FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5090, 769 aa 1>>>pF1KB5090 769 - 769 aa - 769 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1989+/-0.000528; mu= 5.5050+/- 0.032 mean_var=156.5381+/-32.550, 0's: 0 Z-trim(111.8): 97 B-trim: 504 in 1/54 Lambda= 0.102510 statistics sampled from 20399 (20493) to 20399 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.24), width: 16 Scan time: 11.700 The best scores are: opt bits E(85289) NP_003141 (OMIM: 102582,147060,615952) signal tran ( 769) 5134 772.5 0 XP_005257673 (OMIM: 102582,147060,615952) PREDICTE ( 769) 5134 772.5 0 XP_016880464 (OMIM: 102582,147060,615952) PREDICTE ( 769) 5134 772.5 0 XP_011523447 (OMIM: 102582,147060,615952) PREDICTE ( 770) 5122 770.7 0 XP_005257674 (OMIM: 102582,147060,615952) PREDICTE ( 770) 5122 770.7 0 NP_644805 (OMIM: 102582,147060,615952) signal tran ( 770) 5122 770.7 0 XP_016880462 (OMIM: 102582,147060,615952) PREDICTE ( 721) 4765 717.9 3.7e-206 XP_016880463 (OMIM: 102582,147060,615952) PREDICTE ( 721) 4765 717.9 3.7e-206 XP_016880465 (OMIM: 102582,147060,615952) PREDICTE ( 721) 4765 717.9 3.7e-206 XP_016880461 (OMIM: 102582,147060,615952) PREDICTE ( 722) 4753 716.1 1.3e-205 NP_998827 (OMIM: 102582,147060,615952) signal tran ( 722) 4753 716.1 1.3e-205 XP_011523448 (OMIM: 102582,147060,615952) PREDICTE ( 722) 4753 716.1 1.3e-205 XP_006712781 (OMIM: 600555,613796,614162,614892) P ( 750) 2643 404.1 1.1e-111 NP_009330 (OMIM: 600555,613796,614162,614892) sign ( 750) 2643 404.1 1.1e-111 XP_016860272 (OMIM: 600555,613796,614162,614892) P ( 752) 2643 404.1 1.1e-111 NP_644671 (OMIM: 600555,613796,614162,614892) sign ( 712) 2614 399.8 2.1e-110 NP_003142 (OMIM: 600558,612253) signal transducer ( 748) 2360 362.2 4.5e-99 NP_001230764 (OMIM: 600558,612253) signal transduc ( 748) 2360 362.2 4.5e-99 XP_006712782 (OMIM: 600558,612253) PREDICTED: sign ( 748) 2360 362.2 4.5e-99 XP_011510007 (OMIM: 600558,612253) PREDICTED: sign ( 748) 2360 362.2 4.5e-99 XP_011536999 (OMIM: 600556,616636) PREDICTED: sign ( 859) 1703 265.1 9e-70 XP_016860273 (OMIM: 600558,612253) PREDICTED: sign ( 500) 1573 245.7 3.5e-64 XP_011537000 (OMIM: 600556,616636) PREDICTED: sign ( 855) 1449 227.5 1.8e-58 NP_005410 (OMIM: 600556,616636) signal transducer ( 851) 1445 226.9 2.7e-58 NP_938146 (OMIM: 600556,616636) signal transducer ( 847) 1396 219.7 4.1e-56 XP_011537001 (OMIM: 600556,616636) PREDICTED: sign ( 592) 1327 209.4 3.6e-53 XP_016875393 (OMIM: 600556,616636) PREDICTED: sign ( 607) 1241 196.7 2.5e-49 XP_011537002 (OMIM: 600556,616636) PREDICTED: sign ( 615) 1219 193.4 2.4e-48 XP_005269168 (OMIM: 600556,616636) PREDICTED: sign ( 464) 939 151.9 5.5e-36 NP_003143 (OMIM: 601511) signal transducer and act ( 794) 913 148.2 1.3e-34 NP_001275647 (OMIM: 601511) signal transducer and ( 794) 913 148.2 1.3e-34 NP_036580 (OMIM: 245590,604260) signal transducer ( 787) 907 147.3 2.3e-34 XP_005257681 (OMIM: 601511) PREDICTED: signal tran ( 761) 904 146.9 3e-34 XP_016880466 (OMIM: 245590,604260) PREDICTED: sign ( 693) 874 142.4 6.1e-33 NP_001275648 (OMIM: 601511) signal transducer and ( 764) 827 135.5 8.2e-31 NP_001171552 (OMIM: 601512) signal transducer and ( 737) 603 102.4 7.4e-21 NP_001171551 (OMIM: 601512) signal transducer and ( 737) 603 102.4 7.4e-21 XP_006719638 (OMIM: 601512) PREDICTED: signal tran ( 847) 603 102.4 8.3e-21 NP_003144 (OMIM: 601512) signal transducer and act ( 847) 603 102.4 8.3e-21 NP_001171549 (OMIM: 601512) signal transducer and ( 847) 603 102.4 8.3e-21 NP_001171550 (OMIM: 601512) signal transducer and ( 847) 603 102.4 8.3e-21 XP_005257683 (OMIM: 245590,604260) PREDICTED: sign ( 497) 455 80.4 2.1e-14 NP_001275649 (OMIM: 601511) signal transducer and ( 763) 399 72.2 9.2e-12 XP_011537011 (OMIM: 601512) PREDICTED: signal tran ( 755) 298 57.3 2.9e-07 XP_011537010 (OMIM: 601512) PREDICTED: signal tran ( 755) 298 57.3 2.9e-07 XP_011537006 (OMIM: 601512) PREDICTED: signal tran ( 865) 298 57.3 3.2e-07 XP_011537008 (OMIM: 601512) PREDICTED: signal tran ( 865) 298 57.3 3.2e-07 XP_011537007 (OMIM: 601512) PREDICTED: signal tran ( 865) 298 57.3 3.2e-07 XP_011537009 (OMIM: 601512) PREDICTED: signal tran ( 865) 298 57.3 3.2e-07 XP_011537005 (OMIM: 601512) PREDICTED: signal tran ( 865) 298 57.3 3.2e-07 >>NP_003141 (OMIM: 102582,147060,615952) signal transduc (769 aa) initn: 5134 init1: 5134 opt: 5134 Z-score: 4116.6 bits: 772.5 E(85289): 0 Smith-Waterman score: 5134; 100.0% identity (100.0% similar) in 769 aa overlap (1-769:1-769) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT 670 680 690 700 710 720 730 740 750 760 pF1KB5 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM ::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM 730 740 