FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5030, 284 aa 1>>>pF1KB5030 284 - 284 aa - 284 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2666+/-0.000344; mu= 15.7710+/- 0.021 mean_var=68.7485+/-14.059, 0's: 0 Z-trim(114.3): 49 B-trim: 0 in 0/49 Lambda= 0.154683 statistics sampled from 24077 (24132) to 24077 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.283), width: 16 Scan time: 7.080 The best scores are: opt bits E(85289) NP_055166 (OMIM: 608359) sulfotransferase 4A1 [Hom ( 284) 1968 448.0 9.6e-126 XP_011528422 (OMIM: 608359) PREDICTED: sulfotransf ( 171) 1160 267.5 1.2e-71 XP_011528423 (OMIM: 608359) PREDICTED: sulfotransf ( 171) 809 189.2 4.6e-48 NP_808220 (OMIM: 600641) sulfotransferase 1A3 [Hom ( 295) 523 125.5 1.2e-28 NP_001017390 (OMIM: 615819) sulfotransferase 1A4 [ ( 295) 523 125.5 1.2e-28 NP_001045 (OMIM: 601292) sulfotransferase 1A2 [Hom ( 295) 501 120.6 3.5e-27 NP_803564 (OMIM: 601292) sulfotransferase 1A2 [Hom ( 295) 501 120.6 3.5e-27 NP_001047 (OMIM: 602385) sulfotransferase 1C2 isof ( 296) 499 120.2 4.8e-27 NP_006579 (OMIM: 608357) sulfotransferase 1C4 isof ( 302) 493 118.8 1.2e-26 XP_016879100 (OMIM: 171150) PREDICTED: sulfotransf ( 295) 489 117.9 2.3e-26 NP_803566 (OMIM: 171150) sulfotransferase 1A1 isof ( 295) 489 117.9 2.3e-26 NP_803878 (OMIM: 171150) sulfotransferase 1A1 isof ( 295) 489 117.9 2.3e-26 NP_001046 (OMIM: 171150) sulfotransferase 1A1 isof ( 295) 489 117.9 2.3e-26 XP_016879102 (OMIM: 171150) PREDICTED: sulfotransf ( 295) 489 117.9 2.3e-26 XP_016879101 (OMIM: 171150) PREDICTED: sulfotransf ( 295) 489 117.9 2.3e-26 NP_803565 (OMIM: 171150) sulfotransferase 1A1 isof ( 295) 489 117.9 2.3e-26 XP_016879095 (OMIM: 171150) PREDICTED: sulfotransf ( 295) 489 117.9 2.3e-26 XP_005264070 (OMIM: 602385) PREDICTED: sulfotransf ( 298) 489 117.9 2.3e-26 XP_016879096 (OMIM: 171150) PREDICTED: sulfotransf ( 386) 489 118.0 2.8e-26 XP_005265734 (OMIM: 608436) PREDICTED: sulfotransf ( 296) 487 117.5 3.1e-26 NP_055280 (OMIM: 608436) sulfotransferase family c ( 296) 487 117.5 3.1e-26 XP_005265733 (OMIM: 608436) PREDICTED: sulfotransf ( 301) 485 117.0 4.3e-26 XP_016879090 (OMIM: 601292) PREDICTED: sulfotransf ( 301) 482 116.4 6.8e-26 XP_016879091 (OMIM: 601292) PREDICTED: sulfotransf ( 301) 482 116.4 6.8e-26 XP_016879089 (OMIM: 601292) PREDICTED: sulfotransf ( 301) 482 116.4 6.8e-26 XP_005265735 (OMIM: 608436) PREDICTED: sulfotransf ( 277) 481 116.1 7.4e-26 NP_005411 (OMIM: 600043) estrogen sulfotransferase ( 294) 473 114.4 2.7e-25 NP_001008743 (OMIM: 617151) sulfotransferase 1C3 i ( 304) 470 113.7 4.4e-25 XP_016859644 (OMIM: 617151) PREDICTED: sulfotransf ( 349) 470 113.7 4.9e-25 XP_016879098 (OMIM: 171150) PREDICTED: sulfotransf ( 301) 468 113.2 5.9e-25 XP_016879097 (OMIM: 171150) PREDICTED: sulfotransf ( 301) 468 113.2 5.9e-25 XP_016879093 (OMIM: 171150) PREDICTED: sulfotransf ( 301) 468 113.2 5.9e-25 XP_016879094 (OMIM: 171150) PREDICTED: sulfotransf ( 301) 468 113.2 5.9e-25 XP_016879099 (OMIM: 171150) PREDICTED: sulfotransf ( 301) 468 113.2 5.9e-25 NP_001307807 (OMIM: 617151) sulfotransferase 1C3 i ( 304) 451 109.5 8.3e-24 XP_016859642 (OMIM: 617151) PREDICTED: sulfotransf ( 349) 451 109.5 9.2e-24 XP_016859643 (OMIM: 617151) PREDICTED: sulfotransf ( 349) 451 109.5 9.2e-24 NP_004596 (OMIM: 604125) sulfotransferase family c ( 350) 436 106.1 9.4e-23 NP_814444 (OMIM: 604125) sulfotransferase family c ( 365) 436 106.2 9.8e-23 NP_003158 (OMIM: 125263) bile salt sulfotransferas ( 285) 423 103.2 6e-22 NP_001027549 (OMIM: 617152) sulfotransferase 6B1 [ ( 265) 380 93.6 4.3e-19 XP_011530175 (OMIM: 608436) PREDICTED: sulfotransf ( 237) 379 93.3 4.6e-19 XP_016859296 (OMIM: 608357) PREDICTED: sulfotransf ( 212) 374 92.2 9.2e-19 XP_011530512 (OMIM: 600043) PREDICTED: estrogen su ( 181) 