FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5057, 533 aa 1>>>pF1KB5057 533 - 533 aa - 533 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7482+/-0.00041; mu= 16.2180+/- 0.025 mean_var=72.5481+/-15.105, 0's: 0 Z-trim(111.5): 52 B-trim: 1814 in 2/48 Lambda= 0.150578 statistics sampled from 20084 (20136) to 20084 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.236), width: 16 Scan time: 10.460 The best scores are: opt bits E(85289) NP_006614 (OMIM: 256520,601815,606879) D-3-phospho ( 533) 3482 766.1 0 XP_011539533 (OMIM: 256520,601815,606879) PREDICTE ( 435) 2734 603.6 4e-172 XP_011539530 (OMIM: 256520,601815,606879) PREDICTE ( 570) 2734 603.6 5.1e-172 XP_011539529 (OMIM: 256520,601815,606879) PREDICTE ( 581) 2734 603.6 5.2e-172 XP_011539528 (OMIM: 256520,601815,606879) PREDICTE ( 607) 2734 603.6 5.4e-172 XP_011511698 (OMIM: 194190,602618) PREDICTED: C-te ( 430) 484 114.8 5.5e-25 XP_011511697 (OMIM: 194190,602618) PREDICTED: C-te ( 430) 484 114.8 5.5e-25 XP_016863252 (OMIM: 194190,602618) PREDICTED: C-te ( 430) 484 114.8 5.5e-25 XP_005272320 (OMIM: 194190,602618) PREDICTED: C-te ( 430) 484 114.8 5.5e-25 XP_016863251 (OMIM: 194190,602618) PREDICTED: C-te ( 430) 484 114.8 5.5e-25 XP_005272318 (OMIM: 194190,602618) PREDICTED: C-te ( 441) 484 114.8 5.6e-25 XP_016863254 (OMIM: 194190,602618) PREDICTED: C-te ( 429) 482 114.3 7.4e-25 XP_016863253 (OMIM: 194190,602618) PREDICTED: C-te ( 429) 482 114.3 7.4e-25 NP_001012632 (OMIM: 194190,602618) C-terminal-bind ( 429) 482 114.3 7.4e-25 XP_016863256 (OMIM: 194190,602618) PREDICTED: C-te ( 429) 482 114.3 7.4e-25 XP_016863255 (OMIM: 194190,602618) PREDICTED: C-te ( 429) 482 114.3 7.4e-25 NP_001319 (OMIM: 194190,602618) C-terminal-binding ( 440) 482 114.3 7.6e-25 XP_011511699 (OMIM: 194190,602618) PREDICTED: C-te ( 367) 476 113.0 1.6e-24 NP_036335 (OMIM: 260000,604296) glyoxylate reducta ( 328) 467 111.0 5.6e-24 XP_011537660 (OMIM: 602619) PREDICTED: C-terminal- ( 420) 467 111.1 7e-24 XP_011537659 (OMIM: 602619) PREDICTED: C-terminal- ( 420) 467 111.1 7e-24 XP_005269618 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_016871245 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_011537655 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_005269629 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_016871246 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_011537656 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 NP_001307943 (OMIM: 602619) C-terminal-binding pro ( 445) 467 111.1 7.4e-24 NP_001077383 (OMIM: 602619) C-terminal-binding pro ( 445) 467 111.1 7.4e-24 NP_001277143 (OMIM: 602619) C-terminal-binding pro ( 445) 467 111.1 7.4e-24 XP_011537653 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_006717705 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_005269624 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 NP_001307942 (OMIM: 602619) C-terminal-binding pro ( 445) 467 111.1 7.4e-24 NP_001307941 (OMIM: 602619) C-terminal-binding pro ( 445) 467 111.1 7.4e-24 XP_005269625 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_005269621 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_011537657 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 NP_001320 (OMIM: 602619) C-terminal-binding protei ( 445) 467 111.1 7.4e-24 XP_005269628 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 NP_001277144 (OMIM: 602619) C-terminal-binding pro ( 445) 467 111.1 7.4e-24 XP_005269626 (OMIM: 602619) PREDICTED: C-terminal- ( 445) 467 111.1 7.4e-24 XP_011537651 (OMIM: 602619) PREDICTED: C-terminal- ( 513) 467 111.1 8.3e-24 NP_073713 (OMIM: 602619) C-terminal-binding protei ( 985) 467 111.2 1.5e-23 XP_016870810 (OMIM: 260000,604296) PREDICTED: glyo ( 309) 438 104.7 4.2e-22 XP_016870809 (OMIM: 260000,604296) PREDICTED: glyo ( 338) 426 102.1 2.8e-21 XP_005251688 (OMIM: 260000,604296) PREDICTED: glyo ( 221) 358 87.3 5.4e-17 XP_016870811 (OMIM: 260000,604296) PREDICTED: glyo ( 231) 317 78.4 2.7e-14 XP_011516375 (OMIM: 260000,604296) PREDICTED: glyo ( 194) 271 68.3 2.4e-11 XP_016870812 (OMIM: 260000,604296) PREDICTED: glyo ( 204) 230 59.4 1.2e-08 >>NP_006614 (OMIM: 256520,601815,606879) D-3-phosphoglyc (533 aa) initn: 3482 init1: 3482 opt: 3482 Z-score: 4087.9 bits: 766.1 E(85289): 0 Smith-Waterman score: 3482; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB5 MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 IPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 CLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 CLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPT 430 440 450 460 470 480 490 500 510 520 530 pF1KB5 MIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF 490 500 510 520 530 >>XP_011539533 (OMIM: 256520,601815,606879) PREDICTED: D (435 aa) initn: 2734 init1: 2734 opt: 2734 Z-score: 3211.1 bits: 603.6 E(85289): 4e-172 Smith-Waterman score: 2734; 100.0% identity (100.0% similar) in 415 aa overlap (119-533:21-435) 90 100 110 120 130 140 pF1KB5 TRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTL :::::::::::::::::::::::::::::: XP_011 MLWFKRSSPLSTAHHDLTHQRQIPQATASMKDGKWERKKFMGTELNGKTL 10 20 30 40 50 150 160 170 180 190 200 pF1KB5 GILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTP 60 70 80 90 100 110 210 220 230 240 250 260 pF1KB5 LLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPR 120 130 140 150 160 170 270 280 290 300 310 320 pF1KB5 DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPH 180 190 200 210 220 230 330 340 350 360 370 380 pF1KB5 TKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADV 240 250 260 270 280 290 390 400 410 420 430 440 pF1KB5 NLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGL 300 310 320 330 340 350 450 460 470 480 490 500 pF1KB5 NGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHV 360 370 380 390 400 410 510 520 530 pF1KB5 MGISSLLPSLEAWKQHVTEAFQFHF ::::::::::::::::::::::::: XP_011 MGISSLLPSLEAWKQHVTEAFQFHF 420 430 >>XP_011539530 (OMIM: 256520,601815,606879) PREDICTED: D (570 aa) initn: 2734 init1: 2734 opt: 2734 Z-score: 3209.2 bits: 603.6 E(85289): 5.1e-172 Smith-Waterman score: 3041; 86.9% identity (86.9% similar) in 563 aa overlap (45-533:8-570) 20 30 40 50 60 70 pF1KB5 LDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVG :::::::::::::::::::::::::::::: XP_011 MCSISFILQDCEGLIVRSATKVTADVINAAEKLQVVG 10 20 30 80 90 100 110 pF1KB5 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLAR--------------- ::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARPETFRDQEITFPMAR 40 50 60 70 80 90 120 pF1KB5 -----------------------------------------------------------Q : XP_011 PAFPPAGGGSGGIYLCSNSSLQFPSELSGPALFKGIGEMLWFKRSSPLSTAHHDLTHQRQ 100 110 120 130 140 150 130 140 150 160 170 180 pF1KB5 IPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISP 160 170 180 190 200 210 190 200 210 220 230 240 pF1KB5 EVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIV 220 230 240 250 260 270 250 260 270 280 290 300 pF1KB5 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIA 280 290 300 310 320 330 310 320 330 340 350 360 pF1KB5 VQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG 340 350 360 370 380 390 370 380 390 400 410 420 pF1KB5 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE 400 410 420 430 440 450 430 440 450 460 470 480 pF1KB5 CLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPT 460 470 480 490 500 510 490 500 510 520 530 pF1KB5 MIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF 520 530 540 550 560 570 >>XP_011539529 (OMIM: 256520,601815,606879) PREDICTED: D (581 aa) initn: 2734 init1: 2734 opt: 2734 Z-score: 3209.1 bits: 603.6 E(85289): 5.2e-172 Smith-Waterman score: 3031; 86.7% identity (86.8% similar) in 562 aa overlap (46-533:20-581) 20 30 40 50 60 70 pF1KB5 DPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGR .::::::::::::::::::::::::::::: XP_011 MQDCSVLSPPLCLLGAFGGKDCEGLIVRSATKVTADVINAAEKLQVVGR 10 20 30 40 80 90 100 110 pF1KB5 AGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLAR---------------- :::::::::::::::::::::::::::::::::::::::::::: XP_011 AGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARPETFRDQEITFPMARP 50 60 70 80 90 100 120 pF1KB5 ----------------------------------------------------------QI :: XP_011 AFPPAGGGSGGIYLCSNSSLQFPSELSGPALFKGIGEMLWFKRSSPLSTAHHDLTHQRQI 