Result of FASTA (omim) for
pF1KB5083
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5083, 685 aa
1>>>pF1KB5083 685 - 685 aa - 685 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0381+/-0.000534; mu= -1.4817+/- 0.033
mean_var=498.9657+/-111.689, 0's: 0 Z-trim(119.1): 1983 B-trim: 0 in 0/54
Lambda= 0.057417
statistics sampled from 30124 (32835) to 30124 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.385), width: 16
Scan time: 9.130
The best scores are: opt bits E(85289)
NP_006613 (OMIM: 607023) serine/threonine-protein ( 685) 4657 401.5 5.5e-111
NP_001239155 (OMIM: 607023) serine/threonine-prote ( 671) 4193 363.1 2e-99
NP_004064 (OMIM: 602913) serine/threonine-protein ( 646) 1499 139.9 2.9e-32
NP_005021 (OMIM: 602098) serine/threonine-protein ( 603) 1125 108.9 6e-23
XP_005262758 (OMIM: 605031,616171) PREDICTED: seri ( 936) 731 76.5 5.2e-13
XP_016863152 (OMIM: 605031,616171) PREDICTED: seri ( 937) 731 76.5 5.2e-13
NP_055079 (OMIM: 605031,616171) serine/threonine-p ( 970) 731 76.5 5.3e-13
XP_016863151 (OMIM: 605031,616171) PREDICTED: seri ( 971) 731 76.5 5.3e-13
NP_001177730 (OMIM: 605031,616171) serine/threonin ( 929) 676 71.9 1.2e-11
NP_001177728 (OMIM: 605031,616171) serine/threonin ( 938) 629 68.0 1.8e-10
NP_004208 (OMIM: 604970) aurora kinase B isoform 1 ( 344) 561 61.8 5e-09
NP_001300879 (OMIM: 604970) aurora kinase B isofor ( 344) 561 61.8 5e-09
NP_055655 (OMIM: 608130) NUAK family SNF1-like kin ( 661) 567 62.7 5.2e-09
NP_001271455 (OMIM: 604970) aurora kinase B isofor ( 345) 559 61.6 5.7e-09
XP_011522374 (OMIM: 604970) PREDICTED: aurora kina ( 303) 549 60.7 9.3e-09
XP_016880796 (OMIM: 604970) PREDICTED: aurora kina ( 303) 549 60.7 9.3e-09
NP_001243763 (OMIM: 604970) aurora kinase B isofor ( 303) 549 60.7 9.3e-09
NP_001300880 (OMIM: 604970) aurora kinase B isofor ( 303) 549 60.7 9.3e-09
NP_001300881 (OMIM: 604970) aurora kinase B isofor ( 304) 547 60.6 1e-08
XP_016883524 (OMIM: 603072) PREDICTED: aurora kina ( 403) 542 60.3 1.6e-08
NP_003591 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 542 60.3 1.6e-08
NP_940838 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 542 60.3 1.6e-08
NP_001310233 (OMIM: 603072) aurora kinase A [Homo ( 403) 542 60.3 1.6e-08
NP_001310234 (OMIM: 603072) aurora kinase A [Homo ( 403) 542 60.3 1.6e-08
NP_940835 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 542 60.3 1.6e-08
NP_940837 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 542 60.3 1.6e-08
NP_940839 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 542 60.3 1.6e-08
NP_001310232 (OMIM: 603072) aurora kinase A [Homo ( 403) 542 60.3 1.6e-08
NP_940836 (OMIM: 603072) aurora kinase A [Homo sap ( 403) 542 60.3 1.6e-08
XP_016883523 (OMIM: 603072) PREDICTED: aurora kina ( 437) 542 60.4 1.7e-08
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 537 60.3 3.2e-08
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 537 60.3 3.2e-08
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 536 60.2 3.2e-08
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 537 60.3 3.2e-08
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 537 60.3 3.2e-08
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 536 60.2 3.2e-08
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 536 60.2 3.3e-08
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660) 533 59.9 3.7e-08
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 532 59.8 4.1e-08
NP_001015878 (OMIM: 243060,603495) aurora kinase C ( 309) 523 58.6 4.2e-08
NP_001015879 (OMIM: 243060,603495) aurora kinase C ( 290) 522 58.5 4.3e-08
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 532 59.9 4.3e-08
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 531 59.8 4.3e-08
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 531 59.8 4.4e-08
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 531 59.8 4.4e-08
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 531 59.8 4.4e-08
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 531 59.8 4.4e-08
NP_115806 (OMIM: 609235) serine/threonine-protein ( 778) 531 59.8 4.5e-08
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 531 59.8 4.6e-08
XP_016872913 (OMIM: 614776) PREDICTED: serine/thre (1213) 533 60.2 5.2e-08
>>NP_006613 (OMIM: 607023) serine/threonine-protein kina (685 aa)
initn: 4657 init1: 4657 opt: 4657 Z-score: 2113.6 bits: 401.5 E(85289): 5.5e-111