334 83.2 3.9e-16 NP_789795 (OMIM: 602385) sulfotransferase 1C2 isof ( 307) 295 74.6 2.5e-13 NP_803880 (OMIM: 171150) sulfotransferase 1A1 isof ( 217) 269 68.8 1.1e-11 XP_016879092 (OMIM: 601292) PREDICTED: sulfotransf ( 221) 233 60.7 2.8e-09 XP_006721140 (OMIM: 601292) PREDICTED: sulfotransf ( 262) 154 43.1 0.00065 NP_001308699 (OMIM: 608357) sulfotransferase 1C4 i ( 227) 146 41.3 0.002 >>NP_055166 (OMIM: 608359) sulfotransferase 4A1 [Homo sa (284 aa) initn: 1968 init1: 1968 opt: 1968 Z-score: 2378.5 bits: 448.0 E(85289): 9.6e-126 Smith-Waterman score: 1968; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA 190 200 210 220 230 240 250 260 270 280 pF1KB5 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL :::::::::::::::::::::::::::::::::::::::::::: NP_055 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 250 260 270 280 >>XP_011528422 (OMIM: 608359) PREDICTED: sulfotransferas (171 aa) initn: 1178 init1: 1160 opt: 1160 Z-score: 1407.2 bits: 267.5 E(85289): 1.2e-71 Smith-Waterman score: 1160; 99.4% identity (99.4% similar) in 171 aa overlap (1-171:1-171) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ ::::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKHG 130 140 150 160 170 190 200 210 220 230 240 pF1KB5 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA >>XP_011528423 (OMIM: 608359) PREDICTED: sulfotransferas (171 aa) initn: 1189 init1: 809 opt: 809 Z-score: 983.9 bits: 189.2 E(85289): 4.6e-48 Smith-Waterman score: 967; 59.9% identity (60.2% similar) in 284 aa overlap (1-284:1-171) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKS---- 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPGLDIIKELTSPRLIKSHLPYRFLPSD XP_011 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB5 LHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQ .:::::::::: XP_011 -------------------------------------------------VGYGSWFEHVQ 60 190 200 210 220 230 240 pF1KB5 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQLVDQCCNA 70 80 90 100 110 120 250 260 270 280 pF1KB5 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL :::::::::::::::::::::::::::::::::::::::::::: XP_011 EALPVGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDFYL 130 140 150 160 170 >>NP_808220 (OMIM: 600641) sulfotransferase 1A3 [Homo sa (295 aa) initn: 603 init1: 371 opt: 523 Z-score: 635.5 bits: 125.5 E(85289): 1.2e-28 Smith-Waterman score: 604; 36.7% identity (63.3% similar) in 275 aa overlap (24-280:17-291) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :: : . . . .: .::.:. : :::::::. NP_808 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTW 10 20 30 40 50 70 80 90 100 110 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRF ..... .. ::.: .. . : ..: :: .:: :. .:. ::::::::: . NP_808 VSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLAL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWF ::. : . ::.:.::::::..::::.::: .. ::.. : ..:: ...::::. NP_808 LPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC------ .::::.:: ::.: ::::... .... .:.: : . .. ...: NP_808 QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMK 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 ------HQLVDQCCNAEAL-PVGR-GRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDF . : : ... : : : .: :: :::..::.:: : .::. :.:.: NP_808 KNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRS 240 250 260 270 280 290 pF1KB5 YL NP_808 EL >>NP_001017390 (OMIM: 615819) sulfotransferase 1A4 [Homo (295 aa) initn: 603 init1: 371 opt: 523 Z-score: 635.5 bits: 125.5 E(85289): 1.2e-28 Smith-Waterman score: 604; 36.7% identity (63.3% similar) in 275 aa overlap (24-280:17-291) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :: : . . . .: .::.:. : :::::::. NP_001 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTW 10 20 30 40 50 70 80 90 