FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5086, 660 aa 1>>>pF1KB5086 660 - 660 aa - 660 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4209+/-0.000368; mu= 11.9097+/- 0.023 mean_var=161.5250+/-32.923, 0's: 0 Z-trim(118.5): 18 B-trim: 0 in 0/56 Lambda= 0.100915 statistics sampled from 31437 (31455) to 31437 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.369), width: 16 Scan time: 12.130 The best scores are: opt bits E(85289) NP_004277 (OMIM: 602245) GTP-binding protein 1 [Ho ( 669) 4354 646.2 1.2e-184 XP_016884589 (OMIM: 602245) PREDICTED: GTP-binding ( 726) 4272 634.2 4.8e-181 XP_011528839 (OMIM: 602245) PREDICTED: GTP-binding ( 703) 4246 630.5 6.5e-180 XP_016884588 (OMIM: 602245) PREDICTED: GTP-binding ( 734) 4246 630.5 6.7e-180 XP_016884590 (OMIM: 602245) PREDICTED: GTP-binding ( 684) 3626 540.2 9.5e-153 XP_016884592 (OMIM: 602245) PREDICTED: GTP-binding ( 614) 3580 533.4 9.1e-151 XP_016884591 (OMIM: 602245) PREDICTED: GTP-binding ( 622) 3554 529.7 1.3e-149 NP_061969 (OMIM: 607434) GTP-binding protein 2 iso ( 602) 1688 258.0 7.4e-68 NP_001273145 (OMIM: 607434) GTP-binding protein 2 ( 514) 1639 250.8 9.3e-66 XP_016866465 (OMIM: 607434) PREDICTED: GTP-binding ( 493) 1352 209.0 3.4e-53 NP_001138630 (OMIM: 612450) HBS1-like protein isof ( 642) 300 55.9 5.3e-07 NP_006611 (OMIM: 612450) HBS1-like protein isoform ( 684) 300 55.9 5.5e-07 NP_001949 (OMIM: 602959,616393,616409) elongation ( 463) 250 48.5 6.4e-05 NP_003312 (OMIM: 602389,610678) elongation factor ( 455) 221 44.3 0.0012 XP_016879108 (OMIM: 602389,610678) PREDICTED: elon ( 455) 221 44.3 0.0012 >>NP_004277 (OMIM: 602245) GTP-binding protein 1 [Homo s (669 aa) initn: 4354 init1: 4354 opt: 4354 Z-score: 3436.3 bits: 646.2 E(85289): 1.2e-184 Smith-Waterman score: 4354; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:10-669) 10 20 30 40 50 pF1KB5 MDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 THGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 THGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 CEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 VPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMC 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 PIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 IKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB5 SPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATV 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB5 HFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB5 KRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQG 610 620 630 640 650 660 660 pF1KB5 ACVTPASGC ::::::::: NP_004 ACVTPASGC >>XP_016884589 (OMIM: 602245) PREDICTED: GTP-binding pro (726 aa) initn: 4272 init1: 4272 opt: 4272 Z-score: 3371.3 bits: 634.2 E(85289): 4.8e-181 Smith-Waterman score: 4272; 99.5% identity (99.7% similar) in 652 aa overlap (1-652:10-661) 10 20 30 40 50 pF1KB5 MDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB5 KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB5 THGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB5 CEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB5 VPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMC 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB5 PIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB5 IKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB5 SPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATV 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB5 HFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB5 KRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQG ::::::::::::::::::::::::::::::::::::::::::::::::::::::: . :: XP_016 KRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKSQVQG 610 620 630 640 650 660 660 pF1KB5 ACVTPASGC : XP_016 ANSEFPWRRITALQVDVAGRVTSASLFPQPPPTAPQRTNQKGDYLNKSCKSPRGQPERTT 670 680 690 700 710 720 >>XP_011528839 (OMIM: 602245) PREDICTED: GTP-binding pro (703 aa) initn: 3275 init1: 3275 opt: 4246 Z-score: 3351.0 bits: 630.5 E(85289): 6.5e-180 Smith-Waterman score: 4246; 98.3% identity (98.5% similar) in 660 aa overlap (1-652:10-669) 10 20 30 40 50 pF1KB5 MDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV 70 80 90 100 110 120 120 130 140 150 160 pF1KB5 KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVR--------VAVVGNVDAG :::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_011 KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRCMGSSTRRVAVVGNVDAG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 KSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB5 GSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEH 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB5 LGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTAS 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB5 NFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVV 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB5 SGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSS 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB5 IRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCL 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB5 RTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQ 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB5 STKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQ 610 620 630 640 650 660 650 660 pF1KB5 RHKVKSQGACVTPASGC ::: . ::: XP_011 RHKSQVQGANSEFPWRRITALQVDVAGRKLPSCCPSGRCLPLC 670 680 690 700 >>XP_016884588 (OMIM: 602245) PREDICTED: GTP-binding pro (734 aa) initn: 3275 init1: 3275 opt: 4246 Z-score: 3350.8 bits: 630.5 E(85289): 6.7e-180 Smith-Waterman score: 4246; 98.3% identity (98.5% similar) in 660 aa overlap (1-652:10-669) 10 20 30 40 50 pF1KB5 MDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV 70 80 90 100 110 120 120 130 140 150 160 pF1KB5 KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVR--------VAVVGNVDAG :::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRCMGSSTRRVAVVGNVDAG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB5 KSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB5 GSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEH 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB5 LGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTAS 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB5 NFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVV 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB5 SGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSS 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB5 IRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCL 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB5 RTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQ 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB5 STKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQ 610 620 630 640 650 660 650 660 pF1KB5 RHKVKSQGACVTPASGC ::: . ::: XP_016 RHKSQVQGANSEFPWRRITALQVDVAGRVTSASLFPQPPPTAPQRTNQKGDYLNKSCKSP 670 680 690 700 710 720 >>XP_016884590 (OMIM: 602245) PREDICTED: GTP-binding pro (684 aa) initn: 3275 init1: 3275 opt: 3626 Z-score: 2863.3 bits: 540.2 E(85289): 9.5e-153 Smith-Waterman score: 3626; 98.1% identity (98.2% similar) in 568 aa overlap (93-652:52-619) 70 80 90 100 110 120 pF1KB5 SEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADV :::::::::::::::::::::::::::::: XP_016 SLGRDQEAQVGLDASLKKHFSLLNVGFVKPDGTEYGLSEADMEASYATVKSMAEQIEADV 30 40 50 60 70 80 130 140 150 160 170 pF1KB5 ILLRERQEAGGRVRDYLVRKRVGDNDFLEVR--------VAVVGNVDAGKSTLLGVLTHG ::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_016 ILLRERQEAGGRVRDYLVRKRVGDNDFLEVRCMGSSTRRVAVVGNVDAGKSTLLGVLTHG 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB5 ELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEK 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB5 STKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPV 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB5 FVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIF 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB5 QISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKL 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB5 NDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPR 390 400 410 420 430 440 480 490 500 510 520 530 pF1KB5 LNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFR 450 460 470 480 490 500 540 550 560 570 580 590 pF1KB5 FIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRD 510 520 530 540 550 560 600 610 620 630 640 650 pF1KB5 EGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQGACV :::::::::::::::::::::::::::::::::::::::::::::::::::: . ::: XP_016 EGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKSQVQGANS 570 580 590 600 610 620 660 pF1KB5 TPASGC XP_016 EFPWRRITALQVDVAGRVTSASLFPQPPPTAPQRTNQKGDYLNKSCKSPRGQPERTTPTS 630 640 650 660 670 680 >>XP_016884592 (OMIM: 602245) PREDICTED: GTP-binding pro (614 aa) initn: 3580 init1: 3580 opt: 3580 Z-score: 2827.8 bits: 533.4 E(85289): 9.1e-151 Smith-Waterman score: 3580; 99.5% identity (99.6% similar) in 549 aa overlap (104-652:1-549) 80 90 100 110 120 130 pF1KB5 WERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADVILLRERQEAGG :::::::::::::::::::::::::::::: XP_016 MEASYATVKSMAEQIEADVILLRERQEAGG 10 20 30 140 150 160 170 180 190 pF1KB5 RVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHE 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB5 IESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKT 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB5 TVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETL 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB5 KLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNL 220 230 240 250 260 270 380 390 400 410 420 430 pF1KB5 LSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAV 280 290 300 310 320 330 440 450 460 470 480 490 pF1KB5 KSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHP 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB5 TTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREG 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB5 RTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEA 460 470 480 490 500 510 620 630 640 650 660 pF1KB5 SSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQGACVTPASGC ::::::::::::::::::::::::::::::::: . ::: XP_016 SSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKSQVQGANSEFPWRRITALQVDVAGRVT 520 530 540 550 560 570 XP_016 SASLFPQPPPTAPQRTNQKGDYLNKSCKSPRGQPERTTPTSGPG 580 590 600 610 >>XP_016884591 (OMIM: 602245) PREDICTED: GTP-binding pro (622 aa) initn: 3275 init1: 3275 opt: 3554 Z-score: 2807.2 bits: 529.7 E(85289): 1.3e-149 Smith-Waterman score: 3554; 98.0% identity (98.2% similar) in 557 aa overlap (104-652:1-557) 80 90 100 110 120 130 pF1KB5 WERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADVILLRERQEAGG :::::::::::::::::::::::::::::: XP_016 MEASYATVKSMAEQIEADVILLRERQEAGG 10 20 30 140 150 160 170 180 pF1KB5 RVRDYLVRKRVGDNDFLEVR--------VAVVGNVDAGKSTLLGVLTHGELDNGRGFARQ :::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_016 RVRDYLVRKRVGDNDFLEVRCMGSSTRRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQ 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB5 KLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLA 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB5 GHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCP 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB5 ANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLD 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB5 LLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPL 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB5 GNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEA 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB5 EILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHID 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB5 QRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVG 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB5 APPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQGACVTPASGC ::::::::::::::::::::::::::::::::::::::::: . ::: XP_016 APPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKSQVQGANSEFPWRRITALQ 520 530 540 550 560 570 XP_016 VDVAGRVTSASLFPQPPPTAPQRTNQKGDYLNKSCKSPRGQPERTTPTSGPG 580 590 600 610 620 >>NP_061969 (OMIM: 607434) GTP-binding protein 2 isoform (602 aa) initn: 1708 init1: 483 opt: 1688 Z-score: 1339.2 bits: 258.0 E(85289): 7.4e-68 Smith-Waterman score: 1692; 47.5% identity (74.2% similar) in 598 aa overlap (1-568:1-592) 10 20 30 40 pF1KB5 MDSPVPASMFAPEPSSPGAARAAAAAARLHG-GFDSDCS-EDGEALNGE----------- ::: : . .:. ::.. :.... . .: : .: :. :. ::. NP_061 MDSRV-SELFGGC-CRPGGGPAVGGTLKARGAGSSSGCGGPKGKKKNGRNRGGKANNPPY 10 20 30 40 50 50 60 70 80 90 100 pF1KB5 --PELD---LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEA :: . . :: ::.:.. ... :. :: :..:: ::..: :: ..: ::.: NP_061 LPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEE 60 70 80 90 100 110 110 120 130 140 150 pF1KB5 DMEASYATVKSMAEQIEADVILLRERQ-----EAGGRVRDYLVRKRVGDNDFLEVRVAVV .:.:: :.. :::.. ::. .::::. . .. . :::: ...::..::::. NP_061 EMRASLKTLHRMAEKVGADITVLREREVDYDSDMPRKITEVLVRKVPDNQQFLDLRVAVL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB5 GNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVN ::::.::::::::::.:::::::: :: .:::: :::.::::::.. .::::.:.:.::: NP_061 GNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVN 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 KPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIV ::. . .:::.:.:.:::::::::.:::.::.::.:.. :: .:.:..:.::. NP_061 YSDSRTAE----EICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIA 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB5 GMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDD : :.:::::::::.:: :.::.:::.: . ...:.. :.:.::.:::.:.:.:: :.:: NP_061 GTTREHLGLALALKVPFFIVVSKIDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDD 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB5 VIVTASNFS-SERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEP-----AEFQID ....:..:. : . ::: .:.:.::.:::::.:::.: : :. .:.: .:::.: NP_061 AVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVD 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB5 DTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQT . :.:: :::::.:: :. . .: :..:: : :: . : ::.:.: . .:.::. NP_061 EIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQA 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB5 ASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQ :..:: . :. .:::::::::..:: :::::..: : ::. .:. :: :..:: NP_061 ATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQ 480 490 500 510 520 530 520 530 540 550 560 570 pF1KB5 TATILSMD-KDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNN ::.. .. :: ::::.::.:.:::.: ::::.. .:.:::: ::..: .: . : NP_061 TAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVTDVQAITAG 540 550 560 570 580 590 580 590 600 610 620 630 pF1KB5 SPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQ NP_061 EAQANMGF 600 >>NP_001273145 (OMIM: 607434) GTP-binding protein 2 isof (514 aa) initn: 1649 init1: 483 opt: 1639 Z-score: 1301.6 bits: 250.8 E(85289): 9.3e-66 Smith-Waterman score: 1639; 51.3% identity (78.1% similar) in 507 aa overlap (74-568:3-504) 50 60 70 80 90 100 pF1KB5 LNGEPELDLTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEAD : :..:: ::..: :: ..: ::.: . NP_001 MKW-RLQEGRGEAVYQIGVEDNGLLVGLAEEE 10 20 30 110 120 130 140 150 pF1KB5 MEASYATVKSMAEQIEADVILLRERQ-----EAGGRVRDYLVRKRVGDNDFLEVRVAVVG :.:: :.. :::.. ::. .::::. . .. . :::: ...::..::::.: NP_001 MRASLKTLHRMAEKVGADITVLREREVDYDSDMPRKITEVLVRKVPDNQQFLDLRVAVLG 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB5 NVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNK :::.::::::::::.:::::::: :: .:::: :::.::::::.. .::::.:.:.::: NP_001 NVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNY 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB5 PDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVG ::. . .:::.:.:.:::::::::.:::.::.::.:.. :: .:.:..:.::.: NP_001 SDSRTAE----EICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAG 160 170 180 190 200 280 290 300 310 320 330 pF1KB5 MTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDV :.:::::::::.:: :.::.:::.: . ...:.. :.:.::.:::.:.:.:: :.::. NP_001 TTREHLGLALALKVPFFIVVSKIDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDDA 210 220 230 240 250 260 340 350 360 370 380 390 pF1KB5 IVTASNFS-SERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEP-----AEFQIDD ...:..:. : . ::: .:.:.::.:::::.:::.: : :. .:.: .:::.:. NP_001 VTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVDE 270 280 290 300 310 320 400 410 420 430 440 450 pF1KB5 TYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTA :.:: :::::.:: :. . .: :..:: : :: . : ::.:.: . .:.::.: NP_001 IYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQAA 330 340 350 360 370 380 460 470 480 490 500 510 pF1KB5 SFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQT ..:: . :. .:::::::::..:: :::::..: : ::. .:. :: :..::: NP_001 TLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQT 390 400 410 420 430 440 520 530 540 550 560 570 pF1KB5 ATILSMD-KDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNS :.. .. :: ::::.::.:.:::.: ::::.. .:.:::: ::..: .: . : NP_001 AVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVTDVQAITAGE 450 460 470 480 490 500 580 590 600 610 620 630 pF1KB5 PMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQP NP_001 AQANMGF 510 >>XP_016866465 (OMIM: 607434) PREDICTED: GTP-binding pro (493 aa) initn: 1246 init1: 483 opt: 1352 Z-score: 1076.0 bits: 209.0 E(85289): 3.4e-53 Smith-Waterman score: 1356; 46.7% identity (73.9% similar) in 495 aa overlap (1-466:1-489) 10 20 30 40 pF1KB5 MDSPVPASMFAPEPSSPGAARAAAAAARLHG-GFDSDCS-EDGEALNGE----------- ::: : . .:. ::.. :.... . .: : .: :. :. ::. XP_016 MDSRV-SELFGGC-CRPGGGPAVGGTLKARGAGSSSGCGGPKGKKKNGRNRGGKANNPPY 10 20 30 40 50 50 60 70 80 90 100 pF1KB5 --PELD---LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEA :: . . :: ::.:.. ... :. :: :..:: ::..: :: ..: ::.: XP_016 LPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEE 60 70 80 90 100 110 110 120 130 140 150 pF1KB5 DMEASYATVKSMAEQIEADVILLRERQ-----EAGGRVRDYLVRKRVGDNDFLEVRVAVV .:.:: :.. :::.. ::. .::::. . .. . :::: ...::..::::. XP_016 EMRASLKTLHRMAEKVGADITVLREREVDYDSDMPRKITEVLVRKVPDNQQFLDLRVAVL 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB5 GNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVN ::::.::::::::::.:::::::: :: .:::: :::.::::::.. .::::.:.:.::: XP_016 GNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVN 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB5 KPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIV ::. . .:::.:.:.:::::::::.:::.::.::.:.. :: .:.:..:.::. XP_016 YSDSRTAE----EICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIA 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB5 GMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDD : :.:::::::::.:: :.::.:::.: . ...:.. :.:.::.:::.:.:.:: :.:: XP_016 GTTREHLGLALALKVPFFIVVSKIDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDD 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB5 VIVTASNFS-SERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEP-----AEFQID ....:..:. : . ::: .:.:.::.:::::.:::.: : :. .:.: .:::.: XP_016 AVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVD 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB5 DTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQT . :.:: :::::.:: :. . .: :..:: : :: . : ::.:.: . .:.::. XP_016 EIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQA 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB5 ASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQ :..:: . :. .:: XP_016 ATLALGDFDRALLRKVRAW 480 490 660 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:55:39 2016 done: Thu Nov 3 15:55:40 2016 Total Scan time: 12.130 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]