FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5103, 700 aa 1>>>pF1KB5103 700 - 700 aa - 700 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2068+/-0.000456; mu= 15.6153+/- 0.028 mean_var=142.8064+/-26.170, 0's: 0 Z-trim(114.3): 216 B-trim: 33 in 1/51 Lambda= 0.107325 statistics sampled from 23802 (24108) to 23802 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.283), width: 16 Scan time: 9.130 The best scores are: opt bits E(85289) NP_071920 (OMIM: 606178) hedgehog-interacting prot ( 700) 4896 770.9 0 XP_005263235 (OMIM: 606178) PREDICTED: hedgehog-in ( 682) 4773 751.9 1.9e-216 XP_006714351 (OMIM: 606178) PREDICTED: hedgehog-in ( 682) 4764 750.5 4.9e-216 NP_009122 (OMIM: 605186) wnt inhibitory factor 1 p ( 379) 245 50.5 1.4e-05 NP_001304101 (OMIM: 176290) protein delta homolog ( 310) 222 46.8 0.00015 NP_003827 (OMIM: 176290) protein delta homolog 1 i ( 383) 222 46.9 0.00017 XP_016864717 (OMIM: 121050,612570,616118) PREDICTE (2861) 230 49.1 0.00028 NP_001990 (OMIM: 121050,612570,616118) fibrillin-2 (2912) 230 49.1 0.00028 XP_016882865 (OMIM: 608529) PREDICTED: fibrillin-3 (2766) 228 48.8 0.00033 XP_016882864 (OMIM: 608529) PREDICTED: fibrillin-3 (2768) 228 48.8 0.00034 XP_016882862 (OMIM: 608529) PREDICTED: fibrillin-3 (2789) 228 48.8 0.00034 NP_001308360 (OMIM: 608529) fibrillin-3 precursor (2809) 228 48.8 0.00034 XP_016882861 (OMIM: 608529) PREDICTED: fibrillin-3 (2809) 228 48.8 0.00034 NP_115823 (OMIM: 608529) fibrillin-3 precursor [Ho (2809) 228 48.8 0.00034 XP_016882868 (OMIM: 608529) PREDICTED: fibrillin-3 (2851) 228 48.8 0.00034 NP_963845 (OMIM: 602319) protein kinase C-binding ( 763) 219 46.8 0.00037 XP_016882863 (OMIM: 608529) PREDICTED: fibrillin-3 (2777) 227 48.7 0.00037 NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 228 48.9 0.0004 NP_001275643 (OMIM: 602319) protein kinase C-bindi ( 753) 218 46.6 0.00041 NP_006148 (OMIM: 602319) protein kinase C-binding ( 810) 218 46.7 0.00043 NP_001275642 (OMIM: 602319) protein kinase C-bindi ( 838) 218 46.7 0.00044 NP_000129 (OMIM: 102370,129600,134797,154700,18490 (2871) 222 47.9 0.00065 NP_061947 (OMIM: 605185,616589) delta-like protein ( 685) 208 45.0 0.0011 XP_016884554 (OMIM: 600920,613619) PREDICTED: scav ( 617) 191 42.4 0.0065 NP_660142 (OMIM: 602570) protein jagged-2 isoform (1200) 195 43.3 0.0066 NP_002217 (OMIM: 602570) protein jagged-2 isoform (1238) 195 43.3 0.0068 XP_016870286 (OMIM: 608582) PREDICTED: epidermal g ( 219) 183 40.6 0.0077 XP_006717204 (OMIM: 608582) PREDICTED: epidermal g ( 219) 183 40.6 0.0077 NP_878315 (OMIM: 600920,613619) scavenger receptor ( 866) 191 42.5 0.0082 NP_699165 (OMIM: 600920,613619) scavenger receptor ( 871) 191 42.5 0.0082 >>NP_071920 (OMIM: 606178) hedgehog-interacting protein (700 aa) initn: 4896 init1: 4896 opt: 4896 Z-score: 4109.8 bits: 770.9 E(85289): 0 Smith-Waterman score: 4896; 100.0% identity (100.0% similar) in 700 aa overlap (1-700:1-700) 10 20 30 40 50 60 pF1KB5 MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRMMSQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRMMSQLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLSGGEMLCGGFYPRLSCCLRSDSPGLGRLENKIFSVTNNTECGKLLEEIKCALCSPHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LLSGGEMLCGGFYPRLSCCLRSDSPGLGRLENKIFSVTNNTECGKLLEEIKCALCSPHSQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SLFHSPEREVLERDLVLPLLCKDYCKEFFYTCRGHIPGFLQTTADEFCFYYARKDGGLCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SLFHSPEREVLERDLVLPLLCKDYCKEFFYTCRGHIPGFLQTTADEFCFYYARKDGGLCF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PDFPRKQVRGPASNYLDQMEEYDKVEEISRKHKHNCFCIQEVVSGLRQPVGALHSGDGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PDFPRKQVRGPASNYLDQMEEYDKVEEISRKHKHNCFCIQEVVSGLRQPVGALHSGDGSQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RLFILEKEGYVKILTPEGEIFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 RLFILEKEGYVKILTPEGEIFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQVDLRTARVFLEVAELHRKHLGGQLLFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 VSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQVDLRTARVFLEVAELHRKHLGGQLLFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 PDGFLYIILGDGMITLDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PDGFLYIILGDGMITLDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PPEVFAHGLHDPGRCAVDRHPTDININLTILCSDSNGKNRSSARILQIIKGKDYESEPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 PPEVFAHGLHDPGRCAVDRHPTDININLTILCSDSNGKNRSSARILQIIKGKDYESEPSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 LEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTKQWQEKPLCLGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTKQWQEKPLCLGTS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GSCRGYFSGHILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 GSCRGYFSGHILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKG 610 620 630 640 650 660 670 680 690 700 pF1KB5 YLGPQCEQVDRNIRRVTRAGILDQIIDMTSYLLDLTSYIV :::::::::::::::::::::::::::::::::::::::: NP_071 YLGPQCEQVDRNIRRVTRAGILDQIIDMTSYLLDLTSYIV 670 680 690 700 >>XP_005263235 (OMIM: 606178) PREDICTED: hedgehog-intera (682 aa) initn: 4804 init1: 4773 opt: 4773 Z-score: 4007.0 bits: 751.9 E(85289): 1.9e-216 Smith-Waterman score: 4773; 99.9% identity (99.9% similar) in 681 aa overlap (1-681:1-681) 10 20 30 40 50 60 pF1KB5 MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRMMSQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRMMSQLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLSGGEMLCGGFYPRLSCCLRSDSPGLGRLENKIFSVTNNTECGKLLEEIKCALCSPHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLSGGEMLCGGFYPRLSCCLRSDSPGLGRLENKIFSVTNNTECGKLLEEIKCALCSPHSQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SLFHSPEREVLERDLVLPLLCKDYCKEFFYTCRGHIPGFLQTTADEFCFYYARKDGGLCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLFHSPEREVLERDLVLPLLCKDYCKEFFYTCRGHIPGFLQTTADEFCFYYARKDGGLCF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PDFPRKQVRGPASNYLDQMEEYDKVEEISRKHKHNCFCIQEVVSGLRQPVGALHSGDGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDFPRKQVRGPASNYLDQMEEYDKVEEISRKHKHNCFCIQEVVSGLRQPVGALHSGDGSQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RLFILEKEGYVKILTPEGEIFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLFILEKEGYVKILTPEGEIFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQVDLRTARVFLEVAELHRKHLGGQLLFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQVDLRTARVFLEVAELHRKHLGGQLLFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 PDGFLYIILGDGMITLDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDGFLYIILGDGMITLDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PPEVFAHGLHDPGRCAVDRHPTDININLTILCSDSNGKNRSSARILQIIKGKDYESEPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPEVFAHGLHDPGRCAVDRHPTDININLTILCSDSNGKNRSSARILQIIKGKDYESEPSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 LEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTKQWQEKPLCLGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTKQWQEKPLCLGTS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GSCRGYFSGHILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSCRGYFSGHILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKG 610 620 630 640 650 660 670 680 690 700 pF1KB5 YLGPQCEQVDRNIRRVTRAGILDQIIDMTSYLLDLTSYIV ::::::::::::::::::: : XP_005 YLGPQCEQVDRNIRRVTRADIT 670 680 >>XP_006714351 (OMIM: 606178) PREDICTED: hedgehog-intera (682 aa) initn: 4764 init1: 4764 opt: 4764 Z-score: 3999.5 bits: 750.5 E(85289): 4.9e-216 Smith-Waterman score: 4764; 100.0% identity (100.0% similar) in 678 aa overlap (1-678:1-678) 10 20 30 40 50 60 pF1KB5 MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRMMSQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNPPKRLKRRDRRMMSQLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 