FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5034, 316 aa 1>>>pF1KB5034 316 - 316 aa - 316 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7926+/-0.000955; mu= 13.3909+/- 0.057 mean_var=71.2824+/-13.709, 0's: 0 Z-trim(105.1): 17 B-trim: 0 in 0/51 Lambda= 0.151909 statistics sampled from 8223 (8231) to 8223 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.253), width: 16 Scan time: 2.580 The best scores are: opt bits E(32554) CCDS10517.1 HMOX2 gene_id:3163|Hs108|chr16 ( 316) 2072 463.3 1.1e-130 CCDS73818.1 HMOX2 gene_id:3163|Hs108|chr16 ( 370) 2072 463.3 1.3e-130 CCDS66931.1 HMOX2 gene_id:3163|Hs108|chr16 ( 287) 1896 424.7 4.2e-119 CCDS13914.1 HMOX1 gene_id:3162|Hs108|chr22 ( 288) 837 192.6 3.1e-49 >>CCDS10517.1 HMOX2 gene_id:3163|Hs108|chr16 (316 aa) initn: 2072 init1: 2072 opt: 2072 Z-score: 2459.5 bits: 463.3 E(32554): 1.1e-130 Smith-Waterman score: 2072; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316) 10 20 30 40 50 60 pF1KB5 MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 NIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 WEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 WEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 GEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 GSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFIL 250 260 270 280 290 300 310 pF1KB5 AAGVALAAGLLAWYYM :::::::::::::::: CCDS10 AAGVALAAGLLAWYYM 310 >>CCDS73818.1 HMOX2 gene_id:3163|Hs108|chr16 (370 aa) initn: 2072 init1: 2072 opt: 2072 Z-score: 2458.4 bits: 463.3 E(32554): 1.3e-130 Smith-Waterman score: 2072; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:55-370) 10 20 30 pF1KB5 MSAEVETSEGVDESEKKNSGALEKENQMRM :::::::::::::::::::::::::::::: CCDS73 GSRDSPASASCVAGITGPEEREQQEPHPAAMSAEVETSEGVDESEKKNSGALEKENQMRM 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB5 ADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 ADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKD 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB5 HPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 HPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB5 AHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 AHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALD 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB5 LNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAA 270 280 290 300 310 320 280 290 300 310 pF1KB5 EQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVALAAGLLAWYYM :::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVALAAGLLAWYYM 330 340 350 360 370 >>CCDS66931.1 HMOX2 gene_id:3163|Hs108|chr16 (287 aa) initn: 1896 init1: 1896 opt: 1896 Z-score: 2251.7 bits: 424.7 E(32554): 4.2e-119 Smith-Waterman score: 1896; 100.0% identity (100.0% similar) in 287 aa overlap (30-316:1-287) 10 20 30 40 50 60 pF1KB5 MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKG ::::::::::::::::::::::::::::::: CCDS66 MADLSELLKEGTKEAHDRAENTQFVKDFLKG 10 20 30 70 80 90 100 110 120 pF1KB5 NIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 NIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGEN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB5 WEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 WEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPST 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB5 GEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQA 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB5 GSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFIL 220 230 240 250 260 270 310 pF1KB5 AAGVALAAGLLAWYYM :::::::::::::::: CCDS66 AAGVALAAGLLAWYYM 280 >>CCDS13914.1 HMOX1 gene_id:3162|Hs108|chr22 (288 aa) initn: 837 init1: 837 opt: 837 Z-score: 997.4 bits: 192.6 E(32554): 3.1e-49 Smith-Waterman score: 837; 56.2% identity (83.2% similar) in 208 aa overlap (32-239:12-219) 10 20 30 40 50 60 pF1KB5 SAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGN :::: :::.:::.: .:::..:...: ::. CCDS13 MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQ 10 20 30 40 70 80 90 100 110 120 pF1KB5 IKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENW . .. :::. ..:: : :::::.::::. :.:::.::: ::::: :: .:. ...: : CCDS13 VTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRW 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB5 EEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTG .: . : :.::.:.: .:..:::::::::::::.:::::::::::.::.:: :::.: CCDS13 QEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 EGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAG :: :. : :. .: .::::::.:::.:... ...:..:::. :: :.:.:.::.. CCDS13 EGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 STLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILA CCDS13 THDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATV 230 240 250 260 270 280 316 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:37:57 2016 done: Sat Nov 5 19:37:57 2016 Total Scan time: 2.580 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]