750 760 >>XP_005257673 (OMIM: 102582,147060,615952) PREDICTED: s (769 aa) initn: 5134 init1: 5134 opt: 5134 Z-score: 4116.6 bits: 772.5 E(85289): 0 Smith-Waterman score: 5134; 100.0% identity (100.0% similar) in 769 aa overlap (1-769:1-769) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT 670 680 690 700 710 720 730 740 750 760 pF1KB5 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM 730 740 750 760 >>XP_016880464 (OMIM: 102582,147060,615952) PREDICTED: s (769 aa) initn: 5134 init1: 5134 opt: 5134 Z-score: 4116.6 bits: 772.5 E(85289): 0 Smith-Waterman score: 5134; 100.0% identity (100.0% similar) in 769 aa overlap (1-769:1-769) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT 670 680 690 700 710 720 730 740 750 760 pF1KB5 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM 730 740 750 760 >>XP_011523447 (OMIM: 102582,147060,615952) PREDICTED: s (770 aa) initn: 4751 init1: 4675 opt: 5122 Z-score: 4107.0 bits: 770.7 E(85289): 0 Smith-Waterman score: 5122; 99.9% identity (99.9% similar) in 770 aa overlap (1-769:1-770) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPG-AAPYLKTKFICVTPTTCSN :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN 670 680 690 700 710 720 720 730 740 750 760 pF1KB5 TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM 730 740 750 760 770 >>XP_005257674 (OMIM: 102582,147060,615952) PREDICTED: s (770 aa) initn: 4751 init1: 4675 opt: 5122 Z-score: 4107.0 bits: 770.7 E(85289): 0 Smith-Waterman score: 5122; 99.9% identity (99.9% similar) in 770 aa overlap (1-769:1-770) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPG-AAPYLKTKFICVTPTTCSN :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_005 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN 670 680 690 700 710 720 720 730 740 750 760 pF1KB5 TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM :::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM 730 740 750 760 770 >>NP_644805 (OMIM: 102582,147060,615952) signal transduc (770 aa) initn: 4751 init1: 4675 opt: 5122 Z-score: 4107.0 bits: 770.7 E(85289): 0 Smith-Waterman score: 5122; 99.9% identity (99.9% similar) in 770 aa overlap (1-769:1-770) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPG-AAPYLKTKFICVTPTTCSN :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_644 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN 670 680 690 700 710 720 720 730 740 750 760 pF1KB5 TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM :::::::::::::::::::::::::::::::::::::::::::::::::: NP_644 TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM 730 740 750 760 770 >>XP_016880462 (OMIM: 102582,147060,615952) PREDICTED: s (721 aa) initn: 4765 init1: 4765 opt: 4765 Z-score: 3822.1 bits: 717.9 E(85289): 3.7e-206 Smith-Waterman score: 4765; 100.0% identity (100.0% similar) in 714 aa overlap (1-714:1-714) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPFIDAVW 670 680 690 700 710 720 730 740 750 760 pF1KB5 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM XP_016 K >>XP_016880463 (OMIM: 102582,147060,615952) PREDICTED: s (721 aa) initn: 4765 init1: 4765 opt: 4765 Z-score: 3822.1 bits: 717.9 E(85289): 3.7e-206 Smith-Waterman score: 4765; 100.0% identity (100.0% similar) in 714 aa overlap (1-714:1-714) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPFIDAVW 670 680 690 700 710 720 730 740 750 760 pF1KB5 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM XP_016 K >>XP_016880465 (OMIM: 102582,147060,615952) PREDICTED: s (721 aa) initn: 4765 init1: 4765 opt: 4765 Z-score: 3822.1 bits: 717.9 E(85289): 3.7e-206 Smith-Waterman score: 4765; 100.0% identity (100.0% similar) in 714 aa overlap (1-714:1-714) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICVTPFIDAVW 670 680 690 700 710 720 730 740 750 760 pF1KB5 IDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM XP_016 K >>XP_016880461 (OMIM: 102582,147060,615952) PREDICTED: s (722 aa) initn: 4751 init1: 4675 opt: 4753 Z-score: 3812.5 bits: 716.1 E(85289): 1.3e-205 Smith-Waterman score: 4753; 99.9% identity (99.9% similar) in 715 aa overlap (1-714:1-715) 10 20 30 40 50 60 pF1KB5 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM 610 620 630 640 650 660 670 680 690 700 710 pF1KB5 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPG-AAPYLKTKFICVTPTTCSN :::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_016 DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPFIDAV 670 680 690 700 710 720 720 730 740 750 760 pF1KB5 TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM XP_016 WK 769 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:57:06 2016 done: Thu Nov 3 15:57:08 2016 Total Scan time: 11.700 Total Display time: 0.250 Function used was FASTA [36.3.4 Apr, 2011]