FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5063, 775 aa 1>>>pF1KB5063 775 - 775 aa - 775 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0822+/-0.00103; mu= 15.4219+/- 0.062 mean_var=67.1713+/-13.587, 0's: 0 Z-trim(103.7): 24 B-trim: 248 in 1/50 Lambda= 0.156489 statistics sampled from 7505 (7517) to 7505 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.231), width: 16 Scan time: 3.910 The best scores are: opt bits E(32554) CCDS2788.1 QARS gene_id:5859|Hs108|chr3 ( 775) 5228 1189.8 0 CCDS63633.1 QARS gene_id:5859|Hs108|chr3 ( 764) 4706 1072.0 0 CCDS31027.1 EPRS gene_id:2058|Hs108|chr1 (1512) 863 204.4 1.1e-51 >>CCDS2788.1 QARS gene_id:5859|Hs108|chr3 (775 aa) initn: 5228 init1: 5228 opt: 5228 Z-score: 6372.1 bits: 1189.8 E(32554): 0 Smith-Waterman score: 5228; 100.0% identity (100.0% similar) in 775 aa overlap (1-775:1-775) 10 20 30 40 50 60 pF1KB5 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 730 740 750 760 770 >>CCDS63633.1 QARS gene_id:5859|Hs108|chr3 (764 aa) initn: 4706 init1: 4706 opt: 4706 Z-score: 5735.3 bits: 1072.0 E(32554): 0 Smith-Waterman score: 5123; 98.5% identity (98.6% similar) in 775 aa overlap (1-775:1-764) 10 20 30 40 50 60 pF1KB5 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE :::::::::::::::::. ::::::::::::::::::::::::::::::: CCDS63 SRLRDTRRLSFLVSYIAT-----------ALEYVRSHPLDPIDTVDFERECGVGVIVTPE 70 80 90 100 130 140 150 160 170 180 pF1KB5 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB5 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB5 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB5 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB5 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 650 660 670 680 690 700 730 740 750 760 770 pF1KB5 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 710 720 730 740 750 760 >>CCDS31027.1 EPRS gene_id:2058|Hs108|chr1 (1512 aa) initn: 725 init1: 443 opt: 863 Z-score: 1041.3 bits: 204.4 E(32554): 1.1e-51 Smith-Waterman score: 888; 34.5% identity (60.2% similar) in 527 aa overlap (245-752:176-681) 220 230 240 250 260 270 pF1KB5 DQTLSLMEQLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITG---GQVRTRFPPE :.:. . . . .:. : :.: .::::: CCDS31 HVKRWFGFLEAQQAFQSVGTKWDVSTTKARVAPEKKQDVGKFVELPGAEMGKVTVRFPPE 150 160 170 180 190 200 280 290 300 310 320 330 pF1KB5 PNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYK .: :::::::: .: : .: ..::::::::::. : .: . :: : : . CCDS31 ASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQ 210 220 230 240 250 260 340 350 360 370 380 pF1KB5 VTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGH--NTLPSPWRDRPMEESLLLFEA ::.::.:. .. .: .::..: ::: .:..:.. . . : : :.:..: ..: CCDS31 FTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEE 270 280 290 300 310 320 390 400 410 420 430 440 pF1KB5 MRKG-KFSEGEATLRMKLVM--EDGKM-DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLC :.:: .:... :: :. : ..: : ::. :: : :: :::.:. .:::::.. . CCDS31 MKKGSQFGQS-CCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIV 330 340 350 360 370 380 450 460 470 480 490 500 pF1KB5 DSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVAT :::: .::.: : :.. : ...:. .:: . : :::.::::. .:.::::. .: CCDS31 DSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNE 390 400 410 420 430 440 510 520 530 540 550 560 pF1KB5 GAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTA : : :::::. :. .. :::. :....: : : . . ..:: . : . :.. .: CCDS31 GLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVA 450 460 470 480 490 500 570 580 590 600 610 620 pF1KB5 PRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTD---FKEE :: .:.:.. .:: .: : :. .: . : . :.. : ..: :::: .: :.: CCDS31 PRYVALLKK-EVIPVNVPEAQEEMKEVAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEG 510 520 530 540 550 560 630 640 650 660 670 680 pF1KB5 PEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVS : . ::. ... .. :. .: . ::.. . : . . :.. CCDS31 EMVTF--INWGN----------LNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWLA 570 580 590 600 610 690 700 710 720 730 pF1KB5 Q-------PLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALA . :..: . ::.:. : : : . .: : : . : : . CCDS31 ETTHALPIPVICVT--YEHLIT-KPVLGKDE---DFKQYVNKNSKHE-ELMLGDPCLKDL 620 630 640 650 660 740 750 760 770 pF1KB5 KPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV : : .:..: :.: : CCDS31 KKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVEAT 670 680 690 700 710 720 775 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:15:01 2016 done: Thu Nov 3 22:15:02 2016 Total Scan time: 3.910 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]