FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5063, 775 aa 1>>>pF1KB5063 775 - 775 aa - 775 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8903+/-0.000415; mu= 16.5941+/- 0.026 mean_var=71.5305+/-14.167, 0's: 0 Z-trim(110.5): 38 B-trim: 0 in 0/55 Lambda= 0.151645 statistics sampled from 18792 (18823) to 18792 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.584), E-opt: 0.2 (0.221), width: 16 Scan time: 10.290 The best scores are: opt bits E(85289) NP_005042 (OMIM: 603727,615760) glutamine--tRNA li ( 775) 5228 1153.8 0 XP_016862454 (OMIM: 603727,615760) PREDICTED: glut ( 751) 4843 1069.5 0 NP_001259002 (OMIM: 603727,615760) glutamine--tRNA ( 764) 4706 1039.6 0 NP_004437 (OMIM: 138295) bifunctional glutamate/pr (1512) 863 198.9 1.3e-49 NP_001077083 (OMIM: 612799,614924) probable glutam ( 523) 161 45.2 0.00087 NP_001295140 (OMIM: 612799,614924) probable glutam ( 534) 161 45.2 0.00089 >>NP_005042 (OMIM: 603727,615760) glutamine--tRNA ligase (775 aa) initn: 5228 init1: 5228 opt: 5228 Z-score: 6177.3 bits: 1153.8 E(85289): 0 Smith-Waterman score: 5228; 100.0% identity (100.0% similar) in 775 aa overlap (1-775:1-775) 10 20 30 40 50 60 pF1KB5 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 670 680 690 700 710 720 730 740 750 760 770 pF1KB5 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 730 740 750 760 770 >>XP_016862454 (OMIM: 603727,615760) PREDICTED: glutamin (751 aa) initn: 4930 init1: 4843 opt: 4843 Z-score: 5722.3 bits: 1069.5 E(85289): 0 Smith-Waterman score: 4850; 94.6% identity (94.6% similar) in 775 aa overlap (1-775:19-751) 10 20 30 40 pF1KB5 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQ :::::::::::::::::::::::::::::::::::::::::: XP_016 MPTCRLGPKFLLVSGVSAMAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 TLGSTIDKATGILLYGLASRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLGSTIDKATGILLYGLASRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPI 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB5 DTVDFERECGVGVIVTPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTVDFERECGVGVIVTPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 KMIKNEVDMQVLHLLGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMIKNEVDMQVLHLLGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLME 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB5 QLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAK 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB5 AINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQL 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB5 YAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB5 RMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQA 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB5 RRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTAL 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB5 RRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNF 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB5 PAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTG 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB5 YVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPE 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB5 DPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVF ::::::::::::::: ::: XP_016 DPTEVPGGFLSDLNL------------------------------------------LVF 730 770 pF1KB5 NRTVTLKEDPGKV ::::::::::::: XP_016 NRTVTLKEDPGKV 740 750 >>NP_001259002 (OMIM: 603727,615760) glutamine--tRNA lig (764 aa) initn: 4706 init1: 4706 opt: 4706 Z-score: 5560.2 bits: 1039.6 E(85289): 0 Smith-Waterman score: 5123; 98.5% identity (98.6% similar) in 775 aa overlap (1-775:1-764) 10 20 30 40 50 60 pF1KB5 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE :::::::::::::::::. ::::::::::::::::::::::::::::::: NP_001 SRLRDTRRLSFLVSYIAT-----------ALEYVRSHPLDPIDTVDFERECGVGVIVTPE 70 80 90 100 130 140 150 160 170 180 pF1KB5 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB5 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB5 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB5 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB5 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB5 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB5 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB5 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB5 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB5 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 650 660 670 680 690 700 730 740 750 760 770 pF1KB5 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 710 720 730 740 750 760 >>NP_004437 (OMIM: 138295) bifunctional glutamate/prolin (1512 aa) initn: 725 init1: 443 opt: 863 Z-score: 1011.6 bits: 198.9 E(85289): 1.3e-49 Smith-Waterman score: 888; 34.5% identity (60.2% similar) in 527 aa overlap (245-752:176-681) 220 230 240 250 260 270 pF1KB5 DQTLSLMEQLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITG---GQVRTRFPPE :.:. . . . .:. : :.: .::::: NP_004 HVKRWFGFLEAQQAFQSVGTKWDVSTTKARVAPEKKQDVGKFVELPGAEMGKVTVRFPPE 150 160 170 180 190 200 280 290 300 310 320 330 pF1KB5 PNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYK .: :::::::: .: : .: ..::::::::::. : .: . :: : : . NP_004 ASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQ 210 220 230 240 250 260 340 350 360 370 380 pF1KB5 VTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGH--NTLPSPWRDRPMEESLLLFEA ::.::.:. .. .: .::..: ::: .:..:.. . . : : :.:..: ..: NP_004 FTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEE 270 280 290 300 310 320 390 400 410 420 430 440 pF1KB5 MRKG-KFSEGEATLRMKLVM--EDGKM-DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLC :.:: .:... :: :. : ..: : ::. :: : :: :::.:. .:::::.. . NP_004 MKKGSQFGQS-CCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIV 330 340 350 360 370 380 450 460 470 480 490 500 pF1KB5 DSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVAT :::: .::.: : :.. : ...:. .:: . : :::.::::. .:.::::. .: NP_004 DSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNE 390 400 410 420 430 440 510 520 530 540 550 560 pF1KB5 GAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTA : : :::::. :. .. :::. :....: : : . . ..:: . : . :.. .: NP_004 GLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVA 450 460 470 480 490 500 570 580 590 600 610 620 pF1KB5 PRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTD---FKEE :: .:.:.. .:: .: : :. .: . : . :.. : ..: :::: .: :.: NP_004 PRYVALLKK-EVIPVNVPEAQEEMKEVAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEG 510 520 530 540 550 560 630 640 650 660 670 680 pF1KB5 PEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVS : . ::. ... .. :. .: . ::.. . : . . :.. NP_004 EMVTF--INWGN----------LNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWLA 570 580 590 600 610 690 700 710 720 730 pF1KB5 Q-------PLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALA . :..: . ::.:. : : : . .: : : . : : . NP_004 ETTHALPIPVICVT--YEHLIT-KPVLGKDE---DFKQYVNKNSKHE-ELMLGDPCLKDL 620 630 640 650 660 740 750 760 770 pF1KB5 KPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV : : .:..: :.: : NP_004 KKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVEAT 670 680 690 700 710 720 >>NP_001077083 (OMIM: 612799,614924) probable glutamate- (523 aa) initn: 158 init1: 158 opt: 161 Z-score: 188.9 bits: 45.2 E(85289): 0.00087 Smith-Waterman score: 209; 28.1% identity (51.2% similar) in 242 aa overlap (261-479:34-269) 240 250 260 270 280 290 pF1KB5 FHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGY : ::.:: : :.:.::.: .. .:. . NP_001 LLRRLLQRERPSAASGRPVGRREANLGTDAGVAVRVRFAPSPTGFLHLGGLRTALYNYIF 10 20 30 40 50 60 300 310 320 330 340 pF1KB5 AKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGY----TPYKVTYASDYFD----QL :: .: .::..::. . : ::. : : .: . :. : . .: NP_001 AKKYQGSFILRLEDTDQTRVVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQRLEL 70 80 90 100 110 120 350 360 370 380 390 pF1KB5 YAWAVE-LIRRGLAYVCH---QR-----GEELKGHNTLPSPWRDRPMEESLLLFEAMRKG :: :.: :.. : :: : :: : :..:.: : : : . . :.. . NP_001 YAQATEALLKTGAAYPCFCSPQRLELLKKEALRNHQTPRYDNRCRNMSQEQV---AQKLA 130 140 150 160 170 180 400 410 420 430 440 pF1KB5 KFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCI----YPTYDYTHCLCDSIE : . .:.. :. . .: : .. :: . .::: . :. :. . NP_001 KDPKPAIRFRLEQVVP-AFQDLVYGWNRHEVASVEGDPVIMKSDGFPTY-HLACVVDD-H 190 200 210 220 230 450 460 470 480 490 500 pF1KB5 H--ITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGA : :.: : .:. . .... : .:: : NP_001 HMGISHVLRGSEWLVSTAKHLLLYQALGWQPPHFAHLPLLLNRDGSKLSKRQGDVFLEHF 240 250 260 270 280 290 510 520 530 540 550 560 pF1KB5 VRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPR NP_001 AADGFLPDSLLDIITNCGSGFAENQMGRTLPELITQFNLTQVTCHSALLDLEKLPEFNRL 300 310 320 330 340 350 >>NP_001295140 (OMIM: 612799,614924) probable glutamate- (534 aa) initn: 158 init1: 158 opt: 161 Z-score: 188.8 bits: 45.2 E(85289): 0.00089 Smith-Waterman score: 209; 28.1% identity (51.2% similar) in 242 aa overlap (261-479:34-269) 240 250 260 270 280 290 pF1KB5 FHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGY : ::.:: : :.:.::.: .. .:. . NP_001 LLRRLLQRERPSAASGRPVGRREANLGTDAGVAVRVRFAPSPTGFLHLGGLRTALYNYIF 10 20 30 40 50 60 300 310 320 330 340 pF1KB5 AKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGY----TPYKVTYASDYFD----QL :: .: .::..::. . : ::. : : .: . :. : . .: NP_001 AKKYQGSFILRLEDTDQTRVVPGAAENIEDMLEWAGIPPDESPRRGGPAGPYQQSQRLEL 70 80 90 100 110 120 350 360 370 380 390 pF1KB5 YAWAVE-LIRRGLAYVCH---QR-----GEELKGHNTLPSPWRDRPMEESLLLFEAMRKG :: :.: :.. : :: : :: : :..:.: : : : . . :.. . NP_001 YAQATEALLKTGAAYPCFCSPQRLELLKKEALRNHQTPRYDNRCRNMSQEQV---AQKLA 130 140 150 160 170 180 400 410 420 430 440 pF1KB5 KFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCI----YPTYDYTHCLCDSIE : . .:.. :. . .: : .. :: . .::: . :. :. . NP_001 KDPKPAIRFRLEQVVP-AFQDLVYGWNRHEVASVEGDPVIMKSDGFPTY-HLACVVDD-H 190 200 210 220 230 450 460 470 480 490 500 pF1KB5 H--ITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGA : :.: : .:. . .... : .:: : NP_001 HMGISHVLRGSEWLVSTAKHLLLYQALGWQPPHFAHLPLLLNRDGSKLSKRQGDVFLEHF 240 250 260 270 280 290 510 520 530 540 550 560 pF1KB5 VRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPR NP_001 AADGFLPDSLLDIITNCGSGFAENQMGRTLPELITQFNLTQVTCHSALLDLEKLPEFNRL 300 310 320 330 340 350 775 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:15:02 2016 done: Thu Nov 3 22:15:03 2016 Total Scan time: 10.290 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]