FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5035, 192 aa 1>>>pF1KB5035 192 - 192 aa - 192 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0079+/-0.000744; mu= 5.9034+/- 0.045 mean_var=114.7843+/-22.616, 0's: 0 Z-trim(112.5): 30 B-trim: 0 in 0/51 Lambda= 0.119711 statistics sampled from 13207 (13233) to 13207 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.406), width: 16 Scan time: 2.210 The best scores are: opt bits E(32554) CCDS7564.2 MXI1 gene_id:4601|Hs108|chr10 ( 228) 1240 224.1 4.9e-59 CCDS7563.1 MXI1 gene_id:4601|Hs108|chr10 ( 295) 1240 224.2 6.1e-59 CCDS31284.1 MXI1 gene_id:4601|Hs108|chr10 ( 182) 979 179.0 1.5e-45 CCDS1896.1 MXD1 gene_id:4084|Hs108|chr2 ( 221) 672 126.0 1.6e-29 CCDS56123.1 MXD1 gene_id:4084|Hs108|chr2 ( 211) 602 113.9 6.8e-26 CCDS3361.1 MXD4 gene_id:10608|Hs108|chr4 ( 209) 529 101.3 4.2e-22 CCDS4416.1 MXD3 gene_id:83463|Hs108|chr5 ( 206) 427 83.7 8.3e-17 CCDS47347.1 MXD3 gene_id:83463|Hs108|chr5 ( 193) 370 73.8 7.2e-14 >>CCDS7564.2 MXI1 gene_id:4601|Hs108|chr10 (228 aa) initn: 1240 init1: 1240 opt: 1240 Z-score: 1173.4 bits: 224.1 E(32554): 4.9e-59 Smith-Waterman score: 1240; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:37-228) 10 20 30 pF1KB5 MPSPRLQHSKPPRRLSRAQKHSSGSSNTST :::::::::::::::::::::::::::::: CCDS75 INVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTST 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF 130 140 150 160 170 180 160 170 180 190 pF1KB5 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS :::::::::::::::::::::::::::::::::::::::::: CCDS75 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS 190 200 210 220 >>CCDS7563.1 MXI1 gene_id:4601|Hs108|chr10 (295 aa) initn: 1240 init1: 1240 opt: 1240 Z-score: 1171.7 bits: 224.2 E(32554): 6.1e-59 Smith-Waterman score: 1240; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:104-295) 10 20 30 pF1KB5 MPSPRLQHSKPPRRLSRAQKHSSGSSNTST :::::::::::::::::::::::::::::: CCDS75 QILLEAASYLEQIEKENKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTST 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB5 ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS 140 150 160 170 180 190 100 110 120 130 140 150 pF1KB5 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF 200 210 220 230 240 250 160 170 180 190 pF1KB5 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS :::::::::::::::::::::::::::::::::::::::::: CCDS75 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS 260 270 280 290 >>CCDS31284.1 MXI1 gene_id:4601|Hs108|chr10 (182 aa) initn: 970 init1: 970 opt: 979 Z-score: 931.2 bits: 179.0 E(32554): 1.5e-45 Smith-Waterman score: 1146; 94.8% identity (94.8% similar) in 192 aa overlap (1-192:1-182) 10 20 30 40 50 60 pF1KB5 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPL ::::::::::::::::::::::::::::::::: ::::::::::::::::: CCDS31 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANR----------RAHLRLCLERLKVLIPL 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 GPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB5 RMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEG 120 130 140 150 160 170 190 pF1KB5 YSSASVKLSFTS :::::::::::: CCDS31 YSSASVKLSFTS 180 >>CCDS1896.1 MXD1 gene_id:4084|Hs108|chr2 (221 aa) initn: 646 init1: 377 opt: 672 Z-score: 643.4 bits: 126.0 E(32554): 1.6e-29 Smith-Waterman score: 672; 61.8% identity (87.6% similar) in 170 aa overlap (18-187:43-207) 10 20 30 40 pF1KB5 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHL : :. . :.......::::::.:::::::: CCDS18 LEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRSTHNEMEKNRRAHL 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB5 RLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWR :::::.:: :.::::. .:::::.::.::: ::::::. .::. ::...:.:::: :: . CCDS18 RLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQREQRHLKRQ 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB5 LEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDID ::.: .:::::::::::.::.::::.::::.::::::.. :..: :..:.:: : CCDS18 LEKLG----IERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLD-WSSSSVSDSD 