Smith-Waterman score: 4657; 100.0% identity (100.0% similar) in 685 aa overlap (1-685:1-685)
10 20 30 40 50 60
pF1KB5 MELLRTITYQPAASTKMCEQALGKGCGADSKKKRPPQPPEESQPPQSQAQVPPAAPHHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MELLRTITYQPAASTKMCEQALGKGCGADSKKKRPPQPPEESQPPQSQAQVPPAAPHHHH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 HHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 CGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEEL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QPPTTTVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QPPTTTVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 GCLENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GCLENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 KKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 YLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTL
610 620 630 640 650 660
670 680
pF1KB5 LMSGCSSELKNRMEYALNMLLQRCN
:::::::::::::::::::::::::
NP_006 LMSGCSSELKNRMEYALNMLLQRCN
670 680
>>NP_001239155 (OMIM: 607023) serine/threonine-protein k (671 aa)
initn: 4183 init1: 4183 opt: 4193 Z-score: 1906.0 bits: 363.1 E(85289): 2e-99
Smith-Waterman score: 4500; 98.0% identity (98.0% similar) in 685 aa overlap (1-685:1-671)
10 20 30 40 50 60
pF1KB5 MELLRTITYQPAASTKMCEQALGKGCGADSKKKRPPQPPEESQPPQSQAQVPPAAPHHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELLRTITYQPAASTKMCEQALGKGCGADSKKKRPPQPPEESQPPQSQAQVPPA------
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 HHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAK
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------ISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAK
60 70 80 90 100
130 140 150 160 170 180
pF1KB5 PHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 EVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 CGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 KNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEEL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB5 QPPTTTVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPPTTTVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLR
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB5 GCLENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCLENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPD
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB5 KKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRL
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB5 YLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTL
590 600 610 620 630 640
670 680
pF1KB5 LMSGCSSELKNRMEYALNMLLQRCN
:::::::::::::::::::::::::
NP_001 LMSGCSSELKNRMEYALNMLLQRCN
650 660 670
>>NP_004064 (OMIM: 602913) serine/threonine-protein kina (646 aa)
initn: 2121 init1: 1464 opt: 1499 Z-score: 700.1 bits: 139.9 E(85289): 2.9e-32
Smith-Waterman score: 2126; 50.6% identity (74.9% similar) in 650 aa overlap (36-683:20-643)
10 20 30 40 50 60
pF1KB5 TITYQPAASTKMCEQALGKGCGADSKKKRPPQPPEESQPPQSQAQVPPAAPHHHHHHSHS
: :: :: : . : :
NP_004 MEPAAGFLSPRPFQRAAAAPAPPAGPGPPPSALRGPELEMLAGLPTSDP
10 20 30 40
70 80 90 100 110 120
pF1KB5 GPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQRE
: :.:.:: .:. : .:..:::::::.::: :: ....::.:.::.::::::::::
NP_004 G----RLITDPRSGRTYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQRE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB5 KIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYY
:: .:::::: :.:.:.:.: :.::: .::::.:: :::.:.::: :::..: :::::::
NP_004 KILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB5 LRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPN
::::.:::::::.. :::::::::::::.: :::::::::::::::: :.:..:::::::
NP_004 LRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPN
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB5 YLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLA
:..:::: .:::: :.:.:.:::::::.: : :::::..::::::::....::.:.::
NP_004 YVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 PAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKNFFK
::..:.:..: .:.::::.:.:.::::: .:.::::: : : ::::. .::...:
NP_004 PARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVPDLTPPNPARSLFA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 KAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEELQPPTT
:.. .::: :: ..:.....:: . : : .::. .: .. .. : .
