLOT1 gene_id:10211|Hs108|chr6 (427 aa) initn: 1406 init1: 987 opt: 1240 Z-score: 1022.8 bits: 198.3 E(32554): 1.2e-50 Smith-Waterman score: 1240; 47.6% identity (80.4% similar) in 418 aa overlap (6-417:4-419) 10 20 30 40 50 60 pF1KB5 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVE : :::::.:::: : . .: :: ... ::.. :::::. .::. . : : CCDS46 MFFTCGPNEAMVVSGFCRSPPV--MVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVY 10 20 30 40 50 70 80 90 100 110 pF1KB5 TAEGVALTVTGVAQVKIMTE-KELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLT : .:: ..:::.:::::. . ::.::.::..::::. .: ...:.::::: :.:.. .: CCDS46 TRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 VEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDA ::.::.::..:.. : .::. :. ::: ..:.:.::..: ::: ::::..:: ::.:: CCDS46 VEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 DIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQL :: :::.::::::::. :.: ........ ..: ..: .::.:.:.. ::: . :.:.: CCDS46 RIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 AYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQ ::.:: :. .:.:........::.: .:.::. ::: : .::: : ::.::::: ..... CCDS46 AYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLER 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB5 IAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMAL .::.:: . .. :.::: ..: ::::: .: : ..::::.: ::::.: : .::.. . CCDS46 LAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDM 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB5 VLEALPQIAAKIAAPLTKVDEIVVLSGDN-----SKVTSEVNRLLAELPASVHALTGVDL .:: :::.: .:..:::....:...:. . .:::.:: .:..:: ::. ::::.. CCDS46 LLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSI 360 370 380 390 400 410 420 pF1KB5 SKIPLIKKATGVQV :.. CCDS46 SQVNHKPLRTA 420 428 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:21:09 2016 done: Sat Nov 5 12:21:10 2016 Total Scan time: 2.940 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]