140 150 160 170 180 170 180 190 pF1KB5 DHSSLPSIGSDEGYSSASVKLSFTS ...:. :.::::::::.:.: CCDS18 ERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL 190 200 210 220 >>CCDS56123.1 MXD1 gene_id:4084|Hs108|chr2 (211 aa) initn: 606 init1: 315 opt: 602 Z-score: 578.4 bits: 113.9 E(32554): 6.8e-26 Smith-Waterman score: 602; 62.2% identity (87.2% similar) in 156 aa overlap (32-187:48-197) 10 20 30 40 50 60 pF1KB5 PSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLG :.: .:. ..::::::::::.:: :.::: CCDS56 YLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNN-SSSRRAHLRLCLEKLKGLVPLG 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB5 PDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIR :. .:::::.::.::: ::::::. .::. ::...:.:::: :: .::.: : .:::: CCDS56 PESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQREQRHLKRQLEKL-G---IERIR 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB5 MDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGY :::::::.::.::::.::::.::::::.. :..: :..:.:: :...:. :.:::::: CCDS56 MDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLD-WSSSSVSDSDERGSMQSLGSDEGY 140 150 160 170 180 190 190 pF1KB5 SSASVKLSFTS ::.:.: CCDS56 SSTSIKRIKLQDSHKACLGL 200 210 >>CCDS3361.1 MXD4 gene_id:10608|Hs108|chr4 (209 aa) initn: 538 init1: 346 opt: 529 Z-score: 510.3 bits: 101.3 E(32554): 4.2e-22 Smith-Waterman score: 529; 52.0% identity (76.6% similar) in 175 aa overlap (15-188:37-203) 10 20 30 40 pF1KB5 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRR ..: . ...: . :::.::::::.:: CCDS33 LILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 AHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFL :.::: ::.:: :.::::: ::::::.::..::.::::::: .:.. :.:..:.::: CCDS33 AKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB5 KWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSIS : :::::. : .::.: :: ::..:.: :::.: ::.:. ::. ::.:..... : CCDS33 KRRLEQLS-VQSVERVRTDSTGSAVSTD--DSEQE---VDIEGMEFGPGELDSVGSS--S 130 140 150 160 170 170 180 190 pF1KB5 DIDDHSSLPS-IGSDEGYSSASVKLSFTS : ::: :: : :.: :.. .: CCDS33 DADDHYSLQSGTGGDSGFGPHCRRLGRPALS 180 190 200 >>CCDS4416.1 MXD3 gene_id:83463|Hs108|chr5 (206 aa) initn: 381 init1: 297 opt: 427 Z-score: 415.2 bits: 83.7 E(32554): 8.3e-17 Smith-Waterman score: 427; 47.7% identity (76.2% similar) in 151 aa overlap (10-156:36-185) 10 20 30 pF1KB5 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNEL . : . : .:. . ... ..::.:::: CCDS44 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 EKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLER :: :::.:. :::::: .::: ::.:.:::.:: .:. ::.:::. :..... : :. CCDS44 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 EQRFLKWRLEQLQG---PQEMERIRMDSIGST-ISSDRSDSEREEIEVDVESTEFSHGEV .:. :. .::::.: : ::.: ::. :. .::.::::..::.:::::: :. ::. CCDS44 KQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFG-GEA 130 140 150 160 170 180 160 170 180 190 pF1KB5 DNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS . CCDS44 ELLRGFVAGQEHSYSHGGGAWL 190 200 >>CCDS47347.1 MXD3 gene_id:83463|Hs108|chr5 (193 aa) initn: 356 init1: 297 opt: 370 Z-score: 362.4 bits: 73.8 E(32554): 7.2e-14 Smith-Waterman score: 370; 45.9% identity (75.2% similar) in 133 aa overlap (10-138:36-168) 10 20 30 pF1KB5 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNEL . : . : .:. . ... ..::.:::: CCDS47 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB5 EKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLER :: :::.:. :::::: .::: ::.:.:::.:: .:. ::.:::. :..... : :. CCDS47 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB5 EQRFLKWRLEQLQG---PQEMERIRMDSIGST-ISSDRSDSEREEIEVDVESTEFSHGEV .:. :. .::::.: : ::.: ::. :. .::.::::.. CCDS47 KQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQVLPNENGGTPNHRPTGR 130 140 150 160 170 180 160 170 180 190 pF1KB5 DNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS CCDS47 GNNISSHH 190 192 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:27:03 2016 done: Fri Nov 4 20:27:03 2016 Total Scan time: 2.210 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]