LLSGGEMLCGGFYPRLSCCLRSDSPGLGRLENKIFSVTNNTECGKLLEEIKCALCSPHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLSGGEMLCGGFYPRLSCCLRSDSPGLGRLENKIFSVTNNTECGKLLEEIKCALCSPHSQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB5 SLFHSPEREVLERDLVLPLLCKDYCKEFFYTCRGHIPGFLQTTADEFCFYYARKDGGLCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLFHSPEREVLERDLVLPLLCKDYCKEFFYTCRGHIPGFLQTTADEFCFYYARKDGGLCF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB5 PDFPRKQVRGPASNYLDQMEEYDKVEEISRKHKHNCFCIQEVVSGLRQPVGALHSGDGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PDFPRKQVRGPASNYLDQMEEYDKVEEISRKHKHNCFCIQEVVSGLRQPVGALHSGDGSQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB5 RLFILEKEGYVKILTPEGEIFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLFILEKEGYVKILTPEGEIFKEPYLDIHKLVQSGIKGGDERGLLSLAFHPNYKKNGKLY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB5 VSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQVDLRTARVFLEVAELHRKHLGGQLLFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQVDLRTARVFLEVAELHRKHLGGQLLFG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB5 PDGFLYIILGDGMITLDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PDGFLYIILGDGMITLDDMEEMDGLSDFTGSVLRLDVDTDMCNVPYSIPRSNPHFNSTNQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB5 PPEVFAHGLHDPGRCAVDRHPTDININLTILCSDSNGKNRSSARILQIIKGKDYESEPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPEVFAHGLHDPGRCAVDRHPTDININLTILCSDSNGKNRSSARILQIIKGKDYESEPSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB5 LEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTKQWQEKPLCLGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LEFKPFSNGPLVGGFVYRGCQSERLYGSYVFGDRNGNFLTLQQSPVTKQWQEKPLCLGTS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB5 GSCRGYFSGHILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSCRGYFSGHILGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB5 AQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKG 610 620 630 640 650 660 670 680 690 700 pF1KB5 YLGPQCEQVDRNIRRVTRAGILDQIIDMTSYLLDLTSYIV :::::::::::::::::: XP_006 YLGPQCEQVDRNIRRVTRTSPR 670 680 >>NP_009122 (OMIM: 605186) wnt inhibitory factor 1 precu (379 aa) initn: 618 init1: 210 opt: 245 Z-score: 221.0 bits: 50.5 E(85289): 1.4e-05 Smith-Waterman score: 253; 40.8% identity (63.2% similar) in 76 aa overlap (594-668:264-339) 570 580 590 600 610 620 pF1KB5 ILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQPAQTLTSECSRLCRNG-YCTPTGK : .. : :.: . :::: : .: NP_009 PGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSK 240 250 260 270 280 290 630 640 650 660 670 680 pF1KB5 CCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNIRRVTRAGIL : :: :..::.: :::.: :.: .:::: :..:. : .:.. NP_009 CKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKRYEASLIHALRPAG 300 310 320 330 340 350 690 700 pF1KB5 DQIIDMTSYLLDLTSYIV NP_009 AQLRQHTPSLKKAEERRDPPESNYIW 360 370 >>NP_001304101 (OMIM: 176290) protein delta homolog 1 is (310 aa) initn: 181 init1: 134 opt: 222 Z-score: 202.8 bits: 46.8 E(85289): 0.00015 Smith-Waterman score: 222; 36.7% identity (58.2% similar) in 79 aa overlap (603-679:21-95) 580 590 600 610 620 630 pF1KB5 QTHNGKLYKIVDPKRPLMPEECRATVQPAQTLTSECSRLC--RNGYCTPTGKCCCSPGWE : .:: : .::.: . : :.:::. NP_001 MTATEALLRVLLLLLAFGHSTYGAECFPACNPQNGFCEDDNVCRCQPGWQ 10 20 30 40 50 640 650 660 670 680 690 pF1KB5 GDFCRTAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNIRRVTRAGILDQIIDMTS : .: :.: :: .: .:..:.: :. : : ::..: . : NP_001 GPLCDQCVTSPGCLHG-LCGEPGQCICTDGWDGELC---DRDVRACSSAPCANNGTCVSL 60 70 80 90 100 700 pF1KB5 YLLDLTSYIV NP_001 DDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNF 110 120 130 140 150 160 >>NP_003827 (OMIM: 176290) protein delta homolog 1 isofo (383 aa) initn: 181 init1: 134 opt: 222 Z-score: 201.7 bits: 46.9 E(85289): 0.00017 Smith-Waterman score: 222; 36.7% identity (58.2% similar) in 79 aa overlap (603-679:21-95) 580 590 600 610 620 630 pF1KB5 