NP_004 KVTKSLFGRKKK------SKNHAQERDE-VSGLVSGLMRTSVGHQDARPEAPAASGPAPV
350 360 370 380 390
430 440 450 460 470 480
pF1KB5 TVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLRGCLEN
..... : :... ::::.: ... : : :...:.... .::.:.
NP_004 SLVET---APEDSSP---------RGTLASSGDGFE--EGLTVATVVESALCALRNCIAF
400 410 420 430 440
490 500 510 520 530 540
pF1KB5 MPEADCIPKEQLSTS-FQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTV
:: :. : . . ::.::::::::.:::::::.. :.::::.:.::.: ..:::
NP_004 MPPAEQNPAPLAQPEPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTV
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB5 HYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRL-YLL
:: . : . .:. . :. .:.::. :::..:: ::::::: ... : ::
NP_004 HYNPTSTKHFSFSVGAVPRALQPQLGILRYFASYMEQHLMKGGDLPSVEEVEVPAPPLLL
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB5 QWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTLLMS
::.:.:.::.:::.::: ::::: ::::.:. : : :.:.. ..: . :. . : .
NP_004 QWVKTDQALLMLFSDGTVQVNFYGDHTKLIL-SGWEPLLVTFVARNRSACTYLASHLRQL
570 580 590 600 610 620
670 680
pF1KB5 GCSSELKNRMEYALNMLLQRCN
::: .:..:..::: .: .:
NP_004 GCSPDLRQRLRYALRLLRDRSPA
630 640
>>NP_005021 (OMIM: 602098) serine/threonine-protein kina (603 aa)
initn: 1511 init1: 1099 opt: 1125 Z-score: 533.0 bits: 108.9 E(85289): 6e-23
Smith-Waterman score: 1514; 38.5% identity (65.6% similar) in 652 aa overlap (33-680:12-587)
10 20 30 40 50 60
pF1KB5 LLRTITYQPAASTKMCEQALGKGCGADSKKKRPPQPPEESQPPQSQAQVPPAAPHHHHHH
. : .: . . : . .: :::
NP_005 MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAP------
10 20 30
70 80 90 100 110 120
pF1KB5 SHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPH
. :: ...::: . .:: ::. :::::::::.:..: ...:.:.::.:.: . :::
NP_005 --PAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPH
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 QREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEV
::::.. :: .:: : :.::: :. .:::.. ....:: : :::. .. : ::.:::::.
NP_005 QREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEA
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 RYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICG
:::::::: : .:::.....::::::::.:.:: .:.:.::::::...: .:..:.::
NP_005 RYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 TPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSS
::::..::::.:.::. : :.:..::.:::.:.:.:::::. ::::: :.. .:..:.
NP_005 TPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKH
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 LLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKN
. : :: .::. .: ::...... .:: .:. : :: .: : : .. :..
NP_005 INPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIA-PSS-
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 FFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEELQP
.: :: . . : . : ..: .: :. .:
NP_005 -------------------LDPSNR-----KPLTVLNKGL------ENPLPERPREKEEP
340 350 360
430 440 450 460 470 480
pF1KB5 PTTTVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLRGC
:.: .:. ...: ... : : ..: . : : : .
NP_005 ----VVRETGEVVDC--HLSDMLQQ-----LHSVNAS----KPSERGLVRQ---------
370 380 390
490 500 510 520 530 540
pF1KB5 LENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKK
:. . ::: . ::.::::::.:::.:::: :..::::::..... : :
NP_005 -EEAEDPACIP-------IFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGD
400 410 420 430 440
550 560 570 580 590
pF1KB5 TVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGD--LPSVTD--IRRP
...: . : : . ... :.......:.:::: .:: :.:. .: : : : :
NP_005 SLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLP
450 460 470 480 490 500
600 610 620 630 640 650
pF1KB5 RLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLT
:: :... .:... ...:. :.::..::::.:.: .:::.: : :.::.