110 120 130 140 150 160 130 140 150 160 170 180 pF1KB5 PQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPE 170 180 190 200 210 220 190 200 210 220 230 240 pF1KB5 VSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVD 230 240 250 260 270 280 250 260 270 280 290 300 pF1KB5 EGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAV 290 300 310 320 330 340 310 320 330 340 350 360 pF1KB5 QFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGT 350 360 370 380 390 400 370 380 390 400 410 420 pF1KB5 SLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGEC 410 420 430 440 450 460 430 440 450 460 470 480 pF1KB5 LLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTM 470 480 490 500 510 520 490 500 510 520 530 pF1KB5 IGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF 530 540 550 560 570 580 >>XP_011539528 (OMIM: 256520,601815,606879) PREDICTED: D (607 aa) initn: 2734 init1: 2734 opt: 2734 Z-score: 3208.8 bits: 603.6 E(85289): 5.4e-172 Smith-Waterman score: 3052; 86.9% identity (86.9% similar) in 565 aa overlap (43-533:43-607) 20 30 40 50 60 70 pF1KB5 DSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQV :::::::::::::::::::::::::::::: XP_011 DSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQV 20 30 40 50 60 70 80 90 100 110 pF1KB5 VGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLAR------------- ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARPETFRDQEITFPM 80 90 100 110 120 130 pF1KB5 ------------------------------------------------------------ XP_011 ARPAFPPAGGGSGGIYLCSNSSLQFPSELSGPALFKGIGEMLWFKRSSPLSTAHHDLTHQ 140 150 160 170 180 190 120 130 140 150 160 170 pF1KB5 -QIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPII ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPII 200 210 220 230 240 250 180 190 200 210 220 230 pF1KB5 SPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGG 260 270 280 290 300 310 240 250 260 270 280 290 pF1KB5 IVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEE 320 330 340 350 360 370 300 310 320 330 340 350 pF1KB5 IAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVIT 380 390 400 410 420 430 360 370 380 390 400 410 pF1KB5 QGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGF 440 450 460 470 480 490 420 430 440 450 460 470 pF1KB5 GECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAML 500 510 520 530 540 550 480 490 500 510 520 530 pF1KB5 PTMIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTMIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF 560 570 580 590 600 >-- initn: 272 init1: 272 opt: 272 Z-score: 318.3 bits: 68.8 E(85289): 5.4e-11 Smith-Waterman score: 272; 100.0% identity (100.0% similar) in 42 aa overlap (1-42:1-42) 10 20 30 40 50 60 pF1KB5 MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVT :::::::::::::::::::::::::::::::::::::::::: XP_011 MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 ADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQ XP_011 ADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARP 70 80 90 100 110 120 >>XP_011511698 (OMIM: 194190,602618) PREDICTED: C-termin (430 aa) initn: 302 init1: 169 opt: 484 Z-score: 569.5 bits: 114.8 E(85289): 5.5e-25 Smith-Waterman score: 484; 31.5% identity (58.5% similar) in 330 aa overlap (45-360:56-382) 20 30 40 50 60 70 pF1KB5 LDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVG :.. : .. . .: . .. . :... XP_011 DCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIV 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB5 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDG--- : :.: ::.:...: :: : :.: .. .:. : :. : :. ....: XP_011 RIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRV 90 100 110 120 130 140 140 150 160 170 180 pF1KB5 -KWERKKFMGT---ELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFG . :. . ... .. :.::::.::::.:. :: : ..::.... ::: .: : ..: XP_011 QSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALG 150 160 170 180 190 200 190 200 210 220 230 240 pF1KB5 VQQLP-LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALL .:.. :... : .:.: : . :.:: : : ..:. .:: ::::.::: :: XP_011 LQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALA 210 220 230 240 250 260 250 260 270 280 290 300 pF1KB5 RALQSGQCAGAALDVFTEEPPR--DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFV .::. :. :::::: :: . : : :.: :: . ...:. . :: : .. XP_011 QALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIR 270 280 290 300 310 320 310 320 330 340 350 360 pF1KB5 DMVKGK---SLTGVVNAQALTSAFS-PHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG . :. :: . :: . ::.: : . : :. :.. : :.. : : XP_011 RAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGA---AYSRYPPGVVGVAPTG 330 340 350 360 370 380 370 380 390 400 410 420 pF1KB5 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE XP_011 IPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL 390 400 410 420 430 >>XP_011511697 (OMIM: 194190,602618) PREDICTED: C-termin (430 aa) initn: 302 init1: 169 opt: 484 Z-score: 569.5 bits: 114.8 E(85289): 5.5e-25 Smith-Waterman score: 484; 31.5% identity (58.5% similar) in 330 aa overlap (45-360:56-382) 20 30 40 50 60 70 pF1KB5 LDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVG :.. : .. . .: . .. . :... XP_011 DCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIV 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB5 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDG--- : :.: ::.:...: :: : :.: .. .:. : :. : :. ....: XP_011 RIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRV 90 100 110 120 130 140 140 150 160 170 180 pF1KB5 -KWERKKFMGT---ELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFG . :. . ... .. :.::::.::::.:. :: : ..::.... ::: .: : ..: XP_011 QSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALG 150 160 170 180 190 200 190 200 210 220 230 240 pF1KB5 VQQLP-LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALL .:.. :... : .:.: : . :.:: : : ..:. .:: ::::.::: :: XP_011 LQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALA 210 220 230 240 250 260 250 260 270 280 290 300 pF1KB5 RALQSGQCAGAALDVFTEEPPR--DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFV .::. :. :::::: :: . : : :.: :: . ...:. . :: : .. XP_011 QALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIR 270 280 290 300 310 320 310 320 330 340 350 360 pF1KB5 DMVKGK---SLTGVVNAQALTSAFS-PHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG . :. :: . :: . ::.: : . : :. :.. : :.. : : XP_011 RAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGA---AYSRYPPGVVGVAPTG 330 340 350 360 370 380 370 380 390 400 410 420 pF1KB5 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE XP_011 IPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL 390 400 410 420 430 >>XP_016863252 (OMIM: 194190,602618) PREDICTED: C-termin (430 aa) initn: 302 init1: 169 opt: 484 Z-score: 569.5 bits: 114.8 E(85289): 5.5e-25 Smith-Waterman score: 484; 31.5% identity (58.5% similar) in 330 aa overlap (45-360:56-382) 20 30 40 50 60 70 pF1KB5 LDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVG :.. : .. . .: . .. . :... XP_016 DCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIV 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB5 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDG--- : :.: ::.:...: :: : :.: .. .:. : :. : :. ....: XP_016 RIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRV 90 100 110 120 130 140 140 150 160 170 180 pF1KB5 -KWERKKFMGT---ELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFG . :. . ... .. :.::::.::::.:. :: : ..::.... ::: .: : ..: XP_016 QSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALG 150 160 170 180 190 200 190 200 210 220 230 240 pF1KB5 VQQLP-LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALL .:.. :... : .:.: : . :.:: : : ..:. .:: ::::.::: :: XP_016 LQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALA 210 220 230 240 250 260 250 260 270 280 290 300 pF1KB5 RALQSGQCAGAALDVFTEEPPR--DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFV .::. :. :::::: :: . : : :.: :: . ...:. . :: : .. XP_016 QALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIR 270 280 290 300 310 320 310 320 330 340 350 360 pF1KB5 DMVKGK---SLTGVVNAQALTSAFS-PHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG . :. :: . :: . ::.: : . : :. :.. : :.. : : XP_016 RAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGA---AYSRYPPGVVGVAPTG 330 340 350 360 370 380 370 380 390 400 410 420 pF1KB5 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE XP_016 IPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL 390 400 410 420 430 >>XP_005272320 (OMIM: 194190,602618) PREDICTED: C-termin (430 aa) initn: 302 init1: 169 opt: 484 Z-score: 569.5 bits: 114.8 E(85289): 5.5e-25 Smith-Waterman score: 484; 31.5% identity (58.5% similar) in 330 aa overlap (45-360:56-382) 20 30 40 50 60 70 pF1KB5 LDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVG :.. : .. . .: . .. . :... XP_005 DCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIV 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB5 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDG--- : :.: ::.:...: :: : :.: .. .:. : :. : :. ....: XP_005 RIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRV 90 100 110 120 130 140 140 150 160 170 180 pF1KB5 -KWERKKFMGT---ELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFG . :. . ... .. :.::::.::::.:. :: : ..::.... ::: .: : ..: XP_005 QSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALG 150 160 170 180 190 200 190 200 210 220 230 240 pF1KB5 VQQLP-LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALL .:.. :... : .:.: : . :.:: : : ..:. .:: ::::.::: :: XP_005 LQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALA 210 220 230 240 250 260 250 260 270 280 290 300 pF1KB5 RALQSGQCAGAALDVFTEEPPR--DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFV .::. :. :::::: :: . : : :.: :: . ...:. . :: : .. XP_005 QALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIR 270 280 290 300 310 320 310 320 330 340 350 360 pF1KB5 DMVKGK---SLTGVVNAQALTSAFS-PHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG . :. :: . :: . ::.: : . : :. :.. : :.. : : XP_005 RAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGA---AYSRYPPGVVGVAPTG 330 340 350 360 370 380 370 380 390 400 410 420 pF1KB5 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE XP_005 IPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL 390 400 410 420 430 >>XP_016863251 (OMIM: 194190,602618) PREDICTED: C-termin (430 aa) initn: 302 init1: 169 opt: 484 Z-score: 569.5 bits: 114.8 E(85289): 5.5e-25 Smith-Waterman score: 484; 31.5% identity (58.5% similar) in 330 aa overlap (45-360:56-382) 20 30 40 50 60 70 pF1KB5 LDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVG :.. : .. . .: . .. . :... XP_016 DCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIV 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB5 RAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDG--- : :.: ::.:...: :: : :.: .. .:. : :. : :. ....: XP_016 RIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRV 90 100 110 120 130 140 140 150 160 170 180 pF1KB5 -KWERKKFMGT---ELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFG . :. . ... .. :.::::.::::.:. :: : ..::.... ::: .: : ..: XP_016 QSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALG 150 160 170 180 190 200 190 200 210 220 230 240 pF1KB5 VQQLP-LEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALL .:.. :... : .:.: : . :.:: : : ..:. .:: ::::.::: :: XP_016 LQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALA 210 220 230 240 250 260 250 260 270 280 290 300 pF1KB5 RALQSGQCAGAALDVFTEEPPR--DRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFV .::. :. :::::: :: . : : :.: :: . ...:. . :: : .. XP_016 QALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIR 270 280 290 300 310 320 310 320 330 340 350 360 pF1KB5 DMVKGK---SLTGVVNAQALTSAFS-PHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQG . :. :: . :: . ::.: : . : :. :.. : :.. : : XP_016 RAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGA---AYSRYPPGVVGVAPTG 330 340 350 360 370 380 370 380 390 400 410 420 pF1KB5 TSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGE XP_016 IPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL 390 400 410 420 430 533 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:17:46 2016 done: Sat Nov 5 06:17:48 2016 Total Scan time: 10.460 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]