FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5096, 582 aa 1>>>pF1KB5096 582 - 582 aa - 582 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1845+/-0.00034; mu= 14.9641+/- 0.021 mean_var=89.6337+/-17.920, 0's: 0 Z-trim(117.4): 70 B-trim: 321 in 1/55 Lambda= 0.135469 statistics sampled from 29316 (29387) to 29316 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.345), width: 16 Scan time: 10.700 The best scores are: opt bits E(85289) NP_004986 (OMIM: 277950,600754) matrix metalloprot ( 582) 4072 806.0 0 NP_071913 (OMIM: 608482) matrix metalloproteinase- ( 562) 1255 255.4 3.7e-67 NP_005932 (OMIM: 602262) matrix metalloproteinase- ( 607) 1158 236.4 2e-61 XP_011526802 (OMIM: 604871) PREDICTED: matrix meta ( 556) 1134 231.7 4.8e-60 NP_057239 (OMIM: 602285) matrix metalloproteinase- ( 603) 1134 231.8 5.1e-60 XP_016883086 (OMIM: 604871) PREDICTED: matrix meta ( 591) 1130 231.0 8.7e-60 XP_016883087 (OMIM: 604871) PREDICTED: matrix meta ( 614) 1130 231.0 9e-60 NP_006681 (OMIM: 604871) matrix metalloproteinase- ( 645) 1130 231.0 9.3e-60 XP_011520904 (OMIM: 608482) PREDICTED: matrix meta ( 528) 1106 226.3 2e-58 XP_011520906 (OMIM: 608482) PREDICTED: matrix meta ( 478) 1095 224.1 8.3e-58 NP_002419 (OMIM: 602261) matrix metalloproteinase- ( 669) 1071 219.5 2.8e-56 XP_011536658 (OMIM: 602285) PREDICTED: matrix meta ( 519) 1005 206.5 1.8e-52 XP_011536659 (OMIM: 602285) PREDICTED: matrix meta ( 519) 1005 206.5 1.8e-52 XP_011536657 (OMIM: 602285) PREDICTED: matrix meta ( 519) 1005 206.5 1.8e-52 NP_005931 (OMIM: 185261) stromelysin-3 preproprote ( 488) 906 187.1 1.1e-46 XP_016874796 (OMIM: 602285) PREDICTED: matrix meta ( 434) 875 181.1 6.7e-45 XP_011520907 (OMIM: 608482) PREDICTED: matrix meta ( 352) 847 175.5 2.5e-43 NP_077278 (OMIM: 608417) matrix metalloproteinase- ( 520) 747 156.1 2.7e-37 NP_004762 (OMIM: 604629,612529) matrix metalloprot ( 483) 734 153.5 1.5e-36 XP_011523528 (OMIM: 608417) PREDICTED: matrix meta ( 435) 671 141.2 6.8e-33 XP_011523530 (OMIM: 608417) PREDICTED: matrix meta ( 435) 671 141.2 6.8e-33 XP_011523531 (OMIM: 608417) PREDICTED: matrix meta ( 435) 671 141.2 6.8e-33 XP_011523529 (OMIM: 608417) PREDICTED: matrix meta ( 435) 671 141.2 6.8e-33 NP_002420 (OMIM: 601807,611543) matrix metalloprot ( 508) 633 133.8 1.3e-30 XP_011523527 (OMIM: 608417) PREDICTED: matrix meta ( 445) 607 128.7 4e-29 NP_002413 (OMIM: 185250,614466) stromelysin-1 prep ( 477) 549 117.4 1.1e-25 XP_006719464 (OMIM: 601807,611543) PREDICTED: matr ( 279) 543 116.1 1.6e-25 NP_002416 (OMIM: 185260) stromelysin-2 preproprote ( 476) 544 116.4 2.2e-25 XP_011523532 (OMIM: 608417) PREDICTED: matrix meta ( 418) 539 115.4 3.8e-25 XP_011523533 (OMIM: 608417) PREDICTED: matrix meta ( 390) 531 113.8 1.1e-24 NP_116568 (OMIM: 608417) matrix metalloproteinase- ( 393) 531 113.8 1.1e-24 XP_016879050 (OMIM: 608482) PREDICTED: matrix meta ( 287) 510 109.6 1.4e-23 NP_002418 (OMIM: 250400,600108,602111) collagenase ( 471) 496 107.0 1.4e-22 NP_001289439 (OMIM: 120360,259600) 72 kDa type IV ( 584) 494 106.7 2.2e-22 NP_001289438 (OMIM: 120360,259600) 72 kDa type IV ( 584) 494 106.7 2.2e-22 NP_001289437 (OMIM: 120360,259600) 72 kDa type IV ( 584) 494 106.7 2.2e-22 NP_001121363 (OMIM: 120360,259600) 72 kDa type IV ( 610) 494 106.7 2.3e-22 NP_004521 (OMIM: 120360,259600) 72 kDa type IV col ( 660) 494 106.7 2.5e-22 NP_001139410 (OMIM: 120353,226600,606963) intersti ( 403) 487 105.2 4.3e-22 NP_002412 (OMIM: 120353,226600,606963) interstitia ( 469) 487 105.2 4.8e-22 NP_002414 (OMIM: 178990) matrilysin