NP_005 --YLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAA--VTYIDEKRDFRTYRLS
510 520 530 540 550 560
660 670 680
pF1KB5 TLLMSGCSSELKNRMEYALNMLLQRCN
: :: .:: .:..:: .:.
NP_005 LLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS
570 580 590 600
>>XP_005262758 (OMIM: 605031,616171) PREDICTED: serine/t (936 aa)
initn: 751 init1: 547 opt: 731 Z-score: 354.6 bits: 76.5 E(85289): 5.2e-13
Smith-Waterman score: 731; 41.6% identity (76.4% similar) in 250 aa overlap (85-333:15-264)
60 70 80 90 100 110
pF1KB5 APHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIP
:..::::.:: :. .. .. : :.:
XP_005 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID
10 20 30 40
120 130 140 150 160 170
pF1KB5 HSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR
.. . : . .....:...: :.: ....:.::::.. .:..::.: : . :: :
XP_005 KKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNR
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB5 -KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL
: ..: :.:....::..:. ::: . :::::: :.:..... :..:..:::::..:.
XP_005 VKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP
110 120 130 140 150 160
240 250 260 270 280 290
pF1KB5 EHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIR
.... :.::::::.:::. ....:: :::.:.:::..::.:.:::::.: ..:.: .
XP_005 HEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPD
: : ::: : :: :: ..: .:: :: ::.... : :
XP_005 LADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 FHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSK
XP_005 SGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFY
290 300 310 320 330 340
>>XP_016863152 (OMIM: 605031,616171) PREDICTED: serine/t (937 aa)
initn: 751 init1: 547 opt: 731 Z-score: 354.6 bits: 76.5 E(85289): 5.2e-13
Smith-Waterman score: 731; 41.6% identity (76.4% similar) in 250 aa overlap (85-333:16-265)
60 70 80 90 100 110
pF1KB5 APHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIP
:..::::.:: :. .. .. : :.:
XP_016 MPSTLDTCCIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID
10 20 30 40
120 130 140 150 160 170
pF1KB5 HSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR
.. . : . .....:...: :.: ....:.::::.. .:..::.: : . :: :
XP_016 KKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNR
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB5 -KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL
: ..: :.:....::..:. ::: . :::::: :.:..... :..:..:::::..:.
XP_016 VKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP
110 120 130 140 150 160
240 250 260 270 280 290
pF1KB5 EHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIR
.... :.::::::.:::. ....:: :::.:.:::..::.:.:::::.: ..:.: .
XP_016 HEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPD
: : ::: : :: :: ..: .:: :: ::.... : :
XP_016 LADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 FHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSK
XP_016 SGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFY
290 300 310 320 330 340
>>NP_055079 (OMIM: 605031,616171) serine/threonine-prote (970 aa)
initn: 751 init1: 547 opt: 731 Z-score: 354.5 bits: 76.5 E(85289): 5.3e-13
Smith-Waterman score: 731; 41.6% identity (76.4% similar) in 250 aa overlap (85-333:15-264)
60 70 80 90 100 110
pF1KB5 APHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIP
:..::::.:: :. .. .. : :.:
NP_055 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID
10 20 30 40
120 130 140 150 160 170
pF1KB5 HSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR
.. . : . .....:...: :.: ....:.::::.. .:..::.: : . :: :
NP_055 KKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNR
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB5 -KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL
: ..: :.:....::..:. ::: . :::::: :.:..... :..:..:::::..:.
NP_055 VKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP
110 120 130 140 150 160
240 250 260 270 280 290
pF1KB5 EHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIR
.... :.::::::.:::. ....:: :::.:.:::..::.:.:::::.: ..:.: .