100 110 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRF ..... .. ::.: .. . : ..: :: .:: :. .:. ::::::::: . NP_001 VSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLAL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWF ::. : . ::.:.::::::..::::.::: .. ::.. : ..:: ...::::. NP_001 LPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC------ .::::.:: ::.: ::::... .... .:.: : . .. ...: NP_001 QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMK 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 ------HQLVDQCCNAEAL-PVGR-GRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDF . : : ... : : : .: :: :::..::.:: : .::. :.:.: NP_001 KNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRS 240 250 260 270 280 290 pF1KB5 YL NP_001 EL >>NP_001045 (OMIM: 601292) sulfotransferase 1A2 [Homo sa (295 aa) initn: 476 init1: 378 opt: 501 Z-score: 608.9 bits: 120.6 E(85289): 3.5e-27 Smith-Waterman score: 575; 34.2% identity (63.6% similar) in 275 aa overlap (24-280:17-291) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :: : . . . .: .::.:. : :::::::. NP_001 MELIQDISRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTW 10 20 30 40 50 70 80 90 100 110 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRF ..... .. ::.: .. : ..: ::. :: .. .:. .:::.:.::: . NP_001 VSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKVPGIPSGMETLKNTPAPRLLKTHLPLAL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWF ::. : . ::.:.::: ::..::::.:.. ... . ::.. : ..:: ...::::. NP_001 LPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVYPHPGTWESFLEKFMAGEVSYGSWY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC------ .::::.:: ::.: ::::... .... .:.: : . .. ..:: NP_001 QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDLMVEHTSFKEMK 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 -HQLVD------QCCNAEALPVGR-GRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDF . ... . . : : : .: :: :::..::.:: : .::. :.:.: NP_001 KNPMTNYTTVRREFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRS 240 250 260 270 280 290 pF1KB5 YL NP_001 EL >>NP_803564 (OMIM: 601292) sulfotransferase 1A2 [Homo sa (295 aa) initn: 476 init1: 378 opt: 501 Z-score: 608.9 bits: 120.6 E(85289): 3.5e-27 Smith-Waterman score: 575; 34.2% identity (63.6% similar) in 275 aa overlap (24-280:17-291) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :: : . . . .: .::.:. : :::::::. NP_803 MELIQDISRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTW 10 20 30 40 50 70 80 90 100 110 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRF ..... .. ::.: .. : ..: ::. :: .. .:. .:::.:.::: . NP_803 VSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKVPGIPSGMETLKNTPAPRLLKTHLPLAL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWF ::. : . ::.:.::: ::..::::.:.. ... . ::.. : ..:: ...::::. NP_803 LPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVYPHPGTWESFLEKFMAGEVSYGSWY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC------ .::::.:: ::.: ::::... .... .:.: : . .. ..:: NP_803 QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDLMVEHTSFKEMK 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 -HQLVD------QCCNAEALPVGR-GRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDF . ... . . : : : .: :: :::..::.:: : .::. :.:.: NP_803 KNPMTNYTTVRREFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRS 240 250 260 270 280 290 pF1KB5 YL NP_803 EL >>NP_001047 (OMIM: 602385) sulfotransferase 1C2 isoform (296 aa) initn: 496 init1: 324 opt: 499 Z-score: 606.5 bits: 120.2 E(85289): 4.8e-27 Smith-Waterman score: 569; 32.7% identity (66.2% similar) in 281 aa overlap (18-280:12-292) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL : : .:. : : . .: .: ..:.:. : ::::.::. NP_001 MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTW 10 20 30 40 50 70 