preproprotein ( 267) 479 103.6 8.9e-22 XP_011536661 (OMIM: 601807,611543) PREDICTED: matr ( 426) 480 103.9 1.2e-21 NP_002417 (OMIM: 601046) macrophage metalloelastas ( 470) 467 101.3 7.3e-21 XP_011541138 (OMIM: 120355) PREDICTED: neutrophil ( 377) 445 97.0 1.2e-19 XP_016873260 (OMIM: 120355) PREDICTED: neutrophil ( 444) 445 97.0 1.4e-19 NP_001291370 (OMIM: 120355) neutrophil collagenase ( 444) 445 97.0 1.4e-19 XP_011541137 (OMIM: 120355) PREDICTED: neutrophil ( 444) 445 97.0 1.4e-19 NP_001291371 (OMIM: 120355) neutrophil collagenase ( 444) 445 97.0 1.4e-19 NP_002415 (OMIM: 120355) neutrophil collagenase is ( 467) 445 97.0 1.4e-19 XP_011541136 (OMIM: 120355) PREDICTED: neutrophil ( 476) 445 97.0 1.4e-19 >>NP_004986 (OMIM: 277950,600754) matrix metalloproteina (582 aa) initn: 4072 init1: 4072 opt: 4072 Z-score: 4301.9 bits: 806.0 E(85289): 0 Smith-Waterman score: 4072; 100.0% identity (100.0% similar) in 582 aa overlap (1-582:1-582) 10 20 30 40 50 60 pF1KB5 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 FAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 LGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 SRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 WRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 WRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 WMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 WMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 NKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAA 490 500 510 520 530 540 550 560 570 580 pF1KB5 AVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV :::::::::::::::::::::::::::::::::::::::::: NP_004 AVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV 550 560 570 580 >>NP_071913 (OMIM: 608482) matrix metalloproteinase-25 p (562 aa) initn: 1174 init1: 245 opt: 1255 Z-score: 1326.7 bits: 255.4 E(85289): 3.7e-67 Smith-Waterman score: 1336; 40.6% identity (65.0% similar) in 566 aa overlap (12-556:10-557) 10 20 30 40 50 60 pF1KB5 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS :: :: : : :::. :.. . :: .:::::: .::.. NP_071 MRLRLRLLALLLLLLAPPARAPKPSAQDVSLGVD-WLTRYGYLPPPHPAQAQLQSPEK 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ : :: .::.: :: ::. : :. .::.:::..:: .:. . ::.:::..: :. NP_071 LRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVR-RRRRYALSGSVWK 60 70 80 90 100 110 130 140 150 160 170 pF1KB5 HNEITFCIQNYTPKVGEYATYEAIR----KAFRVWESATPLRFREVPYAYIREGHEKQAD . .:. .... :. .. . :..: :. .: . : :.:: .:.: : NP_071 KRTLTWRVRSF-PQSSQL-SQETVRVLMSYALMAWGMESGLTFHEVDSP---QGQE--PD 120 130 140 150 160 180 190 200 210 220 230 pF1KB5 IMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSAEPWTVRNEDLNGNDIFL :.: ::..:: :: :::: :: ::::.::: . :.::::::. : :: ..: .:.:.: NP_071 ILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB5 VAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDRRGIQQLYGGESGFPTKM :::::.:::::: ::: :..:: :::: : ... : .::: :.::::: : NP_071 VAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTPYDK 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB5 PPQPRTTSRPSVPDKP-KNPTYG-PNICDGNFDTVAMLRGEMFVFKERWFWRVR-NNQVM : . . :. : .: ..:.. :. :.::::..: .::: : :: ::::.. ..:.. NP_071 PTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLV 290 300 310 320 330 340 360 370 380 390 400 pF1KB5 DGYPMPIGQFWRGLPASI---NTAYER-KDGKFVFFKGDKHWVFDEASLEPGYPKHIKEL . : . .::.::::.. ..:: : .::....:.: . :::.. .:: : . . :: NP_071 SPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGG-ARPLTEL 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB5 GRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGS : : ...::.. : :::::. :: .:.:..: : ::.....::: : :: NP_071 GLP-PGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDV 410 420 430 440 450 460 470 480 490 500 510 pF1KB5 FMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCP--SGG----RPDEGTE- . :. :::.:: .::.: ....:.:: :. .:. :: :.: :: ..: NP_071 TV-SNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKATPV 470 480 490 500 510 520 520 530 540 550 560 570 pF1KB5 EETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLL :: :... .: . :. :::: : :: NP_071 SETCDCQCELNQAAGRWPA------PIPLLLLPLLVGGVASR 530 540 550 560 580 pF1KB5 DKV >>NP_005932 (OMIM: 602262) matrix metalloproteinase-16 p (607 aa) initn: 1674 init1: 962 opt: 1158 Z-score: 1223.8 bits: 236.4 E(85289): 2e-61 Smith-Waterman score: 2294; 56.7% identity (80.9% similar) in 570 aa overlap (33-582:41-607) 10 20 30 40 50 60 pF1KB5 PAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLS :. :.:::.:::::: : : . :: .... NP_005 RLDFVHHSGVFFLQTLLWILCATVCGTEQYFNVEVWLQKYGYLPPTDPRMSVLRSAETMQ 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB5 AAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHN .:.::::.:::...:::.: .:. :..:::::::. . : ..::::::. : ::::. NP_005 SALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYALTGQKWQHK 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB5 EITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFA .::. :.: :::::. : .:::.:: ::...::: :.::::. ...: ....:: :.:: NP_005 HITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENG-KRDVDITIIFA 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 EGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELG ::::::.:::::::::::::::::.::::::::: ::::. : . .:::.::::::::: NP_005 SGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLFLVAVHELG 190 200 210 220 230 240 250 260 270 280 290 pF1KB5 HALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPT----------- ::::::::.::.::::::::.:.:.:: ::.:: .:::..:: . .: NP_005 HALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTRPLPTVPPH 250 260 270 280 290 300 300 310 320 330 340 pF1KB5 -KMPP-QPRTTSRPSVPDKPKN-PTYG---PNICDGNFDTVAMLRGEMFVFKERWFWRVR ..:: .:: ..::. : : . :.: ::::::::.:.:.:: ::::::..:::::: NP_005 RSIPPADPRKNDRPKPPRPPTGRPSYPGAKPNICDGNFNTLAILRREMFVFKDQWFWRVR 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB5 NNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKE ::.::::::: : :::::: ::...:: .::.::::::.:.::: ...:.::::. . NP_005 NNRVMDGYPMQITYFWRGLPPSIDAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLIT 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB5 LGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRG :: :.: ::.:..: ::::::.:..:.:..::....: ::: : ::.::::::.: NP_005 LGSGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITVWKGIPESPQG 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB5 SFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGC--PSGGRPDEGTEEETE .:. ... :::::::..::::::: ::::::::.: :.:.::: :. : :: . NP_005 AFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMGCDGPTD-RVKEGHSPPDD 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB5 V-IIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV : :.:..:. .. .:.: :.:.: .: : .:.. .:: :.:.::::..:::.::. . : NP_005 VDIVIKLDNTAS-TVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYCKRSMQEWV 550 560 570 580 590 600 >>XP_011526802 (OMIM: 604871) PREDICTED: matrix metallop (556 aa) initn: 1519 init1: 660 opt: 1134 Z-score: 1199.0 bits: 231.7 E(85289): 4.8e-60 Smith-Waterman score: 1639; 46.4% identity (64.7% similar) in 586 aa overlap (18-582:65-556) 10 20 30 40 pF1KB5 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPP ...:.: :.. :. . ::..:::: : XP_011 LLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAP-FAGQNWLKSYGYLLP 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB5 GDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANV : :. . .: ..:..:...::.:::. ::: : :.. :..:::::::. ... XP_011 YDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDH--PHLSRRR 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB5 RRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYI : ::::. : ::....::. :.:::::::: : .:::.:: ::...::: :.:::: : XP_011 RNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEI 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB5 REGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNED . . .:.:::::::: ::::::.:::::::::::::::::.::::::::: ::::. : . XP_011 K-SDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNAN 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB5 LNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYG--G .:::.:::::::::::::::::::::::::::::.:.:.:: ::.:: .:::..:: . XP_011 HDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPA 280 290 300 310 320 330 290 300 310 320 pF1KB5 ESGFPTKMPP-----------------QPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAM : ::. : ::: :: . :.:..: ::::::::.:::. XP_011 EPLEPTRPLPTLPVRRIHSPSERKHERQPRPP-RPPLGDRPSTPGTKPNICDGNFNTVAL 340 350 360 370 380 330 340 350 360 370 380 pF1KB5 LRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHW .::::::::.:::::.:::.:..:::: : :::.:::: :..:::: ::.::::: XP_011 FRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKD---- 390 400 410 420 430 440 390 400 410 420 430 440 pF1KB5 VFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSE XP_011 ------------------------------------------------------------ 450 460 470 480 490 500 pF1KB5 YPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGC .:::::: ::::.::::.::::::.. ::::::: XP_011 -------------------------YTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGC 450 460 470 480 510 520 530 540 550 560 pF1KB5 PSGG--RPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHG . : : . .: :. . .. :.:.:.:::.: .: : .:.. ..: :. . XP_011 NQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKT 490 500 510 520 530 540 570 580 pF1KB5 TPRRLLYCQRSLLDKV :. . : .: . . : XP_011 GPQPVTYYKRPVQEWV 550 >>NP_057239 (OMIM: 602285) matrix metalloproteinase-17 p (603 aa) initn: 1061 init1: 219 opt: 1134 Z-score: 1198.5 bits: 231.8 E(85289): 5.1e-60 Smith-Waterman score: 1280; 38.6% identity (64.8% similar) in 546 aa overlap (3-518:9-531) 10 20 30 40 pF1KB5 MSPAPRPP----RCLLLPLLTLGTALASLGSAQSSSFSPEA--------WLQQY :.: :: : :::: : ::.. :. . . .:.: ::... NP_057 MRRRAARGPGPPPPGPGLSRLPLPLLLL-LALGTRGGCAAPAPAPRAEDLSLGVEWLSRF 10 20 30 40 50 50 60 70 80 90 100 pF1KB5 GYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAE :::::.: : .. . :: ::.:::.: ::..:: : :. :. :::..:: NP_057 GYLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPD---LP 60 70 80 90 100 110 110 120 130 140 150 pF1KB5 IKANVRRKRYAIQGLKWQHNEITFCIQNYTPK---VGEYATYEAIRKAFRVWESATPLRF . ...::.: : ::.. .... .... :. .:. .. . :..:: . .:: : NP_057 VLTQARRRRQAPAPTKWNKRNLSWRVRTF-PRDSPLGHDTVRALMYYALKVWSDIAPLNF 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB5 REVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSA .:: . :::.: :... :.:. :::: :: .:::.::: . .::::::. NP_057 HEVAGS--------AADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDD 180 190 200 210 220 220 230 240 