NP_055 HEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPD
: : ::: : :: :: ..: .:: :: ::.... : :
NP_055 LADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 FHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSK
NP_055 SGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFY
290 300 310 320 330 340
>>XP_016863151 (OMIM: 605031,616171) PREDICTED: serine/t (971 aa)
initn: 751 init1: 547 opt: 731 Z-score: 354.4 bits: 76.5 E(85289): 5.3e-13
Smith-Waterman score: 731; 41.6% identity (76.4% similar) in 250 aa overlap (85-333:16-265)
60 70 80 90 100 110
pF1KB5 APHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIP
:..::::.:: :. .. .. : :.:
XP_016 MPSTLDTCCIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMID
10 20 30 40
120 130 140 150 160 170
pF1KB5 HSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKAR
.. . : . .....:...: :.: ....:.::::.. .:..::.: : . :: :
XP_016 KKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNR
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB5 -KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPL
: ..: :.:....::..:. ::: . :::::: :.:..... :..:..:::::..:.
XP_016 VKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMP
110 120 130 140 150 160
240 250 260 270 280 290
pF1KB5 EHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIR
.... :.::::::.:::. ....:: :::.:.:::..::.:.:::::.: ..:.: .
XP_016 HEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVV
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPD
: : ::: : :: :: ..: .:: :: ::.... : :
XP_016 LADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 FHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSK
XP_016 SGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFY
290 300 310 320 330 340
>>NP_001177730 (OMIM: 605031,616171) serine/threonine-pr (929 aa)
initn: 647 init1: 547 opt: 676 Z-score: 330.0 bits: 71.9 E(85289): 1.2e-11
Smith-Waterman score: 676; 42.2% identity (77.6% similar) in 223 aa overlap (112-333:1-223)
90 100 110 120 130 140
pF1KB5 YCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKH
.: .. . : . .....:...: :.:
NP_001 MIDKKAMYKAGMVQRVQNEVKIHCQLKHPS
10 20 30
150 160 170 180 190 200
pF1KB5 VVQFYHYFEDKENIYILLEYCSRRSMAHILKAR-KVLTEPEVRYYLRQIVSGLKYLHEQE
....:.::::.. .:..::.: : . :: : : ..: :.:....::..:. ::: .
NP_001 ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB5 ILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCE
:::::: :.:..... :..:..:::::..:. .... :.::::::.:::. ....:: :
NP_001 ILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLE
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB5 SDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPE
::.:.:::..::.:.:::::.: ..:.: . : : ::: : :: :: ..: .::
NP_001 SDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPA
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB5 DRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKNFFKKAAAALFGGKKDKAR
:: ::.... : :
NP_001 DRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRR
220 230 240 250 260 270
>>NP_001177728 (OMIM: 605031,616171) serine/threonine-pr (938 aa)
initn: 678 init1: 547 opt: 629 Z-score: 308.9 bits: 68.0 E(85289): 1.8e-10
Smith-Waterman score: 629; 45.6% identity (78.8% similar) in 193 aa overlap (142-333:40-232)
120 130 140 150 160 170
pF1KB5 IIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHIL
. ..:.::::.. .:..::.: : . :
NP_001 EDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMLYNYFEDSNYVYLVLEMCHNGEMNRYL
10 20 30 40 50 60
180 190 200 210 220 230
pF1KB5 KAR-KVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARL
: : : ..: :.:....::..:. ::: . :::::: :.:..... :..:..:::::..:
NP_001 KNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQL
70 80 90 100 110 120
240 250 260 270 280 290
pF1KB5 EPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYR
. .... :.::::::.:::. ....:: :::.:.:::..::.:.:::::.: ..:.:
NP_001 KMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLN
130 140 150 160 170 180
300 310 320 330 340 350
pF1KB5 CIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHT
. : : ::: : :: :: ..: .:: :: ::.... : :
NP_001 KVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVED
190 200 210 220 230 240
360 370 380 390 400 410
pF1KB5 VPDFHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQ
NP_001 SIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGN
250 260 270 280 290 300
685 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:15:43 2016 done: Thu Nov 3 22:15:44 2016
Total Scan time: 9.130 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]