FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5062, 655 aa 1>>>pF1KB5062 655 - 655 aa - 655 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9889+/-0.000536; mu= 15.6805+/- 0.033 mean_var=81.2772+/-16.966, 0's: 0 Z-trim(108.0): 218 B-trim: 201 in 1/50 Lambda= 0.142262 statistics sampled from 15819 (16087) to 15819 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.525), E-opt: 0.2 (0.189), width: 16 Scan time: 10.370 The best scores are: opt bits E(85289) NP_004818 (OMIM: 138900,603756,614490) ATP-binding ( 655) 4250 883.0 0 XP_005263411 (OMIM: 138900,603756,614490) PREDICTE ( 655) 4250 883.0 0 XP_016864342 (OMIM: 138900,603756,614490) PREDICTE ( 655) 4250 883.0 0 XP_005263412 (OMIM: 138900,603756,614490) PREDICTE ( 655) 4250 883.0 0 XP_011530722 (OMIM: 138900,603756,614490) PREDICTE ( 655) 4250 883.0 0 XP_016864341 (OMIM: 138900,603756,614490) PREDICTE ( 653) 4226 878.1 0 XP_005263413 (OMIM: 138900,603756,614490) PREDICTE ( 653) 4226 878.1 0 NP_001244315 (OMIM: 138900,603756,614490) ATP-bind ( 611) 3520 733.2 6.6e-211 NP_004906 (OMIM: 603076) ATP-binding cassette sub- ( 678) 945 204.7 8.9e-52 XP_011528108 (OMIM: 603076) PREDICTED: ATP-binding ( 689) 945 204.7 9.1e-52 XP_005264540 (OMIM: 210250,605460,611465) PREDICTE ( 672) 853 185.8 4.3e-46 XP_011531332 (OMIM: 210250,605460,611465) PREDICTE ( 676) 853 185.8 4.3e-46 NP_071882 (OMIM: 210250,605460,611465) ATP-binding ( 673) 850 185.2 6.6e-46 XP_011531331 (OMIM: 210250,605460,611465) PREDICTE ( 677) 850 185.2 6.6e-46 XP_011528109 (OMIM: 603076) PREDICTED: ATP-binding ( 641) 826 180.3 1.9e-44 XP_005264537 (OMIM: 210250,605459) PREDICTED: ATP- ( 558) 670 148.2 7.4e-35 XP_006712136 (OMIM: 210250,605459) PREDICTED: ATP- ( 593) 670 148.3 7.8e-35 XP_011531326 (OMIM: 210250,605459) PREDICTED: ATP- ( 606) 670 148.3 7.9e-35 NP_071881 (OMIM: 210250,605459) ATP-binding casset ( 651) 670 148.3 8.4e-35 XP_006712137 (OMIM: 210250,605459) PREDICTED: ATP- ( 339) 642 142.4 2.6e-33 NP_997511 (OMIM: 603076) ATP-binding cassette sub- ( 644) 620 138.0 1e-31 NP_997512 (OMIM: 603076) ATP-binding cassette sub- ( 663) 620 138.0 1.1e-31 NP_058198 (OMIM: 603076) ATP-binding cassette sub- ( 666) 620 138.0 1.1e-31 NP_997510 (OMIM: 603076) ATP-binding cassette sub- ( 668) 620 138.0 1.1e-31 NP_997057 (OMIM: 603076) ATP-binding cassette sub- ( 677) 620 138.0 1.1e-31 NP_071452 (OMIM: 607784) ATP-binding cassette sub- ( 646) 613 136.6 2.8e-31 NP_001135977 (OMIM: 607784) ATP-binding cassette s ( 646) 613 136.6 2.8e-31 XP_011531327 (OMIM: 210250,605459) PREDICTED: ATP- ( 570) 605 134.9 7.8e-31 XP_011541254 (OMIM: 607784) PREDICTED: ATP-binding ( 582) 598 133.5 2.2e-30 XP_016873610 (OMIM: 607784) PREDICTED: ATP-binding ( 585) 598 133.5 2.2e-30 XP_011531329 (OMIM: 210250,605459) PREDICTED: ATP- ( 480) 445 102.0 5.2e-21 XP_011531328 (OMIM: 210250,605459) PREDICTED: ATP- ( 561) 344 81.3 1e-14 XP_016879504 (OMIM: 612507) PREDICTED: ATP-binding (1476) 317 76.0 1.1e-12 NP_525022 (OMIM: 612507) ATP-binding cassette sub- (1624) 317 76.0 1.2e-12 XP_016879502 (OMIM: 612507) PREDICTED: ATP-binding (1626) 317 76.0 1.2e-12 XP_016879501 (OMIM: 612507) PREDICTED: ATP-binding (1626) 317 76.0 1.2e-12 XP_016879503 (OMIM: 612507) PREDICTED: ATP-binding (1626) 317 76.0 1.2e-12 XP_016879500 (OMIM: 612507) PREDICTED: ATP-binding (1632) 317 76.0 1.2e-12 XP_011522494 (OMIM: 612505) PREDICTED: ATP-binding (1063) 304 73.3 5.3e-12 