QTHNGKLYKIVDPKRPLMPEECRATVQPAQTLTSECSRLC--RNGYCTPTGKCCCSPGWE : .:: : .::.: . : :.:::. NP_003 MTATEALLRVLLLLLAFGHSTYGAECFPACNPQNGFCEDDNVCRCQPGWQ 10 20 30 40 50 640 650 660 670 680 690 pF1KB5 GDFCRTAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNIRRVTRAGILDQIIDMTS : .: :.: :: .: .:..:.: :. : : ::..: . : NP_003 GPLCDQCVTSPGCLHG-LCGEPGQCICTDGWDGELC---DRDVRACSSAPCANNGTCVSL 60 70 80 90 100 700 pF1KB5 YLLDLTSYIV NP_003 DDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNF 110 120 130 140 150 160 >>XP_016864717 (OMIM: 121050,612570,616118) PREDICTED: f (2861 aa) initn: 228 init1: 228 opt: 230 Z-score: 197.9 bits: 49.1 E(85289): 0.00028 Smith-Waterman score: 230; 41.9% identity (61.3% similar) in 62 aa overlap (607-668:148-209) 580 590 600 610 620 630 pF1KB5 GKLYKIVDPKRPLMPEECRATVQPAQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRT .:: : :: .: :. :. : .: XP_016 SCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQ 120 130 140 150 160 170 640 650 660 670 680 690 pF1KB5 AKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNIRRVTRAGILDQIIDMTSYLLDLT :: .:..:: :. ::.: : :. :::::. XP_016 PVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKT 180 190 200 210 220 230 700 pF1KB5 SYIV XP_016 LCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVG 240 250 260 270 280 290 >>NP_001990 (OMIM: 121050,612570,616118) fibrillin-2 pre (2912 aa) initn: 228 init1: 228 opt: 230 Z-score: 197.8 bits: 49.1 E(85289): 0.00028 Smith-Waterman score: 230; 41.9% identity (61.3% similar) in 62 aa overlap (607-668:148-209) 580 590 600 610 620 630 pF1KB5 GKLYKIVDPKRPLMPEECRATVQPAQTLTSECSRLCRNGYCTPTGKCCCSPGWEGDFCRT .:: : :: .: :. :. : .: NP_001 SCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQ 120 130 140 150 160 170 640 650 660 670 680 690 pF1KB5 AKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNIRRVTRAGILDQIIDMTSYLLDLT :: .:..:: :. ::.: : :. :::::. NP_001 PVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKT 180 190 200 210 220 230 700 pF1KB5 SYIV NP_001 LCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVG 240 250 260 270 280 290 >>XP_016882865 (OMIM: 608529) PREDICTED: fibrillin-3 iso (2766 aa) initn: 331 init1: 223 opt: 228 Z-score: 196.4 bits: 48.8 E(85289): 0.00033 Smith-Waterman score: 228; 36.1% identity (59.0% similar) in 83 aa overlap (591-668:98-180) 570 580 590 600 610 pF1KB5 EVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECR---ATVQPAQTLT--SECSRLCRNG :. : .:. :. .. : :: : :: XP_016 CCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNG 70 80 90 100 110 120 620 630 640 650 660 670 pF1KB5 YCTPTGKCCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNIRR ..: :. :. : : :. .:..:: :. ::.: : :..:::::. XP_016 GTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPC 130 140 150 160 170 180 680 690 700 pF1KB5 VTRAGILDQIIDMTSYLLDLTSYIV XP_016 FGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQD 190 200 210 220 230 240 >>XP_016882864 (OMIM: 608529) PREDICTED: fibrillin-3 iso (2768 aa) initn: 331 init1: 223 opt: 228 Z-score: 196.4 bits: 48.8 E(85289): 0.00034 Smith-Waterman score: 228; 36.1% identity (59.0% similar) in 83 aa overlap (591-668:98-180) 570 580 590 600 610 pF1KB5 EVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECR---ATVQPAQTLT--SECSRLCRNG :. : .:. :. .. : :: : :: XP_016 CCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNG 70 80 90 100 110 120 620 630 640 650 660 670 pF1KB5 YCTPTGKCCCSPGWEGDFCRTAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNIRR ..: :. :. : : :. .:..:: :. ::.: : :..:::::. XP_016 GTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPC 130 140 150 160 170 180 680 690 700 pF1KB5 VTRAGILDQIIDMTSYLLDLTSYIV XP_016 FGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQD 190 200 210 220 230 240 700 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:16:58 2016 done: Thu Nov 3 22:16:59 2016 Total Scan time: 9.130 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]