80 90 100 110 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEY---PQP-GLDIIKELTSPRLIKSHLPYRF .::.: .. :..: .. :... : .:. ::: :.. : . :::..:.:: .. NP_001 IQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQPSGVEKAKAMPSPRILKTHLSTQL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWF :: .. ... : .:.::: :: .::::.:.: . . ::..:. . :.: :. .:::: NP_001 LPPSFWENNCKFLYVARNAKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC------ .::. .:: . ..::: :::..:: .... .:.: . :.. :. .... NP_001 DHVKGWWEMKDRHQILFLFYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMK 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 -HQLVDQCCNAEALP-------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDF . .... .... . .: :: ::. :::..::.:: .:..:: ...: NP_001 ENPMTNRSTVSKSILDQSISSFMRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFCM 240 250 260 270 280 290 pF1KB5 YL NP_001 EL >>NP_006579 (OMIM: 608357) sulfotransferase 1C4 isoform (302 aa) initn: 608 init1: 366 opt: 493 Z-score: 599.1 bits: 118.8 E(85289): 1.2e-26 Smith-Waterman score: 579; 34.0% identity (61.3% similar) in 300 aa overlap (1-282:1-300) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :: . : . : . . .:. : ..: :: ..:.:. : ::::.::. NP_006 MALHDMEDFTFDGTKRLSVNYVKGILQPTDTCDIWDKIWNFQAKPDDLLISTYPKAGTTW 10 20 30 40 50 60 70 80 90 100 110 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQP----GLDIIKELTSPRLIKSHLPYRF ::.: :... .: .. ...: ::. : ::. . . :::..:.:::... NP_006 TQEIVELIQNEGDVEKSKRAPTHQRFPFLEMKIPSLGSGLEQAHAMPSPRILKTHLPFHL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 LPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWF :: .: . . :.::.:::::: .::::.:.: ... ::..:. . :. :. .::: NP_006 LPPSLLEKNCKIIYVARNPKDNMVSYYHFQRMNKALPAPGTWEEYFETFLAGKVCWGSWH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCH-QLVD :::. .:: . .:.: ::::... ...::.:.: . : :. .... ... NP_006 EHVKGWWEAKDKHRILYLFYEDMKKNPKHEIQKLAEFIGKKLDDKVLDKIVHYTSFDVMK 190 200 210 220 230 240 240 250 260 270 280 pF1KB5 QC--CNAEALP-----------VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDF : : ..: . .: :: :: :::..::.:: ::.:: ::: : NP_006 QNPMANYSSIPAEIMDHSISPFMRKGAVGDWKKHFTVAQNERFDEDYKKKMTDTRLTFHF 250 260 270 280 290 300 pF1KB5 YL NP_006 QF >>XP_016879100 (OMIM: 171150) PREDICTED: sulfotransferas (295 aa) initn: 554 init1: 317 opt: 489 Z-score: 594.5 bits: 117.9 E(85289): 2.3e-26 Smith-Waterman score: 570; 34.5% identity (62.9% similar) in 275 aa overlap (24-280:17-291) 10 20 30 40 50 60 pF1KB5 MAESEAETPSTPGEFESKYFEFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSL :: : . . . .: .::.:. : :::::::. XP_016 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTW 10 20 30 40 50 70 80 90 100 110 pF1KB5 LQEVVYLVSQGADPDEIGLMNIDEQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRF ..... .. ::.: .. : ..: ::. :: .. .:. .:::.:.::: . XP_016 VSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLAL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB5 LPSDLHNGDSKVIYMARNPKDLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWF ::. : . ::.:.::: ::..::::.:.. .. ::.. : ..:: ...::::. XP_016 LPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB5 EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC------ .::::.:: ::.: ::::... .... .:.: : . .. ...: XP_016 QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMK 180 190 200 210 220 230 240 250 260 270 280 pF1KB5 ------HQLVDQCCNAEAL-PVGR-GRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTFDF . : : ... : : : .: :: :::..::.:: : .::. :.:.: XP_016 KNPMTNYTTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRS 240 250 260 270 280 290 pF1KB5 YL XP_016 EL 284 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:44:35 2016 done: Sat Nov 5 21:44:37 2016 Total Scan time: 7.080 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]