XP_011522493 (OMIM: 612505) PREDICTED: ATP-binding (1164) 304 73.3 5.7e-12 XP_005256997 (OMIM: 612505) PREDICTED: ATP-binding (1560) 304 73.3 7.3e-12 NP_001275915 (OMIM: 612505) ATP-binding cassette s (1616) 304 73.3 7.5e-12 XP_005256995 (OMIM: 612505) PREDICTED: ATP-binding (1621) 304 73.3 7.5e-12 NP_001275914 (OMIM: 612505) ATP-binding cassette s (1621) 304 73.3 7.5e-12 XP_011513444 (OMIM: 607807) PREDICTED: ATP-binding (4298) 308 74.4 9.8e-12 XP_011513443 (OMIM: 607807) PREDICTED: ATP-binding (4329) 308 74.4 9.8e-12 XP_016867257 (OMIM: 607807) PREDICTED: ATP-binding (4396) 308 74.4 1e-11 XP_016867256 (OMIM: 607807) PREDICTED: ATP-binding (4433) 308 74.4 1e-11 XP_011513441 (OMIM: 607807) PREDICTED: ATP-binding (4456) 308 74.4 1e-11 XP_011513440 (OMIM: 607807) PREDICTED: ATP-binding (4468) 308 74.4 1e-11 >>NP_004818 (OMIM: 138900,603756,614490) ATP-binding cas (655 aa) initn: 4250 init1: 4250 opt: 4250 Z-score: 4716.7 bits: 883.0 E(85289): 0 Smith-Waterman score: 4250; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655) 10 20 30 40 50 60 pF1KB5 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS 610 620 630 640 650 >>XP_005263411 (OMIM: 138900,603756,614490) PREDICTED: A (655 aa) initn: 4250 init1: 4250 opt: 4250 Z-score: 4716.7 bits: 883.0 E(85289): 0 Smith-Waterman score: 4250; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655) 10 20 30 40 50 60 pF1KB5 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS 610 620 630 640 650 >>XP_016864342 (OMIM: 138900,603756,614490) PREDICTED: A (655 aa) initn: 4250 init1: 4250 opt: 4250 Z-score: 4716.7 bits: 883.0 E(85289): 0 Smith-Waterman score: 4250; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655) 10 20 30 40 50 60 pF1KB5 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS 610 620 630 640 650 >>XP_005263412 (OMIM: 138900,603756,614490) PREDICTED: A (655 aa) initn: 4250 init1: 4250 opt: 4250 Z-score: 4716.7 bits: 883.0 E(85289): 0 Smith-Waterman score: 4250; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655) 10 20 30 40 50 60 pF1KB5 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS 610 620 630 640 650 >>XP_011530722 (OMIM: 138900,603756,614490) PREDICTED: A (655 aa) initn: 4250 init1: 4250 opt: 4250 Z-score: 4716.7 bits: 883.0 E(85289): 0 Smith-Waterman score: 4250; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655) 10 20 30 40 50 60 pF1KB5 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN 550 560 570 580 590 600 610 620 630 640 650 pF1KB5 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS 610 620 630 640 650 >>XP_016864341 (OMIM: 138900,603756,614490) PREDICTED: A (653 aa) initn: 4226 init1: 2207 opt: 4226 Z-score: 4690.1 bits: 878.1 E(85289): 0 Smith-Waterman score: 4226; 99.7% identity (99.7% similar) in 655 aa overlap (1-655:1-653) 10 20 30 40 50 60 pF1KB5 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK :::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_016 DSTAVALNREEDFK--EIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB5 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN 540 550 560 570 580 590 610 620 630 640 650 pF1KB5 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS 600 610 620 630 640 650 >>XP_005263413 (OMIM: 138900,603756,614490) PREDICTED: A (653 aa) initn: 4226 init1: 2207 opt: 4226 Z-score: 4690.1 bits: 878.1 E(85289): 0 Smith-Waterman score: 4226; 99.7% identity (99.7% similar) in 655 aa overlap (1-655:1-653) 10 20 30 40 50 60 pF1KB5 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK :::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_005 DSTAVALNREEDFK--EIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 310 320 330 340 350 370 380 390 400 410 420 pF1KB5 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB5 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB5 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB5 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN 540 550 560 570 580 590 610 620 630 640 650 pF1KB5 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS 600 610 620 630 640 650 >>NP_001244315 (OMIM: 138900,603756,614490) ATP-binding (611 aa) initn: 3520 init1: 3520 opt: 3520 Z-score: 3907.4 bits: 733.2 E(85289): 6.6e-211 Smith-Waterman score: 3520; 99.8% identity (100.0% similar) in 550 aa overlap (1-550:1-550) 10 20 30 40 50 60 pF1KB5 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN :::::::::. NP_001 MTICFVFMMVCWSISQPLHLGCHGFSTSAFHDMDLRLCSIMNFWDKTSAQDSMQQETILV 550 560 570 580 590 600 >>NP_004906 (OMIM: 603076) ATP-binding cassette sub-fami (678 aa) initn: 740 init1: 369 opt: 945 Z-score: 1050.5 bits: 204.7 E(85289): 8.9e-52 Smith-Waterman score: 954; 29.2% identity (66.8% similar) in 602 aa overlap (56-650:93-672) 30 40 50 60 70 80 pF1KB5 NDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPG-LNAILGPTGG :: : .:..:.: .. : : ::.::.:. NP_004 AQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGA 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB5 GKSSLLDVLAARKDPSGLSGDVLINGAPRPAN-FKCNSGYVVQDDVVMGTLTVRENLQFS :::.:...::. .. .:..: ::::: :: :. : :..:::... :::.: .. : NP_004 GKSTLMNILAGYRE-TGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVS 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB5 AALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITD : :.: .. . : ..... ::: . :....:. .:::.::: .:..::... NP_004 AHLKLQEK--DEGRREMVKEILTALGLLSCANTRTGS-----LSGGQRKRLAIALELVNN 190 200 210 220 230 210 220 230 240 250 260 pF1KB5 PSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGR : ..:.::::.::::.. :. :.: ... ::.:: .:::: ..:.:::.: .:..:. NP_004 PPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQ 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB5 LMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSK ...: . . . :... : .: .:.::::: ... .:. ... . .. .. . NP_004 CVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYG------DQNSRLVRAVREGM 300 310 320 330 340 330 340 350 360 370 380 pF1KB5 QDKPLIEKLA-EIYVNSSFYKETKAELHQLS--GGEKKKKITVFKEISYTTSFCHQLRWV :. . :. . :: .... . :..: . : .: . .. :...: :. . NP_004 CDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCIL 350 360 370 380 390 400 390 400 410 420 430 440 pF1KB5 SKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFS ::.: ... . . .: . .::.:: .:.:. :.. . . .: ::: :. NP_004 FKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFA 410 420 430 440 450 460 450 460 470 480 490 pF1KB5 SV-SAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGL .. .: : .: .:..:... .: ...:.:.: ..:. :.... . . :::.: . NP_004 ALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADV-PFQIMFPVAYCSIVYWMTS- 470 480 490 500 510 520 500 510 520 530 540 550 pF1KB5 KPKADAFFVMMFTL-MMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNL .:. . ::.. .: :.. :.:..: :.:... ..:::.. . . ...:::..:.. NP_004 QPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSF 530 