250 260 270 pF1KB5 EPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDR : :: :. : .: :.: :::::.:::.:: : . .:: :.:: : . :: .:. NP_057 EAWTFRSSDAHGMDLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDK 230 240 250 260 270 280 280 290 300 310 320 pF1KB5 RGIQQLYG-GESGFPTKMPPQPRTTSRPSVPDKPKNPTYGP------NICDGNFDTVAML . :::: :: :: .: .: : .:. : : . .: . :. .::.::.. NP_057 VRVWQLYGVRESVSPTAQPEEP-----PLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQI 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB5 RGEMFVFKERWFWRV-RNNQVMDGYPMPIGQFWRGLPA---SINTAYER-KDGKFVFFKG ::: : :: ..:::. :. .... : . .:::::: :....::: .: :.::::: NP_057 RGEAFFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKG 350 360 370 380 390 400 390 400 410 420 430 440 pF1KB5 DKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRA :..::: . ..: :::. ..... :: ::::. : : .::::. . :.:.... : NP_057 DRYWVFKDNNVEEGYPRPVSDFS--LPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRH 410 420 430 440 450 460 450 460 470 480 490 500 pF1KB5 VDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRD .: :: . .:.:.: . .. :: . .::..:..::: . .:.: ::::.:. :: NP_057 MDPGYPAQSPLWRGVPSTLDDAMRWSDGA-SYFFRGQEYWKVLDGELEVAPGYPQSTARD 470 480 490 500 510 510 520 530 540 550 560 pF1KB5 WMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRR :. : : .:. NP_057 WLVC--GDSQADGSVAAGVDAAEGPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPL 520 530 540 550 560 570 >>XP_016883086 (OMIM: 604871) PREDICTED: matrix metallop (591 aa) initn: 1830 init1: 1043 opt: 1130 Z-score: 1194.4 bits: 231.0 E(85289): 8.7e-60 Smith-Waterman score: 1869; 49.9% identity (72.0% similar) in 567 aa overlap (18-582:65-591) 10 20 30 40 pF1KB5 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPP ...:.: :.. :. . ::..:::: : XP_016 LLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAP-FAGQNWLKSYGYLLP 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB5 GDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANV : :. . .: ..:..:...::.:::. ::: : :.. :..:::::::. ... XP_016 YDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDH--PHLSRRR 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB5 RRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYI : ::::. : ::....::. :.:::::::: : .:::.:: ::...::: :.:::: : XP_016 RNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEI 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB5 REGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNED . . .:.:::::::: ::::::.:::::::::::::::::.::::::::: :::: XP_016 K-SDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT----- 220 230 240 250 260 230 240 250 260 270 280 pF1KB5 LNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGES ::.: .:.. :. . : :: : :. : XP_016 -------------LGNA---NHDGPPAEPLEPTRP--------LPTLPVRRIH------S 270 280 290 290 300 310 320 330 340 pF1KB5 GFPTKMPPQPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNN : ::: :: . :.:..: ::::::::.:::..::::::::.:::::.::: XP_016 PSERKHERQPRPP-RPPLGDRPSTPGTKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNN 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB5 QVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELG .:..:::: : :::.:::: :..:::: ::.::::::::.::: :...:::::. . ::: XP_016 RVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELG 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB5 RGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSF :: . ::.:: : : ::::::.:..:.:..:: ::.: ::: : ::.:::..:.:.: XP_016 SCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAF 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB5 MGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGG--RPDEGTEEETEVI .... .:::::: ::::.::::.::::::.. ::::::: . : : . .: XP_016 ISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDVD 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB5 IIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV :. . .. :.:.:.:::.: .: : .:.. ..: :. . :. . : .: . . : XP_016 IMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV 540 550 560 570 580 590 >>XP_016883087 (OMIM: 604871) PREDICTED: matrix metallop (614 aa) initn: 1901 init1: 1043 opt: 1130 Z-score: 1194.1 bits: 231.0 E(85289): 9e-60 Smith-Waterman score: 2194; 55.8% identity (77.6% similar) in 568 aa overlap (36-582:51-614) 10 20 30 40 50 60 pF1KB5 RPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAI . ::..:::: : : :. . .: ..:..:. XP_016 QPLPSRMLKSQHFGRRRRRRRRRRLLSRVFQNWLKSYGYLLPYDSRASALHSAKALQSAV 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB5 AAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEIT ..::.:::. ::: : :.. :..:::::::. ... : ::::. : ::....:: XP_016 STMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDH--PHLSRRRRNKRYALTGQKWRQKHIT 90 100 110 120 130 130 140 150 160 170 180 pF1KB5 FCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGF . :.:::::::: : .:::.:: ::...::: :.:::: :. . .:.:::::::: :: XP_016 YSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIK-SDRKEADIMIFFASGF 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB5 HGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHAL ::::.:::::::::::::::::.::::::::: ::::. : . .:::.:::::::::::: XP_016 HGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHAL 200 210 220 230 240 250 250 260 270 280 290 pF1KB5 GLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYG--GESGFPTKMPP-------- :::::::::::::::::.:.:.:: ::.:: .:::..:: .: ::. : XP_016 GLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIH 260 270 280 290 300 310 300 310 320 330 340 pF1KB5 ---------QPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRN ::: :: . :.:..: ::::::::.:::..::::::::.:::::.:: XP_016 SPSERKHERQPRPP-RPPLGDRPSTPGTKPNICDGNFNTVALFRGEMFVFKDRWFWRLRN 320 330 340 350 360 370 350 360 370 380 390 400 pF1KB5 NQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKEL :.:..:::: : :::.:::: :..:::: ::.::::::::.::: :...:::::. . :: XP_016 NRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGEL 380 390 400 410 420 430 410 420 430 440 450 460 pF1KB5 GRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGS : :: . ::.:: : : ::::::.:..:.:..:: ::.: ::: : ::.:::..:.:. XP_016 GSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGA 440 450 460 470 480 490 470 480 490 500 510 520 pF1KB5 FMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGG--RPDEGTEEETEV :.... .:::::: ::::.::::.::::::.. ::::::: . : : . .: XP_016 FISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDV 500 510 520 530 540 550 530 540 550 560 570 580 pF1KB5 IIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV :. . .. :.:.:.:::.: .: : .:.. ..: :. . :. . : .: . . : XP_016 DIMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV 560 570 580 590 600 610 >>NP_006681 (OMIM: 604871) matrix metalloproteinase-24 p (645 aa) initn: 1908 init1: 1043 opt: 1130 Z-score: 1193.8 bits: 231.0 E(85289): 9.3e-60 Smith-Waterman score: 2203; 54.8% identity (77.1% similar) in 586 aa overlap (18-582:65-645) 10 20 30 40 pF1KB5 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPP ...:.: :.. :. . ::..:::: : NP_006 LLLLLLPALCCLPGAARAAAAAAGAGNRAAVAVAVARADEAEAP-FAGQNWLKSYGYLLP 