540 550 560 570 580 560 570 580 590 600 610 pF1KB5 TTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQG :: ..:.:..:.: :::: .. . . : . :. .. :.. : .... NP_004 DTIPTYLQWMSYISYVRYGFEGVILSIY-GLDR-EDLHCDIDETCHFQKS---EAILRE- 590 600 610 620 630 640 620 630 640 650 pF1KB5 IDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS .:. :. . ..:. ... . :::. : . NP_004 LDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 650 660 670 >>XP_011528108 (OMIM: 603076) PREDICTED: ATP-binding cas (689 aa) initn: 740 init1: 369 opt: 945 Z-score: 1050.4 bits: 204.7 E(85289): 9.1e-52 Smith-Waterman score: 954; 29.2% identity (66.8% similar) in 602 aa overlap (56-650:104-683) 30 40 50 60 70 80 pF1KB5 NDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPG-LNAILGPTGG :: : .:..:.: .. : : ::.::.:. XP_011 AQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGA 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB5 GKSSLLDVLAARKDPSGLSGDVLINGAPRPAN-FKCNSGYVVQDDVVMGTLTVRENLQFS :::.:...::. .. .:..: ::::: :: :. : :..:::... :::.: .. : XP_011 GKSTLMNILAGYRE-TGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVS 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB5 AALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITD : :.: .. . : ..... ::: . :....:. .:::.::: .:..::... XP_011 AHLKLQEK--DEGRREMVKEILTALGLLSCANTRTGS-----LSGGQRKRLAIALELVNN 200 210 220 230 240 210 220 230 240 250 260 pF1KB5 PSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGR : ..:.::::.::::.. :. :.: ... ::.:: .:::: ..:.:::.: .:..:. XP_011 PPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQ 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB5 LMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSK ...: . . . :... : .: .:.::::: ... .:. ... . .. .. . XP_011 CVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYG------DQNSRLVRAVREGM 310 320 330 340 350 330 340 350 360 370 380 pF1KB5 QDKPLIEKLA-EIYVNSSFYKETKAELHQLS--GGEKKKKITVFKEISYTTSFCHQLRWV :. . :. . :: .... . :..: . : .: . .. :...: :. . XP_011 CDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCIL 360 370 380 390 400 410 390 400 410 420 430 440 pF1KB5 SKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFS ::.: ... . . .: . .::.:: .:.:. :.. . . .: ::: :. XP_011 FKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFA 420 430 440 450 460 470 450 460 470 480 490 pF1KB5 SV-SAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGL .. .: : .: .:..:... .: ...:.:.: ..:. :.... . . :::.: . XP_011 ALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADV-PFQIMFPVAYCSIVYWMTS- 480 490 500 510 520 530 500 510 520 530 540 550 pF1KB5 KPKADAFFVMMFTL-MMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNL .:. . ::.. .: :.. :.:..: :.:... ..:::.. . . ...:::..:.. XP_011 QPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSF 540 550 560 570 580 590 560 570 580 590 600 610 pF1KB5 TTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQG :: ..:.:..:.: :::: .. . . : . :. .. :.. : .... XP_011 DTIPTYLQWMSYISYVRYGFEGVILSIY-GLDR-EDLHCDIDETCHFQKS---EAILRE- 600 610 620 630 640 650 620 630 640 650 pF1KB5 IDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS .:. :. . ..:. ... . :::. : . XP_011 LDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER 660 670 680 655 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:50:51 2016 done: Thu Nov 3 15:50:53 2016 Total Scan time: 10.370 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]