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB5 GDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANV : :. . .: ..:..:...::.:::. ::: : :.. :..:::::::. ... NP_006 YDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDH--PHLSRRR 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB5 RRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYI : ::::. : ::....::. :.:::::::: : .:::.:: ::...::: :.:::: : NP_006 RNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEI 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB5 REGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNED . . .:.:::::::: ::::::.:::::::::::::::::.::::::::: ::::. : . NP_006 K-SDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNAN 220 230 240 250 260 270 230 240 250 260 270 280 pF1KB5 LNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYG--G .:::.:::::::::::::::::::::::::::::.:.:.:: ::.:: .:::..:: . NP_006 HDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPA 280 290 300 310 320 330 290 300 310 320 pF1KB5 ESGFPTKMPP-----------------QPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAM : ::. : ::: :: . :.:..: ::::::::.:::. NP_006 EPLEPTRPLPTLPVRRIHSPSERKHERQPRPP-RPPLGDRPSTPGTKPNICDGNFNTVAL 340 350 360 370 380 330 340 350 360 370 380 pF1KB5 LRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHW .::::::::.:::::.:::.:..:::: : :::.:::: :..:::: ::.::::::::.: NP_006 FRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYW 390 400 410 420 430 440 390 400 410 420 430 440 pF1KB5 VFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSE :: :...:::::. . ::: :: . ::.:: : : ::::::.:..:.:..:: ::.: NP_006 VFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPG 450 460 470 480 490 500 450 460 470 480 490 500 pF1KB5 YPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGC ::: : ::.:::..:.:.:.... .:::::: ::::.::::.::::::.. ::::::: NP_006 YPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGC 510 520 530 540 550 560 510 520 530 540 550 560 pF1KB5 PSGG--RPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHG . : : . .: :. . .. :.:.:.:::.: .: : .:.. ..: :. . NP_006 NQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKT 570 580 590 600 610 620 570 580 pF1KB5 TPRRLLYCQRSLLDKV :. . : .: . . : NP_006 GPQPVTYYKRPVQEWV 630 640 >>XP_011520904 (OMIM: 608482) PREDICTED: matrix metallop (528 aa) initn: 1033 init1: 245 opt: 1106 Z-score: 1169.8 bits: 226.3 E(85289): 2e-58 Smith-Waterman score: 1187; 40.2% identity (65.8% similar) in 497 aa overlap (81-556:44-523) 60 70 80 90 100 110 pF1KB5 RTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRK : :. .::.:::..:: .:. . ::. XP_011 KTPRHAEACVPGAKGALKSSGERPQPRALKDPGTVATMRKPRCSLPDVLGVAGLVR-RRR 20 30 40 50 60 70 120 130 140 150 160 pF1KB5 RYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIR----KAFRVWESATPLRFREVPYAY :::..: :.. .:. .... :. .. . :..: :. .: . : :.:: XP_011 RYALSGSVWKKRTLTWRVRSF-PQSSQL-SQETVRVLMSYALMAWGMESGLTFHEVDSP- 80 90 100 110 120 170 180 190 200 210 220 pF1KB5 IREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSAEPWTVRN .:.: ::.: ::..:: :: :::: :: ::::.::: . :.::::::. : :: . XP_011 --QGQE--PDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGS 130 140 150 160 170 180 230 240 250 260 270 280 pF1KB5 EDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDRRGIQQLY .: .:.:.: :::::.:::::: ::: :..:: :::: : ... : .::: :.:::: XP_011 KDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLY 190 200 210 220 230 240 290 300 310 320 330 340 pF1KB5 GGESGFPTKMPPQPRTTSRPSVPDKP-KNPTYG-PNICDGNFDTVAMLRGEMFVFKERWF : : : . . :. : .: ..:.. :. :.::::..: .::: : :: :: XP_011 GKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWF 250 260 270 280 290 300 350 360 370 380 390 pF1KB5 WRVR-NNQVMDGYPMPIGQFWRGLPASI---NTAYER-KDGKFVFFKGDKHWVFDEASLE ::.. ..:... : . .::.::::.. ..:: : .::....:.: . :::.. .:: XP_011 WRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLE 310 320 330 340 350 360 400 410 420 430 440 450 pF1KB5 PGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVW : . . ::: : ...::.. : :::::. :: .:.:..: : ::.....: XP_011 GG-ARPLTELGLP-PGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLW 370 380 390 400 410 420 460 470 480 490 500 510 pF1KB5 EGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCP--SGG-- :: : :: . :. :::.:: .::.: ....:.:: :. .:. :: :.: XP_011 EGAPPSPDDVTV-SNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPR 430 440 450 460 470 480 520 530 540 550 560 pF1KB5 --RPDEGTE-EETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPR :: ..: :: :... .: . :. :::: : :: XP_011 APRPPKATPVSETCDCQCELNQAAGRWPA------PIPLLLLPLLVGGVASR 490 500 510 520 570 580 pF1KB5 RLLYCQRSLLDKV >>XP_011520906 (OMIM: 608482) PREDICTED: matrix metallop (478 aa) initn: 1033 init1: 245 opt: 1095 Z-score: 1158.8 bits: 224.1 E(85289): 8.3e-58 Smith-Waterman score: 1176; 40.4% identity (65.9% similar) in 490 aa overlap (88-556:1-473) 60 70 80 90 100 110 pF1KB5 PQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGL ::.:::..:: .:. . ::.:::..: XP_011 MRKPRCSLPDVLGVAGLVR-RRRRYALSGS 10 20 120 130 140 150 160 170 pF1KB5 KWQHNEITFCIQNYTPKVGEYATYEAIR----KAFRVWESATPLRFREVPYAYIREGHEK :.. .:. .... :. .. . :..: :. .: . : :.:: .:.: XP_011 VWKKRTLTWRVRSF-PQSSQL-SQETVRVLMSYALMAWGMESGLTFHEVDSP---QGQE- 30 40 50 60 70 80 180 190 200 210 220 230 pF1KB5 QADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPN-IGGDTHFDSAEPWTVRNEDLNGND ::.: ::..:: :: :::: :: ::::.::: . :.::::::. : :: ..: .:.: XP_011 -PDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTD 90 100 110 120 130 140 240 250 260 270 280 290 pF1KB5 IFLVAVHELGHALGLEHSSDPSAIMAPFYQWM--DTENFVLPDDDRRGIQQLYGGESGFP .: :::::.:::::: ::: :..:: :::: : ... : .::: :.::::: : XP_011 LFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTP 150 160 170 180 190 200 300 310 320 330 340 pF1KB5 TKMPPQPRTTSRPSVPDKP-KNPTYG-PNICDGNFDTVAMLRGEMFVFKERWFWRVR-NN : . . :. : .: ..:.. :. :.::::..: .::: : :: ::::.. .. XP_011 YDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSG 210 220 230 240 250 260 350 360 370 380 390 400 pF1KB5 QVMDGYPMPIGQFWRGLPASI---NTAYER-KDGKFVFFKGDKHWVFDEASLEPGYPKHI :... : . .::.::::.. ..:: : .::....:.: . :::.. .:: : . . XP_011 QLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGG-ARPL 270 280 290 300 310 320 410 420 430 440 450 460 pF1KB5 KELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESP ::: : ...::.. : :::::. :: .:.:..: : ::.....::: : :: XP_011 TELGLP-PGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSP 330 340 350 360 370 380 470 480 490 500 510 pF1KB5 RGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCP--SGG----RPDEG . :. :::.:: .::.: ....:.:: :. .:. :: :.: :: .. XP_011 DDVTV-SNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKA 390 400 410 420 430 520 530 540 550 560 570 pF1KB5 TE-EETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQR : :: :... .: . :. :::: : :: XP_011 TPVSETCDCQCELNQAAGRWPA------PIPLLLLPLLVGGVASR 440 450 460 470 580 pF1KB5 SLLDKV 582 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:59:58 2016 done: Thu Nov 3 16:00:00 2016 Total Scan time: 10.700 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]